The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b

Toxicological Sciences

Volumn 99, Issue 1, 2007, Pages 43-50

  Iida, Mari ^a,b   Anna, Colleen H ^a   Gaskin, Nicole D ^a   Walker, Nigel J ^a   Devereux, Theodora R ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b Biosafety Research Center   (Japan)

Author keywords

Non genotoxic; SiRNA; Tumor suppressor gene

Indexed keywords

2 NITROTOLUENE; 4 NITROTOLUENE; EUGENOL; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; LEUCINE ZIPPER PROTEIN; METHYLEUGENOL; OXAZEPAM; PARACETAMOL; PIRINIXIC ACID; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA1 INDUCIBLE TRANSCIPT 4; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN 22; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; ENZYME INHIBITION; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENE TARGETING; LIVER CANCER; LIVER CARCINOGENESIS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIGENS, DIFFERENTIATION; CARCINOGENS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, INBRED STRAINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXAZEPAM; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEINS;

MURINAE; MUS;

EID: 34547859623     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm138     Document Type: Article

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