Patterns of expression of TSC-22 protein in astrocytic gliomas

Experimental Oncology

Volumn 27, Issue 4, 2005, Pages 314-318

  Shostak, K O ^a   Dmitrenko, V V ^a   Vudmaska, M I ^a   Naidenov, V G ^a   Beletskii, A V ^a   Matisheva, T A ^b   Semenova, V M ^b   Zozulya, Yu P ^b   Demotes Mainard, J ^c   Kavsan, V M ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY AND GENETICS   (Ukraine)

^b Institute of Neurosurgery Ams of Ukraine   (Ukraine)

^c BORDEAUX UNIVERSITY HOSPITAL   (France)

Author keywords

Astrocytic gliomas; Double immunohistochemical labeling; TSC 22 antibodies; TSC 22 gene

Indexed keywords

COMPLEMENTARY DNA; POLYCLONAL ANTIBODY; PROTEIN; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TSC 22 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; ASTROCYTE; BACTERIAL CELL; BRAIN TUMOR; CHROMOSOME 22Q; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION; GENE INACTIVATION; GLIOMA; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ASTROCYTES; ASTROCYTOMA; BASE SEQUENCE; BRAIN NEOPLASMS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 31344461581     PISSN: 18129269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK. The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 2002; 61: 215-25.
2. Collins VP. Brain tumors: classification and genes. J Neurol Neurosurg Psychiatry 2004; 75: ii2-11.
3. Barbashina V, Salazar P, Holland EC, Rosenblum MK, Ladanyi M. Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene. Clin Cancer Res 2005; 11: 1119-28.
4. Simons A, Jeuken JW, Eleweld MJ, Boerman RH, Geurts Van Kessel A. Isolation and characterization of glioblastoma-associated homozygously deleted DNA fragments from chromosomal region 9p21 suggests involvement of multiple tumour suppressor genes. J Pathol 1999; 189: 402-9.
5. Fujisawa H, Reis RM, Nakamura M, Colella S, Yonekawa Y, Kleihues P, Ohgaki H. Loss of heterozygosity oh chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas. Lab Invest 2000; 80: 65-72.
6. Sonoda Y, Iizuka M, Yasuda J, Makino R, Ono T, Kayama T, Yoshimoto T, Sekiya T. Loss of heterozygosity at 11p15 in malignant glioma. Cancer Res 1995; 55: 2166-8.
7. Ichimura K, Schmidt EE, Goike HM, Collins VP. Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene. Oncogene 1996; 13: 1065-72.
8. Saxena A, Clark WC, Robertson JT, Ikejiri B, Oldfield EH, Ali IU. Evidence for the involvement of a potential second tumor suppressor gene on chromosome 17 distinct from p53 in malignant astrocytomas. Cancer Res 1992; 52: 6716-21.
9. Rosenberg EJ, Lisle DK, Burwick JA, Ueki K, von Deimling A, Mohrenweiser HW, Louis DN. Refined deletion mapping of the chromosome 19qglioma tumor suppressor gene to the D19S412-STD interval. Oncogene 1996; 13: 2483-5.
10. Hartmann C, Numann A, Mueller W, Holtkamp N, Simon M, von Deimling A. Fine mapping of chromosome 22q tumor suppressor gene candidate regions in astrocytoma. Int J Cancer 2004; 108: 839-44.
11. Shostak KO, Dmitrenko W, Garifulin OM, Rozumenko VD, Khomenko OV, Zozulya YP, Zehetner G, Kavsan VM. Potential suppressor role of TSC-22 gene in human brain tumours. Biopolymeres Cell 2001; 17: 152-9.
12. Nakashiro K, Kawamata H, Hino S, Uchida D, Miwa Y, Hamano H, Omotehara F, Yoshida H, Sato M. Down-regulation of TSC-22 (transforming growth factor beta-stimulated clone 22) markedly enhances the growth of a human salivary gland cancer cell line in vitro and in vivo. Cancer Res 1998; 58: 549-55.
13. Sambrook J, Fritch EF, Maniatis T. Molecular cloning. A laboratory manual. 2nd ed. New York: Cold Spring Harbor Laboratory Press, 1989.
14. Sidorik LL, Gudzera OI, Dragovoz VA, Tukalo MA, Beresten SF. Immunochemical non-cross-reactivity between eukaryotic and prokaryotic seryl-tRNA synthetases. FEBS Lett 1991; 292: 76-8.
15. Cuny E, Loiseau H, Penchet G, Ellie E, Arsaut J, Vital A, Vincendeau P, Demotes-Mainard J. Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme. J Neurosurg 2002; 96: 294-301.
16. Dmitrenko VV, Shostak KO, Garifulin OM, Zozulya YA, Kavsan VM. Changes of gene expression in human astrocytic brain tumors. Exp Oncol 1998; 20: 191-7.
17. Zozulia IuA, Shostak EA, Garifulin OM, Rozumenko VD, Khomenko AV, Dmitrenko W, Kavsan VM. Role of gene expression changes in development of human brain gliomas. Zh Vopr Neirokhir 2002; 2: 43-9.
18. Kavsan V, Shostak K, Dmitrenko V, Chausovskiy T, Zozulya Y, Demotes-Mainard J. Peculiarities of molecular events in human glial tumors revealed by serial analysis of gene expression (SAGE). Exp Oncol 2004; 26: 196-204.
19. Shibanuma M, Kuroki T, Nose K. Isolation of a gene encoding a putative leucine zipper structure that is induced by transforming growth factor beta1 and other growth factors. J Biol Chem 1992; 267: 10219-24.
20. Kestler HA, Blanchetot C, den Hertog J, van der Saag PT, van der Burg B. Transforming growth factor beta stimulated clone TSC-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity. J Biol Chem 1999; 274: 27439-47.
21. Kawamata H, Nakashiro K, Uchida D, Hino S, Omotehara F, Yoshida H, Sato M. Induction of TSC-22 by treatment with a new anti-cancer drug, vesnarinone, in a human salivary gland cancer cell. Br J Cancer 1998; 77: 71-8.
22. Hino S, Kawamata H, Uchida D, Omotehara F, Miwa Y, Begum NM, Yoshida H, Fujimori T, Sato M. Nucleartranslocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant with apoptosis: TSC-22 as a putative transcriptional regulator. Biochem Biophys Res Commun 2000; 278: 659-64.
23. Shostak KO, Dmitrenko W, Garifulin OM, Rozumenko VD, Khomenko OV, Zozulya YA, Zehetner G, Kavsan VM. Downregulation of putative tumor suppressor gene TSC-22 in human brain tumors. J Surg Oncol 2003; 82: 57-64.
24. Alaminos M, Davalos V, Ropero S, Setien F, Paz MF, Herranz M, Fraga MF, Mora J, Cheung NK, Gerald WL, Esteller M. EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma. Cancer Res 2005; 65: 2565-71.
25. Estelter M. Aberrant DNA methylation as a cancer-inducing mechanism. Ann Rev Pharmacol Toxicol 2005; 45: 629-56.