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Volumn 70, Issue SUPPL. 1, 2012, Pages

The microbiota in inflammatory bowel disease: Friend, bystander, and sometime-villain

Author keywords

Crohn's disease; Inflammatory bowel disease; Ulcerative colitis

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; G PROTEIN COUPLED RECEPTOR; PURINERGIC P2X RECEPTOR; PURINERGIC P2Y RECEPTOR;

EID: 84864756966     PISSN: 00296643     EISSN: 17534887     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2012.00502.x     Document Type: Article
Times cited : (37)

References (71)
  • 2
    • 84858376593 scopus 로고    scopus 로고
    • The impact of the gut microbiota on human health: an integrative view
    • Clemente JC, Ursell LK, Parfrey LW, etal. The impact of the gut microbiota on human health: an integrative view. Cell. 2012;148:1258-1270.
    • (2012) Cell , vol.148 , pp. 1258-1270
    • Clemente, J.C.1    Ursell, L.K.2    Parfrey, L.W.3
  • 3
    • 77952318832 scopus 로고    scopus 로고
    • Intestinal bacteria and the regulation of immune cell homeostasis
    • Hill DA, Artis D. Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol. 2010;28:623-667.
    • (2010) Annu Rev Immunol , vol.28 , pp. 623-667
    • Hill, D.A.1    Artis, D.2
  • 4
    • 38649115342 scopus 로고    scopus 로고
    • Microbial influences in inflammatory bowel disease
    • Sartor RB. Microbial influences in inflammatory bowel disease. Gastroenterology. 2008;134:577-594.
    • (2008) Gastroenterology , vol.134 , pp. 577-594
    • Sartor, R.B.1
  • 5
    • 79955552936 scopus 로고    scopus 로고
    • Interactions between the host innate immune system and microbes in inflammatory bowel disease
    • Abraham C, Medzhitov R. Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology. 2011;140:1729-1737.
    • (2011) Gastroenterology , vol.140 , pp. 1729-1737
    • Abraham, C.1    Medzhitov, R.2
  • 6
    • 79955554300 scopus 로고    scopus 로고
    • The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases
    • Chassaing B, Darfeuille-Michaud A. The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases. Gastroenterology. 2011;140:1720-1728.
    • (2011) Gastroenterology , vol.140 , pp. 1720-1728
    • Chassaing, B.1    Darfeuille-Michaud, A.2
  • 7
    • 79958029177 scopus 로고    scopus 로고
    • Genes in inflammatory bowel disease: lessons from complex diseases
    • Henderson P, Satsangi J. Genes in inflammatory bowel disease: lessons from complex diseases. Clin Med. 2011;11:8-10.
    • (2011) Clin Med , vol.11 , pp. 8-10
    • Henderson, P.1    Satsangi, J.2
  • 8
    • 78650430453 scopus 로고    scopus 로고
    • Crohn disease. A current perspective on genetics, autophagy and immunity
    • Stappenbeck TS, Rioux JD, Mizoguchi A, etal. Crohn disease. A current perspective on genetics, autophagy and immunity. Autophagy. 2011;7:355-374.
    • (2011) Autophagy , vol.7 , pp. 355-374
    • Stappenbeck, T.S.1    Rioux, J.D.2    Mizoguchi, A.3
  • 9
    • 70649103789 scopus 로고    scopus 로고
    • Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
    • Barrett JC, Lee JC, Lees CW, etal. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet. 2009;41:1330-1334.
    • (2009) Nat Genet , vol.41 , pp. 1330-1334
    • Barrett, J.C.1    Lee, J.C.2    Lees, C.W.3
  • 10
    • 73849151394 scopus 로고    scopus 로고
    • NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
    • Cooney R, Baker J, Brain O, etal. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med. 2010;16:90-97.
    • (2010) Nat Med , vol.16 , pp. 90-97
    • Cooney, R.1    Baker, J.2    Brain, O.3
  • 11
    • 73849121209 scopus 로고    scopus 로고
    • Nod1 and Nod 2 direct authophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
    • Travassos LH, Carneiro LA, Ramjeet M, etal. Nod1 and Nod 2 direct authophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol. 2010;11:55-62.
    • (2010) Nat Immunol , vol.11 , pp. 55-62
    • Travassos, L.H.1    Carneiro, L.A.2    Ramjeet, M.3
  • 12
    • 77957993829 scopus 로고    scopus 로고
    • Inflammatory bowel disease - from mechanisms to treatment strategies
    • Melgar S, Shanahan F. Inflammatory bowel disease - from mechanisms to treatment strategies. Autoimmunity. 2010;43:1-15.
    • (2010) Autoimmunity , vol.43 , pp. 1-15
    • Melgar, S.1    Shanahan, F.2
  • 13
    • 70949087383 scopus 로고    scopus 로고
    • Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
    • Glocker E-O, Kotlarz D, Boztug K, etal. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N Engl J Med. 2009;361:2033-2045.
    • (2009) N Engl J Med , vol.361 , pp. 2033-2045
    • Glocker, E.-O.1    Kotlarz, D.2    Boztug, K.3
  • 14
    • 0023713859 scopus 로고
    • Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking
    • Tysk C, Lindberg E, Jarnerot G, etal. Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut. 1988;29:990-996.
    • (1988) Gut , vol.29 , pp. 990-996
    • Tysk, C.1    Lindberg, E.2    Jarnerot, G.3
  • 15
    • 78649693004 scopus 로고    scopus 로고
    • Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis
    • Sartor RB. Genetics and environmental interactions shape the intestinal microbiome to promote inflammatory bowel disease versus mucosal homeostasis. Gastroenterology. 2010;139:1816-1833.
    • (2010) Gastroenterology , vol.139 , pp. 1816-1833
    • Sartor, R.B.1
  • 16
    • 58749112734 scopus 로고    scopus 로고
    • A core gut microbiome in obese and lean twins
    • Turnbaugh PJ, Hamady M, Yatsunenko T, etal. A core gut microbiome in obese and lean twins. Nature. 2009;457:480-484.
    • (2009) Nature , vol.457 , pp. 480-484
    • Turnbaugh, P.J.1    Hamady, M.2    Yatsunenko, T.3
  • 17
    • 78649686679 scopus 로고    scopus 로고
    • A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    • Willing BP, Dicksved J, Halfarson J, etal. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology. 2010;139:1844-1854.
    • (2010) Gastroenterology , vol.139 , pp. 1844-1854
    • Willing, B.P.1    Dicksved, J.2    Halfarson, J.3
  • 18
    • 50249143099 scopus 로고    scopus 로고
    • Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases
    • Bernstein CN, Shanahan F. Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases. Gut. 2008;57:1185-1191.
    • (2008) Gut , vol.57 , pp. 1185-1191
    • Bernstein, C.N.1    Shanahan, F.2
  • 19
    • 84875564874 scopus 로고    scopus 로고
    • Smoking cessation leads to profound changes in the composition of the intestinal microbiota - a controlled prospective interventional study using terminal restriction fragment length polymorphism and pyrosequencing. In: Program and abstracts of Digestive Disease Week 2011; 7-11 May 2011; Chicago. Abstract 858
    • Biedermann L, Zeitz J, Sutter-Minder E, etal. Smoking cessation leads to profound changes in the composition of the intestinal microbiota - a controlled prospective interventional study using terminal restriction fragment length polymorphism and pyrosequencing. In: Program and abstracts of Digestive Disease Week 2011; 7-11 May 2011; Chicago. Abstract 858.
    • Biedermann, L.1    Zeitz, J.2    Sutter-Minder, E.3
  • 20
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol. 2009;9:313-323.
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 22
    • 77950353786 scopus 로고    scopus 로고
    • Homeostasis and inflammation in the intestine
    • Garrett WS, Gordon JI, Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 2010;140:859-870.
    • (2010) Cell , vol.140 , pp. 859-870
    • Garrett, W.S.1    Gordon, J.I.2    Glimcher, L.H.3
  • 23
    • 70449703996 scopus 로고    scopus 로고
    • What are the consequences of the disappearing microbiota?
    • Blaser MJ, Falkow S. What are the consequences of the disappearing microbiota? Nat Rev Microbiol. 2009;7:887-894.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 887-894
    • Blaser, M.J.1    Falkow, S.2
  • 24
    • 67449110978 scopus 로고    scopus 로고
    • Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions
    • Fumagalli M, Pozzoli U, Cagliani R, etal. Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions. J Exp Med. 2009;206:1395-1408.
    • (2009) J Exp Med , vol.206 , pp. 1395-1408
    • Fumagalli, M.1    Pozzoli, U.2    Cagliani, R.3
  • 25
    • 0029926387 scopus 로고    scopus 로고
    • Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan
    • Shoda R, Matsueda K, Yamato S, etal. Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr. 1996;63:741-745.
    • (1996) Am J Clin Nutr , vol.63 , pp. 741-745
    • Shoda, R.1    Matsueda, K.2    Yamato, S.3
  • 26
    • 70350110294 scopus 로고    scopus 로고
    • High-fat diet determines the composition of the murine gut microbiome independently of obesity
    • Hildebrandt MA, Hoffmann C, Sherrill-Mix SA, etal. High-fat diet determines the composition of the murine gut microbiome independently of obesity. Gastroenterology. 2009;137:1716-1724.
    • (2009) Gastroenterology , vol.137 , pp. 1716-1724
    • Hildebrandt, M.A.1    Hoffmann, C.2    Sherrill-Mix, S.A.3
  • 27
    • 78649887273 scopus 로고    scopus 로고
    • Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models
    • Murphy EF, Cotter PD, Healy S, etal. Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models. Gut. 2010;59:1635-1642.
    • (2010) Gut , vol.59 , pp. 1635-1642
    • Murphy, E.F.1    Cotter, P.D.2    Healy, S.3
  • 28
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by comparative study in children from Europe and rural Africa
    • De Filippo C, Cavalieri D, Di Paola M, etal. Impact of diet in shaping gut microbiota revealed by comparative study in children from Europe and rural Africa. Proc Natl Acad Sci USA. 2010;107:14691-14696.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14691-14696
    • De Filippo, C.1    Cavalieri, D.2    Di Paola, M.3
  • 29
    • 79959409252 scopus 로고    scopus 로고
    • The hybrid science of diet, microbes and metabolic health
    • Shanahan F, Murphy E. The hybrid science of diet, microbes and metabolic health. Am J Clin Nutr. 2011;94:1-2.
    • (2011) Am J Clin Nutr , vol.94 , pp. 1-2
    • Shanahan, F.1    Murphy, E.2
  • 30
    • 79956301905 scopus 로고    scopus 로고
    • Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans
    • Muegge BD, Kuczynski J, Knights D, etal. Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science. 2011;332:970-974.
    • (2011) Science , vol.332 , pp. 970-974
    • Muegge, B.D.1    Kuczynski, J.2    Knights, D.3
  • 31
    • 79959855078 scopus 로고    scopus 로고
    • Predicting a human gut microbiota's response to diet in gnotobiotic mice
    • Faith JJ, McNulty NP, Rey FE, etal. Predicting a human gut microbiota's response to diet in gnotobiotic mice. Science. 2011;333:101-104.
    • (2011) Science , vol.333 , pp. 101-104
    • Faith, J.J.1    McNulty, N.P.2    Rey, F.E.3
  • 32
    • 78651252504 scopus 로고    scopus 로고
    • Antibiotic use in inflammatory bowel diseases in childhood
    • Hviid A, Svanström H, Frisch M. Antibiotic use in inflammatory bowel diseases in childhood. Gut. 2011;60:49-54.
    • (2011) Gut , vol.60 , pp. 49-54
    • Hviid, A.1    Svanström, H.2    Frisch, M.3
  • 33
    • 78649868190 scopus 로고    scopus 로고
    • Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease
    • Shaw SY, Blanchard JF, Bernstein CN. Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease. Am J Gastroenterol. 2010;105:2687-2692.
    • (2010) Am J Gastroenterol , vol.105 , pp. 2687-2692
    • Shaw, S.Y.1    Blanchard, J.F.2    Bernstein, C.N.3
  • 34
    • 0030588647 scopus 로고    scopus 로고
    • Are all diseases infectious?
    • Lorber B. Are all diseases infectious? Ann Intern Med. 1996;125:844-851.
    • (1996) Ann Intern Med , vol.125 , pp. 844-851
    • Lorber, B.1
  • 35
    • 76949107790 scopus 로고    scopus 로고
    • Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens
    • Lebeer S, Vanderleyden J, De Keersmaecker SCJ. Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol. 2010;8:171-184.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 171-184
    • Lebeer, S.1    Vanderleyden, J.2    De Keersmaecker, S.C.J.3
  • 36
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round JL, Lee SM, Li J, etal. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science. 2011;332:974-977.
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3
  • 37
    • 77953904042 scopus 로고    scopus 로고
    • Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
    • Cadwell K, Patel KK, Maloney NS, etal. Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine. Cell. 2010;141:1135-1145.
    • (2010) Cell , vol.141 , pp. 1135-1145
    • Cadwell, K.1    Patel, K.K.2    Maloney, N.S.3
  • 38
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J, etal. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. 2010;464:59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 40
    • 41149172642 scopus 로고    scopus 로고
    • Detection of Mycobacterium avium subspecies paratuberculosis from patients with Crohn's disease using nucleic acid-based techniques: a systematic review and meta-analysis
    • Abubakar I, Myhill D, Aliyu SH, etal. Detection of Mycobacterium avium subspecies paratuberculosis from patients with Crohn's disease using nucleic acid-based techniques: a systematic review and meta-analysis. Inflamm Bowel Dis. 2008;14:401-410.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 401-410
    • Abubakar, I.1    Myhill, D.2    Aliyu, S.H.3
  • 41
    • 4143069158 scopus 로고    scopus 로고
    • High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
    • Darfeuille-Michaud A, Boudeau J, Bulois P, etal. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology. 2004;127:412-421.
    • (2004) Gastroenterology , vol.127 , pp. 412-421
    • Darfeuille-Michaud, A.1    Boudeau, J.2    Bulois, P.3
  • 42
    • 66949151443 scopus 로고    scopus 로고
    • The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission
    • Clayton EM, Rea MC, Shanahan F, etal. The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission. Am J Gastroenterol. 2009;104:1162-1169.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1162-1169
    • Clayton, E.M.1    Rea, M.C.2    Shanahan, F.3
  • 43
    • 44649118583 scopus 로고    scopus 로고
    • Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases
    • Peterson DA, Frank DN, Pace NR, etal. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe. 2008;3:417-427.
    • (2008) Cell Host Microbe , vol.3 , pp. 417-427
    • Peterson, D.A.1    Frank, D.N.2    Pace, N.R.3
  • 44
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L, etal. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA. 2008;105:16731-16736.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3
  • 45
    • 77955300097 scopus 로고    scopus 로고
    • Microbiota in pediatric inflammatory bowel disease
    • Schwiertz A, Jacobi M, Frick J-S, etal. Microbiota in pediatric inflammatory bowel disease. J Pediatr 2010;157:240-244.e1.
    • (2010) J Pediatr , vol.157
    • Schwiertz, A.1    Jacobi, M.2    Frick, J.-S.3
  • 46
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank DN, St. Amand AL, Feldman RA, etal. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA. 2007;104:13780-13785.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3
  • 47
    • 79953839845 scopus 로고    scopus 로고
    • Degradation of the extracellular matrix components by bacterial-derived metalloproteases: implications for inflammatory bowel diseases
    • Pruteanu M, Hyland NP, Clarke DJ, etal. Degradation of the extracellular matrix components by bacterial-derived metalloproteases: implications for inflammatory bowel diseases. Inflamm Bowel Dis. 2011;17:1189-1200.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1189-1200
    • Pruteanu, M.1    Hyland, N.P.2    Clarke, D.J.3
  • 48
    • 57749189066 scopus 로고    scopus 로고
    • Host-bacteria interaction in inflammatory bowel disease
    • Knight P, Campbell BJ, Rhodes JM. Host-bacteria interaction in inflammatory bowel disease. Br Med Bull. 2008;88:95-113.
    • (2008) Br Med Bull , vol.88 , pp. 95-113
    • Knight, P.1    Campbell, B.J.2    Rhodes, J.M.3
  • 49
    • 70349756909 scopus 로고    scopus 로고
    • The immunopathogenesis of Crohn's disease: a three-stage model
    • Sewell GW, Marks DJB, Segal AW. The immunopathogenesis of Crohn's disease: a three-stage model. Curr Opin Immunol. 2009;21:506-513.
    • (2009) Curr Opin Immunol , vol.21 , pp. 506-513
    • Sewell, G.W.1    Marks, D.J.B.2    Segal, A.W.3
  • 50
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature. 2008;453:620-625.
    • (2008) Nature , vol.453 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 52
    • 79955551587 scopus 로고    scopus 로고
    • Regulation of homeostasis and inflammation in the intestine
    • MacDonald TT, Monteleone I, Fantini MC, etal. Regulation of homeostasis and inflammation in the intestine. Gastroenterology. 2011;140:1768-1775.
    • (2011) Gastroenterology , vol.140 , pp. 1768-1775
    • MacDonald, T.T.1    Monteleone, I.2    Fantini, M.C.3
  • 53
    • 70350666634 scopus 로고    scopus 로고
    • Regulation of immunomodulatory responses by gut microbiota and chemoattractant receptor GPR43
    • Maslowski KM, Vieira AT, Ng A, etal. Regulation of immunomodulatory responses by gut microbiota and chemoattractant receptor GPR43. Nature. 2009;461:1282-1286.
    • (2009) Nature , vol.461 , pp. 1282-1286
    • Maslowski, K.M.1    Vieira, A.T.2    Ng, A.3
  • 54
    • 79251584066 scopus 로고    scopus 로고
    • Bifidobacteria can protect from enteropathogenic infection through production of acetate
    • Fukuda S, Toh H, Hase K, etal. Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature. 2011;469:543-547.
    • (2011) Nature , vol.469 , pp. 543-547
    • Fukuda, S.1    Toh, H.2    Hase, K.3
  • 55
    • 1242296822 scopus 로고    scopus 로고
    • Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
    • Suzuki K, Meek B, Doi Y, etal. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc Natl Acad Sci USA. 2004;101:1981-1986.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1981-1986
    • Suzuki, K.1    Meek, B.2    Doi, Y.3
  • 56
    • 54549122338 scopus 로고    scopus 로고
    • Innate immunity and intestinal microbiota in the development of type 1 diabetes
    • Wen L, Ley RE, Volchkov PV, etal. Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature. 2008;455:1109-1113.
    • (2008) Nature , vol.455 , pp. 1109-1113
    • Wen, L.1    Ley, R.E.2    Volchkov, P.V.3
  • 57
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
    • Vijay-Kumar M, Aitken JD, Carvalho FA, etal. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science. 2010;328:228-231.
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1    Aitken, J.D.2    Carvalho, F.A.3
  • 58
    • 34848889673 scopus 로고    scopus 로고
    • Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    • Garrett WS, Lord GM, Punit S, etal. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 2007;131:33-45.
    • (2007) Cell , vol.131 , pp. 33-45
    • Garrett, W.S.1    Lord, G.M.2    Punit, S.3
  • 59
    • 77956569409 scopus 로고    scopus 로고
    • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
    • Garrett WS, Gallini CA, Yatsunenko T, etal. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Gell Host Microbe. 2010;8:292-300.
    • (2010) Gell Host Microbe , vol.8 , pp. 292-300
    • Garrett, W.S.1    Gallini, C.A.2    Yatsunenko, T.3
  • 60
    • 79956078164 scopus 로고    scopus 로고
    • Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
    • Bloom SM, Bijanki VN, Nava GM, etal. Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe. 2011;9:390-403.
    • (2011) Cell Host Microbe , vol.9 , pp. 390-403
    • Bloom, S.M.1    Bijanki, V.N.2    Nava, G.M.3
  • 61
    • 79957576718 scopus 로고    scopus 로고
    • NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
    • Elinav E, Strowig T, Kau AL, etal. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell. 2011;145:1-13.
    • (2011) Cell , vol.145 , pp. 1-13
    • Elinav, E.1    Strowig, T.2    Kau, A.L.3
  • 63
    • 78649712604 scopus 로고    scopus 로고
    • Probiotics in perspective
    • Shanahan F. Probiotics in perspective. Gastroenterology. 2010;139:1808-1812.
    • (2010) Gastroenterology , vol.139 , pp. 1808-1812
    • Shanahan, F.1
  • 64
    • 79953805710 scopus 로고    scopus 로고
    • An evidence-based systematic review on medical therapies for inflammatory bowel disease
    • Talley NJ, Abreu MT, Achkar J-P, etal. An evidence-based systematic review on medical therapies for inflammatory bowel disease. Am J Gastroenterol. 2011;106(Suppl 1):S2-S25.
    • (2011) Am J Gastroenterol , vol.106 , Issue.SUPPL. 1
    • Talley, N.J.1    Abreu, M.T.2    Achkar, J.-P.3
  • 65
    • 79960291846 scopus 로고    scopus 로고
    • Molecular mechanisms of probiotic action: it's all in the strains!
    • Shanahan F. Molecular mechanisms of probiotic action: it's all in the strains! Gut. 2011;60:1026-1027.
    • (2011) Gut , vol.60 , pp. 1026-1027
    • Shanahan, F.1
  • 66
    • 79960302320 scopus 로고    scopus 로고
    • Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide
    • Macho Fernandez E, Valenti V, Rockel C, etal. Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide. Gut. 2011;60:1050-1059.
    • (2011) Gut , vol.60 , pp. 1050-1059
    • Macho Fernandez, E.1    Valenti, V.2    Rockel, C.3
  • 67
    • 0034714188 scopus 로고    scopus 로고
    • Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
    • Steidler L, Hans W, Schotte L, etal. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science. 2000;289:1352-1355.
    • (2000) Science , vol.289 , pp. 1352-1355
    • Steidler, L.1    Hans, W.2    Schotte, L.3
  • 68
    • 33744933432 scopus 로고    scopus 로고
    • A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease
    • Braat H, Rottiers P, Hommes DW, etal. A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease. Clin Gastroenterol Hepatol. 2006;4:754-759.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 754-759
    • Braat, H.1    Rottiers, P.2    Hommes, D.W.3
  • 69
    • 77249133143 scopus 로고    scopus 로고
    • Orally administered L. lactis secreting an anti-TNF nanobody demonstrate efficacy in chronic colitis
    • Vandenbroucke K, de Haard H, Beirnaert E, etal. Orally administered L. lactis secreting an anti-TNF nanobody demonstrate efficacy in chronic colitis. Mucosal Immunol. 2009;3:49-56.
    • (2009) Mucosal Immunol , vol.3 , pp. 49-56
    • Vandenbroucke, K.1    de Haard, H.2    Beirnaert, E.3
  • 70
    • 77950799444 scopus 로고    scopus 로고
    • Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus
    • Hamady ZZ, Scott N, Farrar MD, etal. Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus. Gut. 2010;59:461-469.
    • (2010) Gut , vol.59 , pp. 461-469
    • Hamady, Z.Z.1    Scott, N.2    Farrar, M.D.3
  • 71
    • 80051504591 scopus 로고    scopus 로고
    • Treatment of colitis with a commensal gut bacterium engineered to secrete human TGF-β1 under the control of dietary xylan 1
    • Hamady ZZ, Scott N, Farrar MD, etal. Treatment of colitis with a commensal gut bacterium engineered to secrete human TGF-β1 under the control of dietary xylan 1. Inflamm Bowel Dis. 2011;17:1925-1935.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1925-1935
    • Hamady, Z.Z.1    Scott, N.2    Farrar, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.