Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cell trafficking

European Journal of Immunology

Volumn 42, Issue 8, 2012, Pages 2073-2086

  Makidon, Paul E ^a,b   Belyakov, Igor M ^a,b   Blanco, Luz P ^b   Janczak, Katarzyna W ^a,b   Landers, Jeffrey ^a,b   Bielinska, Anna U ^a,b   Groom, Jeffrey V ^a,b   Baker, James R ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Adjuvants; Cytokines; DCs; Epithelial cells; Mucosal vaccines

Indexed keywords

CALRETICULIN; CD11B ANTIGEN; CD19 ANTIGEN; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GREEN FLUORESCENT PROTEIN; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; QUANTUM DOT; RANTES; THYMIC STROMAL LYMPHOPOIETIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; WATER OIL CREAM;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTATION; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL MIGRATION; CERVICAL LYMPH NODE; CILIATED EPITHELIUM; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IN VIVO STUDY; INNATE IMMUNITY; LYMPHATIC DRAINAGE; LYMPHOID TISSUE; MOUSE; NANOEMULSION; NONHUMAN; NOSE MUCOSA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CALRETICULIN; CELL MOVEMENT; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; EMULSIONS; EPITHELIAL CELLS; GENES, MHC CLASS II; INTERLEUKIN-6; LYMPHOID TISSUE; MICE; MICE, INBRED C57BL; NASAL MUCOSA;

EID: 84864746501     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201142346     Document Type: Article

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