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Volumn 32, Issue 3, 2012, Pages 274-288

Klebsiella spp as a 1,3-propanediol producer the metabolic engineering approach

Author keywords

1; 3 propanediol; Cofactor engineering; Glycerol fermentation; Klebsiella; Metabolic engineering; Protein engineering

Indexed keywords

3-PROPANEDIOL; COFACTOR ENGINEERING; GLYCEROL FERMENTATION; KLEBSIELLA; PROTEIN ENGINEERING;

EID: 84864723989     PISSN: 07388551     EISSN: 15497801     Source Type: Journal    
DOI: 10.3109/07388551.2011.616859     Document Type: Review
Times cited : (48)

References (67)
  • 1
    • 0029879143 scopus 로고    scopus 로고
    • Glycerol dehydratase activity: The limiting step for 1,3-propanediol production by Clostridium butyricum DSM 5431
    • Abbad-Andaloussi S., Guedon E., Spiesser E., Petitdemange H. Glycerol dehydratase activity: the limiting step for 1,3-propanediol production by Clostridium butyricum DSM 5431. Lett. Appl. Microbiol., 1996; 22, 311-4. (Pubitemid 26122370)
    • (1996) Letters in Applied Microbiology , vol.22 , Issue.4 , pp. 311-314
    • Abbad-Andaloussi, S.1    Guedon, E.2    Spiesser, E.3    Petitdemange, H.4
  • 3
    • 0029917322 scopus 로고    scopus 로고
    • 3-Hydroxypropionaldehyde, an inhibitory metabolite of glycerol fermentation to 1,3-propanediol by enterobacterial species
    • Barbirato F., Grivet J.P., Soucaille P., Bories A. 3- Hydroxypropionaldehyde, an inhibitory metabolite of glycerol fermentation to 1,3-propanediol by enterobacterial species. Appl. Environ. Microbiol., 1996; 62, 1448-51. (Pubitemid 26114789)
    • (1996) Applied and Environmental Microbiology , vol.62 , Issue.4 , pp. 1448-1451
    • Barbirato, F.1    Grivet, J.P.2    Soucaille, P.3    Bories, A.4
  • 6
    • 68349139739 scopus 로고    scopus 로고
    • Regulation of 3-hydroxypropionaldehyde accumulation in Klebsiella pneumoniae by overexpression of dhaT and dhaD genes
    • Chen Z., Liu H., Liu D. Regulation of 3-hydroxypropionaldehyde accumulation in Klebsiella pneumoniae by overexpression of dhaT and dhaD genes. Enzyme Microb Technol., 2009; 45(4), 305-9.
    • (2009) Enzyme Microb Technol. , vol.45 , Issue.4 , pp. 305-309
    • Chen, Z.1    Liu, H.2    Liu, D.3
  • 7
    • 0042477577 scopus 로고    scopus 로고
    • Stoichiometric analysis and experimental investigation of glycerol bioconversion to 1,3-propanediol by Klebsiella pneumoniae under microaerobic conditions
    • DOI 10.1016/S0141-0229(03)00135-2
    • Chen X., Xiu Z., Wang J., Zhang D., Xu P. Stoichiometric analysis and experimental investigation of glycerol bioconversion to 1,3-propanediol by Klebsiella pneumoniae under microaerobic conditions. Enzyme Microb Technol., 2003; 33, 386-94. (Pubitemid 37020914)
    • (2003) Enzyme and Microbial Technology , vol.33 , Issue.4 , pp. 386-394
    • Chen, X.1    Xiu, Z.2    Wang, J.3    Zhang, D.4    Xu, P.5
  • 8
    • 13844257280 scopus 로고    scopus 로고
    • Multiple growth inhibition of Klebsiella pneumoniae in 1,3-propanediol fermentation
    • Cheng K.K., Liu H.J., Liu D.H. Multiple growth inhibition of Klebsiella pneumoniae in 1,3-propanediol fermentation. Biotechnol. Lett., 2005; 27, 19-22.
    • (2005) Biotechnol. Lett. , vol.27 , pp. 19-22
    • Cheng, K.K.1    Liu, H.J.2    Liu, D.H.3
  • 9
    • 0032450012 scopus 로고    scopus 로고
    • 12-dependent glycerol and diol dehydratases and organization of the encoding genes
    • DOI 10.1016/S0168-6445(98)00021-7, PII S0168644598000217
    • Daniel R, Bobik TA, Gottschalk G. Biochemistry of coenzyme B12-dependent glycerol and diol dehydratases and organization of the encoding genes. FEMS Microbiol Rev. 1998; 22(5), 553-66. (Pubitemid 29074353)
    • (1998) FEMS Microbiology Reviews , vol.22 , Issue.5 , pp. 553-566
    • Daniel, R.1    Bobik, T.A.2    Gottschalk, G.3
  • 10
    • 0031877248 scopus 로고    scopus 로고
    • Cofactor engineering: A novel approach to metabolic engineering in Lactococcus lactis by controlled expression of NADH oxidase
    • Felipe F.L.d., Kleerebezem M., Vos W.M.d., Hugenholtz J. Cofactor engineering: a novel approach to metabolic engineering in Lactococcus lactis by controlled expression of NADH oxidase. J. Bacteriol., 1998; 180, 3804-8. (Pubitemid 28361574)
    • (1998) Journal of Bacteriology , vol.180 , Issue.15 , pp. 3804-3808
    • De Felipe, F.L.1    Kleerebezem, M.2    De Vos, W.M.3    Hugenholtz, J.4
  • 11
    • 0020045410 scopus 로고
    • 12-dependent glycerol and diol dehydratases
    • Forage R. G., and Foster M.A. Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases. J. Bacteriol. 1982; 149, 413-9. (Pubitemid 12106663)
    • (1982) Journal of Bacteriology , vol.149 , Issue.2 , pp. 413-419
    • Forage, R.G.1    Foster, M.A.2
  • 12
    • 0020463437 scopus 로고
    • Dha System mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418
    • Forage R. G., and Lin E. C. C. dha system mediating aerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418. J. Bacteriol., 1982; 151, 591-9. (Pubitemid 13230450)
    • (1982) Journal of Bacteriology , vol.151 , Issue.2 , pp. 591-599
    • Forage, R.G.1    Lin, E.C.C.2
  • 13
    • 29044445995 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol
    • DOI 10.1016/j.ymben.2005.06.001, PII S1096717605000509
    • González-Pajuelo M., Meynial-Salles I., Mendes F., Andrade J.C., Vasconcelos I. Soucaille P. Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. Metabol. Eng., 2005; 7, 329-36. (Pubitemid 41790465)
    • (2005) Metabolic Engineering , vol.7 , Issue.5-6 , pp. 329-336
    • Gonzalez-Pajuelo, M.1    Meynial-Salles, I.2    Mendes, F.3    Andrade, J.C.4    Vasconcelos, I.5    Soucaille, P.6
  • 14
    • 33644858397 scopus 로고    scopus 로고
    • Microbial conversion of Glycerol to 1,3-Propanediol : Physiological Comparison of a Natural Producer, Clostridium butyricum VPI 3266, and an Engineered Strain, Clostridium acetobutylicum DG1(pSPD5
    • González-Pajuelo M., Meynial-Salles I., Mendes F., Soucaille P., Vasconcelos I. Microbial conversion of Glycerol to 1,3-Propanediol : Physiological Comparison of a Natural Producer, Clostridium butyricum VPI 3266, and an Engineered Strain, Clostridium acetobutylicum DG1(pSPD5). Appl. Env. Microbiol., 2006; 72, 96-101.
    • (2006) Appl. Env. Microbiol. , vol.72 , pp. 96-101
    • González-Pajuelo, M.1    Meynial-Salles, I.2    Mendes, F.3    Soucaille, P.4    Vasconcelos, I.5
  • 16
    • 0035140627 scopus 로고    scopus 로고
    • Fnr is required for NifL-dependent oxygen control of nif gene expression in Klebsiella pneumoniae
    • DOI 10.1128/JB.183.4.1385-1393.2001
    • Grabbe R, Klopprogge K, Schmitz RA. FNR is required for NifL-dependent oxygen control of nif gene expression in Klebsiella pneumoniae. J Bacteriol, 2001b; 183, 1385-93. (Pubitemid 32107735)
    • (2001) Journal of Bacteriology , vol.183 , Issue.4 , pp. 1385-1393
    • Grabbe, R.1    Klopprogge, K.2    Schmitz, R.A.3
  • 17
    • 48349134931 scopus 로고    scopus 로고
    • Isolation and characterization of microorganisms able to produce 1,3-propanediol under aerobic conditions
    • Hao J., Lin R., Zheng Z., Liu H., Liu D. Isolation and characterization of microorganisms able to produce 1,3-propanediol under aerobic conditions. World J Microbiol Biotechnol., 2008a; 24, 1731-40.
    • (2008) World J Microbiol Biotechnol. , vol.24 , pp. 1731-1740
    • Hao, J.1    Lin, R.2    Zheng, Z.3    Liu, H.4    Liu, D.5
  • 18
    • 46949102327 scopus 로고    scopus 로고
    • Decrease of 3-hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae TUAC01
    • Hao J., Wang W., Tian J., Li J., Liu D. Decrease of 3- hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae TUAC01. J. Ind. Microbiol. Biotechnol., 2008b; 35, 735-41.
    • (2008) J. Ind. Microbiol. Biotechnol. , vol.35 , pp. 735-741
    • Hao, J.1    Wang, W.2    Tian, J.3    Li, J.4    Liu, D.5
  • 19
    • 77954689166 scopus 로고    scopus 로고
    • Soo PC Inactivation of dhaD and dhaK abolishes by-product accumulation during 1,3-propanediol production in Klebsiella pneumoniae
    • Horng YT, Chang KC, Chou TC, Yu CJ, Chien CC, Wei YH, Soo PC Inactivation of dhaD and dhaK abolishes by-product accumulation during 1,3-propanediol production in Klebsiella pneumoniae. J Ind Microbiol Biotechnol. 2010; 37(7), 707-16.
    • (2010) J Ind Microbiol Biotechnol. , vol.37 , Issue.7 , pp. 707-716
    • Horng, Y.T.1    Chang, K.C.2    Chou, T.C.3    Yu, C.J.4    Chien, C.C.5    Wei, Y.H.6
  • 20
    • 0023215805 scopus 로고
    • Klebsiella pneumoniae 1,3-propanediol:NAD+ oxidoreductase
    • Johnson E.A., Lin E.C. Klebsiella pneumoniae 1,3-propanediol:NAD+ oxidoreductase. J. Bacetriol., 1987; 169, 2050-4.
    • (1987) J. Bacetriol. , vol.169 , pp. 2050-2054
    • Johnson, E.A.1    Lin, E.C.2
  • 21
    • 35448951368 scopus 로고    scopus 로고
    • Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases
    • DOI 10.1111/j.1742-4658.2007.06074.x
    • Kajiura H., Mori K., Shibata N., Toraya T. Molecular basis for specifcities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases. FEBS J., 2007; 274, 5556-66. (Pubitemid 47622067)
    • (2007) FEBS Journal , vol.274 , Issue.21 , pp. 5556-5566
    • Kajiura, H.1    Mori, K.2    Shibata, N.3    Toraya, T.4
  • 23
    • 57949100798 scopus 로고    scopus 로고
    • Enhanced activity of yqhD oxidoreductase in synthesis of 1,3-propanediol by error-prone PCR
    • Li H., Chen J., Li Y. Enhanced activity of yqhD oxidoreductase in synthesis of 1,3-propanediol by error-prone PCR. Prog. Nat. Sci., 2008; 18, 1519-24.
    • (2008) Prog. Nat. Sci. , vol.18 , pp. 1519-1524
    • Li, H.1    Chen, J.2    Li, Y.3
  • 24
    • 34447117696 scopus 로고    scopus 로고
    • Microbial production of 1,3-propanediol from glycerol by Klebsiella pneumoniae under micro-aerobic conditions up to a pilot scale
    • DOI 10.1007/s10529-007-9398-2
    • Liu HJ, Zhang DJ, Xu YH, Mu Y, Sun YQ, Xiu ZL. Microbial production of 1,3-propanediol from glycerol by Klebsiella pneumoniae under micro-aerobic conditions up to a pilot scale. Biotechnol Lett. 2007; 29(8), 1281-5. (Pubitemid 47035031)
    • (2007) Biotechnology Letters , vol.29 , Issue.8 , pp. 1281-1285
    • Liu, H.-J.1    Zhang, D.-J.2    Xu, Y.-H.3    Mu, Y.4    Sun, Y.-Q.5    Xiu, Z.-L.6
  • 25
    • 82755183873 scopus 로고    scopus 로고
    • Stimulation of reductive glycerol metabolism by overexpression of an aldehyde dehydrogenase in a recombinant Klebsiella pneumoniae strain defective in the oxidative pathway
    • Epub ahead of print
    • Luo LH, Seo JW, Oh BR, Seo PS, Heo SY, Hong WK, Kim DH, Kim CH. Stimulation of reductive glycerol metabolism by overexpression of an aldehyde dehydrogenase in a recombinant Klebsiella pneumoniae strain defective in the oxidative pathway. J Ind Microbiol Biotechnol. 2010 Epub ahead of print.
    • (2010) J Ind Microbiol Biotechnol.
    • Luo, L.H.1    Seo, J.W.2    Oh, B.R.3    Seo, P.S.4    Heo, S.Y.5    Hong, W.K.6    Kim, D.H.7    Kim, C.H.8
  • 26
    • 77950461136 scopus 로고    scopus 로고
    • Relaxing the coenzyme specifcity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design
    • Ma C, Zhang L, Dai J, Xiu Z. Relaxing the coenzyme specifcity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design. J Biotechnol. 2010; 146(4), 173-8.
    • (2010) J Biotechnol , vol.146 , Issue.4 , pp. 173-178
    • Ma, C.1    Zhang, L.2    Dai, J.3    Xiu, Z.4
  • 27
    • 18144403554 scopus 로고    scopus 로고
    • Improving enzyme properties: When are closer mutations better?
    • DOI 10.1016/j.tibtech.2005.03.005
    • Morley KL, Kazlauskas RJ. Improving enzyme properties: when are closer mutations better? Trends Biotechnol. 2005; 23(5), 231-7. (Pubitemid 40615535)
    • (2005) Trends in Biotechnology , vol.23 , Issue.5 , pp. 231-237
    • Morley, K.L.1    Kazlauskas, R.J.2
  • 28
    • 0142027026 scopus 로고    scopus 로고
    • Metabolic engineering for the microbial production of 1,3-propanediol
    • DOI 10.1016/j.copbio.2003.08.005
    • Nakamura C., Whited G. Metabolic engineering for the microbial production of 1,3-propanediol. Curr. Opin. Biotechnol., 2003; 14, 454-9. (Pubitemid 37298028)
    • (2003) Current Opinion in Biotechnology , vol.14 , Issue.5 , pp. 454-459
    • Nakamura, C.E.1    Whited, G.M.2
  • 29
    • 40749157124 scopus 로고    scopus 로고
    • Development of a new bioprocess for production of 1,3-propanediol I.: Modeling of glycerol bioconversion to 1,3-propanediol with Klebsiella pneumoniae enzymes
    • DOI 10.1007/s12010-007-0040-5
    • Németh Á., Sevella B. Development of a new Bioprocess for Production of 1,3-propanediol I: Modeling of Glycerol Bioconversion to 1,3-propanediol with Klebsiella pneumoniae Enzymes. Appl. Biochem. Biotechnol., 2008; 144, 47-58. (Pubitemid 351378026)
    • (2008) Applied Biochemistry and Biotechnology , vol.144 , Issue.1 , pp. 47-58
    • Nemeth, A.1    Sevella, B.2
  • 30
    • 43149093576 scopus 로고    scopus 로고
    • Escherichia coli YqhD exhibits aldehyde reductase activity and protects from the harmful efect of lipid peroxidation-derived aldehydes
    • Pérez JM, Arenas FA, Pradenas GA, Sandoval JM, Vásquez CC. Escherichia coli YqhD exhibits aldehyde reductase activity and protects from the harmful efect of lipid peroxidation-derived aldehydes. J Biol Chem. 2008; 283(12), 7346-53.
    • (2008) J Biol Chem , vol.283 , Issue.12 , pp. 7346-7353
    • Pérez, J.M.1    Arenas, F.A.2    Pradenas, G.A.3    Sandoval, J.M.4    Vásquez, C.C.5
  • 31
    • 70350214184 scopus 로고    scopus 로고
    • Saturation-mutagenesis in two positions distant from active site of a Klebsiella pneumoniae glycerol dehydratase identifes some highly active mutants
    • Qi X, Chen Y Jiang K, Zuo W, Luo Z, Wei Y, Du L, Wei H, Huang R, Du Q. Saturation-mutagenesis in two positions distant from active site of a Klebsiella pneumoniae glycerol dehydratase identifes some highly active mutants. J Biotechnol. 2009; 144(1), 43-50.
    • (2009) J Biotechnol , vol.144 , Issue.1 , pp. 43-50
    • Qi, X.1    Chen, Y.2    Jiang, K.3    Zuo, W.4    Luo, Z.5    Wei, Y.6    Du, L.7    Wei, H.8    Du Huang, R.Q.9
  • 33
    • 70349985735 scopus 로고    scopus 로고
    • Microbial production of 1,3-propanediol: Recent developments and emerging opportunities
    • Saxena R.K., Anand P, Saran S., Isar J. Microbial production of 1,3-propanediol: Recent developments and emerging opportunities. Biotechnol. Adv., 2009; 27, 895-913.
    • (2009) Biotechnol. Adv. , vol.27 , pp. 895-913
    • Saxena, R.K.1    Anand, P.2    Saran, S.3    Isar, J.4
  • 35
    • 69249222950 scopus 로고    scopus 로고
    • Elimination of by-product formation during production of 1,3-propanediol in Klebsiella pneumoniae by inactivation of glycerol oxidative pathway
    • Seo M.Y., Seo J.W., Heo S.Y., Baek J.O., Rairakhwada D., Oh B.R., Seo P.S., Choi M.H., Kim C.H. Elimination of by-product formation during production of 1,3-propanediol in Klebsiella pneumoniae by inactivation of glycerol oxidative pathway. Appl. Microbiol. Biotechnol., 2009; 84, 527-34.
    • (2009) Appl. Microbiol. Biotechnol. , vol.84 , pp. 527-534
    • Seo, M.Y.1    Seo, J.W.2    Heo, S.Y.3    Baek, J.O.4    Rairakhwada, D.5    Oh, B.R.6    Seo, P.S.7    Choi, M.H.8    Kim, C.H.9
  • 36
    • 0031985450 scopus 로고    scopus 로고
    • Construction and characterization of a 1, 3-Propanediol Operon
    • Skraly F.A., Lytle B.L., Cameron D.C. Construction and characterization of a 1,3-Propanediol Operon. Appl. Environ. Microbiol., 1998; 64, 98-105.
    • (1998) Appl. Environ. Microbiol. , vol.64 , pp. 98-105
    • Skraly, F.A.1    Lytle, B.L.2    Cameron, D.C.3
  • 37
    • 0037360376 scopus 로고    scopus 로고
    • Comparative genomic analysis of dha regulon and related genes for anaerobic glycerol metabolism in bacteria
    • DOI 10.1021/bp025739m
    • Sun J, van den Heuvel J, Soucaille P, Qu Y, Zeng AP. Comparative genomic analysis of dha regulon and related genes for anaerobic glycerol metabolism in bacteria. Biotechnol Prog. 2003; 19(2), 263-72. (Pubitemid 36420971)
    • (2003) Biotechnology Progress , vol.19 , Issue.2 , pp. 263-272
    • Sun, J.1    Van Den Heuvel, J.2    Soucaille, P.3    Qu, Y.4    Zeng, A.-P.5
  • 38
    • 36749093014 scopus 로고    scopus 로고
    • Mathematical modeling of glycerol fermentation by Klebsiella pneumoniae: Concerning enzyme-catalytic reductive pathway and transport of glycerol and 1,3-propanediol across cell membrane
    • DOI 10.1016/j.bej.2007.06.002, PII S1369703X07002227
    • Sun Y.Q., Qi W.T., Teng H., Xiu Z.L., Zeng A.P. Mathematical modeling of glycerol fermentation by Klebsiella pneumoniae: Concerning enzyme-catalytic reductive pathway and transport of glycerol and 1,3-propanediol across cell membrane. Biochem. Eng. J., 2008; 38, 22-32. (Pubitemid 350216533)
    • (2008) Biochemical Engineering Journal , vol.38 , Issue.1 , pp. 22-32
    • Sun, Y.Q.1    Qi, W.T.2    Teng, H.3    Xiu, Z.L.4    Zeng, A.P.5
  • 39
    • 0033872063 scopus 로고    scopus 로고
    • Specificities of reactivating factors for adenosylcobalamin-dependent diol dehydratase and glycerol dehydratase
    • DOI 10.1007/s002030000179
    • Tobimatsu T., Kajiura H., Toraya T. Specifcities of reactivating factors for adenosylcobalamin-dependent diol dehydratase and glycerol dehydratase. Arch. Microbiol., 2000; 174, 81-8. (Pubitemid 30625684)
    • (2000) Archives of Microbiology , vol.174 , Issue.1-2 , pp. 81-88
    • Tobimatsu, T.1    Kajiura, H.2    Toraya, T.3
  • 40
    • 0006412028 scopus 로고
    • Enhancement of 1,3-propanediol production by cofermentation in Escherichia coli expressing Klebsiella pneumoniae dha regulon genes
    • Tong I.T., Cameron D.C. Enhancement of 1,3-propanediol production by cofermentation in Escherichia coli expressing Klebsiella pneumoniae dha regulon genes. Appl. Biochem. Biotechnol., 1992; 34-35, 149-59.
    • (1992) Appl. Biochem. Biotechnol. , vol.34-35 , pp. 149-159
    • Tong, I.T.1    Cameron, D.C.2
  • 41
    • 0025786724 scopus 로고
    • 1,3-Propanediol production by Escherichia coli expressing genes from the Klebsiella pneumoniae dha regulon
    • Tong I.T., Liao H.H., Cameron D.C. 1,3-Propanediol production by Escherichia coli expressing genes from the Klebsiella pneumoniae dha regulon. Appl. Environ. Microbiol., 1991; 57, 3541-6.
    • (1991) Appl. Environ. Microbiol. , vol.57 , pp. 3541-3546
    • Tong, I.T.1    Liao, H.H.2    Cameron, D.C.3
  • 42
    • 0017626312 scopus 로고
    • Studies on the mechanism of the adenosylcobalamin dependent diol dehydrase reaction by the use of analogs of the coenzyme
    • Toraya T, Ushio K, Fukui S, Hogenkamp PC. Studies on the mechanism of the adenosylcobalamin-dependent diol dehydrase reaction by the use of analogs of the coenzyme. J Biol Chem. 1977; 252(3), 963-70. (Pubitemid 8041890)
    • (1977) Journal of Biological Chemistry , vol.252 , Issue.3 , pp. 963-970
    • Toraya, T.1    Ushio, K.2    Fukui, S.3    Hogenkamp, H.P.C.4
  • 43
    • 0019332492 scopus 로고
    • The synthesis of several immobilized derivatives of vitamin B12 coenzyme and their use as afnity adsorbents for a study of interactions of diol dehydrase with the coenzyme
    • Toraya T, Fukui S. The synthesis of several immobilized derivatives of vitamin B12 coenzyme and their use as afnity adsorbents for a study of interactions of diol dehydrase with the coenzyme. J Biol Chem. 1980; 255(8), 3520-5.
    • (1980) J Biol Chem , vol.255 , Issue.8 , pp. 3520-3525
    • Toraya, T.1    Fukui, S.2
  • 44
    • 0021099840 scopus 로고
    • Ligand exchange reactions of diol dehydrase-bound cobalamins and the efect of the nucleoside binding
    • Toraya T, Watanabe N, Ushio K, Matsumoto T, Fukui S. Ligand exchange reactions of diol dehydrase-bound cobalamins and the efect of the nucleoside binding. J Biol Chem. 1983; 258(15), 9296-301.
    • (1983) J Biol Chem , vol.258 , Issue.15 , pp. 9296-9301
    • Toraya, T.1    Watanabe, N.2    Ushio, K.3    Matsumoto, T.4    Fukui, S.5
  • 45
    • 0023019237 scopus 로고
    • The synthesis of adenine-modified analogs of adenosylcobalamin and their coenzymic function in the reaction catalyzed by diol dehydrase
    • Toraya T, Matsumoto T, Ichikawa M, Itoh T, Sugawara T, Mizuno Y. The synthesis of adenine-modifed analogs of adenosylcobalamin and their coenzymic function in the reaction catalyzed by diol dehydrase. J Biol Chem. 1986; 261(20), 9289-93. (Pubitemid 17218207)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.20 , pp. 9289-9293
    • Toraya, T.1    Matsumoto, T.2    Ichikawa, M.3
  • 46
    • 0023664559 scopus 로고
    • Activation and cleavage of the carbon-cobalt bond of adeninylethylcobalamin by diol dehydrase
    • Toraya T, Watanabe N, Ichikawa M, Matsumoto T, Ushio K, Fukui S. Activation and cleavage of the carbon-cobalt bond of adeninylethylcobalamin by diol dehydrase. J Biol Chem. 1987; 262(18), 8544-50.
    • (1987) J Biol Chem. , vol.262 , Issue.18 , pp. 8544-8550
    • Toraya, T.1    Watanabe, N.2    Ichikawa, M.3    Matsumoto, T.4    Ushio, K.5    Fukui, S.6
  • 47
    • 65249177164 scopus 로고    scopus 로고
    • Directed enzyme evolution: Climbing ftness peaks one amino acid at a time
    • Tracewell CA, Arnold FH. Directed enzyme evolution: climbing ftness peaks one amino acid at a time. Curr Opin Chem Biol. 2009; 13(1), 3-9.
    • (2009) Curr Opin Chem Biol , vol.13 , Issue.1 , pp. 3-9
    • Tracewell, C.A.1    Arnold, F.H.2
  • 48
    • 3342911436 scopus 로고    scopus 로고
    • Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling
    • DOI 10.1016/j.chembiol.2004.04.019, PII S1074552104001681
    • van Loo B, Spelberg JH, Kingma J, Sonke T, Wubbolts MG, Janssen DB. Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shufing. Chem Biol. 2004; 11(7), 981-90. (Pubitemid 38991792)
    • (2004) Chemistry and Biology , vol.11 , Issue.7 , pp. 981-990
    • Van Loo, B.1    Spelberg, J.H.L.2    Kingma, J.3    Sonke, T.4    Wubbolts, M.G.5    Janssen, D.B.6
  • 49
    • 1642386688 scopus 로고    scopus 로고
    • 3-Hydroxypropionaldehyde: Applications and perspectives of biotechnological production
    • DOI 10.1007/s00253-003-1497-y
    • Vollenweider S., Lacroix C. 3-Hydroxypropionaldehyde: applications and perspectives of biotechnological production. Appl. Microbiol. Biotechnol., 2004; 64, 16-27. (Pubitemid 38396789)
    • (2004) Applied Microbiology and Biotechnology , vol.64 , Issue.1 , pp. 16-27
    • Vollenweider, S.1    Lacroix, C.2
  • 50
    • 0014027350 scopus 로고
    • Studies on the mechanism of action of cobalamine coenzymes. Chemical properties of the enzyme-coenzyme complex
    • Wagner O.W., Lee H.A. Jr., Frey P.A., Abeles R.H. Studies on the mechanism of action of cobalamine coenzymes. Chemical properties of the enzyme-coenzyme complex. J. Biol. Chem., 1966; 241, 1751-62.
    • (1966) J. Biol. Chem. , vol.241 , pp. 1751-1762
    • Wagner, O.W.1    Lee Jr., H.A.2    Frey, P.A.3    Abeles, R.H.4
  • 51
    • 0042367748 scopus 로고    scopus 로고
    • Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniae
    • DOI 10.1002/bit.10701
    • Wang W., Sun J., Hartlep M., Deckwer D.W., Zeng A.P. Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniae. Biotechnol. Bioeng., 2003; 83, 525-36. (Pubitemid 36903746)
    • (2003) Biotechnology and Bioengineering , vol.83 , Issue.5 , pp. 525-536
    • Wang, W.1    Sun, J.2    Hartlep, M.3    Deckwer, W.-D.4    Zeng, A.-P.5
  • 52
    • 43349107589 scopus 로고    scopus 로고
    • Present state and perspective of downstream processing of biologically produced 1,3-propanediol and 2,3-butanediol
    • Xiu ZL, Zeng AP. Present state and perspective of downstream processing of biologically produced 1,3-propanediol and 2,3-butanediol. Appl Microbiol Biotechnol. 2008; 78(6), 917-26.
    • (2008) Appl Microbiol Biotechnol. , vol.78 , Issue.6 , pp. 917-926
    • Xiu, Z.L.1    Zeng, A.P.2
  • 53
    • 70350532561 scopus 로고    scopus 로고
    • Metabolism in 1,3-Propanediol Fed-Batch Fermentation by a D-Lactate Defcient Mutant of Klebsiella pneumoniae
    • Xu Y.Z., Guo N.N., Zheng Z.M., Ou X.J., Liu H.J., Liu D.H. Metabolism in 1,3-Propanediol Fed-Batch Fermentation by a D-Lactate Defcient Mutant of Klebsiella pneumoniae. Biotechnol. Bioeng., 2009a; 104, 965-72.
    • (2009) Biotechnol. Bioeng. , vol.104 , pp. 965-972
    • Xu, Y.Z.1    Guo, N.N.2    Zheng, Z.M.3    Ou, X.J.4    Liu, H.J.5    Liu, D.H.6
  • 54
    • 57649086169 scopus 로고    scopus 로고
    • Quantitative analysis on inactivation and reactivation of recombinant glycerol dehydratase from Klebsiella pneumoniae XJPD-Li
    • Xu X.L., Zhang G.L., Wang L.W., Ma B.B., Li Ch. Quantitative analysis on inactivation and reactivation of recombinant glycerol dehydratase from Klebsiella pneumoniae XJPD-Li. J. Mol. Catal. B: Enzym., 2009b; 56, 108-14.
    • (2009) J. Mol. Catal. B: Enzym. , vol.56 , pp. 108-114
    • Xu, X.L.1    Zhang, G.L.2    Wang, L.W.3    Ma, B.B.4    Ch, L.5
  • 55
    • 33845782917 scopus 로고    scopus 로고
    • Fermentation of 1,3-propanediol by a lactate deficient mutant of Klebsiella oxytoca under microaerobic conditions
    • DOI 10.1007/s00253-006-0563-7
    • Yang G., Tian J., Li J. Fermentation of 1,3-propanediol by a lactate defcient mutant of Klebsiella oxytoca under microaerobic conditions. Appl. Microbiol. Biotechnol., 2007; 73, 1017-24. (Pubitemid 44974308)
    • (2007) Applied Microbiology and Biotechnology , vol.73 , Issue.5 , pp. 1017-1024
    • Yang, G.1    Tian, J.2    Li, J.3
  • 56
    • 0036360494 scopus 로고    scopus 로고
    • Bulk chemicals from biotechnology: The case of 1,3-propanediol production and the new trends
    • Zeng AP., Biebl H. Bulk chemicals from biotechnology: the case of 1,3-propanediol production and the new trends. Adv. Biochem. Eng. Biotechnol., 2002; 74, 239-59.
    • (2002) Adv. Biochem. Eng. Biotechnol. , vol.74 , pp. 239-259
    • Zeng, A.P.1    Biebl, H.2
  • 57
    • 0027657292 scopus 로고
    • Pathway analysis of glycerol fermentation by Klebsiella pneumoniae: Regulation of reducing equivalent balance and product formation
    • DOI 10.1016/0141-0229(93)90008-P
    • Zeng AP, Biebl H, Schlieker H, Deckwer WD. Pathway analysis of glycerol fermentation by Klebsiella pneumoniae: regulation of reducing equivalent balance and product formation. Enzyme Microbiol Technol 1993, 15, 770-779. (Pubitemid 23257954)
    • (1993) Enzyme and Microbial Technology , vol.15 , Issue.9 , pp. 770-779
    • Zeng, A.-P.1    Biebl, H.2    Schlieker, H.3    Deckwer, W.-D.4
  • 58
    • 0028485952 scopus 로고
    • Multiple product inhibition and growth modeling of Clostridium butyricum and Klebsiella pneumoniae in glycerol fermentation
    • DOI 10.1002/bit.260440806
    • Zeng AP, Ross A, Biebl H, Tag C, Günzel B, Deckwer WD. Multiple product inhibition and growth modeling of Clostridium butyricum and Klebsiella pneumoniae in glycerol fermentation. Biotechnol Bioeng. 1994; 44(8), 902-11. (Pubitemid 24308538)
    • (1994) Biotechnology and Bioengineering , vol.44 , Issue.8 , pp. 902-911
    • Zeng, A.-P.1    Ross, A.2    Biebl, H.3    Tag, C.4    Gunzel, B.5    Deckwer, W.D.6
  • 59
    • 60849096352 scopus 로고    scopus 로고
    • Introduction of an NADH regeneration system into Klebsiella oxytoca leads to an enhanced oxidative and reductive metabolism of glycerol
    • Zhang Y, Huang Z., Du C., Li Y, Cao Z. Introduction of an NADH regeneration system into Klebsiella oxytoca leads to an enhanced oxidative and reductive metabolism of glycerol. Metab. Eng., 2009; 11, 101-6.
    • (2009) Metab. Eng. , vol.11 , pp. 101-106
    • Zhang, Y.1    Huang, Z.2    Du, C.3    Li, Y.4    Cao, Z.5
  • 60
    • 33749436573 scopus 로고    scopus 로고
    • Inactivation of aldehyde dehydrogenase: A key factor for engineering 1,3-propanediol production by Klebsiella pneumoniae
    • DOI 10.1016/j.ymben.2006.05.008, PII S1096717606000450
    • Zhang Y., Li Y., Du C., Liu M., Cao Z. Inactivation of aldehyde dehydrogenase: a key factor for engineering 1,3-propanediol production by Klebsiella pneumoniae. Metab Eng., 2006; 8, 578-86. (Pubitemid 44512160)
    • (2006) Metabolic Engineering , vol.8 , Issue.6 , pp. 578-586
    • Zhang, Y.1    Li, Y.2    Du, C.3    Liu, M.4    Cao, Z.5
  • 61
    • 38349098217 scopus 로고    scopus 로고
    • Metabolic fux and robustness analysis of glycerol metabolism in Klebsiella pneumoniae
    • Zhang Q., Teng H., Sun Y., Xiu Z., Zeng AP. Metabolic fux and robustness analysis of glycerol metabolism in Klebsiella pneumoniae. Bioprocess Biosyst. Eng., 2008; 31, 127-35.
    • (2008) Bioprocess Biosyst. Eng. , vol.31 , pp. 127-135
    • Zhang, Q.1    Teng, H.2    Sun, Y.3    Xiu, Z.4    Zeng, A.P.5
  • 62
    • 64549118750 scopus 로고    scopus 로고
    • Metabolic pathway analysis of glycerol metabolism in Klebsiella pneumoniae incorporating oxygen regulatory system
    • Zhang Q, Xiu Z. Metabolic pathway analysis of glycerol metabolism in Klebsiella pneumoniae incorporating oxygen regulatory system. Biotechnol Prog. 2009;25(1), 103-15.
    • (2009) Biotechnol Prog , vol.25 , Issue.1 , pp. 103-115
    • Zhang, Q.1    Xiu, Z.2
  • 63
    • 62949246266 scopus 로고    scopus 로고
    • Efects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by Klebsiella pneumoniae under micro-aerobic conditions
    • Zhao L, Zheng Y Ma X, Wei D. Efects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by Klebsiella pneumoniae under micro-aerobic conditions. Bioprocess Biosyst Eng. 2009;32(3), 313-20.
    • (2009) Bioprocess Biosyst Eng , vol.32 , Issue.3 , pp. 313-320
    • Zhao, L.1    Zheng, Y.2    Ma, X.3    Wei, D.4
  • 64
    • 1342288664 scopus 로고    scopus 로고
    • Cloning and sequence analysis of the dhaT gene of the 1,3-propanediol regulon from Klebsiella pneumoniae
    • Zheng Y Cao Y Fang B. Cloning and sequence analysis of the dhaT gene of the 1,3-propanediol regulon from Klebsiella pneumoniae. Biotechnol Lett. 2004; 26(3), 251-5.
    • (2004) Biotechnol Lett. , vol.26 , Issue.3 , pp. 251-255
    • Zheng, Y.1    Cao, Y.2    Fang, B.3
  • 65
    • 33748536363 scopus 로고    scopus 로고
    • Overexpression of genes of the dha regulon and its effects on cell growth, glycerol fermentation to 1,3-propanediol and plasmid stability in Klebsiella pneumoniae
    • DOI 10.1016/j.procbio.2006.06.012, PII S1359511306002479, From Biochemcal Engineering to Systems Biology in Honour of Dr. Wolf-Dieter Deckwer
    • Zheng P., Wereath K., Sun J., Van den Heuvel J., Zeng, AP. Overexpression of genes of the dha regulon and its efects on cell growth, glycerol fermentation to 1,3-propanediol and plasmid stability in Klebsiella pneumoniae. Process Biochem., 2006; 41, 2160-9. (Pubitemid 44374383)
    • (2006) Process Biochemistry , vol.41 , Issue.10 , pp. 2160-2169
    • Zheng, P.1    Wereath, K.2    Sun, J.3    Van Den Heuvel, J.4    Zeng, A.-P.5
  • 66
    • 67649208907 scopus 로고    scopus 로고
    • Enhanced 1,3-propanediol production in recombinant Klebsiella pneumoniae carrying the gene yqhD encoding 1,3-propanediol oxidoreductase isoenzyme
    • Zhu J.G., Li S., Ji X.J., Huang H., Hu N. Enhanced 1,3-propanediol production in recombinant Klebsiella pneumoniae carrying the gene yqhD encoding 1,3-propanediol oxidoreductase isoenzyme. W. J. Microbiol. Biotechnol., 2009; 25, 1217-23.
    • (2009) W. J. Microbiol. Biotechnol. , vol.25 , pp. 1217-1223
    • Zhu, J.G.1    Li, S.2    Ji, X.J.3    Huang, H.4    Hu, N.5
  • 67
    • 77955554753 scopus 로고    scopus 로고
    • Expression of 1,3-propanediol oxidoreductase and its isoenzyme in Klebsiella pneumoniae for bioconversion of glycerol into 1,3-propanediol
    • Zhuge B, Zhang C, Fang H, Zhuge J, Permaul K. Expression of 1,3-propanediol oxidoreductase and its isoenzyme in Klebsiella pneumoniae for bioconversion of glycerol into 1,3-propanediol. Appl Microbiol Biotechnol. 2010; 87(6), 2177-84.
    • (2010) Appl Microbiol Biotechnol , vol.87 , Issue.6 , pp. 2177-2184
    • Zhuge, B.1    Zhang, C.2    Fang, H.3    Zhuge, J.4    Permaul, K.5


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