Fermentation of 1,3-propanediol by a lactate deficient mutant of Klebsiella oxytoca under microaerobic conditions

Applied Microbiology and Biotechnology

Volumn 73, Issue 5, 2007, Pages 1017-1024

  Yang, Guang ^a   Tian, Jiesheng ^a   Li, Jilun ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BYPRODUCTS; ENZYMES; FERMENTATION; GENES; GLYCEROL; SUGAR (SUCROSE);

FERMENTATION EFFICIENCY; KLEBSIELLA OXYTOCA; LACTIC ACID; MICROAEROBIC CONDITIONS;

ALCOHOLS;

1,3 PROPANEDIOL; LACTATE DEHYDROGENASE; LACTIC ACID;

ALCOHOL; ANOXIC CONDITIONS; BACTERIUM; BIOENGINEERING; CARBOXYLIC ACID; ENZYME ACTIVITY; FERMENTATION; MUTATION; OXIC CONDITIONS; SUCROSE;

AEROBIC CAPACITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; FED BATCH FERMENTATION; KLEBSIELLA OXYTOCA; NONHUMAN; NUCLEOTIDE SEQUENCE; STATISTICAL SIGNIFICANCE; WILD TYPE;

AEROBIOSIS; ANAEROBIOSIS; BIOMASS; BLOTTING, SOUTHWESTERN; BUTYLENE GLYCOLS; CONJUGATION, GENETIC; DNA, BACTERIAL; FERMENTATION; GENE DELETION; GLYCEROL; KLEBSIELLA OXYTOCA; L-LACTATE DEHYDROGENASE; LACTIC ACID; MUTAGENESIS, INSERTIONAL; POLYMERASE CHAIN REACTION; PROPYLENE GLYCOLS; SUCROSE;

KLEBSIELLA OXYTOCA;

EID: 33845782917     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-006-0563-7     Document Type: Article

References (43)

1. Abbad-Andaloussi S, Amine J, Gerard P, Petitdemange H (1998) Effect of glucose on glycerol metabolism by Clostridium butyricum DSM 5431. J Appl Microbiol 84:515-522
2. Ahrens K, Menzel K, Zeng AP, Deckwer WD (1998) Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella Pneumoniae in anaerobic continuous culture: III enzymes and fluxes of glycerol dissimilation and 1,3-propanediol formation. Biotechnol Bioeng 59:544-552
3. Biebl H (1991) Glycerol fermentation to 1,3-propanediol by butyricum. Measurement of product inhibition by use of a pHauxostat. Appl Microbiol Biotechnol 35:701-705
4. Biebl H (2001) Fermentation of glycerol by Clostridium pasteurianum-batch and continuous culture studies. J Ind Microbiol Biotechnol 27:18-26
5. Biebl H, Marten S (1995) Fermentation of glycerol to 1,3-propanediol: use of cosubstrates. Appl Microbiol Biotechnol 44:15-19
6. Biebl H, Marten S, Hippe H, Deckwer WD (1992) Glycerol conversion to 1,3-propanediol by newly isolated Clostridia. Appl Microbiol Biotechnol 36:592-597
7. Biebl H, Zeng AP, Menzel K, Deckwer WD (1998) Fermentation of glycerol to 1,3-propanediol and 2,3-butanediol by Klebsiella pneumoniae. Appl Microbiol Biotechnol 50:24-29
8. Biebl H, Menzel K, Zeng AP, Deckwer WD (1999) Microbial production of 1,3-propanediol. Appl Microbiol Biotechnol 52:289-297
9. Boenigk R, Bowien S, Gottschalk G (1993) Fermentation of glycerol to 1,3-propanediol in continuous cultures of Citrobacter Freundii. Appl Microbiol Biotechnol 38:453-457
10. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
11. Cameron DC, Altaras NE, Hoffman ML, Shaw AJ (1998) Metabolic engineering of propanediol pathways. Biotechnol Prog 14:116-125
12. Chen X, Zhang DJ, Qi WT, Gao SJ, Xiu ZL, Xu P (2003) Microbial fed-batch production of 1,3-propanediol by Klebsiella pneumoniae under micro-aerobic conditions. Appl Microbiol Biotechnol 63:143-146
13. Cheng KK, Liu DH, Sun Y, Liu WB (2004) 1,3-propanediol production by Klebsiella pneumoniae under different aeration strategies. Biotechnol Lett 26:911-915
14. Cheng KK, Liu HJ, Liu DH (2005) Multiple growth inhibition of Klebsiella pneumoniae in 1,3-propanediol fermentation. Biotechnol Lett 27:19-22
15. Colin T, Bories A, Moulin G (2000) Inhibition of Clostridium butyricum by 1,3-propanediol and diols during glycerol fermentation. Appl Microbiol Biotechnol 54:201-205
16. Colin T, Bories A, Lavigne C, Moulin G (2001) Effects of acetate and butyrate during glycerol fermentation by Clostridium butyricum. Curr Microbiol 43:238-243
17. 3. Appl Microbiol Biotechnol 36:289-295
18. Homann T, Tag C, Biebl H, Deckwer WD (1990) Fermentation of glycerol to 1,3-propanediol by Klebsiella and Citrobacter strains. Appl Microbiol Biotechnol 33:121-126
19. Huang H, Gong CS, Tsao GT (2002) Production of 1,3-propanediol by Klebsiella pneumoniae. Appl Biochem Biotechnol 98-100:687-698
20. Menzel K, Zeng AP, Deckwer WD (1997) High concentration and productivity of 1,3-propanediol from continuous fermentation of glycerol by Klebsiella pneumoniae. Enzyme Microb Technol 20:82-86
21. Miller VL, Mekalanos JJ (1988) A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio Cholerae requires toxR. J Bacteriol 170:2575-2583
22. Nakamura CE, Whited GM (2003) Metabolic engineering for the microbial production of 1,3-propanediol. Curr Opin Biotechnol 14:454-459
23. Ohta K, Beall DS, Mejia JP, Shanmugam KT, Ingram LO (1991) Metabolic engineering of Klebsiella oxytoca M5A1 for ethanol production from xylose and glucose. Appl Environ Microbiol 157:2810-2815
24. Papanikolaou S, Ruiz-Sanchez P, Pariset B, Blanchard F, Fick M (2000) High production of 1,3-propanediol from industrial glycerol by a newly isolated Clostridium butyricum strain. J Biotechnol 77:191-208
25. Petitdemange E, Manginot-Durr C, Abbad-Andaloussi S, Raval G (1995) Fermentation of raw glycerol to 1,3-propanediol by new strains of Clostridium butyricum. J Ind Microbiol 15:498-501
26. Reimann A, Biebl H (1996) Production of 1,3-propanediol by Clostridium butyricum DSM 5431 and product tolerant mutants in fed-batch culture. Feeding strategy for glycerol and ammonium. Biotechnol Lett 18:827-832
27. Reimann A, Abbad-Andaloussi S, Biebl H, Petitdemange H (1998) 1,3-propanediol formation with product-tolerant mutants of Clostridium butyricum DSM 5431 in continuous culture: productivity, carbon and electron flow. J Appl Microbiol 84:1125-1130
28. Saint-Amans S, Soucaille P (1995) Carbon and electron flow in Clostridium butyricum grown in chemostat culture on glucoseglycerol mixtures. Biotechnol Lett 17:211-216
29. Saint-Amans S, Girbal L, Andrade J, Ahrens K, Soucaille P (2001) Regulation of carbon and flow in Clostridium butyricum VPI 3266 grown on glucose-glycerol mixtures. J Bacteriol 183(5):1748-1754
30. Skraly FA, Lytle BL, Cameron DC (1998) Construction and characterization of a 1,3-propanediol operon. Appl Environ Microbiol 64:98-105
31. Solomon BO, Zeng AP, Hibel H, Schlieker H, Posten C, Deckwer WD (1995) Comparison of the energetic efficiencies of hydrogen and oxychemicals formation in Klebsiella pneumoniae and Clostridium butyricum during anaerobic growth on glycerol. J Biotechnol 39:107-117
32. Sprenger GA, Hammer GA, Johnson EA, Lin ECC (1989) Anaerobic growth of Escherichia coli on glycerol by importing genes of the dha regulon from Klebsiella pneumoniae. J Gen Microbiol 135:1255-1262
33. Syu MJ (2001) Biological production of 2,3-butanediol. Appl Microbiol Biotechnol 55:10-18
34. Tarmy EM, Kaplan NO (1968) Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. J Biol Chem 271:2579-2586
35. Tong IT, Cameron DC (1992) Enhancement of 1,3-propanediol production by cofermentation in Escherichia coli expressing Klebsiella pneumoniaedha regulon genes. Appl Biochem Biotechnol 34-35:149-159
36. Tong IT, Liao HH, Cameron DC (1991) 1,3-propanediol production by Escherichia coli expressing genes from the Klebsiella pneumoniae dha regulon. Appl Environ Microbiol 57:3541-3546
37. Voloch M, Jansen NB, Ladisch MR, Tsao GT, Narayan R, Rodwell VW (1985) 2,3-Butanediol. In: Cooney CL, Humphrey AE (eds) Comprehensive biotechnology. Pergamon, Oxford, pp 933-947
38. Zeng AP (1996) Pathway and kinetic analysis of 1,3-propanediol production from glycerol fermentation by Clostridium butyricum. Bioprocess Biosyst Eng 14:169-175
39. Zeng AP, Biebl H (2002) Bulk chemicals from biotechnology: the case of 1,3-propanediol production and the new trends. Adv Biochem Eng Biotechnol 74:239-259
40. Zeng AP, Biebl H, Schlieker H, Decker WD (1993) Pathway analysis of glycerol fermentation by Klebsiella pneumoniae: regulation of reducing equivalent balance and product formation. Enzyme Microb Technol 15:770-779
41. Zeng AP, Ross A, Hibel H, Tag C, Günzel B, Decker WD (1994) Multiple product inhibition and growth modeling of Clostridium butyricum and Klebsiella pneumoniae in glycerol fermentation. Biotechnol Bioeng 44:902-911
42. Zhao DH, Li JL (2004) Construction and characterization of double mutants in nitrogenase of Klebsiella pneumoniae. Chin Sci Bull 49:1707-1713
43. Zhu MM, Lawman PD, Cameron DC (2002) Improving 1,3-propanediol production from glycerol in a metabolically engineered Escherichia coli by reducing accumulation of sn-glycerol-3-phosphate. Biotechnol Prog 18:694-699