Oxidative stress increases continuously with BMI and age with unfavourable profiles in males

Aging Male

Volumn 15, Issue 3, 2012, Pages 159-165

  Wonisch, Willibald ^a,b   Falk, Andreas ^c   Sundl, Isabella ^d   Winklhofer Roob, Brigitte M ^d   Lindschinger, Meinrad ^c  

^a Clinical Institute of Medical and Chemical Laboratory Diagnostics   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c Institute for Nutritional and Metabolic Diseases   (Austria)

^d UNIVERSITY OF GRAZ   (Austria)

Author keywords

Lipid peroxidation; Obesity; Reactive oxygen species

Indexed keywords

BILIRUBIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; PEROXIDE; URIC ACID;

ADULT; AGE; ANTIBODY TITER; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; FEMALE; HUMAN; LIPOPROTEIN BLOOD LEVEL; MALE; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; SEX DIFFERENCE; URIC ACID BLOOD LEVEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; AUTOANTIBODIES; BILIRUBIN; BODY MASS INDEX; CHOLESTEROL; HUMANS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; OXIDATIVE STRESS; RISK FACTORS; URIC ACID; YOUNG ADULT;

EID: 84864721258     PISSN: 13685538     EISSN: 14730790     Source Type: Journal    
DOI: 10.3109/13685538.2012.669436     Document Type: Article

References (46)

1. Grimble RF. Inflammatory response in the elderly. Curr Opin Clin Nutr Metab Care 2003;6:21-29.
2. Hopps E, Noto D, Caimi G, Averna MR. A novel component of the metabolic syndrome: The oxidative stress. Nutr Metab Cardiovasc Dis 2010;20:72-77.
3. Frohnert BI, Sinaiko AR, Serrot FJ, Foncea RE, Moran A, Ikramuddin S, Choudry U, Bernlohr DA. Increased adipose protein carbonylation in human obesity. Obesity (Silver Spring) 2011;19:1735-1741.
4. Keaney JFJr, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, Massaro JM, et al.; Framingham Study. Obesity and systemic oxidative stress: Clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 2003;23:434-439.
5. Serrano Rios M. Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus. Eur J Clin Invest 1998;28:S14-S17.
6. Ferrannini E, Camastra S. Relationship between impaired glucose tolerance, non-insulin-dependent diabetes mellitus in obesity. Eur J Clin Invest 1998;28:S3-S7.
7. Vincent HK, Innes KE, Vincent KR. Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity. Diabetes Obes Metab 2007;9:813-839.
8. Norris AL, Steinberger J, Steffen LM, Metzig AM, Schwarzenberg SJ, Kelly AS. Circulating oxidized LDL and inflammation in extreme pediatric obesity. Obesity (Silver Spring) 2011;19:1415-1419.
9. Urakawa H, Katsuki A, Sumida Y, Gabazza EC, Murashima S, Morioka K, Maruyama N, et al. Oxidative stress is associated with adiposity and insulin resistance in men. J Clin Endocrinol Metab 2003;88:4673-4676.
10. Montuschi P, Barnes PJ, Roberts LJ2nd. Isoprostanes: Markers and mediators of oxidative stress. FASEB J 2004;18:1791-1800.
11. Zarkovic N. 4-hydroxynonenal as a bioactive marker of pathophysiological processes. Mol Aspects Med 2003;24:281-291.
12. Spickett CM, Wiswedel I, Siems W, Zarkovic K, Zarkovic N. Advances in methods for the determination of biologically relevant lipid peroxidation products. Free Radic Res 2010;44:1172-1202.
13. Borovic S, Rabuzin F, Waeg G, Zarkovic N. Enzyme-linked immunosorbent assay for 4-hydroxynonenal-histidine conjugates. Free Radic Res 2006;40:809-820.
14. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128.
15. Prior RL, Cao G. In vivo total antioxidant capacity: Comparison of different analytical methods. Free Radic Biol Med 1999;27:1173-1181.
16. Rice-Evans C, Miller NJ. Total antioxidant status in plasma and body fluids. Meth Enzymol 1994;234:279-293.
17. Tatzber F, Griebenow S, Wonisch W, Winkler R. Dual method for the determination of peroxidase-activity and total peroxides - Iodide leads to a significant increase of peroxidase-activity in human sera. Anal Biochem 2003;316:147-153.
18. Tatzber F, Esterbauer H. Free Radicals IX: Autoantibodies to oxidized low density lipoprotein. London: Richelieu Press; 1995. pp 245-267.
19. Jankowska EW, Medras M, Rogucka EA. Body mass index, waist/hip ratio and androgen-estrogen activity in younger versus older Polish men. Aging Male 2000;3:177-184.
20. Mar Bibiloni M, Martínez E, Llull R, Maffiotte E, Riesco M, Llompart I, Pons A, Tur JA. Metabolic syndrome in adolescents in the Balearic Islands, a Mediterranean region. Nutr Metab Cardiovasc Dis 2011;21:446-454.
21. Bowry VW, Stanley KK, Stocker R. High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors. Proc Natl Acad Sci USA 1992;89:10316-10320.
22. Madhavan M, Wattigney WA, Srinivasan SR, Berenson GS. Serum bilirubin distribution and its relation to cardiovascular risk in children and young adults. Atherosclerosis 1997;131:107-113.
23. Wu TW, Fung KP, Yang CC. Unconjugated bilirubin inhibits the oxidation of human low density lipoprotein better than Trolox. Life Sci 1994;54:477-481.
24. Onat A, Can G, Ornek E, Cicek G, Ayhan E, Dogan Y. Serum gammaglutamyltransferase: Independent predictor of risk of diabetes, hypertension, metabolic syndrome, and coronary disease. Obesity (2 June) 2011. doi:10.1038/oby.2011.136.
25. Mikami T, Yoshino Y, Ito A. Does a relationship exist between the urate pool in the body and lipid peroxidation during exercise? Free Radic Res 2000;32:31-39.
26. Nieto FJ, Iribarren C, Gross MD, Comstock GW, Cutler RG. Uric acid and serum antioxidant capacity: A reaction to atherosclerosis? Atherosclerosis 2000;148:131-139.
27. Lindschinger M, Nadlinger K, Adelwöhrer N, Holweg K, Wögerbauer M, Birkmayer J, Smolle KH, Wonisch W. Oxidative stress: Potential of distinct peroxide determination systems. Clin Chem Lab Med 2004;42:907-914.
28. Stanger O, Semmelrock HJ, Wonisch W, Bös U, Pabst E, Wascher TC. Effects of folate treatment and homocysteine lowering on resistance vessel reactivity in atherosclerotic subjects. J Pharmacol Exp Ther 2002;303:158-162.
29. Lippi G, Montagnana M, Franchini M, Favaloro EJ, Targher G. The paradoxical relationship between serum uric acid and cardiovascular disease. Clin Chim Acta 2008;392:1-7.
30. Kuno T, Hozumi M, Morinobu T, Murata T, Mingci Z, Tamai H. Antioxidant vitamin levels in plasma and low density lipoproteins of obese girls. Free Radic Res 1998;28:81-86.
31. Sies H, Stahl W, Sevanian A. Nutritional, dietary and postprandial oxidative stress. J Nutr 2005;135:969-972.
32. Davì G, Guagnano MT, Ciabattoni G, Basili S, Falco A, Marinopiccoli M, Nutini M, et al. Platelet activation in obese women: Role of inflammation and oxidant stress. JAMA 2002;288:2008-2014.
33. Winklhofer-Roob BM, Meinitzer A, Maritschnegg M, Roob JM, Khoschsorur G, Ribalta J, Sundl I, et al.; VITAGE Study Group. Effects of vitamin E depletion/repletion on biomarkers of oxidative stress in healthy aging. Ann N Y Acad Sci 2004;1031:361-364.
34. Brown LA, Kerr CJ, Whiting P, Finer N, McEneny J, Ashton T. Oxidant stress in healthy normal-weight, overweight, and obese individuals. Obesity (Silver Spring) 2009;17:460-466.
35. Suzuki K, Ito Y, Ochiai J, Kusuhara Y, Hashimoto S, Tokudome S, Kojima M, et al.; JACC Study Group. Relationship between obesity and serum markers of oxidative stress and inflammation in Japanese. Asian Pac J Cancer Prev 2003;4:259-266.
36. Nikolic-Heitzler V, Rabuzin F, Tatzber F, Vrkic N, Bulj N, Borovic S, Wonisch W, et al. Persistent oxidative stress after myocardial infarction treated by percutaneous coronary intervention. Tohoku J Exp Med 2006;210:247-255.
37. Block G, Dietrich M, Norkus EP, Morrow JD, Hudes M, Caan B, Packer L. Factors associated with oxidative stress in human populations. Am J Epidemiol 2002;156:274-285.
38. Fukumoto M, Shoji T, Emoto M, Kawagishi T, Okuno Y, Nishizawa Y. Antibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population. Arterioscler Thromb Vasc Biol 2000;20:703-707.
39. Shoji T, Nishizawa Y, Fukumoto M, Shimamura K, Kimura J, Kanda H, Emoto M, et al. Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects. Atherosclerosis 2000;148:171-177.
40. Schippinger G, Fankhauser F, Abuja PA, Winklhofer-Roob BM, Nadlinger K, Halwachs-Baumann G, Wonisch W. Competetive and seasonal oxidative stress in elite alpine ski racers. Scand J Med Sci Sports 2009;19:206-212.
41. Chiesa R, Melissano G, Castellano R, Astore D, Marone EM, Grossi A, Maggi E, et al. In search of biological markers of high-risk carotid artery atherosclerotic plaque: Enhanced LDL oxidation. Ann Vasc Surg 1998;12:1-9.
42. Tinahones FJ, Gómez-Zumaquero JM, Garrido-Sánchez L, García-Fuentes E, Rojo-Martínez G, Esteva I, Ruiz de Adana MS, et al. Influence of age and sex on levels of anti-oxidized LDL antibodies and anti-LDL immune complexes in the general population. J Lipid Res 2005;46:452-457.
43. Cakatay U, Aydin S, Yanar K, Uzun H. Gender-dependent variations in systemic biomarkers of oxidative protein, DNA, and lipid damage in aged rats. Aging Male 2010;13:51-58.
44. Karolkiewicz J, Pilaczynska-Szczesniak L, Maciaszek J, Osinski W. Insulin resistance, oxidative stress markers and the blood antioxidant system in overweight elderly men. Aging Male 2006;9:159-163.
45. Sekhavat L, Moein MR. The effect of male body mass index on sperm parameters. Aging Male 2010;13:155-158.
46. Blumentals WA, Gomez-Caminero A, Joo S, Vannappagari V. Is erectile dysfunction predictive of peripheral vascular disease? Aging Male 2003;6:217-221.