Relating the disease mutation spectrum to the evolution of the cystic fibrosis transmembrane conductance regulator (CFTR)

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Rishishwar, Lavanya ^a   Varghese, Neha ^a   Tyagi, Eishita ^a   Harvey, Stephen C ^a   Jordan, I King ^a,b   McCarty, Nael A ^c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b PanAmerican Bioinformatics Institute   (Colombia)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYSTIC FIBROSIS; DISEASE SEVERITY; GENE MUTATION; GENETIC CONSERVATION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PREDICTION; REGULATOR GENE; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SITE DIRECTED MUTAGENESIS; TRANSMEMBRANE CONDUCTANCE REGULATOR GENE;

ALGORITHMS; AMINO ACID SEQUENCE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EVOLUTION, MOLECULAR; HUMANS; MUTATION; PROBABILITY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

EID: 84864697205     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042336     Document Type: Article

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