Shilajit attenuates behavioral symptoms of chronic fatigue syndrome by modulating the hypothalamic-pituitary-adrenal axis and mitochondrial bioenergetics in rats

Journal of Ethnopharmacology

Volumn 143, Issue 1, 2012, Pages 91-99

  Surapaneni, Dinesh Kumar ^a   Adapa, Sree Rama Shiva Shanker ^a   Preeti, Kumari ^a   Teja, Gangineni Ravi ^a   Veeraragavan, Muruganandam ^b   Krishnamurthy, Sairam ^a  

^a BANARAS HINDU UNIVERSITY   (India)

^b Natreon Inc   (India)

Author keywords

Animal experiment; Chronic fatigue syndrome; HPA axis; Mitochondrial function; Mitochondrial integrity; Oxidative stress; Prefrontal cortex; Shilajit

Indexed keywords

CATALASE; CORTICOSTERONE; CYTOCHROME C OXIDASE; LACTOPEROXIDASE; NITRIC OXIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SHILAJEET; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE DISMUTASE;

ADRENAL GLAND; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENERGY; CHRONIC FATIGUE SYNDROME; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DRUG EFFECT; ENZYME ACTIVITY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PREFRONTAL CORTEX; RAT;

ADRENAL GLANDS; ANIMALS; ANTIOXIDANTS; ANXIETY; BEHAVIOR, ANIMAL; BEHAVIORAL SYMPTOMS; BENZOPYRANS; BENZOPYRENES; CORTICOSTERONE; FATIGUE SYNDROME, CHRONIC; HUMIC SUBSTANCES; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MAZE LEARNING; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NITRIC OXIDE; ORGAN SIZE; OXIDATIVE STRESS; PHYTOTHERAPY; PITUITARY-ADRENAL SYSTEM; PLANT EXTRACTS; RATS; RATS, INBRED STRAINS; SWIMMING;

ANIMALIA; RATTUS;

EID: 84864684472     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.06.002     Document Type: Article

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