Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 32, 2012, Pages

  Sitia, Giovanni ^a   Aiolfi, Roberto ^a   Di Lucia, Pietro ^a   Mainetti, Marta ^a   Fiocchi, Amleto ^a   Mingozzi, Francesca ^a   Esposito, Antonio ^b   Ruggeri, Zaverio M ^c   Chisari, Francis V ^c   Iannacone, Matteo ^a   Guidotti, Luca G ^a,c  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Antiplatelet drugs; CD8 T cells; Viral hepatitis

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SURVIVAL; CD8+ T LYMPHOCYTE; CELL TRANSFORMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; HEPATITIS B; HEPATITIS B VIRUS; INFLAMMATORY CELL; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER DISEASE; LIVER TOXICITY; LONG TERM CARE; LONG TERM EXPOSURE; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PATHOGENESIS; PRIORITY JOURNAL; THROMBOCYTE; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; ASPIRIN; CARCINOMA, HEPATOCELLULAR; CD8-POSITIVE T-LYMPHOCYTES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; HEPATITIS B, CHRONIC; LIVER; LIVER NEOPLASMS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; PLATELET AGGREGATION INHIBITORS; REAL-TIME POLYMERASE CHAIN REACTION; TICLOPIDINE;

HEPATITIS B VIRUS;

EID: 84864681003     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1209182109     Document Type: Article

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