Fatty acids revert the inhibition of respiration caused by the antidiabetic drug metformin to facilitate their mitochondrial β-oxidation

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1817, Issue 10, 2012, Pages 1768-1775

  González Barroso, M Mar ^a   Anedda, Andrea ^a   Gallardo Vara, Eunate ^a   Redondo Horcajo, Mariano ^a   Rodríguez Sánchez, Leonor ^a   Rial, Eduardo ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Adipocyte; AMPK; Diabetes; Fatty acid oxidation; Metformin; Mitochondria

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; FATTY ACID; GLUCOSE; METFORMIN; PYRUVIC ACID; SUPEROXIDE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; BREATHING RATE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FATTY ACID BLOOD LEVEL; FATTY ACID OXIDATION; GLYCOLYSIS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

3T3-L1 CELLS; ACETYL-COA CARBOXYLASE; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADIPOCYTES; ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; ELECTRON TRANSPORT COMPLEX I; FATTY ACIDS; GLYCOLYSIS; HYPOGLYCEMIC AGENTS; METFORMIN; MICE; MITOCHONDRIA; OXIDATION-REDUCTION; OXYGEN CONSUMPTION;

EID: 84864676553     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2012.02.019     Document Type: Conference Paper

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