Simultaneous quantification of two major active components in radix Angelica sinensis by high-performance liquid chromatography with an internal standard correction method

Instrumentation Science and Technology

Volumn 40, Issue 5, 2012, Pages 416-428

  Fan, Qin ^a   Xia, Peng Fei ^a   Liu, Xiong ^a   Gu, Jia Hui ^a   Wu, Xiao Yu ^b   Zhao, Lei ^a  

^a GANSU UNIVERSITY OF CHINESE MEDICINE   (China)

^b LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Angelica sinensis; high performance liquid chromatography; internal standard correction method; related correction factor

Indexed keywords

ACTIVE COMPONENTS; ANGELICA SINENSIS; CONFIDENCE VALUES; CORRECTION FACTORS; CORRECTION METHOD; FERULIC ACIDS; INTERNAL STANDARDS; PRACTICAL METHOD; REFERENCE STANDARD; REFERENCE SUBSTANCE; RELATIVE RETENTION TIME; STANDARD METHOD;

ELECTROMAGNETIC WAVE ATTENUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY;

EID: 84864665665     PISSN: 10739149     EISSN: 15256030     Source Type: Journal    
DOI: 10.1080/10739149.2012.679718     Document Type: Article

References (55)

1. Zhao, K. J.; Dong, T. T. X.; Tu, P. F.; Song, Z. H.; Lo, C. K.; Tsim, K. W. K. Molecular genetic and chemical assessment of Radix Angelica (Danggui) in China. J. Agric. Food Chem. 2003, 51(9), 2576-2583.
2. Yang, X. B.; Zhao, Y. L. Y. In vivo macrophage activation and physicochemical property of the different polysaccharide fractions purified from Angelica sinensis (Oliv.) Diels. Carbohydr. Polym. 2008, 71(3), 372-379.
3. Deng, S. X.; Chen, S. N.; Yao, P.; De, J. N.; Richard, B. B.; Judy, L. B.; Harry, H. S. F.; Norman, R. F.; Guido, F. P. Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis (Oliv.) Diels. J. Nat. Prod. 2006, 69(4), 536-541. (Pubitemid 43798097)
4. Shao, L. M. Pharmacopoeia of the People's Republic of China (Part I); Chemical Industry Press: Beijing, China, 2010.
5. Yim, T. K.; Wu, W. K. Myocardial protection against ischaemiareperfusior injury by a Polygonum multiflorum extract supplemented ''Dang-Gui decoction for enriching blood'', a compound formulation, ex vivo. Phytother. Res. 2000, 14, 195-199. (Pubitemid 30326014)
6. Wilasrusmee, C.; Kittur, S.; Siddiqui, J.; Bruch, D.; Wilasrusmee, S.; Kittur, D. S. In vitro immunomodulatory effects of ten commonly used herbs on murine lymphocytes. J. Altern. Complement. Med. 2002, 8(4), 467-475. (Pubitemid 34994541)
7. Wang, K. P.; Zeng, F.; Liu, J. Y.; Guo, D.; Zhang, Y. Inhibitory effect of polysaccharides isolated from Angelica sinensis on hepcidin expression. J. Ethnopharmacol. 2011, 134(3), 944-948.
8. Yang, N. Y.; Zhou, G. S.; Tang, Y. P.; Yan, H.; Guo, S.; Liu, P.; Duan, J. A.; Song, B. S.; He, Z. Two new a-pinene derivatives from Angelica sinensis and their anticoagulative activities. Fitoterapia 2011, 82(4), 692-695.
9. Huang, S. J.; Lin, C. M.; Chiang, B H. Protective effects of Angelica sinensis extract on amyloid b-peptide-induced neurotoxicity. Phytomedicine 2008, 15(9), 710-721.
10. Ozaki, Y. Antiinflammatory effect of tetramethylpyrazine and ferulic acid. Biol. Pharm. Bull. 1992, 40(4), 954-956.
11. Yogeeta, S. K.; Gnanapragasam, A.; Kumar, S. S.; Subhashini, R.; Sathivel, A.; Devaki, T. Synergistic interactions of ferulic acid with ascorbic acid: its cardioprotective role during isoproterenol induced mycocardial infraction in rats. Mol. Cell Biochem. 2006, 283(31), 139-146.
12. Ronchetti, D.; Impagnatiello, F.; Guzzetta, M. Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW264.7 macrophages. Eur. J. Pharmacol. 2006, 532(1-2), 162-169.
13. Chan, S. S.; Choi, A. O.; Jones, R. L.; Lin, G. Mechanisms underlying the vasorelaxing effects of butylenephthalide, an active constituent of Ligusticum chuanxiong in rat isolated aorta. Eur. J. Pharmacol. 2006, 537(1-3), 111-117.
14. Lu, Q.; Qiu, T. Q.; Yang, H. Ligustilide inhibits vascular smooth muscle cells proliferation. Eur. J. Pharmacol. 2006, 542(1-3), 136-140. (Pubitemid 44066356)
15. Kuang, X.; Yao, Y.; Du, J. R.; Liu, Y. X.; Wang, C. Y.; Qian, Z. M. Neuroprotective role of Z-ligustilide against forebrain ischemic injury in ICR mice. Brain Res. 2006, 1102(1), 145-153. (Pubitemid 44121580)
16. Yu, Y.; Du, J. R.; Wang, C. Y.; Qian, Z. M. Protection against hydrogen peroxide-induced injury by Z-ligustilide in PC12 cells. Exp. Brain Res. 2008, 184, 307-312. (Pubitemid 350275878)
17. Kan, Q. L. T.; Cho, C. H.; Rudd, J. A.; Lin, G. Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J. Ethnopharmacol. 2008, 120(1), 36-43.
18. Shang, P.; Qian, A. R.; Yang, T. H. Experimental study of anti-tumor effects of polysaccharides from Angelica sinensis. World J. Gastroenterol. 2003, 9(9), 1963-1967. (Pubitemid 37168422)
19. Wang, Y. L.; Liang, Y. Z.; Chen, B. M.; He, Y. K.; Li, B. Y.; Hu, Q. N. LC-DAD-APCI-MS-based screening and analysis of the absorption and metabolite components in plasma from a rabbit administered an oral solution of danggui. Anal. Bioanal. Chem. 2005, 383, 247-254.
20. Wang, H.; Kong, L.; Zou, H. F.; Ni, J. Y.; Zhang, Y. K. Screening and analysis of biologically active compounds in Angelica sinensis by molecular biochromatography. Chromatographia 1999, 50, 439-445. (Pubitemid 30042968)
21. Suzuki, A.; Yamamoto, M.; Jokura, H.; Fujii, A.; Tokimitsu, I.; Hase, T.; Saito, I. Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats. Am. J. Hypertens. 2007, 20(5), 508-513. (Pubitemid 46678706)
22. Cheng, C. Y.; Ho, T. Y.; Lee, E. J.; Su, S. Y.; Tang, N. Y.; Hsieh, C. L. Ferulic acid reduces cerebral infarct through its anti-oxidative and anti-inflammatory effects following transient focal cerebral ischemia in rats. Am. J. Chin. Med. 2008, 36(6), 1105-1119.
23. Cheng, C. Y.; Su, S. Y.; Tang, N. Y.; Ho, T. Y.; Lo, W. Y.; Hsieh, C. L. Ferulic acid inhibits nitric oxide-induced apoptosis by enhancing GABAB1 receptor expression in transient focal cerebral ischemia in rats. Am. J. Chin. Med. 2010, 31(8), 889-899.
24. Chen, D.; Tang, J.; Khatibi, N. H.; Zhu, M.; Li, Y.; Wang, C.; Jiang, R.; Tu, L.; Wang, S. Reducing brain injury after a subarachnoid hemorrhage in rats. J. Pharmacol. Exp. Ther. 2011, 337(3), 663-672.
25. Peng, H. Y.; Du, J. R.; Zhang, G. Y.; Kuang, X.; Liu, Y. X.; Qian, Z. M.; Wang, C. Y. Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats. Biol. Pharm. Bull. 2007, 30(2), 309-312.
26. Wedge, D. E.; Klun, J. A.; Tabanca, N.; Demirci, B.; Ozek, T.; Baser, K. H. C.; Liu, Z.; Zhang, S.; Cantrell, C. L.; Zhang, J. Bioactivity-guided fractionation and GC=MS fingerprinting of Angelica sinensis and Angelica archangelica root components for antifungal and mosquito deterrent activity. J. Agric. Food Chem. 2009, 57(2), 464-470.
27. Wang, Y. L.; Liang, Y. Z.; Chen, B. M. High-performance liquid chromatography with atmospheric pressure chemical ionization and electrospray ionization mass spectrometry for analysis of Angelica sinensis. Phytochem. Anal. 2007, 18(4), 265-274.
28. Lu, G. H.; Chan, K.; Chan, C. L.; Leung, K.; Jiang, Z. H.; Zhao, Z. Z. Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry. J. Chromatogr. A 2004, 1046(1-2), 101-107. (Pubitemid 39044429)
29. Lao, S. C.; Lia, S. P.; Kan, K. W. K.; Lia, P.; Wan, J. B.; Wang, Y. T.; Tina, T. X.; Dong, T. X. T.; Tsimb, K. W. K. Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction. Anal. Chim. Acta 2004, 526(2), 131-137. (Pubitemid 39488093)
30. Zhan, J. Y. X.; Zheng, K. Y. Z.; Zhu, K. Y.; Bi, C. W. C.; Zhang, W. L.; Du, C. Y. Q.; Fu, Q.; Dong, T. T. X.; Choi, R. C. Y.; Tsim, K. W. K.; Lau, D. T. W. Chemical and biological assessment of Angelicae sinensis radix after processing with wine: An orthogonal array design to reveal the optimized conditions. J. Agric. Food Chem. 2011, 59(11), 6091-6098.
31. Lu, G. H.; Chan, K.; Liang, Y. Z.; Leung, K.; Chan, C. L.; Jiang, Z. H.; Zhao, Z. Z. Development of high-performance liquid chromatographic fingerprints for distinguishing Chinese Angelica from related umbelliferae herbs. Talanta 2007, 72(2), 434-436.
32. Lin, L. Z.; He, X. G.; Lian, L. Z.; King, W.; Elliott, J. Liquid chromatographic electrospray mass spectrometric study of Angelica sinensis and chemical changes of Z-ligustilide. J. Chromatogr. A 1998, 810(1-2), 71-79. (Pubitemid 28288229)
33. Zschocke, S.; Liu, J. H.; Stuppner, H.; Bauer, R. Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography and liquid chromatography-mass spectrometry. Phytochem. Anal. 1998, 9(6), 283-290. (Pubitemid 28542569)
34. Lu, G. H.; Chan, K.; Leung, K.; Chan, C. L.; Zhao, Z. Z.; Jiang, Z. H. Assay of free ferulic acid and total ferulic acid for quality assessment of Angelica sinensis. J. Chromatogr. A 2005, 1068(2), 209-219. (Pubitemid 40354183)
35. Zheng, P.; Bi, Z. M.; Li, P.; Qi, L. W.; Yi, L.; Tang, D. LC-DAD-MS determination of the major constituents in radix Angelicae sinensis. Chromatographia 2008, 67(11-12), 973-978.
36. Chen, L. L.; Qi, J.; Chang, Y. X.; Zhu, D. N.; Yu, B. Y. Identification and determination of the major constituents in traditional Chinese medicinal formula Danggui-Shaoyao-San by HPLC-DAD-ESI-MS=MS. J. Pharm. Biomed. Anal. 2009, 50(2), 127-137.
37. Li, P.; Li, S. P.; Lao, S. C.; Fu, C. M.; Kan, K. K. W.; Wang, Y. T. Optimization of pressurized liquid extraction for Z-ligustilide, Z-butylidenephthalide and ferulic acid in Angelica sinensis. J. Pharm. Biomed. Anal. 2006, 40(5), 1073-1079. (Pubitemid 43247443)
38. Wang, H.; Kong, L.; Zou, H. F.; Ni, J. Y.; Zhang, Y. K. Screening and analysis of biologically active compounds in Angelica sinensis by molecular biochromatography. Chromatographia 1999, 50, 439-445. (Pubitemid 30042968)
39. Suzuki, A.; Yamamoto, M.; Jokura, H.; Fujii, A.; Tokimitsu, I.; Hase, T.; Saito, I. Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats. Am. J. Hypertens. 2007, 20(5), 508-513. (Pubitemid 46678706)
40. Cheng, C. Y.; Ho, T. Y.; Lee, E. J.; Su, S. Y.; Tang, N. Y.; Hsieh, C. L. Ferulic acid reduces cerebral infarct through its anti-oxidative and anti-inflammatory effects following transient focal cerebral ischemia in rats. Am. J. Chin. Med. 2008, 36(6), 1105-1119.
41. Cheng, C. Y.; Su, S. Y.; Tang, N. Y.; Ho, T. Y.; Lo, W. Y.; Hsieh, C. L. Ferulic acid inhibits nitric oxide-induced apoptosis by enhancing GABAB1 receptor expression in transient focal cerebral ischemia in rats. Am. J. Chin. Med. 2010, 31(8), 889-899.
42. Chen, D.; Tang, J.; Khatibi, N. H.; Zhu, M.; Li, Y.; Wang, C.; Jiang, R.; Tu, L.; Wang, S. Reducing brain injury after a subarachnoid hemorrhage in rats. J. Pharmacol. Exp. Ther. 2011, 337(3), 663-672.
43. Peng, H. Y.; Du, J. R.; Zhang, G. Y.; Kuang, X.; Liu, Y. X.; Qian, Z. M.; Wang, C. Y. Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats. Biol. Pharm. Bull. 2007, 30(2), 309-312.
44. Wedge, D. E.; Klun, J. A.; Tabanca, N.; Demirci, B.; Ozek, T.; Baser, K. H. C.; Liu, Z.; Zhang, S.; Cantrell, C. L.; Zhang, J. Bioactivity-guided fractionation and GC=MS fingerprinting of Angelica sinensis and Angelica archangelica root components for antifungal and mosquito deterrent activity. J. Agric. Food Chem. 2009, 57(2), 464-470.
45. Wang, Y. L.; Liang, Y. Z.; Chen, B. M. High-performance liquid chromatography with atmospheric pressure chemical ionization and electrospray ionization mass spectrometry for analysis of Angelica sinensis. Phytochem. Anal. 2007, 18(4), 265-274.
46. Lu, G. H.; Chan, K.; Chan, C. L.; Leung, K.; Jiang, Z. H.; Zhao, Z. Z. Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry. J. Chromatogr. A 2004, 1046(1-2), 101-107. (Pubitemid 39044429)
47. Lao, S. C.; Lia, S. P.; Kan, K. W. K.; Lia, P.; Wan, J. B.; Wang, Y. T.; Tina, T. X.; Dong, T. X. T.; Tsimb, K. W. K. Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography-mass spectrometry coupled with pressurized liquid extraction. Anal. Chim. Acta 2004, 526(2), 131-137. (Pubitemid 39488093)
48. Zhan, J. Y. X.; Zheng, K. Y. Z.; Zhu, K. Y.; Bi, C. W. C.; Zhang, W. L.; Du, C. Y. Q.; Fu, Q.; Dong, T. T. X.; Choi, R. C. Y.; Tsim, K. W. K.; Lau, D. T. W. Chemical and biological assessment of Angelicae sinensis radix after processing with wine: An orthogonal array design to reveal the optimized conditions. J. Agric. Food Chem. 2011, 59(11), 6091-6098.
49. Lu, G. H.; Chan, K.; Liang, Y. Z.; Leung, K.; Chan, C. L.; Jiang, Z. H.; Zhao, Z. Z. Development of high-performance liquid chromatographic fingerprints for distinguishing Chinese Angelica from related umbelliferae herbs. Talanta 2007, 72(2), 434-436.
50. Lin, L. Z.; He, X. G.; Lian, L. Z.; King, W.; Elliott, J. Liquid chromatographic electrospray mass spectrometric study of Angelica sinensis and chemical changes of Z-ligustilide. J. Chromatogr. A 1998, 810(1-2), 71-79. (Pubitemid 28288229)
51. Zschocke, S.; Liu, J. H.; Stuppner, H.; Bauer, R. Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography and liquid chromatography-mass spectrometry. Phytochem. Anal. 1998, 9(6), 283-290. (Pubitemid 28542569)
52. Lu, G. H.; Chan, K.; Leung, K.; Chan, C. L.; Zhao, Z. Z.; Jiang, Z. H. Assay of free ferulic acid and total ferulic acid for quality assessment of Angelica sinensis. J. Chromatogr. A 2005, 1068(2), 209-219. (Pubitemid 40354183)
53. Zheng, P.; Bi, Z. M.; Li, P.; Qi, L. W.; Yi, L.; Tang, D. LC-DAD-MS determination of the major constituents in radix Angelicae sinensis. Chromatographia 2008, 67(11-12), 973-978.
54. Chen, L. L.; Qi, J.; Chang, Y. X.; Zhu, D. N.; Yu, B. Y. Identification and determination of the major constituents in traditional Chinese medicinal formula Danggui-Shaoyao-San by HPLC-DAD-ESI-MS=MS. J. Pharm. Biomed. Anal. 2009, 50(2), 127-137.
55. Li, P.; Li, S. P.; Lao, S. C.; Fu, C. M.; Kan, K. K. W.; Wang, Y. T. Optimization of pressurized liquid extraction for Z-ligustilide, Z-butylidenephthalide and ferulic acid in Angelica sinensis. J. Pharm. Biomed. Anal. 2006, 40(5), 1073-1079. (Pubitemid 43247443)