Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages

European Journal of Pharmacology

Volumn 532, Issue 1-2, 2006, Pages 162-169

  Ronchetti, Daniela ^a   Impagnatiello, Francesco ^a   Guzzetta, Massimiliano ^a   Gasparini, Laura ^a,c   Borgatti, Monica ^b   Gambari, Roberto ^b   Ongini, Ennio ^a  

^a Nicox Research Institute   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Ferulic acid; Inflammation; NCX 2057(3 (4 hydroxy 3 methoxyphenyl) 2 propenoic acid 4 (nitrooxy)butyl ester); NF B (nuclear factor kappa B); Nitric oxide; RAW 264.7 macrophages

Indexed keywords

3 (4 HYDROXY 3 METHOXYPHENYL) 2 PROPENOIC ACID 4 (HYDROXYL)BUTYL ESTER; 3 (4 HYDROXY 3 METHOXYPHENYL) 2 PROPENOIC ACID 4 (NITROOXY)BUTYL ESTER; ANTIINFLAMMATORY AGENT; FERULIC ACID; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NCX 2057; NCX 2059; STAT1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NF IL2A; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CELL LINE; CHRONIC INFLAMMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ENZYME REGULATION; IC 50; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; BUTANES; CELL LINE; COUMARIC ACIDS; ESTERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; NITRO COMPOUNDS; RNA, MESSENGER;

EID: 33644531884     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.12.034     Document Type: Article

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