Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins

Brain Research

Volumn 1470, Issue , 2012, Pages 59-68

  Han, Ren Wen ^a,e,f   Zhang, Rui San ^c,d   Chang, Min ^c,d   Peng, Ya Li ^c,d   Wang, Pei ^c,d   Hu, Sheng Quan ^b   Choi, Chung Lit ^b   Yin, Ming ^a   Wang, Rui ^b,c,d   Han, Yi Fan ^b,f  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^c LANZHOU UNIVERSITY   (China)

^d LANZHOU UNIVERSITY   (China)

^e State Key Laboratory of Chinese Medicine and Molecular Pharmacology ^*  (China)

^f State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

Author keywords

Bis(heptyl) cognitin; Bis(propyl) cognitin; Learning and memory; Morris water maze; Novel object recognition; Scopolamine

Indexed keywords

(HEPTYL) COGNITIN; (PROPYL) COGNITIN; NOOTROPIC AGENT; SCOPOLAMINE; TACRINE; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL EXPERIMENT; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECOGNITION; SPATIAL MEMORY;

ANALYSIS OF VARIANCE; ANIMALS; CHOLINERGIC ANTAGONISTS; CHOLINESTERASE INHIBITORS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED STRAINS; REACTION TIME; RECOGNITION (PSYCHOLOGY); RETENTION (PSYCHOLOGY); SCOPOLAMINE HYDROBROMIDE; TACRINE;

MUS;

EID: 84864594019     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.06.015     Document Type: Article

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