Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells

European Cells and Materials

Volumn 23, Issue , 2012, Pages 320-332

  Boeuf, S ^a   Graf, F ^a   Fischer, J ^a   Moradi, B ^a   Little, C B ^b   Richter, W ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Aggrecan neoepitopes; Aggrecanase; Cartilage development; Inflammation; Interleukin 1 ; Mesenchymal stem cells; Proteoglycan depletion; Regenerative medicine

Indexed keywords

A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIF 16; A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIF 9; ADAMTS1 PROTEIN; AGGRECAN; AGGRECANASE 1; AGGRECANASE 2; COLLAGEN; FURIN; INTERLEUKIN 1BETA; MESSENGER RNA; METALLOPROTEINASE; PROTEIN COL2A1; UNCLASSIFIED DRUG; ADAM PROTEIN; ADAMTS1 PROTEIN, HUMAN; ADAMTS16 PROTEIN, HUMAN; ADAMTS5 PROTEIN, HUMAN; ADAMTS9 PROTEIN, HUMAN; AGGRECANASE; AGGRECANASE-1; EPITOPE; PROCOLLAGEN N PROTEINASE; PROTEINASE;

ADULT; AGED; ARTHRITIS; ARTICLE; CELL DIFFERENTIATION; CHONDROGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITOPE MAPPING; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE REGENERATION; UPREGULATION; ADOLESCENT; AMINO ACID SEQUENCE; CELL CULTURE; CHILD; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED;

ADAM PROTEINS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGGRECANS; AMINO ACID SEQUENCE; CELLS, CULTURED; CHILD; CHONDROGENESIS; ENDOPEPTIDASES; EPITOPES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; MESENCHYMAL STEM CELLS; MIDDLE AGED; PROCOLLAGEN N-ENDOPEPTIDASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84864592097     PISSN: 14732262     EISSN: None     Source Type: Journal    
DOI: 10.22203/eCM.v023a25     Document Type: Article

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