1H NMR spectroscopy of serum reveals unique metabolic fingerprints associated with subtypes of surgically induced osteoarthritis in sheep

Journal of Proteome Research

Volumn 11, Issue 8, 2012, Pages 4261-4268

  Maher, Anthony D ^a   Coles, Chantal ^a,b   White, Jason ^b,e   Bateman, John F ^b   Fuller, Emily S ^c   Burkhardt, Dan ^c   Little, Christopher B ^c   Cake, Martin ^d   Read, Richard ^d   McDonagh, Matthew B ^a   Rochfort, Simone Jane ^a  

^a Discovery Technology   (Finland)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d MURDOCH UNIVERSITY   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

metabolomics; metabonomics; nuclear magnetic resonance (NMR); osteoarthritis; principal components analysis; sheep

Indexed keywords

3 METHYLHISTIDINE; AMINO ACID; DIMETHYL SULFONE; BIOLOGICAL MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; MENISCAL DESTABILIZATION; METABOLOMICS; NONHUMAN; OSTEOARTHRITIS; PARTIAL LEAST SQUARES REGRESSION; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SHAM PROCEDURE; SHEEP; SURGICAL TECHNIQUE; ANIMAL; BLOOD; KNEE OSTEOARTHRITIS; METABOLOME; NONPARAMETRIC TEST; PATHOLOGY;

ANIMALIA; OVIS ARIES;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; BIOLOGICAL MARKERS; FEMALE; METABOLOME; OSTEOARTHRITIS, KNEE; PRINCIPAL COMPONENT ANALYSIS; SHEEP; STATISTICS, NONPARAMETRIC;

EID: 84864580172     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300368h     Document Type: Article

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