KIR/HLA interactions and pathogen immunity

Journal of Biomedicine and Biotechnology

Volumn 2011, Issue , 2011, Pages

  Khakoo, Salim I ^a   Jamil, Khaleel M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A11 ANTIGEN; HLA A3 ANTIGEN; HLA ANTIGEN; HLA B ANTIGEN; HLA C1 ANTIGEN; HLA C2 ANTIGEN; HLA G ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL4; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL5; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS5; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS1; UNCLASSIFIED DRUG;

HEPATITIS C; HERPES SIMPLEX; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNITY; LYMPHOCYTE ACTIVATION; NATURAL KILLER CELL; NONHUMAN; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; WART VIRUS; ANIMAL; BIOLOGICAL MODEL; IMMUNOLOGY; INNATE IMMUNITY;

HEPATITIS C VIRUS;

ANIMALS; HLA ANTIGENS; HUMANS; IMMUNITY, INNATE; KILLER CELLS, NATURAL; MODELS, IMMUNOLOGICAL; RECEPTORS, KIR;

EID: 79959348673     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/298348     Document Type: Review

References (86)

1. Horowitz A., Behrens R. H., Okell L., Fooks A. R., Riley E. M., NK cells as effectors of acquired immune responses: effector CD4 + T cell-dependent activation of NK cells following vaccination Journal of Immunology 2010 185 5 2808 2818
2. De Maria A., Fogli M., Mazza S., Basso M., Picciotto A., Costa P., Congia S., Mingari M. C., Moretta L., Increased natural cytotoxicity receptor expression and relevant IL-10 production in NK cells from chronically infected viremic HCV patients European Journal of Immunology 2007 37 2 445 455 (Pubitemid 46915584)
3. Moretta A., Tambussi G., Bottino C., Tripodi G., Merli A., Ciccone E., Pantaleo G., Moretta L., A novel surface antigen expressed by a subset of human CD3 - CD16 + natural killer cells. Role in cell activation and regulation of cytolytic function Journal of Experimental Medicine 1990 171 3 695 714 (Pubitemid 20088976)
4. Ljunggren H. G., Karre K., In search of the 'missing self': MHC molecules and NK cell recognition Immunology Today 1990 11 7 237 244 (Pubitemid 20198988)
5. Parham P., MHC class I molecules and KIRS in human history, health and survival Nature Reviews Immunology 2005 5 3 201 214 (Pubitemid 40364822)
6. Braud V. M., Allan D. S. J., O'Callaghan C. A., Soderstrom K., D'Andrea A., Ogg G. S., Lazetic S., Young N. T., Bell J. I., Phillips J. H., Lanler L. L., McMichael A. J., HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C Nature 1998 391 6669 795 799 (Pubitemid 28099678)
7. Shilling H. G., Guethlein L. A., Cheng N. W., Gardiner C. M., Rodriguez R., Tyan D., Parham P., Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype Journal of Immunology 2002 168 5 2307 2315 (Pubitemid 34171832)
8. Yawata M., Yawata N., Draghi M., Partheniou F., Little A. M., Parham P., MHC class I specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response Blood 2008 112 6 2369 2380
9. Wende H., Colonna M., Ziegler A., Volz A., Organization of the leukocyte receptor cluster (LRC) on human Chromosome 19q13.4 Mammalian Genome 1999 10 2 154 160 (Pubitemid 29390539)
10. Boyton R. J., Altmann D. M., Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease Clinical and Experimental Immunology 2007 149 1 1 8 (Pubitemid 46897116)
11. Khakoo S. I., Carrington M., KIR and disease: a model system or system of models? Immunological Reviews 2006 214 1 186 201 (Pubitemid 44707911)
12. Canavez F., Young N. T., Guethlein L. A., Rajalingam R., Khakoo S. I., Shum B. P., Parham P., Comparison of chimpanzee and human leukocyte Ig-like receptor genes reveals framework and rapidly evolving genes Journal of Immunology 2001 167 10 5786 5794 (Pubitemid 33062770)
13. Parham P., Abi-Rached L., Matevosyan L., Moesta A. K., Norman P. J., Older Aguilar A. M., Guethlein L. A., Primate-specific regulation of natural killer cells Journal of Medical Primatology 2010 39 4 194 212
14. Marsh S. G. E., Parham P., Dupont B., Geraghty D. E., Trowsdale J., Middleton D., Vilches C., Carrington M., Witt C., Guethlein L. A., Shilling H., Garcia C. A., Hsu K. C., Wain H., Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002 Human Immunology 2003 64 6 648 654 (Pubitemid 36706060)
15. Hiby S. E., Walker J. J., O'Shaughnessy K. M., Redman C. W. G., Carrington M., Trowsdale J., Moffett A., Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success Journal of Experimental Medicine 2004 200 8 957 965 (Pubitemid 39431121)
16. Hiby S. E., Ashrafian-Bonab M., Farrell L., Single R. M., Balloux F., Carrington M., Moffett A., Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations Immunogenetics 2010 62 2 65 73
17. Hiby S. E., Apps R., Sharkey A. M., Farrell L. E., Gardner L., Mulder A., Claas F. H., Walker J. J., Redman C. C., Morgan L., Tower C., Regan L., Moore G. E., Carrington M., Moffett A., Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2 Journal of Clinical Investigation 2010 120 11 4102 4110
18. Lu Z., Zhang B., Chen S., Gai Z., Feng Z., Liu X., Liu Y., Wen X., Li L., Jiao Y., Ma C., Shao S., Cui X., Chen G., Li J., Zhao Y., Association of KIR genotypes and haplotypes with susceptibility to chronic hepatitis B virus infection in Chinese Han population Cellular Molecular Immunology 2008 5 6 457 463
19. Cheent K., Khakoo S. I., Natural killer cells: integrating diversity with function Immunology 2009 126 4 449 457
20. Kikuchi-Maki A., Catina T. L., Campbell K. S., Cutting edge: KIR2DL4 transduces signals into human NK cells through association with the Fc receptor protein Journal of Immunology 2005 174 7 3859 3863 (Pubitemid 40395957)
21. Khakoo S. I., Rajalingam R., Shum B. P., Weidenbach K., Flodin L., Muir D. G., Canavez F., Cooper S. L., Valiante N. M., Lanier L. L., Parham P., Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans Immunity 2000 12 6 687 698
22. Colonna M., Borsellino G., Falco M., Ferrara G. B., Strominger J. L., HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells Proceedings of the National Academy of Sciences of the United States of America 1993 90 24 12000 12004 (Pubitemid 24008768)
23. Wagtmann N., Rajagopalan S., Winter C. C., Peruzzi M., Long E. O., Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer Immunity 1995 3 6 801 809 (Pubitemid 26092193)
24. Moesta A. K., Norman P. J., Yawata M., Yawata N., Gleimer M., Parham P., Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C Than KIR2DL3 Journal of Immunology 2008 180 6 3969 3979
25. Winter C. C., Gumperz J. E., Parham P., Long E. O., Wagtmann N., Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition Journal of Immunology 1998 161 2 571 577 (Pubitemid 28323516)
26. Gumperz J. E., Litwin V., Phillips J. H., Lanier L. L., Parham P., The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor Journal of Experimental Medicine 1995 181 3 1133 1144
27. Pende D., Biassoni R., Cantoni C., Verdiani S., Falco M., Di Donato C., Accame L., Bottino C., Moretta A., Moretta L., The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide- linked dimer Journal of Experimental Medicine 1996 184 2 505 518 (Pubitemid 26324104)
28. Stewart C. A., Laugier-Anfossi F., Vly F., Saulquin X., Riedmuller J., Tisserant A., Gauthiers L., Romagn F., Ferracci G., Arosa F. A., Moretta A., Sun P. D., Ugolini S., Vivier E., Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors Proceedings of the National Academy of Sciences of the United States of America 2005 102 37 13224 13229 (Pubitemid 41325005)
29. Moesta A. K., Graef T., Abi-Rached L., Aguilar A. M. O., Guethlein L. A., Parham P., Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I Journal of Immunology 2010 185 7 4233 4237
30. Raulet D. H., Vance R. E., Self-tolerance of natural killer cells Nature Reviews Immunology 2006 6 7 520 531 (Pubitemid 43980524)
31. Kim S., Poursine-Laurent J., Truscott S. M., Lybarger L., Song Y. J., Yang L., French A. R., Sunwoo J. B., Lemieux S., Hansen T. H., Yokoyama W. M., Licensing of natural killer cells by host major histocompatibility complex class I molecules Nature 2005 436 7051 709 713 (Pubitemid 41117274)
32. MacDonald H. R., NK cell tolerance: revisiting the central dogma Nature Immunology 2005 6 9 868 869 (Pubitemid 43090440)
33. Alter G., Reduced frequencies of NKp30+NKp46+, CD161+ and NKG2D+ NK cells in acute HCV infection may predict viral clearance. Journal of Hepatology, 2010. In press
34. Amadei B., Urbani S., Cazaly A., Fisicaro P., Zerbini A., Ahmed P., Missale G., Ferrari C., Khakoo S. I., Activation of natural killer cells during acute infection with hepatitis C virus Gastroenterology 2010 138 4 1536 1545
35. Pelletier S., Drouin C., Bdard N., Khakoo S. I., Bruneau J., Shoukry N. H., Increased degranulation of natural killer cells during acute HCV correlates with the magnitude of virus-specific T cell responses Journal of Hepatology 2010 53 5 805 816
36. Morishima C., Paschal D. M., Wang C. C., Yoshihara C. S., Wood B. L., Yeo A. E. T., Emerson S. S., Shuhart M. C., Gretch D. R., Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing Hepatology 2006 43 3 573 580
37. Corado J., Toro F., Rivera H., Bianco N. E., Deibis L., De Sanctis J. B., Impairment of natural killer (NK) cytotoxic activity in hepatitis C virus (HCV) infection Clinical and Experimental Immunology 1997 109 3 451 457 (Pubitemid 27402312)
38. Pr G., Rukavina D., Podack E. R., Hornyi M., Szekeres-Barth J., Hegeds G., Pal M., Szereday L., Mzsik G., Pr A., Decrease in CD3-negative-CD8dim + and V 2/V 9 TcR + peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity is associated with chronic hepatitis C virus infection Journal of Hepatology 2002 37 4 514 522
39. Bonavita M. S., Franco A., Paroli M., Santilio I., Benvenuto R., De Petrillo G., Levrero M., Perrone A., Balsano C., Barnaba V., Normalization of depressed natural killer activity after interferon- therapy is associated with a low frequency of relapse in patients with chronic hepatitis C International Journal of Tissue Reactions 1993 15 1 11 16 (Pubitemid 23308561)
40. Khakoo S. I., Thio C. L., Martin M. P., Brooks C. R., Gao X., Astemborski J., Cheng J., Goedert J. J., Vlahov D., Hilgartner M., Cox S., Little A. M., Alexander G. J., Cramp M. E., O'Brien S. J., Rosenberg W. M. C., Thomas D. L., Carrington M., HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection Science 2004 305 5685 872 874 (Pubitemid 39038423)
41. Romero V., Azocar J., Ziga J., Clavijo O. P., Terreros D., Gu X., Husain Z., Chung R. T., Amos C., Yunis E. J., Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome Molecular Immunology 2008 45 9 2429 2436
42. Fadda L., Borhis G., Ahmed P., Cheent K., Pageon S. V., Cazaly A., Stathopoulos S., Middleton D., Mulder A., Claas F. H. J., Elliott T., Davis D. M., Purbhoo M. A., Khakoo S. I., Peptide antagonism as a mechanism for NK cell activation Proceedings of the National Academy of Sciences of the United States of America 2010 107 22 10160 10165
43. Ahlenstiel G., Martin M. P., Gao X., Carrington M., Rehermann B., Distinct KIR/HLA compound genotypes affect the kinetics of human antiviral natural killer cell responses Journal of Clinical Investigation 2008 118 3 1017 1026 (Pubitemid 351364609)
44. Knapp S., Warshow U., Hegazy D., Brackenbury L., Guha I. N., Fowell A., Little A. M., Alexander G. J., Rosenberg W. M. C., Cramp M. E., Khakoo S. I., Consistent beneficial effects of killer cell immunoglobulin-like receptor 2dl3 and group 1 human leukocyte antigen-c following exposure to hepatitis c virus Hepatology 2010 51 4 1168 1175
45. Vidal-Castieira J. R., Lpez-Vzquez A., Daz-Pea R., Alonso-Arias R., Martnez-Borra J., Prez R., Fernndez-Surez J., Meln S., Prieto J., Rodrigo L., Lpez-Larrea C., Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection Journal of Virology 2010 84 1 475 481
46. Lpez-Vzquez A., Rodrigo L., Martnez-Borra J., Prez R., Rodrguez M., Fdez-Morera J. L., Fuentes D., Rodrguez-Rodero S., Gonzlez S., Lpez-Larrea C., Protective effect of the HLA-Bw4I80 epitope and the killer cell immunoglobulin-like receptor 3DS1 gene against the development of hepatocellular carcinoma in patients with hepatitis C virus infection Journal of Infectious Diseases 2005 192 1 162 165 (Pubitemid 40863869)
47. Ziga J., Romero V., Azocar J., Terreros D., Vargas-Rojas M. I., Torres-Garca D., Jimnez-Alvarez L., Vargas-Alarcn G., Granados-Montiel J., Husain Z., Chung R. T., Alper C. A., Yunis E. J., Protective KIR-HLA interactions for HCV infection in intravenous drug users Molecular Immunology 2009 46 13 2723 2727
48. Carneiro V. L., Lemaire D. C., Bendicho M. T., Souza S. L., Cavalcante L. N., Angelo A. L., Freire S. M., Mendes C. M. C., Santana N., Lyra L. G. C., Lyra A. C., Natural killer cell receptor and HLA-C gene polymorphisms among patients with hepatitis C: a comparison between sustained virological responders and non-responders Liver International 2010 30 4 567 573
49. Rauch A., Laird R., McKinnon E., Telenti A., Furrer H., Weber R., Smillie D., Gaudieri S., Influence of inhibitory killer immunoglobulin-like receptors and their HLA-C ligands on resolving hepatitis C virus infection Tissue Antigens 2007 69 1 237 240 (Pubitemid 46625892)
50. Oliviero B., Varchetta S., Paudice E., Michelone G., Zaramella M., Mavilio D., De Filippi F., Bruno S., Mondelli M. U., Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections Gastroenterology 2009 137 3 1151 1160.e7
51. Harrison R. J., Ettorre A., Little A.-M., Khakoo S. I., Association of NKG2A with treatment for chronic hepatitis C virus infection Clinical and Experimental Immunology 2010 161 2 306 314
52. Ahlenstiel G., Titerence R. H., Koh C., Edlich B., Feld J. J., Rotman Y., Ghany M. G., Hoofnagle J. H., Liang T. J., Heller T., Rehermann B., Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa-dependent manner Gastroenterology 2010 138 1 325 335.e2
53. World Health Organization, Fact Sheet 204. 2008, http://www.who.int/ mediacentre/factsheets/fs204/en/
54. Custer B., Sullivan S. D., Hazlet T. K., Iloeje U., Veenstra D. L., Kowdley K. V., Global epidemiology of hepatitis B virus Journal of clinical gastroenterology 2004 38 10 S158 S168
55. Gao X., Jiao Y., Wang L., Liu X., Sun W., Cui B., Chen Z., Zhao Y., Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B Clinical Immunology 2010 137 1 139 146
56. Martin M. P., Gao X., Lee J. H., Nelson G. W., Detels R., Goedert J. J., Buchbinder S., Hoots K., Vlahov D., Trowsdale J., Wilson M., O'Brien S. J., Carrington M., Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS Nature Genetics 2002 31 4 429 434 (Pubitemid 35154456)
57. Qi Y., Martin M. P., Gao X., Jacobson L., Goedert J. J., Buchbinder S., Kirk G. D., O'Brien S. J., Trowsdale J., Carrington M., KIR/HLA pleiotropism: protection against both HIV and opportunistic infections. PLoS Pathogens 2006 2 8, article e79
58. Barbour J. D., Sriram U., Caillier S. J., Levy J. A., Hecht F. M., Oksenberg J. R., Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression. PLoS pathogens 2007 3 4, article e43
59. Cohen G. B., Gandhi R. T., Davis D. M., Mandelboim O., Chen B. K., Strominger J. L., Baltimore D., The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells Immunity 1999 10 6 661 671 (Pubitemid 29302919)
60. Biassoni R., Pessino A., Malaspina A., Cantoni C., Bottino C., Sivori S., Moretta L., Moretta A., Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules European Journal of Immunology 1997 27 12 3095 3099 (Pubitemid 28018001)
61. Katz G., Markel G., Mizrahi S., Arnon T. I., Mandelboim O., Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4 Journal of Immunology 2001 166 12 7260 7267 (Pubitemid 32525600)
62. Malnati M. S., Peruzzi M., Parker K. C., Biddison W. E., Ciccone E., Moretta A., Long E. O., Peptide specificity in the recognition of MHC class I by natural killer cell clones Science 1995 267 5200 1016 1018
63. Gaudieri S., DeSantis D., McKinnon E., Moore C., Nolan D., Witt C. S., Mallal S. A., Christiansen F. T., Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression Genes and Immunity 2005 6 8 683 690 (Pubitemid 41741713)
64. Boulet S., Sharafi S., Simic N., Bruneau J., Routy J. P., Tsoukas C. M., Bernard N. F., Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals AIDS 2008 22 5 595 599 (Pubitemid 351640592)
65. Alter G., Martin M. P., Teigen N., Carr W. H., Suscovich T. J., Schneidewind A., Streeck H., Waring M., Meier A., Brander C., Lifson J. D., Allen T. M., Carrington M., Altfeld M., Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes Journal of Experimental Medicine 2007 204 12 3027 3036 (Pubitemid 350179568)
66. Long B. R., Ndhlovu L. C., Oksenberg J. R., Lanier L. L., Hecht F. M., Nixon D. F., Barbour J. D., Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection Journal of Virology 2008 82 10 4785 4792 (Pubitemid 351657040)
67. Thomas R., Yamada E., Alter G., Martin M. P., Bashirova A. A., Norman P. J., Altfeld M., Parham P., Anderson S. K., McVicar D. W., Carrington M., Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation? Journal of Immunology 2008 180 10 6743 6750
68. Martin M. P., Qi Y., Gao X., Yamada E., Martin J. N., Pereyra F., Colombo S., Brown E. E., Shupert W. L., Phair J., Goedert J. J., Buchbinder S., Kirk G. D., Telenti A., Connors M., O'Brien S. J., Walker B. D., Parham P., Deeks S. G., McVicar D. W., Carrington M., Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1 Nature Genetics 2007 39 6 733 740 (Pubitemid 46848586)
69. O'Connor G. M., Guinan K. J., Cunningham R. T., Middleton D., Parham P., Gardiner C. M., Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells Journal of Immunology 2007 178 1 235 241 (Pubitemid 46033606)
70. Rajagopalan S., Bryceson Y. T., Kuppusamy S. P., Geraghty D. E., Van Der Meer A., Joosten I., Long E. O., Activation of NK cells by an endocytosed receptor for soluble HLA-G PLoS Biology 2006 4 1, article no. e9
71. Boulet S., Song R., Kamya P., Bruneau J., Shoukry N. H., Tsoukas C. M., Bernard N. F., HIV protective KIR3DL1 and HLA-B genotypes influence NK cell function following stimulation with HLA-devoid cells Journal of Immunology 2010 184 4 2057 2064
72. Fellay J., Shianna K. V., Ge D., Colombo S., Ledergerber B., Weale M., Zhang K., Gumbs C., Castagna A., Cossarizza A., Cozzi-Lepri A., De Luca A., Easterbrook P., Francioli P., Mallal S., Martinez-Picado J., Miro J. M., Obel N., Smith J. P., Wyniger J., Descombes P., Antonarakis S. E., Letvin N. L., McMichael A. J., Haynes B. F., Telenti A., Goldstein D. B., A whole-genome association study of major determinants for host control of HIV-1 Science 2007 317 5840 944 947 (Pubitemid 47301321)
73. Pereyra F., Jia X., McLaren P. J., Telenti A., De Bakker P. I. W., Walker B. D., The major genetic determinants of HIV-1 control affect HLA class I peptide presentation Science 2010 330 6010 1551 1557
74. Makadzange A. T., Gillespie G., Dong T., Kiama P., Bwayo J., Kimani J., Plummer F., Easterbrook P., Rowland-Jones S. L., Characterization of an HLA-C-restricted CTL response in chronic HIV infection European Journal of Immunology 2010 40 4 1036 1041
75. Jennes W., Verheyden S., Demanet C., Adj-Tour C. A., Vuylsteke B., Nkengasong J. N., Kestens L., Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands Journal of Immunology 2006 177 10 6588 6592 (Pubitemid 44715020)
76. Thomas R., Apps R., Qi Y., Gao X., Male V., O'Huigin C., O'Connor G., Ge D., Fellay J., Martin J. N., Margolick J., Goedert J. J., Buchbinder S., Kirk G. D., Martin M. P., Telenti A., Deeks S. G., Walker B. D., Goldstein D., McVicar D. W., Moffett A., Carrington M., HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C Nature Genetics 2009 41 12 1290 1294
77. Biron C. A., Byron K. S., Sullivan J. L., Severe herpesvirus infections in an adolescent without natural killer cells New England Journal of Medicine 1989 320 26 1731 1735 (Pubitemid 19163129)
78. Cook M., Briggs D., Craddock C., Mahendra P., Milligan D., Fegan C., Darbyshire P., Lawson S., Boxall E., Moss P., Donor KIR genotype has a major influence on the rate of cytomegalovirus reactivation following T-cell replete stem cell transplantation Blood 2006 107 3 1230 1232 (Pubitemid 43156330)
79. Chen C., Busson M., Rocha V., Appert M. L., Lepage V., Dulphy N., Haas P., Soci G., Toubert A., Charron D., Loiseau P., Activating KIR genes are associated with CMV reactivation and survival after non-T-cell depleted HLA-identical sibling bone marrow transplantation for malignant disorders Bone Marrow Transplantation 2006 38 6 437 444 (Pubitemid 44340375)
80. Zaia J. A., Sun J. Y., Gallez-Hawkins G. M., Thao L., Oki A., Lacey S. F., Dagis A., Palmer J., Diamond D. J., Forman S. J., Senitzer D., The effect of single and combined activating killer immunoglobulin-like receptor genotypes on cytomegalovirus infection and immunity after hematopoietic cell transplantation Biology of Blood and Marrow Transplantation 2009 15 3 315 325
81. Bonagura V. R., Du Z., Ashouri E., Luo L., Hatam L. J., DeVoti J. A., Rosenthal D. W., Steinberg B. M., Abramson A. L., Gjertson D. W., Reed E. F., Rajalingam R., Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis Human Immunology 2010 71 2 212 219
82. Carrington M., Wang S., Martin M. P., Gao X., Schiffman M., Cheng J., Herrero R., Rodriguez A. C., Kurman R., Mortel R., Schwartz P., Glass A., Hildesheim A., Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci Journal of Experimental Medicine 2005 201 7 1069 1075 (Pubitemid 40524675)
83. Estefana E., Gmez-Lozano N., Portero F., De Pablo R., Sols R., Seplveda S., Vaquero M., Gonzlez M. A., Surez E., Roustn G., Vilches C., Influence of KIR gene diversity on the course of HSV-1 infection: resistance to the disease is associated with the absence of KIR2DL2 and KIR2DS2 Tissue Antigens 2007 70 1 34 41 (Pubitemid 46890276)
84. Korbel D. S., Finney O. C., Riley E. M., Natural killer cells and innate immunity to protozoan pathogens International Journal for Parasitology 2004 34 13-14 1517 1528
85. Artavanis-Tsakonas K., Eleme K., McQueen K. L., Cheng N. W., Parham P., Davis D. M., Riley E. M., Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes Journal of Immunology 2003 171 10 5396 5405 (Pubitemid 37432826)
86. Baratin M., Roetynck S., Pouvelle B., Lemmers C., Viebig N. K., Johansson S., Bierling P., Scherf A., Gysin J., Vivier E., Ugolini S., Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium falciparum-infected erythrocytes by natural killer cells PLoS One 2007 2 2, article no. e228