Low-dose fluvastatin reverses the hypoxic pulmonary adventitial fibroblast phenotype in experimental pulmonary hypertension

American Journal of Respiratory Cell and Molecular Biology

Volumn 47, Issue 2, 2012, Pages 140-148

  Carlin, Christopher M ^a   Celnik, Daniel F ^a   Pak, Oleg ^a   Wadsworth, Roger ^b   Peacock, Andrew J ^a   Welsh, David J ^a  

^a WESTERN INFIRMARY   (United Kingdom)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Hypoxia; Pulmonary hypertension; Statins

Indexed keywords

BOSENTAN; CHOLESTEROL; FLUINDOSTATIN; MITOGEN ACTIVATED PROTEIN KINASE P38; RAC1 PROTEIN; SILDENAFIL; UNIPROST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; COW; HYPOXIA; INTRACELLULAR SIGNALING; LOW DRUG DOSE; LUNG FIBROBLAST; MALE; NONHUMAN; PHENOTYPE; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER;

ANIMALS; ANOXIA; CATTLE; CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; CHOLESTEROL; FATTY ACIDS, MONOUNSATURATED; FIBROBLASTS; HYPERTENSION, PULMONARY; INDOLES; LUNG; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PHOSPHORYLATION; PULMONARY ARTERY; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

ANIMALIA; BOVINAE; RATTUS;

EID: 84864541728     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0411OC     Document Type: Article

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