메뉴 건너뛰기




Volumn 20, Issue 6, 2007, Pages 718-725

p38 MAP kinase: Essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation

Author keywords

Hypoxia; Molecular biology; Pulmonary hypertension; Remodelling

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; HYPOXIA INDUCIBLE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE P38; THYMIDINE;

EID: 34548820973     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2006.08.007     Document Type: Article
Times cited : (40)

References (27)
  • 1
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo G.E., Barst R.J., Ayres S.M., Bergofsky E.H., Brundage B.H., Detre K.M., et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 115 5 (1991) 343-349
    • (1991) Ann Intern Med , vol.115 , Issue.5 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3    Bergofsky, E.H.4    Brundage, B.H.5    Detre, K.M.6
  • 2
  • 3
    • 0037111313 scopus 로고    scopus 로고
    • Characterization of high-altitude pulmonary hypertension in the Kyrgyz: association with angiotensin-converting enzyme genotype
    • Aldashev A.A., Sarybaev A.S., Sydykov A.S., Kalmyrzaev B.B., Kim E.V., Mamanova L.B., et al. Characterization of high-altitude pulmonary hypertension in the Kyrgyz: association with angiotensin-converting enzyme genotype. Am J Respir Crit Care Med 166 10 (2002) 1396-1402
    • (2002) Am J Respir Crit Care Med , vol.166 , Issue.10 , pp. 1396-1402
    • Aldashev, A.A.1    Sarybaev, A.S.2    Sydykov, A.S.3    Kalmyrzaev, B.B.4    Kim, E.V.5    Mamanova, L.B.6
  • 4
    • 0018333675 scopus 로고
    • Hypoxia and the incorporation of 3H-thymidine by cells of the rat pulmonary arteries and alveolar wall
    • Meyrick B., and Reid L. Hypoxia and the incorporation of 3H-thymidine by cells of the rat pulmonary arteries and alveolar wall. Am J Pathol 96 1 (1979) 51-69
    • (1979) Am J Pathol , vol.96 , Issue.1 , pp. 51-69
    • Meyrick, B.1    Reid, L.2
  • 5
    • 0018824798 scopus 로고
    • Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression
    • Meyrick B., and Reid L. Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression. Am J Pathol 100 1 (1980) 151-169
    • (1980) Am J Pathol , vol.100 , Issue.1 , pp. 151-169
    • Meyrick, B.1    Reid, L.2
  • 6
    • 0036900716 scopus 로고    scopus 로고
    • Ambulatory pulmonary artery pressure monitoring during sleep and exercise in normal individulas and pateints with COPD
    • Raeside D.A., Brown A., Patel K.R., Welsh D., and Peacock A.J. Ambulatory pulmonary artery pressure monitoring during sleep and exercise in normal individulas and pateints with COPD. Thorax 57 12 (2002) 1050-1053
    • (2002) Thorax , vol.57 , Issue.12 , pp. 1050-1053
    • Raeside, D.A.1    Brown, A.2    Patel, K.R.3    Welsh, D.4    Peacock, A.J.5
  • 7
    • 84980110245 scopus 로고
    • Observations on the pulmonary arterial blood pressure in the cat
    • Euler U.S.V., and Liljestrand G. Observations on the pulmonary arterial blood pressure in the cat. Acta Phys Scandinavica 12 (1946) 301-320
    • (1946) Acta Phys Scandinavica , vol.12 , pp. 301-320
    • Euler, U.S.V.1    Liljestrand, G.2
  • 8
    • 0023755683 scopus 로고
    • Effect of hypoxia on bronchial circulation
    • Wagner E.M., and Mitzner W.A. Effect of hypoxia on bronchial circulation. Am J Physiol 65 4 (1988) 1627-1633
    • (1988) Am J Physiol , vol.65 , Issue.4 , pp. 1627-1633
    • Wagner, E.M.1    Mitzner, W.A.2
  • 9
    • 0032429520 scopus 로고    scopus 로고
    • Hypoxia enhances cellular proliferation and inositol 1,4,5-triphosphate generation in fibroblasts from bovine pulmonary artery but not from mesenteric artery
    • Welsh D.J., Scott P., Plevin R., Wadsworth R., and Peacock A.J. Hypoxia enhances cellular proliferation and inositol 1,4,5-triphosphate generation in fibroblasts from bovine pulmonary artery but not from mesenteric artery. Am J Respir Crit Care Med 158 (1998) 1757-1762
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1757-1762
    • Welsh, D.J.1    Scott, P.2    Plevin, R.3    Wadsworth, R.4    Peacock, A.J.5
  • 10
    • 0035880173 scopus 로고    scopus 로고
    • Chronic hypoxia induces constitutive p38 mitogen-activated protein kinase activity that correlated with enhanced cellular proliferation in fibroblasts from rat pulmonary but not systemic arteries
    • Welsh D.J., Peacock A.J., MacClean M., and Harnett M. Chronic hypoxia induces constitutive p38 mitogen-activated protein kinase activity that correlated with enhanced cellular proliferation in fibroblasts from rat pulmonary but not systemic arteries. Am J Respir Crit Care Med 164 (2001) 282-289
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 282-289
    • Welsh, D.J.1    Peacock, A.J.2    MacClean, M.3    Harnett, M.4
  • 11
    • 0031783189 scopus 로고    scopus 로고
    • Hypoxic stimulation of the stress-activated protein kinases in pulmonary artery fibroblasts
    • Scott P.H., Paul A., Belham C.M., Peacock A.J., Wadsworth R.M., Gould G.W., et al. Hypoxic stimulation of the stress-activated protein kinases in pulmonary artery fibroblasts. Am J Crit Care Med 158 (1998) 958-962
    • (1998) Am J Crit Care Med , vol.158 , pp. 958-962
    • Scott, P.H.1    Paul, A.2    Belham, C.M.3    Peacock, A.J.4    Wadsworth, R.M.5    Gould, G.W.6
  • 12
    • 0034712939 scopus 로고    scopus 로고
    • Hypoxia-inducbile factor 1 alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
    • Sutter C.H., Laughner E., and Semenza G.L. Hypoxia-inducbile factor 1 alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. PNAS 97 74748-53 (2000)
    • (2000) PNAS , vol.97 , Issue.74748-53
    • Sutter, C.H.1    Laughner, E.2    Semenza, G.L.3
  • 13
    • 34548843992 scopus 로고    scopus 로고
    • Freshney, I.R., 1983. Culture of animal cells. New York: A.R. Liss.
  • 14
    • 0028988138 scopus 로고
    • SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin 1
    • Cuenda A., Rouse J., Doza Y.N., Meier R., Cohen P., Gallagher T.F., et al. SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin 1. FEBS Lett 364 (1995) 229
    • (1995) FEBS Lett , vol.364 , pp. 229
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6
  • 15
    • 0035844211 scopus 로고    scopus 로고
    • Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-medicated activation of mitogen-activated protein kinases
    • Das M., Bouschey D.M., Moore M.J., Hopkins D.C., Nemenoff R.A., and Stenmark K.R. Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-medicated activation of mitogen-activated protein kinases. J Biol Chem 276 19 (2001) 15631-15640
    • (2001) J Biol Chem , vol.276 , Issue.19 , pp. 15631-15640
    • Das, M.1    Bouschey, D.M.2    Moore, M.J.3    Hopkins, D.C.4    Nemenoff, R.A.5    Stenmark, K.R.6
  • 16
    • 0034117180 scopus 로고    scopus 로고
    • Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase C isozymes
    • Das M., Dempsey E.C., Bouchey D., Reyland M.E., and Stenmark K.R. Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase C isozymes. Am J Respir Cell Mol Biol 22 (2000) 15-25
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 15-25
    • Das, M.1    Dempsey, E.C.2    Bouchey, D.3    Reyland, M.E.4    Stenmark, K.R.5
  • 17
    • 20944432353 scopus 로고    scopus 로고
    • Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1 alpha and an autocrine angiotensis system
    • Krick S., Hanze J., Eul B., Savai R., Seay U., Grimminger F., et al. Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1 alpha and an autocrine angiotensis system. FASEB J 19 (2005) 857-859
    • (2005) FASEB J , vol.19 , pp. 857-859
    • Krick, S.1    Hanze, J.2    Eul, B.3    Savai, R.4    Seay, U.5    Grimminger, F.6
  • 18
    • 30144442801 scopus 로고    scopus 로고
    • p38 MAP kinase isoform activity and cell cycle regulators in the proliferative response of pulmonary and systemic artery fibroblasts to acute hypoxia
    • Welsh D.J., Scott P.H., and Peacock A.J. p38 MAP kinase isoform activity and cell cycle regulators in the proliferative response of pulmonary and systemic artery fibroblasts to acute hypoxia. Pulm Pharm Therapeut 19 (2006) 128-138
    • (2006) Pulm Pharm Therapeut , vol.19 , pp. 128-138
    • Welsh, D.J.1    Scott, P.H.2    Peacock, A.J.3
  • 19
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor-1
    • Semenza G.L. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor-1. Ann Rev Cell Dev Biol 15 (1999) 551-578
    • (1999) Ann Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 20
    • 5644285411 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infartion in the rat
    • See F., Thomas W., Way K., Tzanidis A., Kompa A., Lewis D., et al. p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infartion in the rat. J Am Coll Cardiol 44 (2004) 1679-1689
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1679-1689
    • See, F.1    Thomas, W.2    Way, K.3    Tzanidis, A.4    Kompa, A.5    Lewis, D.6
  • 21
  • 22
    • 16244362070 scopus 로고    scopus 로고
    • Stretch-induced cell proliferation is mediated by FAK-MAPK pathway
    • Wang J.G., Miyazu M., Xiang P., Li S.N., Sokabe M., and Naruse K. Stretch-induced cell proliferation is mediated by FAK-MAPK pathway. Life Sci 76 (2005) 2817-2825
    • (2005) Life Sci , vol.76 , pp. 2817-2825
    • Wang, J.G.1    Miyazu, M.2    Xiang, P.3    Li, S.N.4    Sokabe, M.5    Naruse, K.6
  • 23
    • 11144357130 scopus 로고    scopus 로고
    • Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts
    • Seto H., Kamekura S., Miura T., Yamamoto A., Chikuda H., Ogata T., et al. Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts. J Clin Invest 113 (2004) 718-726
    • (2004) J Clin Invest , vol.113 , pp. 718-726
    • Seto, H.1    Kamekura, S.2    Miura, T.3    Yamamoto, A.4    Chikuda, H.5    Ogata, T.6
  • 24
    • 0141866937 scopus 로고    scopus 로고
    • p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts
    • Furukawa F., Matsuzaki K., Mori S., Tahashi Y., Yoshida K., Sugano Y., et al. p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts. Hepatology 38 (2003) 879-889
    • (2003) Hepatology , vol.38 , pp. 879-889
    • Furukawa, F.1    Matsuzaki, K.2    Mori, S.3    Tahashi, Y.4    Yoshida, K.5    Sugano, Y.6
  • 25
    • 17144453009 scopus 로고    scopus 로고
    • Evidence for a role of MSK1 in transformimg growth factor-β-mediated responses through p38α and Smad signaling pathways
    • Abecassis L., Rogier E., Vazquez A., Atfi A., and Bourgeade M.F. Evidence for a role of MSK1 in transformimg growth factor-β-mediated responses through p38α and Smad signaling pathways. J Biol Chem 279 (2004) 30474-30479
    • (2004) J Biol Chem , vol.279 , pp. 30474-30479
    • Abecassis, L.1    Rogier, E.2    Vazquez, A.3    Atfi, A.4    Bourgeade, M.F.5
  • 26
    • 0036165251 scopus 로고    scopus 로고
    • Pharmacological inhibitors of MAPK pathways
    • English J.M., and Cobb M.H. Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci 23 1 (2002) 40-45
    • (2002) Trends Pharmacol Sci , vol.23 , Issue.1 , pp. 40-45
    • English, J.M.1    Cobb, M.H.2
  • 27
    • 0142026209 scopus 로고    scopus 로고
    • p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
    • Kumar S., Boehm J., and Lee J.C. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2 9 (2003) 717-726
    • (2003) Nat Rev Drug Discov , vol.2 , Issue.9 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.