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Volumn 2, Issue 4, 2012, Pages 392-402

Sodium iodide symporter for nuclear molecular imaging and gene ther-apy: From bedside to bench and back

Author keywords

Gene therapy; Molecular imaging; Radionuclide; Radionuclide based imaging; Sodium iodide symporter

Indexed keywords

ASTATINE 211; FLUORINE 18; IODINE 123; IODINE 124; IODINE 131; MEMBRANE PROTEIN; RADIOISOTOPE; RADIOPHARMACEUTICAL AGENT; RHENIUM 186; RHENIUM 188; SODIUM IODIDE SYMPORTER; TECHNETIUM 99M; TELLURIUM 123; UNCLASSIFIED DRUG; XENON 124;

EID: 84864538409     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.3722     Document Type: Review
Times cited : (101)

References (53)
  • 1
    • 33750269612 scopus 로고    scopus 로고
    • A perspective view of sodium iodide symporter research and its clinical implications
    • Riesco-Eizaguirre G, Santisteban P. A perspective view of sodium iodide symporter research and its clinical implications. Eur J Endocrinol. 2006; 155: 495-512.
    • (2006) Eur J Endocrinol , vol.155 , pp. 495-512
    • Riesco-Eizaguirre, G.1    Santisteban, P.2
  • 2
    • 78649693855 scopus 로고    scopus 로고
    • Update in thyroid imaging The expanding world of thyroid imaging and its translation to clinical practice
    • Soto GD, Halperin I, Squarcia M, Lomena F, Domingo MP. Update in thyroid imaging. The expanding world of thyroid imaging and its translation to clinical practice. Hormones (Athens). 2010; 9: 287-98.
    • (2010) Hormones (Athens) , vol.9 , pp. 287-298
    • Soto, G.D.1    Halperin, I.2    Squarcia, M.3    Lomena, F.4    Domingo, M.P.5
  • 3
    • 34547136188 scopus 로고    scopus 로고
    • Use of radiopharmaceuticals for diagnosis, treatment, and follow-up of differentiated thyroid carcinoma
    • Verburg FA, de Keizer B, van Isselt JW. Use of radiopharmaceuticals for diagnosis, treatment, and follow-up of differentiated thyroid carcinoma. Anticancer Agents Med Chem. 2007; 7: 399-409.
    • (2007) Anticancer Agents Med Chem , vol.7 , pp. 399-409
    • Verburg, F.A.1    de Keizer, B.2    van Isselt, J.W.3
  • 4
    • 0030053759 scopus 로고    scopus 로고
    • Cloning and characterization of the thyroid iodide transporter
    • Dai G, Levy O, Carrasco N. Cloning and characterization of the thyroid iodide transporter. Nature. 1996; 379: 458-60.
    • (1996) Nature , vol.379 , pp. 458-460
    • Dai, G.1    Levy, O.2    Carrasco, N.3
  • 5
    • 58849107795 scopus 로고    scopus 로고
    • Clinical testing of engineered oncolytic measles virus strains in the treatment of cancer: an overview
    • Msaouel P, Dispenzieri A, Galanis E. Clinical testing of engineered oncolytic measles virus strains in the treatment of cancer: an overview. Curr Opin Mol Ther. 2009; 11: 43-53.
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 43-53
    • Msaouel, P.1    Dispenzieri, A.2    Galanis, E.3
  • 6
    • 54749122110 scopus 로고    scopus 로고
    • Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate
    • Barton KN, Stricker H, Brown SL, Elshaikh M, Aref I, Lu M, et al. Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate. Mol Ther. 2008; 16: 1761-9.
    • (2008) Mol Ther , vol.16 , pp. 1761-1769
    • Barton, K.N.1    Stricker, H.2    Brown, S.L.3    Elshaikh, M.4    Aref, I.5    Lu, M.6
  • 7
    • 79851506251 scopus 로고    scopus 로고
    • Trafficking macrophage migration using reporter gene imaging with human sodium iodide symporter in animal models of inflammation
    • Seo JH, Jeon YH, Lee YJ, Yoon GS, Won DI, Ha JH, et al. Trafficking macrophage migration using reporter gene imaging with human sodium iodide symporter in animal models of inflammation. J Nucl Med. 2010; 51: 1637-43.
    • (2010) J Nucl Med , vol.51 , pp. 1637-1643
    • Seo, J.H.1    Jeon, Y.H.2    Lee, Y.J.3    Yoon, G.S.4    Won, D.I.5    Ha, J.H.6
  • 8
    • 77953715954 scopus 로고    scopus 로고
    • Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model
    • Ahn SJ, Jeon YH, Lee YJ, Lee YL, Lee SW, Ahn BC, et al. Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model. Cancer Gene Ther. 2010; 17: 492-500.
    • (2010) Cancer Gene Ther , vol.17 , pp. 492-500
    • Ahn, S.J.1    Jeon, Y.H.2    Lee, Y.J.3    Lee, Y.L.4    Lee, S.W.5    Ahn, B.C.6
  • 9
    • 78651312127 scopus 로고    scopus 로고
    • Human sodium iodide symporter added to multidrug resistance 1 small hairpin RNA in a single gene construct enhances the therapeutic effects of radioiodine in a nude mouse model of multidrug resistant colon cancer
    • Jeon YH, Ahn SJ, Lee YJ, Lee YL, Lee SW, Park SY, et al. Human sodium iodide symporter added to multidrug resistance 1 small hairpin RNA in a single gene construct enhances the therapeutic effects of radioiodine in a nude mouse model of multidrug resistant colon cancer. Cancer Biother Radiopharm. 2011; 25: 671-9.
    • (2011) Cancer Biother Radiopharm , vol.25 , pp. 671-679
    • Jeon, Y.H.1    Ahn, S.J.2    Lee, Y.J.3    Lee, Y.L.4    Lee, S.W.5    Park, S.Y.6
  • 10
    • 77249154543 scopus 로고    scopus 로고
    • Combined radionuclide-chemotherapy and in vivo imaging of hepatocellular carcinoma cells after transfection of a triple-gene construct, NIS, HSV1-sr39tk, and EGFP
    • Lee YL, Lee YJ, Ahn SJ, Choi TH, Moon BS, Cheon GJ, et al. Combined radionuclide-chemotherapy and in vivo imaging of hepatocellular carcinoma cells after transfection of a triple-gene construct, NIS, HSV1-sr39tk, and EGFP. Cancer Lett. 2010; 290: 129-38.
    • (2010) Cancer Lett , vol.290 , pp. 129-138
    • Lee, Y.L.1    Lee, Y.J.2    Ahn, S.J.3    Choi, T.H.4    Moon, B.S.5    Cheon, G.J.6
  • 12
    • 0037326161 scopus 로고    scopus 로고
    • The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance
    • Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, et al. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocr Rev. 2003; 24: 48-77.
    • (2003) Endocr Rev , vol.24 , pp. 48-77
    • Dohan, O.1    De la Vieja, A.2    Paroder, V.3    Riedel, C.4    Artani, M.5    Reed, M.6
  • 14
    • 0037683589 scopus 로고    scopus 로고
    • Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections
    • Wapnir IL, van de Rijn M, Nowels K, Amenta PS, Walton K, Montgomery K, et al. Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections. J Clin Endocrinol Metab. 2003; 88: 1880-8.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1880-1888
    • Wapnir, I.L.1    van de Rijn, M.2    Nowels, K.3    Amenta, P.S.4    Walton, K.5    Montgomery, K.6
  • 15
    • 77249133123 scopus 로고    scopus 로고
    • Visualization of gene expression in the live subject using the Na/I symporter as a reporter gene: applications in biotherapy
    • Baril P, Martin-Duque P, Vassaux G. Visualization of gene expression in the live subject using the Na/I symporter as a reporter gene: applications in biotherapy. Br J Pharmacol. 2010; 159: 761-71.
    • (2010) Br J Pharmacol , vol.159 , pp. 761-771
    • Baril, P.1    Martin-Duque, P.2    Vassaux, G.3
  • 16
    • 0036732003 scopus 로고    scopus 로고
    • Sodium iodide symporter: its role in nuclear medicine
    • Chung JK. Sodium iodide symporter: its role in nuclear medicine. J Nucl Med. 2002; 43: 1188-200.
    • (2002) J Nucl Med , vol.43 , pp. 1188-1200
    • Chung, J.K.1
  • 17
    • 79960978316 scopus 로고    scopus 로고
    • Combined Cerenkov luminescence and nuclear imaging of radioiodine in the thyroid gland and thyroid cancer cells expressing sodium iodide symporter: initial feasibility study
    • Jeong SY, Hwang MH, Kim JE, Kang S, Park JC, Yoo J, et al. Combined Cerenkov luminescence and nuclear imaging of radioiodine in the thyroid gland and thyroid cancer cells expressing sodium iodide symporter: initial feasibility study. Endocr J. 2011; 58: 575-83.
    • (2011) Endocr J , vol.58 , pp. 575-583
    • Jeong, S.Y.1    Hwang, M.H.2    Kim, J.E.3    Kang, S.4    Park, J.C.5    Yoo, J.6
  • 20
    • 77958483257 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of [(18)F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter
    • Jauregui-Osoro M, Sunassee K, Weeks AJ, Berry DJ, Paul RL, Cleij M, et al. Synthesis and biological evaluation of [(18)F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter. Eur J Nucl Med Mol Imaging. 2010; 37: 2108-16.
    • (2010) Eur J Nucl Med Mol Imaging , vol.37 , pp. 2108-2116
    • Jauregui-Osoro, M.1    Sunassee, K.2    Weeks, A.J.3    Berry, D.J.4    Paul, R.L.5    Cleij, M.6
  • 21
    • 34250754525 scopus 로고    scopus 로고
    • Transport of free 211At and 125I- in thyroid epithelial cells: effects of anion channel blocker 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid on apical efflux and cellular retention
    • Lindencrona U, Forssell-Aronsson E, Nilsson M. Transport of free 211At and 125I- in thyroid epithelial cells: effects of anion channel blocker 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid on apical efflux and cellular retention. Nucl Med Biol. 2007; 34: 523-30.
    • (2007) Nucl Med Biol , vol.34 , pp. 523-530
    • Lindencrona, U.1    Forssell-Aronsson, E.2    Nilsson, M.3
  • 22
    • 3042511545 scopus 로고    scopus 로고
    • Rhenium-188 and copper-67 radiopharmaceuticals for the treatment of bladder cancer
    • Frier M. Rhenium-188 and copper-67 radiopharmaceuticals for the treatment of bladder cancer. Mini Rev Med Chem. 2004; 4: 61-8.
    • (2004) Mini Rev Med Chem , vol.4 , pp. 61-68
    • Frier, M.1
  • 24
    • 0035451674 scopus 로고    scopus 로고
    • Advancements in cancer therapy with alpha-emitters: a review
    • Imam SK. Advancements in cancer therapy with alpha-emitters: a review. Int J Radiat Oncol Biol Phys. 2001; 51: 271-8.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 271-278
    • Imam, S.K.1
  • 25
    • 79957456974 scopus 로고    scopus 로고
    • Pulmonary aspergilloma mimicking metastasis from papillary thyroid cancer
    • Ahn BC, Lee SW, Lee J, Kim C. Pulmonary aspergilloma mimicking metastasis from papillary thyroid cancer. Thyroid. 2011; 21: 555-8.
    • (2011) Thyroid , vol.21 , pp. 555-558
    • Ahn, B.C.1    Lee, S.W.2    Lee, J.3    Kim, C.4
  • 27
    • 70349269866 scopus 로고    scopus 로고
    • Hybrid SPECT-CT and PET-CT imaging of differentiated thyroid carcinoma
    • Wong KK, Zarzhevsky N, Cahill JM, Frey KA, Avram AM. Hybrid SPECT-CT and PET-CT imaging of differentiated thyroid carcinoma. Br J Radiol. 2009; 82: 860-76.
    • (2009) Br J Radiol , vol.82 , pp. 860-876
    • Wong, K.K.1    Zarzhevsky, N.2    Cahill, J.M.3    Frey, K.A.4    Avram, A.M.5
  • 28
    • 79953797911 scopus 로고    scopus 로고
    • Applications of molecular imaging in drug discovery and development process
    • Ahn BC. Applications of molecular imaging in drug discovery and development process. Curr Pharm Biotechnol. 2011; 12: 459-68.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 459-468
    • Ahn, B.C.1
  • 29
    • 46749154311 scopus 로고    scopus 로고
    • Latest advances in molecular imaging instrumentation
    • Pichler BJ, Wehrl HF, Judenhofer MS. Latest advances in molecular imaging instrumentation. J Nucl Med. 2008; 49 Suppl 2: 5S-23S.
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Pichler, B.J.1    Wehrl, H.F.2    Judenhofer, M.S.3
  • 30
    • 79960050337 scopus 로고    scopus 로고
    • Total thyroidectomy in the mouse: the feasibility study in the non-thyroidal tumor model expressing human sodium/Iodide symporter gene
    • Shim HK, Kim SG, Kim TS, Kim SK, Lee SJ. Total thyroidectomy in the mouse: the feasibility study in the non-thyroidal tumor model expressing human sodium/Iodide symporter gene. Nucl Med Mol Imag. 2011; 45: 103-10.
    • (2011) Nucl Med Mol Imag , vol.45 , pp. 103-110
    • Shim, H.K.1    Kim, S.G.2    Kim, T.S.3    Kim, S.K.4    Lee, S.J.5
  • 32
    • 85047681191 scopus 로고    scopus 로고
    • Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer
    • Mazzaferri EL, Kloos RT. Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer. J Clin Endocrinol Metab. 2001; 86: 1447-63.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1447-1463
    • Mazzaferri, E.L.1    Kloos, R.T.2
  • 33
    • 84942483273 scopus 로고
    • Radioactive iodine therapy; effect on functioning metastases of adenocarcinoma of the thyroid
    • Seidlin SM, Marinelli LD, Oshry E. Radioactive iodine therapy; effect on functioning metastases of adenocarcinoma of the thyroid. J Am Med Assoc. 1946; 132: 838-47.
    • (1946) J Am Med Assoc , vol.132 , pp. 838-847
    • Seidlin, S.M.1    Marinelli, L.D.2    Oshry, E.3
  • 34
    • 70449370231 scopus 로고    scopus 로고
    • Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer
    • Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2009; 19: 1167-214.
    • (2009) Thyroid , vol.19 , pp. 1167-1214
    • Cooper, D.S.1    Doherty, G.M.2    Haugen, B.R.3    Kloos, R.T.4    Lee, S.L.5    Mandel, S.J.6
  • 35
    • 79958846735 scopus 로고    scopus 로고
    • Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists
    • Bahn Chair RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, et al. Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists. Thyroid. 2011; 21: 593-646.
    • (2011) Thyroid , vol.21 , pp. 593-646
    • Bahn Chair, R.S.1    Burch, H.B.2    Cooper, D.S.3    Garber, J.R.4    Greenlee, M.C.5    Klein, I.6
  • 36
    • 80455174021 scopus 로고    scopus 로고
    • Combined therapy with (131)I and retinoic acid in Korean patients with radioiodine-refractory papillary thyroid cancer
    • Oh SW, Moon SH, Park do J, Cho BY, Jung KC, Lee DS, et al. Combined therapy with (131)I and retinoic acid in Korean patients with radioiodine-refractory papillary thyroid cancer. Eur J Nucl Med Mol Imaging. 2011; 38: 1798-805.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 1798-1805
    • Oh, S.W.1    Moon, S.H.2    Park do, J.3    Cho, B.Y.4    Jung, K.C.5    Lee, D.S.6
  • 37
    • 0021717492 scopus 로고
    • I-131 total-body scan: localization of disseminated gastric adenocarcinoma Case report and survey of the literature
    • Wu SY, Kollin J, Coodley E, Lockyer T, Lyons KP, Moran E, et al. I-131 total-body scan: localization of disseminated gastric adenocarcinoma. Case report and survey of the literature. J Nucl Med. 1984; 25: 1204-9.
    • (1984) J Nucl Med , vol.25 , pp. 1204-1209
    • Wu, S.Y.1    Kollin, J.2    Coodley, E.3    Lockyer, T.4    Lyons, K.P.5    Moran, E.6
  • 38
    • 0033835541 scopus 로고    scopus 로고
    • The mammary gland iodide transporter is expressed during lactation and in breast cancer
    • Tazebay UH, Wapnir IL, Levy O, Dohan O, Zuckier LS, Zhao QH, et al. The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nat Med. 2000; 6: 871-8.
    • (2000) Nat Med , vol.6 , pp. 871-878
    • Tazebay, U.H.1    Wapnir, I.L.2    Levy, O.3    Dohan, O.4    Zuckier, L.S.5    Zhao, Q.H.6
  • 39
    • 0036425965 scopus 로고    scopus 로고
    • The sodium iodide symporter: its pathophysiological and therapeutic implications
    • Spitzweg C, Morris JC. The sodium iodide symporter: its pathophysiological and therapeutic implications. Clin Endocrinol (Oxf). 2002; 57: 559-74.
    • (2002) Clin Endocrinol (Oxf) , vol.57 , pp. 559-574
    • Spitzweg, C.1    Morris, J.C.2
  • 40
    • 0035487238 scopus 로고    scopus 로고
    • Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues
    • Moon DH, Lee SJ, Park KY, Park KK, Ahn SH, Pai MS, et al. Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues. Nucl Med Biol. 2001; 28: 829-34.
    • (2001) Nucl Med Biol , vol.28 , pp. 829-834
    • Moon, D.H.1    Lee, S.J.2    Park, K.Y.3    Park, K.K.4    Ahn, S.H.5    Pai, M.S.6
  • 41
    • 78650988085 scopus 로고    scopus 로고
    • Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of (1)(3)(1)I by carbamazepine in breast cancer cells
    • Willhauck MJ, DJ OK, Wunderlich N, Goke B, Spitzweg C. Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of (1)(3)(1)I by carbamazepine in breast cancer cells. Breast Cancer Res Treat. 2011; 125: 377-86.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 377-386
    • Willhauck, M.J.1    Dj, O.K.2    Wunderlich, N.3    Goke, B.4    Spitzweg, C.5
  • 42
    • 84859568542 scopus 로고    scopus 로고
    • Radioiodine therapy of thyroid carcinoma following Pax-8 gene transfer
    • doi:gt2011110 [pii] 10.1038/gt.2011.110
    • Mu D, Huang R, Ma X, Li S, Kuang A. Radioiodine therapy of thyroid carcinoma following Pax-8 gene transfer. Gene Ther. 2011; doi:gt2011110 [pii] 10.1038/gt.2011.110.
    • (2011) Gene Ther
    • Mu, D.1    Huang, R.2    Ma, X.3    Li, S.4    Kuang, A.5
  • 43
    • 20644433107 scopus 로고    scopus 로고
    • Effects of Pax8 and TTF-1 thyroid transcription factor gene transfer in hepatoma cells: imaging of functional protein-protein interaction and iodide uptake
    • Altmann A, Schulz RB, Glensch G, Eskerski H, Zitzmann S, Eisenhut M, et al. Effects of Pax8 and TTF-1 thyroid transcription factor gene transfer in hepatoma cells: imaging of functional protein-protein interaction and iodide uptake. J Nucl Med. 2005; 46: 831-9.
    • (2005) J Nucl Med , vol.46 , pp. 831-839
    • Altmann, A.1    Schulz, R.B.2    Glensch, G.3    Eskerski, H.4    Zitzmann, S.5    Eisenhut, M.6
  • 44
    • 77949271545 scopus 로고    scopus 로고
    • Wild-type p53 enhances the cytotoxic effect of radionuclide gene therapy using sodium iodide symporter in a murine anaplastic thyroid cancer model
    • Lee YJ, Chung JK, Kang JH, Jeong JM, Lee DS, Lee MC. Wild-type p53 enhances the cytotoxic effect of radionuclide gene therapy using sodium iodide symporter in a murine anaplastic thyroid cancer model. Eur J Nucl Med Mol Imaging. 2010; 37: 235-41.
    • (2010) Eur J Nucl Med Mol Imaging , vol.37 , pp. 235-241
    • Lee, Y.J.1    Chung, J.K.2    Kang, J.H.3    Jeong, J.M.4    Lee, D.S.5    Lee, M.C.6
  • 45
    • 0035132310 scopus 로고    scopus 로고
    • Similarities and differences between free 211At and 125I- transport in porcine thyroid epithelial cells cultured in bicameral chambers
    • Lindencrona U, Nilsson M, Forssell-Aronsson E. Similarities and differences between free 211At and 125I- transport in porcine thyroid epithelial cells cultured in bicameral chambers. Nucl Med Biol. 2001; 28: 41-50.
    • (2001) Nucl Med Biol , vol.28 , pp. 41-50
    • Lindencrona, U.1    Nilsson, M.2    Forssell-Aronsson, E.3
  • 46
    • 33644760432 scopus 로고    scopus 로고
    • Effective cancer therapy with the alpha-particle emitter [211At]astatine in a mouse model of genetically modified sodium/iodide symporter-expressing tumors
    • Petrich T, Quintanilla-Martinez L, Korkmaz Z, Samson E, Helmeke HJ, Meyer GJ, et al. Effective cancer therapy with the alpha-particle emitter [211At]astatine in a mouse model of genetically modified sodium/iodide symporter-expressing tumors. Clin Cancer Res. 2006; 12: 1342-8.
    • (2006) Clin Cancer Res , vol.12 , pp. 1342-1348
    • Petrich, T.1    Quintanilla-Martinez, L.2    Korkmaz, Z.3    Samson, E.4    Helmeke, H.J.5    Meyer, G.J.6
  • 47
    • 80455132123 scopus 로고    scopus 로고
    • Combined RNA Interference of Hexokinase II and I-131 human Sodium Iodide Symporter Gene Therapy in Anaplastic Thyroid Carcinoma
    • Kim J, Ahn BC, Hwang MH, Lee HW, Jeon YH, Jeong SY, et al. Combined RNA Interference of Hexokinase II and I-131 human Sodium Iodide Symporter Gene Therapy in Anaplastic Thyroid Carcinoma. J Nucl Med. 2011; 52: 1756-63.
    • (2011) J Nucl Med , vol.52 , pp. 1756-1763
    • Kim, J.1    Ahn, B.C.2    Hwang, M.H.3    Lee, H.W.4    Jeon, Y.H.5    Jeong, S.Y.6
  • 48
    • 2442440103 scopus 로고    scopus 로고
    • Cancer gene therapy: challenges and opportunities
    • Scanlon KJ. Cancer gene therapy: challenges and opportunities. Anticancer Res. 2004; 24: 501-4.
    • (2004) Anticancer Res , vol.24 , pp. 501-504
    • Scanlon, K.J.1
  • 49
    • 0041814617 scopus 로고    scopus 로고
    • Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells
    • Spitzweg C, Scholz IV, Bergert ER, Tindall DJ, Young CY, Goke B, et al. Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells. Endocrinology. 2003; 144: 3423-32.
    • (2003) Endocrinology , vol.144 , pp. 3423-3432
    • Spitzweg, C.1    Scholz, I.V.2    Bergert, E.R.3    Tindall, D.J.4    Young, C.Y.5    Goke, B.6
  • 51
    • 77956268881 scopus 로고    scopus 로고
    • Therapeutic effect of sodium iodide symporter gene therapy combined with external beam radiotherapy and targeted drugs that inhibit DNA repair
    • Hingorani M, White CL, Zaidi S, Pandha HS, Melcher AA, Bhide SA, et al. Therapeutic effect of sodium iodide symporter gene therapy combined with external beam radiotherapy and targeted drugs that inhibit DNA repair. Mol Ther. 2010; 18: 1599-605.
    • (2010) Mol Ther , vol.18 , pp. 1599-1605
    • Hingorani, M.1    White, C.L.2    Zaidi, S.3    Pandha, H.S.4    Melcher, A.A.5    Bhide, S.A.6
  • 52
    • 3042811612 scopus 로고    scopus 로고
    • The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid
    • Wapnir IL, Goris M, Yudd A, Dohan O, Adelman D, Nowels K, et al. The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid. Clin Cancer Res. 2004; 10: 4294-302.
    • (2004) Clin Cancer Res , vol.10 , pp. 4294-4302
    • Wapnir, I.L.1    Goris, M.2    Yudd, A.3    Dohan, O.4    Adelman, D.5    Nowels, K.6
  • 53
    • 84861979577 scopus 로고    scopus 로고
    • Effect of Parotid Gland Mas-sage on Parotid Gland Tc-99m pertechnetate Uptake
    • doi:10.1089/thy.2011-0188
    • Kim HW, Ahn BC, Lee SW, Lee J. Effect of Parotid Gland Mas-sage on Parotid Gland Tc-99m pertechnetate Uptake. Thyroid. 2012; doi:10.1089/thy.2011-0188.
    • (2012) Thyroid
    • Kim, H.W.1    Ahn, B.C.2    Lee, S.W.3    Lee, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.