메뉴 건너뛰기




Volumn 16, Issue 17, 2010, Pages 4363-4373

Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN P21; TRANSCRIPTION FACTOR SOX9;

EID: 77956251925     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-10-0138     Document Type: Article
Times cited : (115)

References (48)
  • 1
    • 44249086425 scopus 로고    scopus 로고
    • Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
    • Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008;83:584-94.
    • (2008) Mayo Clin Proc , vol.83 , pp. 584-594
    • Molina, J.R.1    Yang, P.2    Cassivi, S.D.3    Schild, S.E.4    Adjei, A.A.5
  • 2
    • 20444376137 scopus 로고    scopus 로고
    • Distribution according to histologic type and outcome by gender and age group in Taiwanese patients with lung carcinoma
    • Chen KY, Chang CH, Yu CJ, Kuo SH, Yang PC. Distribution according to histologic type and outcome by gender and age group in Taiwanese patients with lung carcinoma. Cancer 2005;103:2566-74.
    • (2005) Cancer , vol.103 , pp. 2566-2574
    • Chen, K.Y.1    Chang, C.H.2    Yu, C.J.3    Kuo, S.H.4    Yang, P.C.5
  • 3
    • 0037314429 scopus 로고    scopus 로고
    • A comparison of trends in the incidence rate of lung cancer by histological type in the Osaka Cancer Registry, Japan and in the Surveillance, Epidemiology and End Results Program, USA
    • Yoshimi I, Ohshima A, Ajiki W, Tsukuma H, Sobue T. A comparison of trends in the incidence rate of lung cancer by histological type in the Osaka Cancer Registry, Japan and in the Surveillance, Epidemiology and End Results Program, USA. Jpn J Clin Oncol 2003;33: 98-104.
    • (2003) Jpn J Clin Oncol , vol.33 , pp. 98-104
    • Yoshimi, I.1    Ohshima, A.2    Ajiki, W.3    Tsukuma, H.4    Sobue, T.5
  • 4
    • 34247095520 scopus 로고    scopus 로고
    • Lung cancer in never-smokers
    • Toh CK, Lim WT. Lung cancer in never-smokers. J Clin Pathol 2007; 60:337-40.
    • (2007) J Clin Pathol , vol.60 , pp. 337-340
    • Toh, C.K.1    Lim, W.T.2
  • 5
    • 0034655293 scopus 로고    scopus 로고
    • Adenocarcinoma of the lung in young patients: The M. D. Anderson experience
    • Liu NS, Spitz MR, Kemp BL, et al. Adenocarcinoma of the lung in young patients: the M. D. Anderson experience. Cancer 2000;88: 1837-41.
    • (2000) Cancer , vol.88 , pp. 1837-1841
    • Liu, N.S.1    Spitz, M.R.2    Kemp, B.L.3
  • 7
    • 0035923521 scopus 로고    scopus 로고
    • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
    • Bhattacharjee A, Richards WG, Staunton J, et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A 2001; 98:13790-5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13790-13795
    • Bhattacharjee, A.1    Richards, W.G.2    Staunton, J.3
  • 8
    • 33846011470 scopus 로고    scopus 로고
    • A five-gene signature and clinical outcome in non-small-cell lung cancer
    • Chen HY, Yu SL, Chen CH, et al. A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med 2007;356: 11-20.
    • (2007) N Engl J Med , vol.356 , pp. 11-20
    • Chen, H.Y.1    Yu, S.L.2    Chen, C.H.3
  • 9
    • 36049000444 scopus 로고    scopus 로고
    • Survival prediction of stage I lung adenocarcinomas by expression of 10 genes
    • Bianchi F, Nuciforo P, Vecchi M, et al. Survival prediction of stage I lung adenocarcinomas by expression of 10 genes. J Clin Invest 2007;117:3436-44.
    • (2007) J Clin Invest , vol.117 , pp. 3436-3444
    • Bianchi, F.1    Nuciforo, P.2    Vecchi, M.3
  • 10
    • 0036696817 scopus 로고    scopus 로고
    • Twenty pairs of sox: Extent, homology, and nomenclature of the mouse and human sox transcription factor gene families
    • Schepers GE, Teasdale RD, Koopman P. Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Dev Cell 2002;3:167-70.
    • (2002) Dev Cell , vol.3 , pp. 167-170
    • Schepers, G.E.1    Teasdale, R.D.2    Koopman, P.3
  • 11
    • 0034175998 scopus 로고    scopus 로고
    • Pairing SOX off: With partners in the regulation of embryonic development
    • Kamachi Y, Uchikawa M, Kondoh H. Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet 2000;16: 182-7.
    • (2000) Trends Genet , vol.16 , pp. 182-187
    • Kamachi, Y.1    Uchikawa, M.2    Kondoh, H.3
  • 12
    • 34748830336 scopus 로고    scopus 로고
    • Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors
    • Lefebvre V, Dumitriu B, Penzo-Mendez A, Han Y, Pallavi B. Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors. Int J Biochem Cell Biol 2007;39: 2195-214.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 2195-2214
    • Lefebvre, V.1    Dumitriu, B.2    Penzo-Mendez, A.3    Han, Y.4    Pallavi, B.5
  • 13
    • 33846834049 scopus 로고    scopus 로고
    • Transcriptional control of lung morphogenesis
    • Maeda Y, Dave V, Whitsett JA. Transcriptional control of lung morphogenesis. Physiol Rev 2007;87:219-44.
    • (2007) Physiol Rev , vol.87 , pp. 219-244
    • Maeda, Y.1    Dave, V.2    Whitsett, J.A.3
  • 14
    • 63149120518 scopus 로고    scopus 로고
    • The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer
    • Medina PP, Castillo SD, Blanco S, et al. The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer. Hum Mol Genet 2009;18:1343-52.
    • (2009) Hum Mol Genet , vol.18 , pp. 1343-1352
    • Medina, P.P.1    Castillo, S.D.2    Blanco, S.3
  • 15
    • 70350641014 scopus 로고    scopus 로고
    • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
    • Bass AJ, Watanabe H, Mermel CH, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 2009;41:1238-42.
    • (2009) Nat Genet , vol.41 , pp. 1238-1242
    • Bass, A.J.1    Watanabe, H.2    Mermel, C.H.3
  • 16
    • 13744257107 scopus 로고    scopus 로고
    • Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays
    • Yap YL, Lam DC, Luc G, et al. Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays. Nucleic Acids Res 2005;33:409-21.
    • (2005) Nucleic Acids Res , vol.33 , pp. 409-421
    • Yap, Y.L.1    Lam, D.C.2    Luc, G.3
  • 17
    • 34347209095 scopus 로고    scopus 로고
    • Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme
    • Su LJ, Chang CW, Wu YC, et al. Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. BMC Genomics 2007;8:140.
    • (2007) BMC Genomics , vol.8 , pp. 140
    • Su, L.J.1    Chang, C.W.2    Wu, Y.C.3
  • 18
    • 45749140422 scopus 로고    scopus 로고
    • Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival
    • Landi MT, Dracheva T, Rotunno M, et al. Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival. PLoS One 2008;3:e1651.
    • (2008) PLoS One , vol.3
    • Landi, M.T.1    Dracheva, T.2    Rotunno, M.3
  • 19
    • 45549109664 scopus 로고    scopus 로고
    • Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the modelbased background correction methodology
    • Ding LH, Xie Y, Park S, Xiao G, Story MD. Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the modelbased background correction methodology. Nucleic Acids Res 2008;36:e58.
    • (2008) Nucleic Acids Res , vol.36
    • Ding, L.H.1    Xie, Y.2    Park, S.3    Xiao, G.4    Story, M.D.5
  • 20
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative pcr and the 2-[Δ][Δ]CT method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative pcr and the 2-[Δ][Δ]CT method. Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 21
    • 68049133177 scopus 로고    scopus 로고
    • G(α)12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization
    • Liu SC, Jen YM, Jiang SS, et al. G(α)12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization. Cancer Res 2009;69:6122-30.
    • (2009) Cancer Res , vol.69 , pp. 6122-6130
    • Liu, S.C.1    Jen, Y.M.2    Jiang, S.S.3
  • 22
    • 41949100321 scopus 로고    scopus 로고
    • Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways
    • Lafont JE, Talma S, Hopfgarten C, Murphy CL. Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways. J Biol Chem 2008; 283:4778-86.
    • (2008) J Biol Chem , vol.283 , pp. 4778-4786
    • Lafont, J.E.1    Talma, S.2    Hopfgarten, C.3    Murphy, C.L.4
  • 23
    • 39749099347 scopus 로고    scopus 로고
    • The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer
    • Cheng F, McLaughlin PJ, Verderame MF, Zagon IS. The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer. Mol Cancer 2008;7:5.
    • (2008) Mol Cancer , vol.7 , pp. 5
    • Cheng, F.1    McLaughlin, P.J.2    Verderame, M.F.3    Zagon, I.S.4
  • 24
    • 0031226737 scopus 로고    scopus 로고
    • Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line
    • Chu YW, Yang PC, Yang SC, et al. Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line. Am J Respir Cell Mol Biol 1997;17:353-60.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 353-360
    • Chu, Y.W.1    Yang, P.C.2    Yang, S.C.3
  • 25
    • 0029977067 scopus 로고    scopus 로고
    • Sex reversal by loss of the C-terminal transactivation domain of human SOX9
    • Sudbeck P, Schmitz ML, Baeuerle PA, Scherer G. Sex reversal by loss of the C-terminal transactivation domain of human SOX9. Nat Genet 1996;13:230-2.
    • (1996) Nat Genet , vol.13 , pp. 230-232
    • Sudbeck, P.1    Schmitz, M.L.2    Baeuerle, P.A.3    Scherer, G.4
  • 26
    • 0028135336 scopus 로고
    • Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
    • Foster JW, Dominguez-Steglich MA, Guioli S, et al. Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene. Nature 1994;372:525-30.
    • (1994) Nature , vol.372 , pp. 525-530
    • Foster, J.W.1    Dominguez-Steglich, M.A.2    Guioli, S.3
  • 28
    • 0035996994 scopus 로고    scopus 로고
    • Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia
    • Piper K, Ball SG, Keeling JW, Mansoor S, Wilson DI, Hanley NA. Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia. Mech Dev 2002; 116:223-6.
    • (2002) Mech Dev , vol.116 , pp. 223-226
    • Piper, K.1    Ball, S.G.2    Keeling, J.W.3    Mansoor, S.4    Wilson, D.I.5    Hanley, N.A.6
  • 30
    • 33846673020 scopus 로고    scopus 로고
    • SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells
    • Wang H, McKnight NC, Zhang T, Lu ML, Balk SP, Yuan X. SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res 2007;67: 528-36.
    • (2007) Cancer Res , vol.67 , pp. 528-536
    • Wang, H.1    McKnight, N.C.2    Zhang, T.3    Lu, M.L.4    Balk, S.P.5    Yuan, X.6
  • 31
    • 3142669010 scopus 로고    scopus 로고
    • SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
    • Blache P, van de Wetering M, Duluc I, et al. SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. J Cell Biol 2004;166:37-47.
    • (2004) J Cell Biol , vol.166 , pp. 37-47
    • Blache, P.1    Van De Wetering, M.2    Duluc, I.3
  • 32
    • 35348813142 scopus 로고    scopus 로고
    • SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation
    • Passeron T, Valencia JC, Bertolotto C, et al. SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation. Proc Natl Acad Sci U S A 2007;104:13984-9.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13984-13989
    • Passeron, T.1    Valencia, J.C.2    Bertolotto, C.3
  • 33
    • 0037343473 scopus 로고    scopus 로고
    • Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors
    • Wehrli BM, Huang W, De Crombrugghe B, Ayala AG, Czerniak B. Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors. Hum Pathol 2003;34:263-9.
    • (2003) Hum Pathol , vol.34 , pp. 263-269
    • Wehrli, B.M.1    Huang, W.2    De Crombrugghe, B.3    Ayala, A.G.4    Czerniak, B.5
  • 34
    • 50049106706 scopus 로고    scopus 로고
    • Transcription factors involved in pancreas development are expressed in paediatric solid pseudopapillary tumours
    • Galmiche L, Sarnacki S, Verkarre V, et al. Transcription factors involved in pancreas development are expressed in paediatric solid pseudopapillary tumours. Histopathology 2008;53:318-24.
    • (2008) Histopathology , vol.53 , pp. 318-324
    • Galmiche, L.1    Sarnacki, S.2    Verkarre, V.3
  • 35
    • 40949145618 scopus 로고    scopus 로고
    • SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion
    • Wang H, Leav I, Ibaragi S, et al. SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res 2008;68:1625-30.
    • (2008) Cancer Res , vol.68 , pp. 1625-1630
    • Wang, H.1    Leav, I.2    Ibaragi, S.3
  • 36
    • 49249105861 scopus 로고    scopus 로고
    • Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells
    • Darido C, Buchert M, Pannequin J, et al. Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells. Cancer Res 2008;68: 4258-68.
    • (2008) Cancer Res , vol.68 , pp. 4258-4268
    • Darido, C.1    Buchert, M.2    Pannequin, J.3
  • 37
    • 58049208376 scopus 로고    scopus 로고
    • Analysis of SOX9 expression in colorectal cancer
    • Lu B, Fang Y, Xu J, et al. Analysis of SOX9 expression in colorectal cancer. Am J Clin Pathol 2008;130:897-904.
    • (2008) Am J Clin Pathol , vol.130 , pp. 897-904
    • Lu, B.1    Fang, Y.2    Xu, J.3
  • 38
    • 40549128662 scopus 로고    scopus 로고
    • SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms
    • Vidal VP, Ortonne N, Schedl A. SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms. J Cutan Pathol 2008;35:373-9.
    • (2008) J Cutan Pathol , vol.35 , pp. 373-379
    • Vidal, V.P.1    Ortonne, N.2    Schedl, A.3
  • 39
  • 40
    • 65249112671 scopus 로고    scopus 로고
    • Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid
    • Passeron T, Valencia JC, Namiki T, et al. Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. J Clin Invest 2009;119:954-63.
    • (2009) J Clin Invest , vol.119 , pp. 954-963
    • Passeron, T.1    Valencia, J.C.2    Namiki, T.3
  • 41
    • 13944260928 scopus 로고    scopus 로고
    • Normal lung development and function after Sox9 inactivation in the respiratory epithelium
    • Perl AK, Kist R, Shan Z, Scherer G, Whitsett JA. Normal lung development and function after Sox9 inactivation in the respiratory epithelium. Genesis 2005;41:23-32.
    • (2005) Genesis , vol.41 , pp. 23-32
    • Perl, A.K.1    Kist, R.2    Shan, Z.3    Scherer, G.4    Whitsett, J.A.5
  • 42
    • 49449105336 scopus 로고    scopus 로고
    • Lung epithelial progenitor cells: Lessons from development
    • Rawlins EL. Lung epithelial progenitor cells: lessons from development. Proc Am Thorac Soc 2008;5:675-81.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 675-681
    • Rawlins, E.L.1
  • 43
    • 0034060638 scopus 로고    scopus 로고
    • Relevance of proliferative and pro-apoptotic factors in non-small-cell lung cancer for patient survival
    • Volm M, Koomagi R. Relevance of proliferative and pro-apoptotic factors in non-small-cell lung cancer for patient survival. Br J Cancer 2000;82:1747-54.
    • (2000) Br J Cancer , vol.82 , pp. 1747-1754
    • Volm, M.1    Koomagi, R.2
  • 44
    • 0032516632 scopus 로고    scopus 로고
    • A study on p16, pRb, cdk4 and cyclinD1 expression in non-small cell lung cancers
    • Lingfei K, Pingzhang Y, Zhengguo L, Jianhua G, Yaowu Z. A study on p16, pRb, cdk4 and cyclinD1 expression in non-small cell lung cancers. Cancer Lett 1998;130:93-101.
    • (1998) Cancer Lett , vol.130 , pp. 93-101
    • Lingfei, K.1    Pingzhang, Y.2    Zhengguo, L.3    Jianhua, G.4    Yaowu, Z.5
  • 45
    • 0037106265 scopus 로고    scopus 로고
    • Clinical significance of p21 expression in non-small-cell lung cancer
    • Shoji T, Tanaka F, Takata T, et al. Clinical significance of p21 expression in non-small-cell lung cancer. J Clin Oncol 2002;20: 3865-71.
    • (2002) J Clin Oncol , vol.20 , pp. 3865-3871
    • Shoji, T.1    Tanaka, F.2    Takata, T.3
  • 46
    • 0037028208 scopus 로고    scopus 로고
    • Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models
    • Jackson RJ, Adnane J, Coppola D, Cantor A, Sebti SM, Pledger WJ. Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models. Oncogene 2002;21: 8486-97.
    • (2002) Oncogene , vol.21 , pp. 8486-8497
    • Jackson, R.J.1    Adnane, J.2    Coppola, D.3    Cantor, A.4    Sebti, S.M.5    Pledger, W.J.6
  • 47
    • 44449178497 scopus 로고    scopus 로고
    • Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer
    • Kwei KA, Kim YH, Girard L, et al. Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Oncogene 2008;27:3635-40.
    • (2008) Oncogene , vol.27 , pp. 3635-3640
    • Kwei, K.A.1    Kim, Y.H.2    Girard, L.3
  • 48
    • 36248980204 scopus 로고    scopus 로고
    • Characterizing the cancer genome in lung adenocarcinoma
    • Weir BA, Woo MS, Getz G, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature 2007;450:893-8.
    • (2007) Nature , vol.450 , pp. 893-898
    • Weir, B.A.1    Woo, M.S.2    Getz, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.