Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis

Annals of the Rheumatic Diseases

Volumn 69, Issue 8, 2010, Pages 1495-1501

  Frey, Oliver ^a   Meisel, Juliane ^a   Hutloff, Andreas ^b,c   Bonhagen, Kerstin ^a   Bruns, Lisa ^a   Kroczek, Richard A ^b   Morawietz, Lars ^d   Kamradt, Thomas ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLUCOSE 6 PHOSPHATE ISOMERASE; INDUCIBLE COSTIMULATOR PROTEIN; INTERLEUKIN 17; MONOCLONAL ANTIBODY; REGULATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTHRITIS; ARTICLE; AUTOIMMUNE ARTHRITIS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH17 CELL;

ANIMALS; ANTIBODIES, BLOCKING; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; CELL DIFFERENTIATION; CYTOKINES; GLUCOSE-6-PHOSPHATE; IMMUNOGLOBULINS; INTERLEUKIN-17; LIGANDS; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MICE; MICE, INBRED DBA; PROTEINS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TH1 CELLS;

EID: 77955458613     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2009.119164     Document Type: Article

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