In vitro biocompatibility of thermally gelling liquid mucoadhesive loaded curcuminoids in colorectal cancer chemoprevention

International Journal of Colorectal Disease

Volumn 27, Issue 7, 2012, Pages 869-878

  Chen, Ming Jenn ^a   Cheng, Ya Min ^b   Lai, Pei Heng ^c   Wu, June Fu ^d   Hsu, Yi Chiang ^e  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b Institute of Molecular and Cellular Biology   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

^e Graduate Institute of Medical Science   (Taiwan)

Author keywords

Apoptosis; Chemoprevention; Colorectal cancer; Curcuminoids; Thermogelling mucoadhesive polymer

Indexed keywords

ANTINEOPLASTIC AGENT; CURCUMINOID DERIVATIVE; GELLING AGENT; POLOXAMER; POLYMER; THERMOGELLING MUCOADHESIVE POLYMER; UNCLASSIFIED DRUG;

ADULT; AGED; APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER PREVENTION; CLINICAL ARTICLE; COLORECTAL CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; FEMALE; FLOW KINETICS; GELATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTESTINE MUCOSA; MALE; MUCOADHESIVE STRENGTH; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; PRIORITY JOURNAL; SUPPOSITORY; TEMPERATURE DEPENDENCE;

ADHESIVES; AGED; AGED, 80 AND OVER; BIOCOMPATIBLE MATERIALS; CELL DEATH; CELL SURVIVAL; CHEMOPREVENTION; COLORECTAL NEOPLASMS; CURCUMIN; DRUG DELIVERY SYSTEMS; FEMALE; GELS; HUMANS; INTESTINAL MUCOSA; MALE; MATERIALS TESTING; MIDDLE AGED; POLOXAMER; SUPPOSITORIES; TEMPERATURE;

EID: 84864445485     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-011-1393-3     Document Type: Article

References (25)

1. OK Ray A (2005) Cancer preventive role of selected dietary factors. Indian J Cancer 42:15-24
2. OK Khor TO, Keum YS, Lin W et al (2006) Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice. Cancer Res 66:613-621
3. OK Hsu YC, Weng HC, Lin S, Chien YW (2007) Curcuminoidscellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis. J Agric Food Chem 55:8213-8222
4. OK Lin YT, Wang LF, Hsu YC (2009) Curcuminoids suppress the growth of pharynx and nasopharyngeal carcinoma cells through induced apoptosis. J Agric Food Chem 57:3765-3770
5. Sinha R, Anderson DE, McDonald SS, Greenwald P (2003) Cancer risk and diet in India. J Postgrad Med 49:222-228
6. Perkins S, Verschoyle RD, Hill K et al (2002) Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis. Cancer Epidemiol Biomarkers Prev 11:535-540
7. Marczylo TH, Steward WP, Gescher AJ (2009) Rapid analysis of curcumin and curcumin metabolites in rat biomatrices using a novel ultraperformance liquid chromatography UPLC method. J Agric Food Chem 57:797-803
8. OK Inoue K, Nomura C, Ito S, Nagatsu A, Hino T, Oka H (2008) Purification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin by high-speed countercurrent chromatography. J Agric Food Chem 56:9328-9336
9. Wichitnithad W, Jongaroonngamsang N, Pummangura S, Rojsitthisak P (2009) A simple isocratic HPLC method for the simultaneous determination of curcuminoids in commercial turmeric extracts. Phytochem Anal 20:314-319
10. OK Yang KY, Lin LC, Tseng TY, Wang SC, Tsai TH (2007) Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 853:183-189
11. Sharma RA, Steward WP, Gescher AJ (2007) Pharmacokinetics and pharmacodynamics of curcumin. Adv Exp Med Biol 595:453-470
12. Chearwae W, Anuchapreeda S, Nandigama K, Ambudkar SV, Limtrakul P (2004) Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. Biochem Pharmacol 68:2043-2052
13. OK Shibata H, Yamakoshi H, Sato A et al (2009) Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo. Cancer Sci 100:956-960
14. OK Yadav VR, Suresh S, Devi K, Yadav S (2009) Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease. J Pharm Pharmacol 61:311-321
15. OK Harris LR, Roberts L (2008) Treatments for irritable bowel syndrome: patients' attitudes and acceptability. BMC Complement Altern Med 8:65
16. OK El-Kamel A, El-Khatib M (2006) Thermally reversible in situ gelling carbamazepine liquid suppository. Drug Deliv 13:143-148
17. OK Uzunkaya G, Bergişadi N (2003) In vitro drug liberation and kinetics of sustained release indomethacin suppository. Farmaco 58:509-512
18. Yong CS, Oh YK, Kim YI et al (2005) Physicochemical characterization and in vivo evaluation of poloxamer-based solid suppository containing diclofenac sodium in rats. Int J Pharm 301:54-61
19. OK Chen Y, Li G, Huang JG, Wang RH, Liu H, Tang R (2009) Comparison of self-microemulsifying drug delivery system versus solid dispersion technology used in the improvement of dissolution rate and bioavailability of vinpocetine. Yao Xue Xue Bao 44:658-666
20. OK Gelperina S, Maksimenko O, Khalansky A et al (2010) Drug delivery to the brain using surfactant-coated poly(lactide-coglycolide) nanoparticles: influence of the formulation parameters. Eur J Pharm Biopharm 74:157-163
21. OK Paek SH, Xuan JJ, Choi HG et al (2006) Poloxamer 188 and propylene glycol-based rectal suppository enhances anticancer effect of 5-fluorouracil in mice. Biol Pharm Bull 29:1060-1063
22. OK Koffi AA, Agnely F, Ponchel G, Grossiord JL (2006) Modulation of the rheological and mucoadhesive properties of thermosensitive poloxamer-based hydrogels intended for the rectal administration of quinine. Eur J Pharm Sci 27:328-335
23. OK Chen MJ, Lin YW, Cheng YM et al (2011) Early experimental results of colorectal carcinoma chemotherapeutics by liposomal curcuminoids. Dig J Nanomater BIOS 6:1445-1456
24. Huang TY, Hsu CW, Chang WC et al (2012) Demethoxycurcumin (DMC) retards cell growth, and induces apoptosis in human brain malignant glioma GBM 8401 cells. eCAM (in press)
25. OK Chien YW, Lin S (2002) Optimisation of treatment by applying programmable rate-controlled drug delivery technology. Clin Pharmacokinet 41:1267-1299