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Volumn 10, Issue 6, 2011, Pages 267-275

Myeloperoxidase and free iron levels: Potential biomarkers for early detection and prognosis of ovarian cancer

Author keywords

biomarkers; free iron; Myeloperoxidase; ovarian cancer

Indexed keywords

BIOLOGICAL MARKER; IRON; MYELOPEROXIDASE;

EID: 84864445472     PISSN: 15740153     EISSN: 18758592     Source Type: Journal    
DOI: 10.3233/CBM-2012-0255     Document Type: Article
Times cited : (28)

References (50)
  • 1
    • 33645526144 scopus 로고    scopus 로고
    • Cancer statistics 2006
    • Jemal, A., et al., Cancer statistics, 2006. CA Cancer J Clin, 2006. 56(2): Pp. 106-30.
    • (2006) CA Cancer J. Clin. , vol.56 , Issue.2 , pp. 106-130
    • Jemal, A.1
  • 2
    • 77957261196 scopus 로고    scopus 로고
    • Are serum protein biomarkers effective in Detecting ovarian cancer in its early stages
    • Leahy, Y., Are serum protein biomarkers effective in Detecting ovarian cancer in its early stages? Clin J Oncol Nurs, 2009. 13(4): Pp. 443-5.
    • (2009) Clin J. Oncol. Nurs. , vol.13 , Issue.4 , pp. 443-445
    • Leahy, Y.1
  • 3
    • 13944263971 scopus 로고    scopus 로고
    • Screening for ovarian cancer: Recommendation statement U.S
    • Screening for ovarian cancer: Recommendation statement U.S. Preventive Services Task Force. Am Fam Physician, 2005. 71(4): Pp. 759-62.
    • (2005) Preventive Services Task Force Am Fam Physician , vol.71 , Issue.4 , pp. 759-762
  • 4
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow
    • Balkwill, F. and A.Mantovani, Inflammation and cancer: back to Virchow? Lancet, 2001. 357(9255): Pp. 539-45.
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 5
    • 0033199807 scopus 로고    scopus 로고
    • Possible role of ovarian epithelial inflammation in ovarian cancer
    • Ness, R.B. and C. Cottreau, Possible role of ovarian epithelial inflammation in ovarian cancer. J Natl Cancer Inst, 1999. 91(17): Pp. 1459-67.
    • (1999) J. Natl. Cancer Inst. , vol.91 , Issue.17 , pp. 1459-1467
    • Ness, R.B.1    Cottreau, C.2
  • 6
    • 54549109936 scopus 로고    scopus 로고
    • Modulation of the antitumor immune response by complement
    • Markiewski, M.M., et al., Modulation of the antitumor immune response by complement. Nat Immunol, 2008. 9(11): pp. 1225-35.
    • (2008) Nat. Immunol , vol.9 , Issue.11 , pp. 1225-1235
    • Markiewski, M.M.1
  • 7
    • 0028196674 scopus 로고
    • Inflammation chromosomal instability, and cancer: The schistosomiasis model
    • Rosin, M.P., Anwar, W.A. and A.J.Ward, Inflammation, chromosomal instability, and cancer: The schistosomiasis model. Cancer Res, 1994. 54(7 Suppl): Pp. 1929s-1933s.
    • (1994) Cancer Res. , vol.54 , Issue.7 SUPPL.
    • Rosin, M.P.1    Anwar, W.A.2    Ward, A.J.3
  • 8
    • 0032701646 scopus 로고    scopus 로고
    • Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
    • Podrez, E.A., et al., Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J Clin Invest, 1999. 103(11): Pp. 1547-60.
    • (1999) J. Clin. Invest , vol.103 , Issue.11 , pp. 1547-1560
    • Podrez, E.A.1
  • 9
    • 0023484632 scopus 로고
    • Role of inflammatory cells in themetabolic activation of polycyclic aromatic hydrocarbons in mouse skin
    • Kensler, T.W., et al., Role of inflammatory cells in themetabolic activation of polycyclic aromatic hydrocarbons in mouse skin. Toxicol Appl Pharmacol, 1987. 90(2): Pp. 337-46.
    • (1987) Toxicol. Appl. Pharmacol. , vol.90 , Issue.2 , pp. 337-346
    • Kensler, T.W.1
  • 10
    • 73949126355 scopus 로고    scopus 로고
    • Myeloperoxidase serves as a redox switch that regulates apoptosis in epithelial ovarian cancer
    • Saed, G.M., et al., Myeloperoxidase serves as a redox switch that regulates apoptosis in epithelial ovarian cancer. Gynecol Oncol, 2010. 116(2): Pp. 276-81.
    • (2010) Gynecol. Oncol. , vol.116 , Issue.2 , pp. 276-281
    • Saed, G.M.1
  • 11
    • 67649846296 scopus 로고    scopus 로고
    • Myeloperoxidase interactionwith peroxynitrite: Chloride Deficiency and heme Depletion
    • Galijasevic, S., et al.,Myeloperoxidase interactionwith peroxynitrite: Chloride Deficiency and heme Depletion. Free Radic Biol Med, 2009. 47(4): Pp. 431-9.
    • (2009) Free. Radic. Biol. Med. , vol.47 , Issue.4 , pp. 431-439
    • Galijasevic, S.1
  • 12
    • 79955475052 scopus 로고    scopus 로고
    • Melatonin canmediate its vascular protective effect bymodulating free iron level by inhibiting hypochlorous acid-mediated hemoprotein heme Destruction
    • author reply e23
    • Maitra, D., et al.,Melatonin canmediate its vascular protective effect bymodulating free iron level by inhibiting hypochlorous acid-mediated hemoprotein heme Destruction. Hypertension, 2011. 57(5): P. e22; author reply e23.
    • (2011) Hypertension , vol.57 , Issue.5
    • Maitra, D.1
  • 13
    • 79959340510 scopus 로고    scopus 로고
    • Reaction of hemoglobin with HOCl: Mechanism of heme Destruction and free iron release
    • Maitra, D., et al., Reaction of hemoglobin with HOCl: Mechanism of heme Destruction and free iron release. Free Radic Biol Med, 2011. 51(2): Pp. 374-86.
    • (2011) Free. Radic. Biol. Med. , vol.51 , Issue.2 , pp. 374-386
    • Maitra, D.1
  • 14
    • 79959345072 scopus 로고    scopus 로고
    • Mechanism of hypochlorous acid-mediated heme Destruction and free iron release
    • Maitra, D., et al., Mechanism of hypochlorous acid-mediated heme Destruction and free iron release. Free Radic Biol Med, 2011. 51(2): Pp. 364-73.
    • (2011) Free. Radic. Biol. Med. , vol.51 , Issue.2 , pp. 364-373
    • Maitra, D.1
  • 15
    • 0034114830 scopus 로고    scopus 로고
    • Wound collagen Deposition in rats: Effects of an NO-NSAID and a selective COX-2 inhibitor
    • Muscara, M.N., et al., Wound collagen Deposition in rats: Effects of an NO-NSAID and a selective COX-2 inhibitor. Br J Pharmacol, 2000. 129(4): Pp. 681-6.
    • (2000) Br J. Pharmacol , vol.129 , Issue.4 , pp. 681-686
    • Muscara, M.N.1
  • 16
    • 0034900922 scopus 로고    scopus 로고
    • The role of iNOS in wound healing
    • Shi, H.P., et al., The role of iNOS in wound healing. Surgery, 2001. 130(2): Pp. 225-9.
    • (2001) Surgery , vol.130 , Issue.2 , pp. 225-229
    • Shi, H.P.1
  • 17
    • 0036227477 scopus 로고    scopus 로고
    • Role of nitric oxide in wound repair
    • Witte, M.B. and A. Barbul, Role of nitric oxide in wound repair. Am J Surg, 2002. 183(4): Pp. 406-12.
    • (2002) Am J. Surg. , vol.183 , Issue.4 , pp. 406-412
    • Witte, M.B.1    Barbul, A.2
  • 18
    • 0021711640 scopus 로고
    • Hemoglobin. A biologic fenton reagent
    • Sadrzadeh, S.M., et al., Hemoglobin. A biologic fenton reagent. J Biol Chem, 1984. 259(23): Pp. 14354-6.
    • (1984) J. Biol. Chem. , vol.259 , Issue.23 , pp. 14354-14356
    • Sadrzadeh, S.M.1
  • 19
    • 67949097437 scopus 로고    scopus 로고
    • Beyond CA125: The coming of age of ovarian cancer biomarkers. Are we there yet
    • Sasaroli, D., Coukos, G. and N. Scholler, Beyond CA125: The coming of age of ovarian cancer biomarkers. Are we there yet? Biomark Med, 2009. 3(3): Pp. 275-288.
    • (2009) Biomark Med. , vol.3 , Issue.3 , pp. 275-288
    • Sasaroli, D.1    Coukos, G.2    Scholler, N.3
  • 20
    • 0032848246 scopus 로고    scopus 로고
    • Comparative hybridization of an array of 21 500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas
    • Schummer, M., et al., Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene, 1999. 238(2): Pp. 375-85.
    • (1999) Gene. , vol.238 , Issue.2 , pp. 375-385
    • Schummer, M.1
  • 21
    • 16844374909 scopus 로고    scopus 로고
    • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
    • Drapkin, R., et al., Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res, 2005. 65(6): p. 2162-9.
    • (2005) Cancer Res. , vol.65 , Issue.6 , pp. 2162-2169
    • Drapkin, R.1
  • 22
    • 13844256742 scopus 로고    scopus 로고
    • Distinction between serous tumors of low malignant potential and serous carcinomas based on global mRNA expression profiling
    • Gilks, C.B., et al., Distinction between serous tumors of low malignant potential and serous carcinomas based on global mRNA expression profiling. Gynecol Oncol, 2005. 96(3): pp. 684-94.
    • (2005) Gynecol Oncol. , vol.96 , Issue.3 , pp. 684-694
    • Gilks, C.B.1
  • 23
    • 0033693082 scopus 로고    scopus 로고
    • Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer
    • Hough, C.D., et al., Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer. Cancer Res, 2000. 60(22): Pp. 6281-7.
    • (2000) Cancer Res. , vol.60 , Issue.22 , pp. 6281-6287
    • Hough, C.D.1
  • 24
    • 33646886778 scopus 로고    scopus 로고
    • Comprehensive analysis of HE4 expression in normal and malignant human tissues
    • Galgano, M.T., Hampton, G.M. and H.F. Frierson, Jr., Comprehensive analysis of HE4 expression in normal and malignant human tissues. Mod Pathol, 2006. 19(6): Pp. 847-53.
    • (2006) Mod. Pathol. , vol.19 , Issue.6 , pp. 847-853
    • Galgano, M.T.1    Hampton, G.M.2    Frierson Jr, H.F.3
  • 25
    • 31544471830 scopus 로고    scopus 로고
    • Proteins with whey-acidic-protein motifs and cancer
    • Bouchard, D., et al., Proteins with whey-acidic-protein motifs and cancer. Lancet Oncol, 2006. 7(2): Pp. 167-74.
    • (2006) Lancet Oncol. , vol.7 , Issue.2 , pp. 167-174
    • Bouchard, D.1
  • 26
    • 27144489497 scopus 로고    scopus 로고
    • Potential markers that complement expression of CA125 in epithelial ovarian cancer
    • Rosen, D.G., et al., Potential markers that complement expression of CA125 in epithelial ovarian cancer. Gynecol Oncol, 2005. 99(2): Pp. 267-77.
    • (2005) Gynecol Oncol. , vol.99 , Issue.2 , pp. 267-277
    • Rosen, D.G.1
  • 27
    • 33646240850 scopus 로고    scopus 로고
    • Bead-based ELISA for validation of ovarian cancer early Detection markers
    • Scholler, N., et al., Bead-based ELISA for validation of ovarian cancer early Detection markers. Clin Cancer Res, 2006. 12(7 Pt 1): Pp. 2117-24.
    • (2006) Clin. Cancer Res. , vol.12 , Issue.7 PART 1 , pp. 2117-2124
    • Scholler, N.1
  • 28
    • 38649134531 scopus 로고    scopus 로고
    • The use of multiple novel tumor biomarkers for the Detection of ovarian carcinoma in patients with a pelvic mass
    • Moore, R.G., et al., The use of multiple novel tumor biomarkers for the Detection of ovarian carcinoma in patients with a pelvic mass. Gynecol Oncol, 2008. 108(2): Pp. 402-8.
    • (2008) Gynecol Oncol , vol.108 , Issue.2 , pp. 402-408
    • Moore, R.G.1
  • 29
    • 0037012469 scopus 로고    scopus 로고
    • Osteopontin as a potential diagnostic biomarker for ovarian cancer
    • Kim, J.H., et al., Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA, 2002. 287(13): Pp. 1671-9.
    • (2002) JAMA , vol.287 , Issue.13 , pp. 1671-1769
    • Kim, J.H.1
  • 30
    • 32944462043 scopus 로고    scopus 로고
    • Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer
    • Menon, U., et al., Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer. J Clin Oncol, 2005. 23(31): Pp. 7919-26.
    • (2005) J. Clin. Oncol , vol.23 , Issue.31 , pp. 7919-7926
    • Menon, U.1
  • 31
    • 0028256236 scopus 로고
    • OVX1 as a marker for early stage endometrial carcinoma
    • Xu, F., et al., OVX1 as a marker for early stage endometrial carcinoma. Cancer, 1994. 73(1): Pp. 1855-8.
    • (1994) Cancer , vol.73 , Issue.1 , pp. 1855-1858
    • Xu, F.1
  • 32
    • 50149117364 scopus 로고    scopus 로고
    • Evaluation of biomarker panels for early stage ovarian cancer Detection andmonitoring for disease recurrence
    • Havrilesky, L.J., et al., Evaluation of biomarker panels for early stage ovarian cancer Detection andmonitoring for disease recurrence. Gynecol Oncol, 2008. 110(3): Pp. 374-82.
    • (2008) Gynecol Oncol , vol.110 , Issue.3 , pp. 374-382
    • Havrilesky, L.J.1
  • 33
    • 43849102348 scopus 로고    scopus 로고
    • Myeloperoxidase: A new biomarker of inflammation in ischemic heart disease and acute coronary syndromes
    • Loria, V., et al., Myeloperoxidase: A new biomarker of inflammation in ischemic heart disease and acute coronary syndromes. Mediators Inflamm, 2008. 2008: P. 135625.
    • (2008) Mediators Inflamm , vol.2008 , pp. 135625
    • Loria, V.1
  • 34
    • 0037058697 scopus 로고    scopus 로고
    • Myeloperoxidase (MPO) genotype and lung cancer histologic types: The MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers
    • Dally, H., et al., Myeloperoxidase (MPO) genotype and lung cancer histologic types: The MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers. Int J Cancer, 2002. 102(5): Pp. 530-5.
    • (2002) Int J. Cancer , vol.102 , Issue.5 , pp. 530-535
    • Dally, H.1
  • 35
    • 0029999154 scopus 로고    scopus 로고
    • An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormoneretinoic acid response element
    • Piedrafita, F.J., et al., An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormoneretinoic acid response element. J Biol Chem, 1996. 271(24): pp. 14412-20.
    • (1996) J. Biol. Chem. , vol.271 , Issue.24 , pp. 14412-14420
    • Piedrafita, F.J.1
  • 36
    • 0027292790 scopus 로고
    • Tyrosyl radical generated by myeloper oxidase catalyzes the oxidative cross-linking of proteins
    • Heinecke, J.W., et al., Tyrosyl radical generated by myeloper oxidase catalyzes the oxidative cross-linking of proteins. J Clin Invest, 1993. 91(6): Pp. 2866-72.
    • (1993) J. Clin. Invest , vol.91 , Issue.6 , pp. 2866-2872
    • Heinecke, J.W.1
  • 37
    • 21044448206 scopus 로고    scopus 로고
    • Association ofmyeloperoxidase promotor polymorphism with cirrhosis in patients with hereditary hemochromatosis
    • Osterreicher, C.H., et al., Association ofmyeloperoxidase promotor polymorphism with cirrhosis in patients with hereditary hemochromatosis. J Hepatol, 2005. 42(6): Pp. 914-9.
    • (2005) J. Hepatol , vol.42 , Issue.6 , pp. 914-919
    • Osterreicher, C.H.1
  • 38
    • 47249156127 scopus 로고    scopus 로고
    • Iron intake, Oxidative stress-related genes MnSOD and MPO) and prostate cancer risk in CARET cohort
    • Choi, J.Y., et al., Iron intake, oxidative stress-related genes MnSOD and MPO) and prostate cancer risk in CARET cohort. Carcinogenesis, 2008. 29(5): Pp. 964-70.
    • (2008) Carcinogenesis , vol.29 , Issue.5 , pp. 964-970
    • Choi, J.Y.1
  • 39
    • 3242700450 scopus 로고    scopus 로고
    • Iron nitric oxide, and myeloperoxidase in asthmatic patients
    • Ekmekci, O.B., et al., Iron, nitric oxide, and myeloperoxidase in asthmatic patients. Biochemistry (Mosc), 2004. 69(4): pp. 462-7.
    • (2004) Biochemistry (Mosc , vol.69 , Issue.4 , pp. 462-467
    • Ekmekci, O.B.1
  • 40
    • 84872219572 scopus 로고    scopus 로고
    • Serum Iron.Available from
    • Serum Iron. Serum Iron 2006; Available from: http://uimc. discoveryhospital.com/main.php?id=1456.
    • (2006) Serum Iron
  • 41
    • 84872208328 scopus 로고    scopus 로고
    • Medline Available from
    • Medline, Serum Iron. Serum Iron 2010; Available from: http:// www.nlm.nih.gov/medlineplus/ency/article/003488.htm.
    • (2010) Serum Iron. Serum Iron
  • 42
    • 0142089171 scopus 로고    scopus 로고
    • Prognostic value of myeloperoxidase in patients with chest pain
    • Brennan, M.L., et al., Prognostic value of myeloperoxidase in patients with chest pain. N Engl J Med, 2003. 349(17): pp. 1595-604.
    • (2003) N. Engl J. Med. , vol.349 , Issue.17 , pp. 1595-1604
    • Brennan, M.L.1
  • 43
    • 0141727730 scopus 로고    scopus 로고
    • Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
    • Baldus, S., et al., Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation, 2003. 108(12): Pp. 1440-5.
    • (2003) Circulation , vol.108 , Issue.12 , pp. 1440-1445
    • Baldus, S.1
  • 44
    • 18344382325 scopus 로고    scopus 로고
    • Biochemical and genetic markers of iron status and the risk of coronary artery disease: An angiographybased study
    • Bozzini, C., et al., Biochemical and genetic markers of iron status and the risk of coronary artery disease: An angiographybased study. Clin Chem, 2002. 48(4): Pp. 622-8.
    • (2002) Clin. Chem. , vol.48 , Issue.4 , pp. 622-628
    • Bozzini, C.1
  • 45
    • 0033606807 scopus 로고    scopus 로고
    • Iron atherosclerosis, and ischemic heart disease
    • De Valk, B. and J.J. Marx, Iron, atherosclerosis, and ischemic heart disease. Arch Intern Med, 1999. 159(14): Pp. 1542-8.
    • (1999) Arch. Intern. Med. , vol.159 , Issue.14 , pp. 1542-1548
    • De Valk, B.1    Marx, J.J.2
  • 46
    • 0033592397 scopus 로고    scopus 로고
    • Iron and the genetics of cardiovascular disease
    • Sullivan, J.L., Iron and the genetics of cardiovascular disease. Circulation, 1999. 100(12): Pp. 1260-3.
    • (1999) Circulation , vol.100 , Issue.12 , pp. 1260-1263
    • Sullivan, J.L.1
  • 47
    • 0033840089 scopus 로고    scopus 로고
    • Iron overload and atherosclerosis
    • Niederau, C., Iron overload and atherosclerosis. Hepatology, 2000. 32(3): Pp. 672-4.
    • (2000) Hepatology , vol.32 , Issue.3 , pp. 672-674
    • Niederau, C.1
  • 48
    • 79953060400 scopus 로고    scopus 로고
    • A framework for evaluating biomarkers for early Detection: Validation of biomarker panels for ovarian cancer
    • Zhu, C.S., et al., A framework for evaluating biomarkers for early Detection: validation of biomarker panels for ovarian cancer. Cancer Prev Res (Phila), 2011. 4(3): Pp. 375-83.
    • (2011) Cancer Prev. Res. (Phila , vol.4 , Issue.3 , pp. 375-383
    • Zhu, C.S.1
  • 49
    • 33644590867 scopus 로고    scopus 로고
    • Evaluating markers for the early Detection of cancer: Overview of study Designs andmethods
    • Baker, S.G., et al., Evaluating markers for the early Detection of cancer: Overview of study Designs andmethods. Clin Trials, 2006. 3(1): Pp. 43-56.
    • (2006) Clin. Trials. , vol.3 , Issue.1 , pp. 43-56
    • Baker, S.G.1
  • 50
    • 0028829508 scopus 로고
    • Toward an optimal algorithm for ovarian cancer screening with longitudinal tumor markers
    • Skates, S.J., et al., Toward an optimal algorithm for ovarian cancer screening with longitudinal tumor markers. Cancer, 1995. 76(10 Suppl): Pp. 2004-10.
    • (1995) Cancer , vol.76 , Issue.10 SUPPL. , pp. 2004-2010
    • Skates, S.J.1


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