Proteins with whey-acidic-protein motifs and cancer

Lancet Oncology

Volumn 7, Issue 2, 2006, Pages 167-174

  Bouchard, Dominique ^a   Morisset, Dany ^b   Bourbonnais, Yves ^c   Tremblay, Guy M ^a  

^a LAVAL UNIVERSITY   (Canada)

^b NATIONAL INSTITUTE OF BIOLOGY   (Slovenia)

^c UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; CA 125 ANTIGEN; CELL SURFACE RECEPTOR; COLONY STIMULATING FACTOR 1; CYCLINE; ELAFIN; GENISTEIN; GROWTH INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOCYTE ELASTASE; MOLECULAR MARKER; PROSTATE PROTEIN; PROTEIN LYSINE 6 OXIDASE; PROTEIN TYROSINE KINASE INHIBITOR; PROTEINASE INHIBITOR; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SOMATOMEDIN BINDING PROTEIN 3; TUMOR MARKER; UNCLASSIFIED DRUG; WHEY ACIDIC PROTEIN;

ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER INHIBITION; CANCER MORTALITY; CANCER RESEARCH; CARCINOGENESIS; EARLY DIAGNOSIS; EPIDIDYMIS; GENETIC CODE; GENETIC IDENTIFICATION; GENETIC SCREENING; GENETIC TRANSFECTION; HUMAN; LUNG NON SMALL CELL CANCER; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR BIOLOGY; MORBIDITY; NONHUMAN; OVARY CANCER; OVARY CARCINOMA; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; REVIEW; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM;

EPIDIDYMAL SECRETORY PROTEINS; HUMANS; MILK PROTEINS; NEOPLASMS; PROTEINASE INHIBITORY PROTEINS, SECRETORY; PROTEINS; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR; TUMOR MARKERS, BIOLOGICAL;

EID: 31544471830     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(06)70579-4     Document Type: Review

References (75)

1. Hennighausen LG Sippel AE Mouse whey acidic protein is a novel member of the family of 'four-disulphide core' proteins Nucleic Acids Res 10 1982 2677-2684
2. J Schalkwijk Wiedow S Hirose The trappin gene family: Proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core Biochem J 340 1999 569-577
3. PS Hiemstra Novel roles of protease inhibitors in infection and inflammation Biochem Soc Trans 30 2002 116-120
4. GM Tremblay E Vachon C Larouche Y Bourbonnais Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2) Chest 121 2002 582-588
5. DR Rowley TD Dang M Larsen et al. Purification of a novel protein (ps20) from urogenital sinus mesenchymal cells with growth inhibitory properties in vitro J Biol Chem 270 1995 22058-22065
6. SJ McAlhany SJ Ressler M Larsen et al. Promotion of angiogenesis by ps20 in the differential reactive stroma prostate cancer xenograft model Cancer Res 63 2003 5859-5865
7. HO Molhuizen J Schalkwijk Structural, biochemical, and cell biological aspects of the serine proteinase inhibitor SKALP/elafin/ESI Biol Chem Hoppe Seyler 376 1995 1-7
8. JH Dijkman Antileucoprotease in the airways and emphysema Monaldi Arch Chest Dis 50 1995 383-387
9. A Clauss H Lilja Lundwall Å A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein Biochem J 368 2002 233-242
10. L Bingle V Singleton CD Bingle The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms Oncogene 21 2002 68-2773
11. N Devoogdt H Revets GH Ghassabeh P De Baetselier Secretory leukocyte protease inhibitor in cancer development Ann N Y Acad Sci 1028 2004 380-389
12. B Jarzab M Wiench K Fujarewicz et al. Gene expression profile of papillary thyroid cancer: Sources of variability and diagnostic implications Cancer Res 65 2005 1587-1597
13. CA Iacobuzio-Donahue R Ashfaq A Maitra et al. Highly expressed genes in pancreatic ductal adenocarcinomas: A comprehensive characterization and comparison of the transcription profiles obtained from three major technologies Cancer Res 63 2003 8614-8622
14. B Ryu J Jones NJ Blades et al. Relationships and differentially expressed genes among pancreatic cancers examined by large-scale serial analysis of gene expression Cancer Res 62 2002 819-826
15. S Ameshima T Ishizaki Y Demura et al. Increased secretory leukoprotease inhibitor in patients with non-small-cell lung carcinoma Cancer 89 2000 448-1456
16. Y Hu H Sun J Drake et al. From mice to humans: Identification of commonly deregulated genes in mammary cancer via comparative SAGE studies Cancer Res 64 2004 7748-7755
17. F Bertucci P Finetti J Rougemont et al. Gene expression profiling for molecular characterization of inflammatory breast cancer and prediction of response to chemotherapy Cancer Res 64 2004 8558-8565
18. O Israeli A Goldring-Aviram S Rienstein et al. In silico chromosomal clustering of genes displaying altered expression patterns in ovarian cancer Cancer Genet Cytogenet 160 2005 35-42
19. CD Hough KR Cho AB Zonderman et al. Coordinately up-regulated genes in ovarian cancer Cancer Res 61 2001 3869-3876
20. DR Schwartz SL Kardia KA Shedden et al. Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas Cancer Res 62 2002 4722-4729
21. S Tsukishiro N Suzumori H Nishikawa et al. Use of serum secretory leukocyte protease inhibitor levels in patients to improve specificity of ovarian cancer diagnosis Gynecol Oncol 96 2005 516-519
22. DT Rein M Breidenbach DM Nettelbeck et al. Evaluation of tissue-specific promoters in carcinomas of the cervix uteri J Gene Med 6 2004 1281-1289
23. X Tian K Shigemasa E Hirata et al. Expression of human kallikrein 7 (hK7/ SCCE) and its inhibitor antileukoprotease (ALP/SLPI) in uterine endocervical glands and in cervical adenocarcinomas Oncol Rep 12 2004 1001-1006
24. V Sriuranpong A Mutirangura JW Gillespie et al. Global gene expression profile of nasopharyngeal carcinoma by laser capture microdissection and complementary DNA microarrays Clin Cancer Res 10 2004 4944-4958
25. D Zhang RC Simmen FJ Michel et al. Secretory leukocyte protease inhibitor mediates proliferation of human endometrial epithelial cells by positive and negative regulation of growth-associated genes J Biol Chem 277 2002 29 999-30 009
26. G Liang FA Gonzales PA Jones et al. Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine Cancer Res 62 2002 961-966
27. BA Smith WJ Kennedy P Harnden et al. Identification of genes involved in human urothelial cell-matrix interactions: Implications for the progression pathways of malignant urothelium Cancer Res 61 2001 1678-1685
28. HA Alkemade IM van Vlijmen-Willems UJ van Haelst et al. Demonstration of skin-derived antileukoproteinase (SKALP) and its target enzyme human leukocyte elastase in squamous cell carcinoma J Pathol 174 1994 121-129
29. S Yamamoto H Egami T Kurizaki et al. Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of the oesophagus Br J Cancer 76 1997 1081-1086
30. U Westin M Nystrom I Ljungcrantz et al. The presence of elafin, SLPI, IL1-RA and STNFαRI in head and neck squamous cell carcinomas and their relation to the degree of tumour differentiation Mediators Inflamm 11 2002 7-12
31. E Blaveri JP Simko JE Korkola et al. Bladder cancer outcome and subtype classification by gene expression Clin Cancer Res 11 2005 4044-4055
32. PA Robinson AF Markham J Schalkwijk AS High Increased elafin expression in cystic, dysplastic and neoplastic oral tissues J Oral Pathol Med 25 1996 135-139
33. N Yoshida H Egami J Yamashita et al. Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung Oncol Rep 9 2002 495-501
34. Y Li FH Sarkar Gene expression profiles of genistein-treated PC3 prostate cancer cells J Nutr 132 2002 3623-3631
35. TN Dechow L Pedranzini A Leitch et al. Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C Proc Natl Acad Sci USA 101 2004 10602-10607
36. I Hellstrom J Raycraft M Hayden-Ledbetter et al. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma Cancer Res 63 2003 3695-3700
37. V Shridhar J Lee A Pandita et al. Genetic analysis of early- versus late-stage ovarian tumors Cancer Res 61 2001 5895-5904
38. ME Schaner DT Ross G et al. Ciaravino Gene expression patterns in ovarian carcinomas Mol Biol Cell 14 2003 4376-4386
39. S Ashida H Nakagawa T Katagiri et al. Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: Genome-wide gene-expression profiles of prostate cancers and PINs Cancer Res 64 2004 5963-5972
40. R Saffroy P Riou G Soler et al. Analysis of alterations of WFDC1, a new putative tumour suppressor gene, in hepatocellular carcinoma Eur J Hum Genet 10 2002 239-244
41. JE Watson NA Doggett DG Albertson et al. Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23-qter and identifies underlying candidate tumor suppressor genes in prostate cancer Oncogene 23 2004 3487-3494
42. SJ McAlhany GE Ayala A Frolov et al. Decreased stromal expression and increased epithelial expression of WFDC1/ps20 in prostate cancer is associated with reduced recurrence-free survival Prostate 61 2004 182-191
43. HM Kluger Y Kluger M Gilmore-Hebert et al. cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model Lab Invest 84 2004 320-331
44. M Maemondo Y Saijo K Narumi et al. Gene therapy with secretory leukoprotease inhibitor promoter-controlled replication-competent adenovirus for non-small cell lung cancer Cancer Res 64 2004 4611-4620
45. Zelvyte A Wallmark E Piitulainen et al. Increased plasma levels of serine proteinase inhibitors in lung cancer patients Anticancer Res 24 2004 241-247
46. T Sugino T Kusakabe N Hoshi et al. An invasion-independent pathway of blood-borne metastasis: A new murine mammary tumor model Am J Pathol 160 2002 1973-1980
47. X Dolcet D Llobet J Pallares X Matias-Guiu NF-κB in development and progression of human cancer Virchows Arch 446 2005 475-482
48. P Viatour E Dejardin M Warnier et al. GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity Mol Cell 16 2004 35-45
49. DT Rein M Breidenbach TO Kirby et al. A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer Clin Cancer Res 11 2005 1327-1335
50. Z He A Bateman Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis J Mol Med 81 2003 600-612
51. S Li DT Ross ME Kadin et al. Comparative genome-scale analysis of gene expression profiles in T cell lymphoma cells during malignant progression using a complementary DNA microarray Am J Pathol 158 2001 1231-1237
52. CC Taggart CM Greene NG McElvaney S O'Neill Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IκBα degradation without affecting phosphorylation or ubiquitination J Biol Chem 277 2002 33648-33653
53. R Pfundt F van Ruissen IM van Vlijmen-Willems et al. Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia J Clin Invest 98 1996 1389-1399
54. GM Tremblay JM Sallenave E Israel-Assayag et al. Elafin/ elastase-specific inhibitor in bronchoalveolar lavage of normal subjects and farmer's lung Am J Respir Crit Care Med 154 1996 1092-1098
55. PC Fernandez SR Frank L Wang et al. Genomic targets of the human c-Myc protein Genes Dev 17 2003 1115-1129
56. M Colozza E Azambuja F Cardoso et al. Proliferative markers as prognostic and predictive tools in early breast cancer: Where are we now? Ann Oncol 16 2005 1723-1739
57. C Kirchhoff I Habben R Ivell N Krull A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors Biol Reprod 45 1991 350-357
58. R Drapkin HH von Horsten Y Lin et al. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas Cancer Res 65 2005 2162-2169
59. Anon Fujirebio diagnostics to develop new markers for the early detection of ovarian cancer Expert Rev Mol Diagn 2 2002 401-402
60. NB Berry YM Cho MA Harrington et al. Transcriptional targeting in ovarian cancer cells using the human epididymis protein 4 promoter Gynecol Oncol 92 2004 896-904
61. ME Garber OG Troyanskaya K Schluens et al. Diversity of gene expression in adenocarcinoma of the lung Proc Natl Acad Sci USA 98 2001 13784-13789
62. H Endoh S Tomida Y Yatabe et al. Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction J Clin Oncol 22 2004 811-819
63. M Larsen SJ Ressler MJ Gerdes et al. The WFDC1 gene encoding ps20 localizes to 16q24, a region of LOH in multiple cancers Mamm Genome 11 2000 767-773
64. J Sung J Turner S McCarthy et al. Oncogene regulation of tumor suppressor genes in tumorigenesis Carcinogenesis 26 2005 487-494
65. H Hung Suppression of ps20 expression in the rat uterus by tamoxifen and estrogens Endocrinology 146 2005 2388-2396
66. PA Henriksen M Hitt Z Xing et al. Adenoviral gene delivery of elafin and secretory leukocyte protease inhibitor attenuates NF-κB-dependent inflammatory responses of human endothelial cells and macrophages to atherogenic stimuli J Immunol 172 2004 4535-4544
67. J Yang J Zhu D Sun A Ding Suppression of macrophage responses to bacterial lipopolysaccharide (LPS) by secretory leukocyte protease inhibitor (SLPI) is independent of its anti-protease function Biochim Biophys Acta 1745 2005 310-317
68. TB McNeely DC Shugars M Rosendahl et al. Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription Blood 90 1997 1141-1149
69. N Devoogdt G Hassanzadeh Ghassabeh J Zhang et al. Secretory leukocyte protease inhibitor promotes the tumorigenic and metastatic potential of cancer cells Proc Natl Acad Sci USA 100 2003 5778-5782
70. J Schlingemann J Hess G Wrobel et al. Profile of gene expression induced by the tumour promotor TPA in murine epithelial cells Int J Cancer 104 2003 699-708
71. MM Rosenkilde TW Schwartz The chemokine system - a major regulator of angiogenesis in health and disease Apmis 112 2004 481-495
72. S Ballaz JL Mulshine The potential contributions of chronic inflammation to lung carcinogenesis Clin Lung Cancer 5 2003 46-62
73. L Bingle TD Tetley CD Bingle Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-κB Am J Respir Cell Mol Biol 25 2001 84-91
74. ML Zani SM Nobar SA Lacour et al. Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris Eur J Biochem 271 2004 2370-2378
75. C Boudier M Cadène JG Bieth Inhibition of neutrophil cathepsin G by oxidized mucus proteinase inhibitor. Effect of heparin Biochemistry 38 1999 8451-8457