Mechanism of hypochlorous acid-mediated heme destruction and free iron release

Free Radical Biology and Medicine

Volumn 51, Issue 2, 2011, Pages 364-373

  Maitra, Dhiman ^a   Byun, Jaeman ^c   Andreana, Peter R ^d   Abdulhamid, Ibrahim ^b   Saed, Ghassan M ^a   Diamond, Michael P ^a   Pennathur, Subramaniam ^c   Abu Soud, Husam M ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

Free iron; Free radicals; Heme deficiency; Heme degradation; Mammalian peroxidases; Mass spectrometry; Oxidative stress; Porphyrin; Stopped flow

Indexed keywords

DIMER; HEME; HYPOCHLOROUS ACID; IRON; MONOMER; PROTOPORPHYRIN; TETRAPYRROLE DERIVATIVE;

ABSORPTION; ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IRON KINETICS; LIQUID CHROMATOGRAPHY; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEME; HYPOCHLOROUS ACID; IRON; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MAMMALIA;

EID: 79959345072     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.03.040     Document Type: Article

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