Reaction of hemoglobin with HOCl: Mechanism of heme destruction and free iron release

Free Radical Biology and Medicine

Volumn 51, Issue 2, 2011, Pages 374-386

  Maitra, Dhiman ^a   Byun, Jaeman ^c   Andreana, Peter R ^d   Abdulhamid, Ibrahim ^b   Diamond, Michael P ^a   Saed, Ghassan M ^a   Pennathur, Subramaniam ^c   Abu Soud, Husam M ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

Free iron; Free radicals; Hemoglobin; Hypochlorous acid; Inflammation; Mammalian peroxidase; Oxidative stress; RBC

Indexed keywords

CARBON; HEME; HEMOGLOBIN; HYPOCHLOROUS ACID; IRON; PORPHYRIN; TETRAPYRROLE DERIVATIVE;

ARTICLE; ERYTHROCYTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IRON KINETICS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; STAINING;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEME; HEMOGLOBINS; HYPOCHLOROUS ACID; IRON; MASS SPECTROMETRY; SPECTROMETRY, FLUORESCENCE;

MAMMALIA;

EID: 79959340510     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.04.011     Document Type: Article

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