Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice

Neuropharmacology

Volumn 63, Issue 5, 2012, Pages 798-805

  Costa, Robson ^a   Motta, Emerson M ^a   Manjavachi, Marianne N ^a   Cola, Maíra ^a   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Alpha 7 nicotinic acetylcholine receptor; Colitis; Pain

Indexed keywords

4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; BUNGAROTOXIN RECEPTOR; NICOTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; COLITIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; HYPERALGESIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REFERRED PAIN;

ACONITINE; ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; BENZAMIDES; BICYCLO COMPOUNDS; COLITIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; HYPERALGESIA; MALE; MICE; MICE, INBRED STRAINS; MOLECULAR TARGETED THERAPY; NERVE TISSUE PROTEINS; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PAIN THRESHOLD; PAIN, REFERRED; RANDOM ALLOCATION; RECEPTORS, NICOTINIC;

EID: 84864441216     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.06.004     Document Type: Article

References (52)

1. M.J. Abdin, N. Morioka, and K. Morita Analgesic action of nicotine on tibial nerve transection (TNT)-induced mechanical allodynia through enhancement of the glycinergic inhibitory system in spinal cord Life Sci. 80 2006 9 16 (Pubitemid 44809291)
2. G.R. Abdrakhmanova, S. AlSharari, and M. Kang {alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis Am. J. Physiol. Gastrointest. Liver Physiol. 299 2010 G761 G768
3. M.D. Aceto, R.S. Bagley, and W.L. Dewey The spinal cord as a major site for the antinociceptive action of nicotine in the rat Neuropharmacology 25 1986 1031 1036 (Pubitemid 16050465)
4. F. Azpiroz, M. Bouin, and M. Camilleri Mechanisms of hypersensitivity in IBS and functional disorders Neurogastroenterol Motil. 19 2007 62 88 (Pubitemid 46058983)
5. A. Bai, Y. Guo, and N. Lu The effect of the cholinergic anti-inflammatory pathway on experimental colitis Scand. J. Immunol. 66 2007 538 545 (Pubitemid 47609702)
6. A.W. Bannon, M.W. Decker, and M.W. Holladay Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors Science 279 1998 77 81 (Pubitemid 28079158)
7. D.C. Baumgart, and S.R. Carding Inflammatory bowel disease: cause and immunobiology Lancet 369 2007 1627 1640 (Pubitemid 46722636)
8. A.F. Bento, D.F. Leite, and R.F. Claudino The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice J. Leukoc. Biol. 84 2008 1213 1221
9. K. Bielefeldt, K. Lamb, and G.F. Gebhart Convergence of sensory pathways in the development of somatic and visceral hypersensitivity Am. J. Physiol. Gastrointest. Liver Physiol. 291 2006 G658 G665
10. R.S. Bitner, A.L. Nikkel, and P. Curzon Role of the nucleus raphe magnus in antinociception produced by ABT-594: immediate early gene responses possibly linked to neuronal nicotinic acetylcholine receptors on serotonergic neurons J. Neurosci. 18 1998 5426 5432 (Pubitemid 28311958)
11. J.J. Bonica Evolution and current status of pain programs J. Pain Symptom Manage. 5 1990 368 374
12. L.V. Borovikova, S. Ivanova, and D. Nardi Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation Auton. Neurosci. 85 2000 141 147
13. R.F. Claudino, R. Marcon, and A.F. Bento Endothelins implicated in referred mechanical hyperalgesia associated with colitis induced by TNBS in mice Can. J. Physiol. Pharmacol. 88 2010 661 667
14. H.S. Cooper, S.N. Murthy, and R.S. Shah Clinicopathologic study of dextran sulfate sodium experimental murine colitis Lab. Invest. 69 1993 238 249
15. R. Costa, E.S. Fernandes, and O. Menezes-de-Lima Jr. Effect of novel selective non-peptide kinin B(1) receptor antagonists on mouse pleurisy induced by carrageenan Peptides 27 2006 2967 2975 (Pubitemid 44584423)
16. M.I. Damaj, M. Fei-Yin, and M. Dukat Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice J. Pharmacol. Exp. Ther. 284 1998 1058 1065 (Pubitemid 28130835)
17. M.I. Damaj, E.M. Meyer, and B.R. Martin The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model Neuropharmacology 39 2000 2785 2791
18. W.J. de Jonge, and L. Ulloa The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation Br. J. Pharmacol. 151 2007 915 929 (Pubitemid 47195518)
19. W.J. de Jonge, E.P. van der Zanden, and F.O. The Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway Nat. Immunol. 6 2005 844 851 (Pubitemid 43090471)
20. W.J. Dixon Efficient analysis of experimental observations Ann. Rev. Pharmacol. Toxicol. 20 1980 441 462
21. D. Feuerbach, K. Lingenhoehl, and H.R. Olpe The selective nicotinic acetylcholine receptor alpha7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain Neuropharmacology 56 2009 254 263
22. B. Gao, M. Hierl, and K. Clarkin Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain Pain 149 2010 33 49
23. J.R. Genzen, W. Van Cleve, and D.S. McGehee Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes J. Neurophysiol. 86 2001 1773 1782 (Pubitemid 32953226)
24. J.E. Ghia, P. Blennerhassett, and R.T. El-Sharkawy The protective effect of the vagus nerve in a murine model of chronic relapsing colitis Am. J. Physiol. Gastrointest. Liver Physiol. 293 2007 G711 G718
25. J.E. Ghia, P. Blennerhassett, and H. Kumar-Ondiveeran The vagus nerve: a tonic inhibitory influence associated with inflammatory bowel disease in a murine model Gastroenterology 131 2006 1122 1130 (Pubitemid 44498700)
26. R.V. Haberberger, N. Bernardini, and M. Kress Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat Auton. Neurosci. 113 2004 32 42 (Pubitemid 39024511)
27. E.S. Kimball, N.H. Wallace, and C.R. Schneider Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice Neurogastroenterol Motil. 16 2004 811 818 (Pubitemid 40022788)
28. C.H. Knowles, and Q. Aziz Basic and clinical aspects of gastrointestinal pain Pain 141 2009 191 209
29. J.M. Laird, V. Souslova, and J.N. Wood Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice J. Neurosci. 22 2002 8352 8356 (Pubitemid 35387574)
30. K. Lamb, F. Zhong, and G.F. Gebhart Experimental colitis in mice and sensitization of converging visceral and somatic afferent pathways Am. J. Physiol. Gastrointest. Liver Physiol. 290 2006 G451 G457
31. L. Liu, W. Zhu, and Z.S. Zhang Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors J. Neurophysiol. 91 2004 1482 1491 (Pubitemid 38339320)
32. L.C. Loram, J.A. Harrison, and L. Chao Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats Brain Behav. Immun. 24 2010 959 967
33. L.M. Marubio, M. del Mar Arroyo-Jimenez, and M. Cordero-Erausquin Reduced antinociception in mice lacking neuronal nicotinic receptor subunits Nature 398 1999 805 810
34. J. McGrath, J.W. McDonald, and J.K. Macdonald Transdermal nicotine for induction of remission in ulcerative colitis Cochrane Database Syst. Rev. 2004 CD004722
35. S.J. Medhurst, J.P. Hatcher, and C.J. Hille Activation of the alpha7-nicotinic acetylcholine receptor reverses complete freund adjuvant-induced mechanical hyperalgesia in the rat via a central site of action J. Pain 9 2008 580 587
36. A. Pacini, L. Di Cesare Mannelli, and L. Bonaccini Protective effect of alpha7 nAChR: behavioural and morphological features on neuropathy Pain 150 2010 542 549
37. D.V. Phan, M. Doda, and A. Bite Antin ociceptive activity of nicotine Acta Physiol. Acad. Sci. Hung 44 1973 85 93
38. R.D. Pullan, J. Rhodes, and S. Ganesh Transdermal nicotine for active ulcerative colitis N. Engl. J. Med. 330 1994 811 815 (Pubitemid 24083559)
39. T.S. Rao, L.D. Correa, and R.T. Reid Evaluation of anti-nociceptive effects of neuronal nicotinic acetylcholine receptor (NAChR) ligands in the rat tail-flick assay Neuropharmacology 35 1996 393 405 (Pubitemid 26189383)
40. S.A. Snoek, M.I. Verstege, and E.P. van der Zanden Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis Br. J. Pharmacol. 160 2010 322 333
41. W. Strober, I. Fuss, and P. Mannon The fundamental basis of inflammatory bowel disease J. Clin. Invest. 117 2007 514 521 (Pubitemid 46348505)
42. X. Su, J.W. Lee, and Z.A. Matthay Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats Am. J. Respir. Cell Mol. Biol. 37 2007 186 192 (Pubitemid 47255001)
43. M.V. Tobin, R.F. Logan, and M.J. Langman Cigarette smoking and inflammatory bowel disease Gastroenterology 93 1987 316 321 (Pubitemid 17097599)
44. K.J. Tracey The inflammatory reflex Nature 420 2002 853 859 (Pubitemid 36019638)
45. L. Ulloa The vagus nerve and the nicotinic anti-inflammatory pathway Nat. Rev. Drug Discov. 4 2005 673 684 (Pubitemid 41149761)
46. M. Van der Sluis, B.A. De Koning, and A.C. De Bruijn Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection Gastroenterology 131 2006 117 129 (Pubitemid 44015753)
47. D.J. van Westerloo, I.A. Giebelen, and S. Florquin The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis J. Infect. Dis. 191 2005 2138 2148 (Pubitemid 40800586)
48. L.P. Vera-Portocarrero, J.Y. Xie, and J. Kowal Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis Gastroenterology 130 2006 2155 2164 (Pubitemid 43816956)
49. H. Wang, H. Liao, and M. Ochani Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis Nat. Med. 10 2004 1216 1221 (Pubitemid 39540438)
50. H. Wang, M. Yu, and M. Ochani Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation Nature 421 2003 384 388 (Pubitemid 36157937)
51. Y. Wang, D.M. Su, and R.H. Wang Antinociceptive effects of choline against acute and inflammatory pain Neuroscience 132 2005 49 56 (Pubitemid 40380713)
52. Q. Zhou, D.D. Price, and R.M. Caudle Visceral and somatic hypersensitivity in TNBS-induced colitis in rats Dig. Dis. Sci. 53 2008 429 435 (Pubitemid 351170021)