Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy

Laboratory Investigation

Volumn 92, Issue 8, 2012, Pages 1149-1160

  Du, Xuanyi ^a,b   Shimizu, Akira ^a   Masuda, Yukinari ^a   Kuwahara, Naomi ^a   Arai, Takashi ^a   Kataoka, Mitue ^a   Uchiyama, Masaaki ^a   Kaneko, Tomohiro ^a   Akimoto, Toshio ^a   Iino, Yasuhiko ^a   Fukuda, Yuh ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

epithelial to mesenchymal transition; MMP inhibitor; MMP 2; renal fibrosis; tubular epithelial cell

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; CALVASCULIN; COLLAGEN TYPE 1; GELATINASE A; GELATINASE B; HEAT SHOCK PROTEIN 47; INTEGRIN LINKED KINASE; MINOCYCLINE; SMAD PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EPITHELIAL MESENCHYMAL TRANSITION; HISTOPATHOLOGY; KIDNEY DISEASE; KIDNEY FIBROSIS; MALE; MESENCHYME CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; URETER OBSTRUCTION;

ANIMALS; COLLAGEN; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; GENE EXPRESSION REGULATION; HISTOCYTOCHEMISTRY; KIDNEY DISEASES; KIDNEY TUBULES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, TRANSGENIC; MINOCYCLINE; PHENOTYPE; RNA, MESSENGER; S100 PROTEINS; URETERAL OBSTRUCTION;

EID: 84864434406     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2012.68     Document Type: Article

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