Discovery and structure-activity analysis of selective estrogen receptor modulators via similarity-based virtual screening

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 188-196

  Shen, Jie ^a   Jiang, Jing ^a   Kuang, Guanglin ^a   Tan, Chengfang ^a   Liu, Guixia ^a   Huang, Jin ^a   Tang, Yun ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Anti proliferative; ER; SERM; Similarity search; Virtual screening

Indexed keywords

CYCLIN D1; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION;

CELL PROLIFERATION; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MCF-7 CELLS; MOLECULAR DOCKING SIMULATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ESTROGEN; SELECTIVE ESTROGEN RECEPTOR MODULATORS; STRUCTURE-ACTIVITY RELATIONSHIP; USER-COMPUTER INTERFACE;

EID: 84864416292     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.04.041     Document Type: Article

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