Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Beck, Raphaël ^a   Dejeans, Nicolas ^a   Glorieux, Christophe ^a   Creton, Mélanie ^a   Delaive, Edouard ^b   Dieu, Marc ^b   Raes, Martine ^b   Levêque, Philippe ^a   Gallez, Bernard ^a   Depuydt, Matthieu ^c   Collet, Jean François ^c   Calderon, Pedro Buc ^a,d   Verrax, Julien ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b University of Namur   (Belgium)

^c DE DUVE INSTITUTE   (Belgium)

^d UNIVERSIDAD ARTURO PRAT   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BCR ABL PROTEIN; GLYCINE; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90BETA; I KAPPA B KINASE GAMMA; IRON; NUCLEOTIDE; PROTEIN; PROTEIN C RAF; PROTEIN RIP; RAF PROTEIN; REACTIVE OXYGEN METABOLITE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL STRESS; CONTROLLED STUDY; FENTON REACTION; GENETIC CONSERVATION; HOMEOSTASIS; HUMAN; HUMAN CELL; NUCLEOTIDE BINDING SITE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN DEFECT; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEOMICS;

AMINO ACID MOTIFS; HOMEOSTASIS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IRON; K562 CELLS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEOLYSIS; REACTIVE OXYGEN SPECIES;

EID: 84864414686     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040795     Document Type: Article

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