Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine

Phytomedicine

Volumn 19, Issue 10, 2012, Pages 930-939

  Ulrich Merzenich, G ^a   Kelber, O ^b   Koptina, A ^a,e   Freischmidt, A ^c   Heilmann, J ^c   Muller J ^b   Zeitler, H ^a   Seidel, M F ^a   Ludwig, M ^a   Heinrich, E U ^b   Winterhoff, H ^d  

^a UNIVERSITY OF BONN   (Germany)

^b Steigerwald Arzneimittelwerk GmbH   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d UNIVERSITY OF MÜNSTER   (Germany)

^e VOLGA STATE UNIVERSITY OF TECHNOLOGY   (Russian Federation)

Author keywords

Inflammation; Microarray; Multitargeting; Neurological diseases; Polyphenols; Salicylates

Indexed keywords

ANTIDEPRESSANT AGENT; CHALCONE DERIVATIVE; CYP26B PROTEIN; DNM1L PROTEIN; FLAVONE; FLAVONOID GLYCOSIDE; GLYCOSIDE; GRIA 2 PROTEIN; IMIPRAMINE; INTERLEUKIN 10; INTERLEUKIN 3; KITLG PROTEIN; PLANT EXTRACT; POLYPHENOL; PROTEIN; SALIGENIN; SRP54 PROTEIN; UNCLASSIFIED DRUG; WILLOW EXTRACT;

ANTIDEPRESSANT ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; DRUG EFFECT; FORCED SWIMMING TEST; GENE CONTROL; GENE EXPRESSION; HIPPOCAMPUS; MALE; MEDICINAL PLANT; MICROARRAY ANALYSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; WILLOW;

ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BENZYL ALCOHOLS; BRAIN; CYTOKINES; DEPRESSION; DRUG DELIVERY SYSTEMS; FLAVONOIDS; GENE EXPRESSION; GLUCOSIDES; IMIPRAMINE; INFLAMMATION; MALE; MICROARRAY ANALYSIS; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SALICYLIC ACID; SALIX; SEROTONIN; SWIMMING;

RATTUS; SALIX;

EID: 84864413904     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.05.004     Document Type: Article

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