메뉴 건너뛰기




Volumn 213, Issue 2, 2012, Pages 203-210

Luminal transport of thiol S-conjugates of methylmercury in isolated perfused rabbit renal proximal tubules

Author keywords

Amino acid transporters; Membrane transport; Methylmercury; Molecular mimicry; Renal proximal tubular segments; Thiol S conjugates

Indexed keywords

2,3 BIS(SULFANYL)PROPANE 1 SULFONATE; ACETYLCYSTEINE; ACIVICIN; AMINO ACID TRANSPORTER; CYSTEINE; GLUTATHIONE; METHIONINE; METHYLMERCURY; UNCLASSIFIED DRUG;

EID: 84864404564     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.07.003     Document Type: Article
Times cited : (7)

References (37)
  • 1
    • 0020644951 scopus 로고
    • DMSA and DMPS-water soluble antidotes for heavy metal poisoning
    • Aposhian H.V. DMSA and DMPS-water soluble antidotes for heavy metal poisoning. Annual Review of Pharmacology and Toxicology 1983, 23:193-215.
    • (1983) Annual Review of Pharmacology and Toxicology , vol.23 , pp. 193-215
    • Aposhian, H.V.1
  • 3
    • 40949106884 scopus 로고    scopus 로고
    • N-Acetylcysteine as a potential antidote and biomonitoring agent of methylmercury exposure
    • Aremu D.A., Madejczyk M.S., et al. N-Acetylcysteine as a potential antidote and biomonitoring agent of methylmercury exposure. Environmental Health Perspectives 2008, 116(1):26-31.
    • (2008) Environmental Health Perspectives , vol.116 , Issue.1 , pp. 26-31
    • Aremu, D.A.1    Madejczyk, M.S.2
  • 4
    • 0023748960 scopus 로고
    • Uptake of methylmercury in the rat brain: effects of amino acids
    • Aschner M., Clarkson T.W. Uptake of methylmercury in the rat brain: effects of amino acids. Brain Research 1988, 462(1):31-39.
    • (1988) Brain Research , vol.462 , Issue.1 , pp. 31-39
    • Aschner, M.1    Clarkson, T.W.2
  • 5
    • 0036802623 scopus 로고    scopus 로고
    • Transport of toxic metals by molecular mimicry
    • Ballatori N. Transport of toxic metals by molecular mimicry. Environmental Health Perspectives 2002, 110(Suppl. 5):689-694.
    • (2002) Environmental Health Perspectives , vol.110 , Issue.SUPPL. 5 , pp. 689-694
    • Ballatori, N.1
  • 6
  • 8
    • 1542349048 scopus 로고    scopus 로고
    • Mercuric conjugates of cysteine are transported by the amino acid transporter system b(0,+): implications of molecular mimicry
    • Bridges C.C., Bauch C., et al. Mercuric conjugates of cysteine are transported by the amino acid transporter system b(0,+): implications of molecular mimicry. Journal of the American Society of Nephrology 2004, 15(3):663-673.
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.3 , pp. 663-673
    • Bridges, C.C.1    Bauch, C.2
  • 10
    • 38349170961 scopus 로고    scopus 로고
    • Amino acid transport across mammalian intestinal and renal epithelia
    • Broer S. Amino acid transport across mammalian intestinal and renal epithelia. Physiological Reviews 2008, 88(1):249-286.
    • (2008) Physiological Reviews , vol.88 , Issue.1 , pp. 249-286
    • Broer, S.1
  • 11
    • 0000228139 scopus 로고
    • The chemistry of mercury in biological systems
    • Elsevier/North Holand Biomedical Press, Amsterdam
    • Carty A.J., Malone S.J. The chemistry of mercury in biological systems. The Biogeochemistry of Mercury in the Environment 1979, vol. 3:433-479. Elsevier/North Holand Biomedical Press, Amsterdam.
    • (1979) The Biogeochemistry of Mercury in the Environment , vol.3 , pp. 433-479
    • Carty, A.J.1    Malone, S.J.2
  • 12
    • 0036177730 scopus 로고    scopus 로고
    • The three modern faces of mercury
    • Clarkson T.W. The three modern faces of mercury. Environmental Health Perspectives 2002, 110(Suppl. 1):11-23.
    • (2002) Environmental Health Perspectives , vol.110 , Issue.SUPPL. 1 , pp. 11-23
    • Clarkson, T.W.1
  • 13
    • 0025095554 scopus 로고
    • Role of gamma-glutamyltranspeptidase and beta-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice
    • de Ceaurriz J., Ban M. Role of gamma-glutamyltranspeptidase and beta-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice. Toxicology Letters 1990, 50(2-3):249-256.
    • (1990) Toxicology Letters , vol.50 , Issue.2-3 , pp. 249-256
    • de Ceaurriz, J.1    Ban, M.2
  • 14
    • 0028283126 scopus 로고
    • Transport of the glutathione-methylmercury complex across liver canalicular membranes on reduced glutathione carriers
    • Dutczak W.J., Ballatori N. Transport of the glutathione-methylmercury complex across liver canalicular membranes on reduced glutathione carriers. Journal of Biological Chemistry 1994, 269(13):9746-9751.
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.13 , pp. 9746-9751
    • Dutczak, W.J.1    Ballatori, N.2
  • 15
    • 0038539447 scopus 로고    scopus 로고
    • Regulation of renal amino acid (AA) transport by hormones, drugs and xenobiotics - a review
    • Fleck C., Schwertfeger M., et al. Regulation of renal amino acid (AA) transport by hormones, drugs and xenobiotics - a review. Amino Acids 2003, 24(4):347-374.
    • (2003) Amino Acids , vol.24 , Issue.4 , pp. 347-374
    • Fleck, C.1    Schwertfeger, M.2
  • 16
    • 0015928581 scopus 로고
    • Nuclear magnetic resonance studies of the solution chemistry of metal complexes. IX. The binding of cadmium, zinc, lead, and mercury by glutathione
    • Fuhr B.J., Rabenstein D.L. Nuclear magnetic resonance studies of the solution chemistry of metal complexes. IX. The binding of cadmium, zinc, lead, and mercury by glutathione. Journal of the American Chemical Society 1973, 95(21):6944-6950.
    • (1973) Journal of the American Chemical Society , vol.95 , Issue.21 , pp. 6944-6950
    • Fuhr, B.J.1    Rabenstein, D.L.2
  • 17
    • 0027754167 scopus 로고
    • RBAT, related to L-cysteine transport, is localized to the microvilli of proximal straight tubules, and its expression is regulated in kidney by development
    • Furriols M., Chillaron J., et al. rBAT, related to L-cysteine transport, is localized to the microvilli of proximal straight tubules, and its expression is regulated in kidney by development. Journal of Biological Chemistry 1993, 268(36):27060-27068.
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.36 , pp. 27060-27068
    • Furriols, M.1    Chillaron, J.2
  • 18
    • 0023179359 scopus 로고
    • Effect of inhibition of gamma-glutamyltranspeptidase on biliary and urinary excretion of glutathione-derived thiols and methylmercury
    • Gregus Z., Stein A.F., et al. Effect of inhibition of gamma-glutamyltranspeptidase on biliary and urinary excretion of glutathione-derived thiols and methylmercury. Journal of Pharmacology and Experimental Therapeutics 1987, 242(1):27-32.
    • (1987) Journal of Pharmacology and Experimental Therapeutics , vol.242 , Issue.1 , pp. 27-32
    • Gregus, Z.1    Stein, A.F.2
  • 19
    • 0018866764 scopus 로고
    • The relationship between blood levels and dose of methylmercury in man
    • Kershaw T.G., Clarkson T.W., et al. The relationship between blood levels and dose of methylmercury in man. Archives of Environment Health 1980, 35(1):28-36.
    • (1980) Archives of Environment Health , vol.35 , Issue.1 , pp. 28-36
    • Kershaw, T.G.1    Clarkson, T.W.2
  • 20
    • 0036784093 scopus 로고    scopus 로고
    • Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1
    • Koh A.S., Simmons-Willis T.A., et al. Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1. Molecular Pharmacology 2002, 62(4):921-926.
    • (2002) Molecular Pharmacology , vol.62 , Issue.4 , pp. 921-926
    • Koh, A.S.1    Simmons-Willis, T.A.2
  • 21
    • 34250693618 scopus 로고    scopus 로고
    • Accelerated urinary excretion of methylmercury following administration of its antidote N-acetylcysteine requires Mrp2/Abcc2, the apical multidrug resistance-associated protein
    • Madejczyk M.S., Aremu D.A., et al. Accelerated urinary excretion of methylmercury following administration of its antidote N-acetylcysteine requires Mrp2/Abcc2, the apical multidrug resistance-associated protein. Journal of Pharmacology and Experimental Therapeutics 2007, 322(1):378-384.
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.322 , Issue.1 , pp. 378-384
    • Madejczyk, M.S.1    Aremu, D.A.2
  • 22
    • 0028904550 scopus 로고
    • Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L
    • Mokrzan E.M., Kerper L.E., et al. Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L. Journal of Pharmacology and Experimental Therapeutics 1995, 272(3):1277-1284.
    • (1995) Journal of Pharmacology and Experimental Therapeutics , vol.272 , Issue.3 , pp. 1277-1284
    • Mokrzan, E.M.1    Kerper, L.E.2
  • 23
    • 0029877158 scopus 로고    scopus 로고
    • The rBAT gene is responsible for l-cystine uptake via the b0(+)-like amino acid transport system in a "renal proximal tubular" cell line (OK cells)
    • Mora C., Chillaron J., et al. The rBAT gene is responsible for l-cystine uptake via the b0(+)-like amino acid transport system in a "renal proximal tubular" cell line (OK cells). Journal of Biological Chemistry 1996, 271(18):10569-10576.
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.18 , pp. 10569-10576
    • Mora, C.1    Chillaron, J.2
  • 24
    • 0024286512 scopus 로고
    • Possible role of hepatic glutathione in transport of methylmercury into mouse kidney
    • Naganuma A., Oda-Urano N., et al. Possible role of hepatic glutathione in transport of methylmercury into mouse kidney. Biochemical Pharmacology 1988, 37(2):291-296.
    • (1988) Biochemical Pharmacology , vol.37 , Issue.2 , pp. 291-296
    • Naganuma, A.1    Oda-Urano, N.2
  • 25
    • 0035870096 scopus 로고    scopus 로고
    • --coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes
    • --coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes. The Journal of Physiology 2001, 532(Pt 2):297-304.
    • (2001) The Journal of Physiology , vol.532 , Issue.PT 2 , pp. 297-304
    • Nakanishi, T.1    Hatanaka, T.2
  • 28
    • 0036798145 scopus 로고    scopus 로고
    • Transport of a neurotoxicant by molecular mimicry: the methylmercury-l-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2
    • Simmons-Willis T.A., Koh A.S., et al. Transport of a neurotoxicant by molecular mimicry: the methylmercury-l-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2. Biochemical Journal 2002, 367(Pt 1):239-246.
    • (2002) Biochemical Journal , vol.367 , Issue.PT 1 , pp. 239-246
    • Simmons-Willis, T.A.1    Koh, A.S.2
  • 29
    • 0033588179 scopus 로고    scopus 로고
    • Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+)
    • Sloan J.L., Mager S. Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+). Journal of Biological Chemistry 1999, 274(34):23740-23745.
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.34 , pp. 23740-23745
    • Sloan, J.L.1    Mager, S.2
  • 30
    • 75749103651 scopus 로고    scopus 로고
    • Potential mechanisms involved in the absorptive transport of cadmium in isolated perfused rabbit renal proximal tubules
    • Wang Y., Zalups R.K., et al. Potential mechanisms involved in the absorptive transport of cadmium in isolated perfused rabbit renal proximal tubules. Toxicology Letters 2010, 193(1):61-68.
    • (2010) Toxicology Letters , vol.193 , Issue.1 , pp. 61-68
    • Wang, Y.1    Zalups, R.K.2
  • 31
    • 84984577326 scopus 로고    scopus 로고
    • The methylmercury-l-cysteine conjugate is a substrate for the l-type large neutral amino acid transporter
    • Yin Z., Jiang H., et al. The methylmercury-l-cysteine conjugate is a substrate for the l-type large neutral amino acid transporter. Journal of Neurochemistry 2008, 107(4):1083-1090.
    • (2008) Journal of Neurochemistry , vol.107 , Issue.4 , pp. 1083-1090
    • Yin, Z.1    Jiang, H.2
  • 32
    • 0034006391 scopus 로고    scopus 로고
    • Molecular interactions with mercury in the kidney
    • Zalups R.K. Molecular interactions with mercury in the kidney. Pharmacological Reviews 2000, 52(1):113-143.
    • (2000) Pharmacological Reviews , vol.52 , Issue.1 , pp. 113-143
    • Zalups, R.K.1
  • 33
    • 27144493053 scopus 로고    scopus 로고
    • Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1
    • Zalups R.K., Ahmad S. Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1. Kidney International 2005, 68(4):1684-1699.
    • (2005) Kidney International , vol.68 , Issue.4 , pp. 1684-1699
    • Zalups, R.K.1    Ahmad, S.2
  • 34
    • 27144503121 scopus 로고    scopus 로고
    • Handling of the homocysteine S-conjugate of methylmercury by renal epithelial cells: role of organic anion transporter 1 and amino acid transporters
    • Zalups R.K., Ahmad S. Handling of the homocysteine S-conjugate of methylmercury by renal epithelial cells: role of organic anion transporter 1 and amino acid transporters. Journal of Pharmacology and Experimental Therapeutics 2005, 315(2):896-904.
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.315 , Issue.2 , pp. 896-904
    • Zalups, R.K.1    Ahmad, S.2
  • 35
    • 23944510034 scopus 로고    scopus 로고
    • Transport of N-acetylcysteine s-conjugates of methylmercury in Madin-Darby canine kidney cells stably transfected with human isoform of organic anion transporter 1
    • Zalups R.K., Ahmad S. Transport of N-acetylcysteine s-conjugates of methylmercury in Madin-Darby canine kidney cells stably transfected with human isoform of organic anion transporter 1. Journal of Pharmacology and Experimental Therapeutics 2005, 314(3):1158-1168.
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.314 , Issue.3 , pp. 1158-1168
    • Zalups, R.K.1    Ahmad, S.2
  • 36
    • 0027305124 scopus 로고
    • Transport and toxicity of methylmercury along the proximal tubule of the rabbit
    • Zalups R.K., Barfuss D.W. Transport and toxicity of methylmercury along the proximal tubule of the rabbit. Toxicology and Applied Pharmacology 1993, 121(2):176-185.
    • (1993) Toxicology and Applied Pharmacology , vol.121 , Issue.2 , pp. 176-185
    • Zalups, R.K.1    Barfuss, D.W.2
  • 37
    • 59149096017 scopus 로고    scopus 로고
    • MRP2 involvement in renal proximal tubular elimination of methylmercury mediated by DMPS or DMSA
    • Zalups R.K., Bridges C.C. MRP2 involvement in renal proximal tubular elimination of methylmercury mediated by DMPS or DMSA. Toxicology and Applied Pharmacology 2009, 235(1):10-17.
    • (2009) Toxicology and Applied Pharmacology , vol.235 , Issue.1 , pp. 10-17
    • Zalups, R.K.1    Bridges, C.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.