A novel cyclin-dependent kinase inhibitor down-regulates tumor necrosis factor-α (TNF-α)-induced expression of cell adhesion molecules by inhibition of NF-κB activation in human pulmonary epithelial cells

International Immunopharmacology

Volumn 10, Issue 5, 2010, Pages 572-579

  Oh, Jung Hwa ^a   Park, Eun Jung ^a   Park, Jong Wook ^a   Lee, Jinho ^a   Lee, Sang Han ^b   Kwon, Taeg Kyu ^a  

^a Keimyung University   (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

A549 cells; BAI; Inflammatory disease; Intercellular adhesion molecule 1; Nuclear factor B; Vascular cell adhesion molecule 1

Indexed keywords

2 [1,1' BIPHENYL] 4 YL N [5 (1,1 DIOXO 1GAMMA6 ISOTHIAZOLIDIN 2 YL) 1H INDAZOL 3 YL] ACETAMIDE; ANTIINFLAMMATORY AGENT; CYCLIN DEPENDENT KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

AIRWAY INFLAMMATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; DRUG MECHANISM; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ADHERENCE; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESPIRATORY TRACT DISEASE; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL ADHESION; CELL LINE; CELL NUCLEUS; CYCLIN-DEPENDENT KINASES; DOWN-REGULATION; HUMANS; INDAZOLES; INTERCELLULAR ADHESION MOLECULE-1; NF-KAPPA B; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA; THIAZOLIDINES; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 77950516532     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.02.004     Document Type: Article

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