메뉴 건너뛰기




Volumn 20, Issue 7, 2009, Pages 341-348

FGFs in endochondral skeletal development

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 14; FIBROBLAST GROWTH FACTOR 16; FIBROBLAST GROWTH FACTOR 18; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 5; FIBROBLAST GROWTH FACTOR 6; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 4; KERATINOCYTE GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE B; PROTEIN KINASE C; SONIC HEDGEHOG PROTEIN; STAT PROTEIN; TRANSCRIPTION FACTOR SOX9; WNT PROTEIN;

EID: 69849107415     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2009.04.003     Document Type: Review
Times cited : (45)

References (59)
  • 1
    • 2642595047 scopus 로고    scopus 로고
    • The roles of FGFs in the early development of vertebrate limbs
    • Martin G.R. The roles of FGFs in the early development of vertebrate limbs. Genes Dev. 12 (1998) 1571-1586
    • (1998) Genes Dev. , vol.12 , pp. 1571-1586
    • Martin, G.R.1
  • 2
    • 0037097976 scopus 로고    scopus 로고
    • FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
    • Ornitz D.M., and Marie P.J. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev. 16 (2002) 1446-1465
    • (2002) Genes Dev. , vol.16 , pp. 1446-1465
    • Ornitz, D.M.1    Marie, P.J.2
  • 3
    • 18144383021 scopus 로고    scopus 로고
    • Cellular signaling by fibroblast growth factor receptors
    • Eswarakumar V.P., et al. Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev. 16 (2005) 139-149
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 139-149
    • Eswarakumar, V.P.1
  • 4
    • 18144391965 scopus 로고    scopus 로고
    • FGF signaling in the developing endochondral skeleton
    • Ornitz D.M. FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev. 16 (2005) 205-213
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 205-213
    • Ornitz, D.M.1
  • 5
    • 17244379023 scopus 로고    scopus 로고
    • Roles of FGF signaling in skeletal development and human genetic diseases
    • Chen L., and Deng C.X. Roles of FGF signaling in skeletal development and human genetic diseases. Front. Biosci. 10 (2005) 1961-1976
    • (2005) Front. Biosci. , vol.10 , pp. 1961-1976
    • Chen, L.1    Deng, C.X.2
  • 6
    • 38449096256 scopus 로고    scopus 로고
    • FGF signaling: its role in bone development and human skeleton diseases
    • Su N., et al. FGF signaling: its role in bone development and human skeleton diseases. Front. Biosci. 13 (2008) 2842-2865
    • (2008) Front. Biosci. , vol.13 , pp. 2842-2865
    • Su, N.1
  • 7
    • 43749110077 scopus 로고    scopus 로고
    • Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning
    • Mariani F.V., et al. Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning. Nature 453 (2008) 401-405
    • (2008) Nature , vol.453 , pp. 401-405
    • Mariani, F.V.1
  • 8
    • 38149134409 scopus 로고    scopus 로고
    • Functional evolutionary history of the mouse Fgf gene family
    • Itoh N., and Ornitz D.M. Functional evolutionary history of the mouse Fgf gene family. Dev. Dyn. 237 (2008) 18-27
    • (2008) Dev. Dyn. , vol.237 , pp. 18-27
    • Itoh, N.1    Ornitz, D.M.2
  • 9
    • 18144423534 scopus 로고    scopus 로고
    • Structural basis for fibroblast growth factor receptor activation
    • Mohammadi M., et al. Structural basis for fibroblast growth factor receptor activation. Cytokine Growth Factor Rev. 16 (2005) 107-137
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 107-137
    • Mohammadi, M.1
  • 10
    • 34548250374 scopus 로고    scopus 로고
    • A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases
    • Chen H., et al. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol. Cell 27 (2007) 717-730
    • (2007) Mol. Cell , vol.27 , pp. 717-730
    • Chen, H.1
  • 11
    • 18144415072 scopus 로고    scopus 로고
    • Mechanisms underlying differential responses to FGF signaling
    • Dailey L., et al. Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Rev. 16 (2005) 233-247
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 233-247
    • Dailey, L.1
  • 12
    • 0035168141 scopus 로고    scopus 로고
    • Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation
    • Hart K.C., et al. Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Mol. Biol. Cell 12 (2001) 931-942
    • (2001) Mol. Biol. Cell , vol.12 , pp. 931-942
    • Hart, K.C.1
  • 13
    • 33846067098 scopus 로고    scopus 로고
    • BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways
    • Yoon B.S., et al. BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development 133 (2006) 4667-4678
    • (2006) Development , vol.133 , pp. 4667-4678
    • Yoon, B.S.1
  • 14
    • 15944388991 scopus 로고    scopus 로고
    • Co-ordination of TGF-beta and FGF signaling pathways in bone organ cultures
    • Mukherjee A., et al. Co-ordination of TGF-beta and FGF signaling pathways in bone organ cultures. Mech. Dev. 122 (2005) 557-571
    • (2005) Mech. Dev. , vol.122 , pp. 557-571
    • Mukherjee, A.1
  • 15
    • 0345743700 scopus 로고    scopus 로고
    • Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia
    • Cho J.Y., et al. Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 609-614
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 609-614
    • Cho, J.Y.1
  • 16
    • 54249152045 scopus 로고    scopus 로고
    • Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
    • Haugsten E.M., et al. Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Mol. Biol. Cell 19 (2008) 3390-3403
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3390-3403
    • Haugsten, E.M.1
  • 17
    • 40549108924 scopus 로고    scopus 로고
    • Controlling receptor downregulation by ubiquitination and deubiquitination
    • Komada M. Controlling receptor downregulation by ubiquitination and deubiquitination. Curr. Drug Discov. Technol. 5 (2008) 78-84
    • (2008) Curr. Drug Discov. Technol. , vol.5 , pp. 78-84
    • Komada, M.1
  • 18
    • 84889782793 scopus 로고    scopus 로고
    • Skeletal development
    • Unsicker K., and Krieglstein K. (Eds), Wiley-VCH Verlag GmbH & Co
    • Horton W.A. Skeletal development. In: Unsicker K., and Krieglstein K. (Eds). Cell Signaling and Growth Factors in Development (2006), Wiley-VCH Verlag GmbH & Co 619-640
    • (2006) Cell Signaling and Growth Factors in Development , pp. 619-640
    • Horton, W.A.1
  • 19
    • 58149388206 scopus 로고    scopus 로고
    • Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development
    • ten Berge D., et al. Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development. Development 135 (2008) 3247-3257
    • (2008) Development , vol.135 , pp. 3247-3257
    • ten Berge, D.1
  • 20
    • 59849090189 scopus 로고    scopus 로고
    • Growth and patterning in the limb: signaling gradients make the decision
    • Yang Y. Growth and patterning in the limb: signaling gradients make the decision. Sci. Signal 2 (2009) pe3
    • (2009) Sci. Signal , vol.2
    • Yang, Y.1
  • 21
    • 7744225334 scopus 로고    scopus 로고
    • Morphology and chemical composition of connective tissue: cartilage
    • Royce P.M., and Steinmann B. (Eds), Wiley
    • Morris N.P., et al. Morphology and chemical composition of connective tissue: cartilage. In: Royce P.M., and Steinmann B. (Eds). Connective Tissue and its Heritable Disorders. 2nd edn (2002), Wiley 41-66
    • (2002) Connective Tissue and its Heritable Disorders. 2nd edn , pp. 41-66
    • Morris, N.P.1
  • 22
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg H.M. Developmental regulation of the growth plate. Nature 423 (2003) 332-336
    • (2003) Nature , vol.423 , pp. 332-336
    • Kronenberg, H.M.1
  • 23
    • 1642545091 scopus 로고    scopus 로고
    • Essential role of hypertrophic chondrocytes in endochondral bone development
    • Chung U.I. Essential role of hypertrophic chondrocytes in endochondral bone development. Endocr. J. 51 (2004) 19-24
    • (2004) Endocr. J. , vol.51 , pp. 19-24
    • Chung, U.I.1
  • 24
    • 1842611651 scopus 로고    scopus 로고
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton
    • Long F., et al. Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development 131 (2004) 1309-1318
    • (2004) Development , vol.131 , pp. 1309-1318
    • Long, F.1
  • 25
    • 16844370419 scopus 로고    scopus 로고
    • Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development
    • Colnot C., et al. Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development 132 (2005) 1057-1067
    • (2005) Development , vol.132 , pp. 1057-1067
    • Colnot, C.1
  • 26
    • 33746900467 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation
    • Jacob A.L., et al. Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev. Biol. 296 (2006) 315-328
    • (2006) Dev. Biol. , vol.296 , pp. 315-328
    • Jacob, A.L.1
  • 27
    • 0034772675 scopus 로고    scopus 로고
    • Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains
    • Wang Q., et al. Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains. Development 128 (2001) 3867-3876
    • (2001) Development , vol.128 , pp. 3867-3876
    • Wang, Q.1
  • 28
    • 33846566729 scopus 로고    scopus 로고
    • Fibroblast growth factor expression in the postnatal growth plate
    • Lazarus J.E., et al. Fibroblast growth factor expression in the postnatal growth plate. Bone 40 (2007) 577-586
    • (2007) Bone , vol.40 , pp. 577-586
    • Lazarus, J.E.1
  • 29
    • 33847225869 scopus 로고    scopus 로고
    • Fibroblast growth factors 1, 2, 17, and 19 are the predominant FGF ligands expressed in human fetal growth plate cartilage
    • Krejci P., et al. Fibroblast growth factors 1, 2, 17, and 19 are the predominant FGF ligands expressed in human fetal growth plate cartilage. Pediatr. Res 61 (2007) 267-272
    • (2007) Pediatr. Res , vol.61 , pp. 267-272
    • Krejci, P.1
  • 30
    • 57349101756 scopus 로고    scopus 로고
    • Regulation of articular chondrocyte proliferation and differentiation by Indian hedgehog and parathyroid hormone-related protein in mice
    • Chen X., et al. Regulation of articular chondrocyte proliferation and differentiation by Indian hedgehog and parathyroid hormone-related protein in mice. Arthritis Rheum. 58 (2008) 3788-3797
    • (2008) Arthritis Rheum. , vol.58 , pp. 3788-3797
    • Chen, X.1
  • 31
    • 46749111932 scopus 로고    scopus 로고
    • Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy
    • Mak K.K., et al. Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development 135 (2008) 1947-1956
    • (2008) Development , vol.135 , pp. 1947-1956
    • Mak, K.K.1
  • 32
    • 34447288267 scopus 로고    scopus 로고
    • Achondroplasia
    • Horton W.A., et al. Achondroplasia. Lancet 370 (2007) 162-172
    • (2007) Lancet , vol.370 , pp. 162-172
    • Horton, W.A.1
  • 33
    • 0036744820 scopus 로고    scopus 로고
    • Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation
    • Minina E., et al. Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation. Dev. Cell 3 (2002) 439-449
    • (2002) Dev. Cell , vol.3 , pp. 439-449
    • Minina, E.1
  • 34
    • 0034234569 scopus 로고    scopus 로고
    • A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos
    • Iwata T., et al. A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos. Hum. Mol. Genet. 9 (2000) 1603-1613
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1603-1613
    • Iwata, T.1
  • 35
    • 0036205735 scopus 로고    scopus 로고
    • FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
    • Ohbayashi N., et al. FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 16 (2002) 870-879
    • (2002) Genes Dev. , vol.16 , pp. 870-879
    • Ohbayashi, N.1
  • 36
    • 0036203355 scopus 로고    scopus 로고
    • Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
    • Liu Z., et al. Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 16 (2002) 859-869
    • (2002) Genes Dev. , vol.16 , pp. 859-869
    • Liu, Z.1
  • 37
    • 33751106713 scopus 로고    scopus 로고
    • Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium
    • Hinoi E., et al. Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 20 (2006) 2937-2942
    • (2006) Genes Dev. , vol.20 , pp. 2937-2942
    • Hinoi, E.1
  • 38
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    • St-Jacques B., et al. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 13 (1999) 2072-2086
    • (1999) Genes Dev. , vol.13 , pp. 2072-2086
    • St-Jacques, B.1
  • 39
    • 22644447278 scopus 로고    scopus 로고
    • Regulation of skeletal development by the Runx family of transcription factors
    • Komori T. Regulation of skeletal development by the Runx family of transcription factors. J. Cell. Biochem. 95 (2005) 445-453
    • (2005) J. Cell. Biochem. , vol.95 , pp. 445-453
    • Komori, T.1
  • 40
    • 34347400475 scopus 로고    scopus 로고
    • Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function
    • Shimoyama A., et al. Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol. Biol. Cell 18 (2007) 2411-2418
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2411-2418
    • Shimoyama, A.1
  • 41
    • 33846214070 scopus 로고    scopus 로고
    • FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate
    • Liu Z., et al. FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev. Biol. 302 (2007) 80-91
    • (2007) Dev. Biol. , vol.302 , pp. 80-91
    • Liu, Z.1
  • 42
    • 34347248067 scopus 로고    scopus 로고
    • FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod
    • Hung I.H., et al. FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev. Biol. 307 (2007) 300-313
    • (2007) Dev. Biol. , vol.307 , pp. 300-313
    • Hung, I.H.1
  • 43
    • 0038782306 scopus 로고    scopus 로고
    • Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
    • Yu K., et al. Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130 (2003) 3063-3074
    • (2003) Development , vol.130 , pp. 3063-3074
    • Yu, K.1
  • 44
    • 0033151612 scopus 로고    scopus 로고
    • FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
    • Sahni M., et al. FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev. 13 (1999) 1361-1366
    • (1999) Genes Dev. , vol.13 , pp. 1361-1366
    • Sahni, M.1
  • 45
    • 0032938128 scopus 로고    scopus 로고
    • A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors
    • Li C., et al. A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Hum. Mol. Genet. 8 (1999) 35-44
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 35-44
    • Li, C.1
  • 46
    • 1042289662 scopus 로고    scopus 로고
    • Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype
    • Murakami S., et al. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes Dev. 18 (2004) 290-305
    • (2004) Genes Dev. , vol.18 , pp. 290-305
    • Murakami, S.1
  • 47
    • 31044432518 scopus 로고    scopus 로고
    • Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation
    • Zhang R., et al. Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 365-370
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 365-370
    • Zhang, R.1
  • 48
    • 0030896404 scopus 로고    scopus 로고
    • Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
    • Su W.C., et al. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature 386 (1997) 288-292
    • (1997) Nature , vol.386 , pp. 288-292
    • Su, W.C.1
  • 49
    • 0038491622 scopus 로고    scopus 로고
    • A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation
    • Dailey L., et al. A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation. J. Cell Biol. 161 (2003) 1053-1066
    • (2003) J. Cell Biol. , vol.161 , pp. 1053-1066
    • Dailey, L.1
  • 50
    • 32244446690 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling
    • Ben-Zvi T., et al. Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling. J. Cell Sci. 119 (2006) 380-387
    • (2006) J. Cell Sci. , vol.119 , pp. 380-387
    • Ben-Zvi, T.1
  • 51
    • 36549064806 scopus 로고    scopus 로고
    • Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias
    • de Frutos C.A., et al. Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias. Dev. Cell 13 (2007) 872-883
    • (2007) Dev. Cell , vol.13 , pp. 872-883
    • de Frutos, C.A.1
  • 52
    • 19444368174 scopus 로고    scopus 로고
    • C-type natriuretic peptide and guanylyl cyclase B receptor
    • Schulz S. C-type natriuretic peptide and guanylyl cyclase B receptor. Peptides 26 (2005) 1024-1034
    • (2005) Peptides , vol.26 , pp. 1024-1034
    • Schulz, S.1
  • 53
    • 27944483696 scopus 로고    scopus 로고
    • Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis
    • Krejci P., et al. Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis. J. Cell Sci. 118 (2005) 5089-5100
    • (2005) J. Cell Sci. , vol.118 , pp. 5089-5100
    • Krejci, P.1
  • 54
    • 11144358656 scopus 로고    scopus 로고
    • Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway
    • Yasoda A., et al. Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway. Nat. Med. 10 (2004) 80-86
    • (2004) Nat. Med. , vol.10 , pp. 80-86
    • Yasoda, A.1
  • 55
    • 34248512085 scopus 로고    scopus 로고
    • Mineralized tissue cells are a principal source of FGF23
    • Yoshiko Y., et al. Mineralized tissue cells are a principal source of FGF23. Bone 40 (2007) 1565-1573
    • (2007) Bone , vol.40 , pp. 1565-1573
    • Yoshiko, Y.1
  • 56
    • 34250649644 scopus 로고    scopus 로고
    • The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis
    • Razzaque M.S., and Lanske B. The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis. J. Endocrinol. 194 (2007) 1-10
    • (2007) J. Endocrinol. , vol.194 , pp. 1-10
    • Razzaque, M.S.1    Lanske, B.2
  • 57
    • 58349115748 scopus 로고    scopus 로고
    • The Klotho gene family as a regulator of endocrine fibroblast growth factors
    • Kurosu H., and Kuro O.M. The Klotho gene family as a regulator of endocrine fibroblast growth factors. Mol. Cell. Endocrinol. 299 (2008) 72-78
    • (2008) Mol. Cell. Endocrinol. , vol.299 , pp. 72-78
    • Kurosu, H.1    Kuro, O.M.2
  • 58
    • 1642416884 scopus 로고    scopus 로고
    • Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
    • Shimada T., et al. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J. Clin. Invest. 113 (2004) 561-568
    • (2004) J. Clin. Invest. , vol.113 , pp. 561-568
    • Shimada, T.1
  • 59
    • 50849104780 scopus 로고    scopus 로고
    • Genetic evidence of serum phosphate-independent functions of FGF-23 on bone
    • Sitara D., et al. Genetic evidence of serum phosphate-independent functions of FGF-23 on bone. PLoS Genet. 4 (2008) e1000154
    • (2008) PLoS Genet. , vol.4
    • Sitara, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.