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Volumn 40, Issue 4, 2012, Pages 870-874

Role of splice variants in the metastatic progression of prostate cancer

Author keywords

Alternative splicing; Central alternative exon; Epidermal growth factor; Metastasis; Prolactin; Prostate cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROLACTIN RECEPTOR;

EID: 84864383743     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20120026     Document Type: Conference Paper
Times cited : (29)

References (50)
  • 1
    • 0018848546 scopus 로고
    • Synthesis of secreted and membrane-bound immunoglobulin Mu heavy chains is directed by mRNAs that differ at their 3' ends
    • Alt, F.W., Bothwell, A.L., Knapp, M., Siden, E., Mather, E., Koshland, M. and Baltimore, D. (1980) Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends. Cell 20, 293-301 (Pubitemid 10117745)
    • (1980) Cell , vol.20 , Issue.2 , pp. 293-301
    • Alt, F.W.1    Bothwell, A.L.M.2    Knapp, M.3
  • 2
    • 0018896724 scopus 로고
    • Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways
    • Early, P., Rogers, J., Davis, M., Calame, K., Bond, M., Wall, R. and Hood, L. (1980) Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways. Cell 20, 313-319 (Pubitemid 10117747)
    • (1980) Cell , vol.20 , Issue.2 , pp. 313-319
    • Early, P.1    Rogers, J.2    Davis, M.3
  • 3
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium
    • International Human Genome Sequencing Consortium (2004) Finishing the euchromatic sequence of the human genome. Nature 431, 931-945
    • (2004) Nature , vol.431 , pp. 931-945
  • 4
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan, Q., Shai, O., Lee, L.J., Frey, B.J. and Blencowe, B.J. (2008) Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nature Genet. 40, 1413-1415
    • (2008) Nature Genet. , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 6
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
    • David, C.J. and Manley, J.L. (2010) Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev. 24, 2343-2364
    • (2010) Genes Dev. , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 7
    • 60349104299 scopus 로고    scopus 로고
    • The spliceosome: Design principles of a dynamic RNP machine
    • Wahl, M.C., Will, C.L. and Luhrmann, R. (2009) The spliceosome: design principles of a dynamic RNP machine. Cell 136, 701-718
    • (2009) Cell , vol.136 , pp. 701-718
    • Wahl, M.C.1    Will, C.L.2    Luhrmann, R.3
  • 8
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: New insights from global analyses
    • Blencowe, B.J. (2006) Alternative splicing: new insights from global analyses. Cell 126, 37-47
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 9
    • 75849145292 scopus 로고    scopus 로고
    • Expansion of the eukaryotic proteome by alternative splicing
    • Nilsen, T.W. and Graveley, B.R. (2010) Expansion of the eukaryotic proteome by alternative splicing. Nature 463, 457-463
    • (2010) Nature , vol.463 , pp. 457-463
    • Nilsen, T.W.1    Graveley, B.R.2
  • 10
    • 21244439380 scopus 로고    scopus 로고
    • Regulation of apoptosis by alternative pre-mRNA splicing
    • DOI 10.1016/j.molcel.2005.05.026, PII S1097276505013754
    • Schwerk, C. and Schulze-Osthoff, K. (2005) Regulation of apoptosis by alternative pre-mRNA splicing. Mol. Cell 19, 1-13 (Pubitemid 40884653)
    • (2005) Molecular Cell , vol.19 , Issue.1 , pp. 1-13
    • Schwerk, C.1    Schulze-Osthoff, K.2
  • 11
    • 0034161419 scopus 로고    scopus 로고
    • Exonic splicing enhancers: Mechanism of action, diversity and role in human genetic diseases
    • Blencowe, B.J. (2000) Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases. Trends Biochem. Sci. 25, 106-110
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 106-110
    • Blencowe, B.J.1
  • 12
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • Black, D.L. (2003) Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72, 291-336
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 291-336
    • Black, D.L.1
  • 14
    • 34447106755 scopus 로고    scopus 로고
    • Alternative splicing in cancer: Noise, functional, or systematic?
    • Skotheim, R.I. and Nees, M. (2007) Alternative splicing in cancer: noise, functional, or systematic? Int. J. Biochem. Cell Biol. 39, 1432-1449
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 1432-1449
    • Skotheim, R.I.1    Nees, M.2
  • 15
    • 33746927884 scopus 로고    scopus 로고
    • The connection between splicing and cancer
    • DOI 10.1242/jcs.03053
    • Srebrow, A. and Kornblihtt, A.R. (2006) The connection between splicing and cancer. J. Cell Sci. 119, 2635-2641 (Pubitemid 44184000)
    • (2006) Journal of Cell Science , vol.119 , Issue.13 , pp. 2635-2641
    • Srebrow, A.1    Kornblihtt, A.R.2
  • 16
    • 37349089805 scopus 로고    scopus 로고
    • Insights into the connection between cancer and alternative splicing
    • DOI 10.1016/j.tig.2007.10.001, PII S0168952507003459
    • Kim, E., Goren, A. and Ast, G. (2008) Insights into the connection between cancer and alternative splicing. Trends Genet. 24, 7-10 (Pubitemid 350298628)
    • (2008) Trends in Genetics , vol.24 , Issue.1 , pp. 7-10
    • Kim, E.1    Goren, A.2    Ast, G.3
  • 17
    • 17244377195 scopus 로고    scopus 로고
    • Bioinformatics analysis of alternative splicing
    • DOI 10.1093/bib/6.1.23
    • Lee, C. and Wang, Q. (2005) Bioinformatics analysis of alternative splicing. Brief. Bioinform. 6, 23-33 (Pubitemid 40528577)
    • (2005) Briefings in Bioinformatics , vol.6 , Issue.1 , pp. 23-33
    • Lee, C.1    Wang, Q.2
  • 18
    • 60549113531 scopus 로고    scopus 로고
    • Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays
    • Kechris, K., Yang, Y.H. and Yeh, R.F. (2008) Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays. BMC Genomics 9, 551
    • (2008) BMC Genomics , vol.9 , pp. 551
    • Kechris, K.1    Yang, Y.H.2    Yeh, R.F.3
  • 20
    • 64249084287 scopus 로고    scopus 로고
    • Aberrant RNA splicing and its functional consequences in cancer cells
    • Fackenthal, J.D. and Godley, L.A. (2008) Aberrant RNA splicing and its functional consequences in cancer cells. Dis. Models Mech. 1, 37-42
    • (2008) Dis. Models Mech. , vol.1 , pp. 37-42
    • Fackenthal, J.D.1    Godley, L.A.2
  • 21
    • 33947305594 scopus 로고    scopus 로고
    • Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay
    • DOI 10.1101/gad.1525507
    • Ni, J.Z., Grate, L., Donohue, J.P., Preston, C., Nobida, N., O'Brien, G., Shiue, L., Clark, T.A., Blume, J.E. and Ares, Jr, M. (2007) Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay. Genes Dev. 21, 708-718 (Pubitemid 46440292)
    • (2007) Genes and Development , vol.21 , Issue.6 , pp. 708-718
    • Ni, J.Z.1    Grate, L.2    Donohue, J.P.3    Preston, C.4    Nobida, N.5    O'Brien, G.6    Shiue, L.7    Clark, T.A.8    Blume, J.E.9    Ares Jr., M.10
  • 22
    • 70350569286 scopus 로고    scopus 로고
    • Mechanisms of alternative splicing regulation: Insights from molecular and genomics approaches
    • Chen, M. and Manley, J.L. (2009) Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat. Rev. Mol. Cell Biol. 10, 741-754
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 741-754
    • Chen, M.1    Manley, J.L.2
  • 26
    • 77955077505 scopus 로고    scopus 로고
    • Molecular aspects of tumor cell migration and invasion
    • Bozzuto, G., Ruggieri, P. and Molinari, A. (2010) Molecular aspects of tumor cell migration and invasion. Ann. Ist. Super. Sanita 46, 66-80
    • (2010) Ann. Ist. Super. Sanita , vol.46 , pp. 66-80
    • Bozzuto, G.1    Ruggieri, P.2    Molinari, A.3
  • 29
    • 34548404242 scopus 로고    scopus 로고
    • Proteases, growth factors, chemokines, and the microenvironment in prostate cancer bone metastasis
    • DOI 10.1016/j.urolonc.2007.05.008, PII S107814390700141X, Proceedings: Annual Meeting of the Society of Urologic Oncology (May 2006). Part I: Genitourinary Cancer Biology and Translation
    • Bonfil, R.D., Chinni, S., Fridman, R., Kim, H.R. and Cher, M.L. (2007) Proteases, growth factors, chemokines, and the microenvironment in prostate cancer bone metastasis. Urol. Oncol. 25, 407-411 (Pubitemid 47362762)
    • (2007) Urologic Oncology: Seminars and Original Investigations , vol.25 , Issue.5 , pp. 407-411
    • Bonfil, R.D.1    Chinni, S.2    Fridman, R.3    Kim, H.-R.4    Cher, M.L.5
  • 30
    • 34447264104 scopus 로고    scopus 로고
    • The role of tumor microenvironment in prostate cancer bone metastasis
    • DOI 10.1002/jcb.21214
    • Morrissey, C. and Vessella, R.L. (2007) The role of tumor microenvironment in prostate cancer bone metastasis. J. Cell. Biochem. 101, 873-886 (Pubitemid 47040869)
    • (2007) Journal of Cellular Biochemistry , vol.101 , Issue.4 , pp. 873-886
    • Morrissey, C.1    Vessella, R.L.2
  • 34
    • 77956290679 scopus 로고    scopus 로고
    • FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells
    • Gupta, S., Iljin, K., Sara, H., Mpindi, J.P., Mirtti, T., Vainio, P., Rantala, J., Alanen, K., Nees, M. and Kallioniemi, O. (2010) FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells. Cancer Res. 70, 6735-6745
    • (2010) Cancer Res. , vol.70 , pp. 6735-6745
    • Gupta, S.1    Iljin, K.2    Sara, H.3    Mpindi, J.P.4    Mirtti, T.5    Vainio, P.6    Rantala, J.7    Alanen, K.8    Nees, M.9    Kallioniemi, O.10
  • 36
    • 54249154706 scopus 로고    scopus 로고
    • Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts
    • Wang, J., Cai, Y., Yu, W., Ren, C., Spencer, D.M. and Ittmann, M. (2008) Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts. Cancer Res. 68, 8516-8524
    • (2008) Cancer Res. , vol.68 , pp. 8516-8524
    • Wang, J.1    Cai, Y.2    Yu, W.3    Ren, C.4    Spencer, D.M.5    Ittmann, M.6
  • 37
    • 0346789073 scopus 로고    scopus 로고
    • Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16
    • DOI 10.1016/j.gene.2003.09.047
    • Owczarek, C.M., Portbury, K.J., Hardy, M.P., O'Leary, D.A., Kudoh, J., Shibuya, K., Shimizu, N., Kola, I. and Hertzog, P.J. (2004) Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16. Gene 324, 65-77 (Pubitemid 38030326)
    • (2004) Gene , vol.324 , Issue.1-2 , pp. 65-77
    • Owczarek, C.M.1    Portbury, K.J.2    Hardy, M.P.3    O'Leary, D.A.4    Kudoh, J.5    Shibuya, K.6    Shimizu, N.7    Kola, I.8    Hertzog, P.J.9
  • 39
    • 80053333146 scopus 로고    scopus 로고
    • Prolactin in breast and prostate cancer: Molecular and genetic perspectives
    • Jacobson, E.M., Hugo, E.R., Borcherding, D.C. and Ben-Jonathan, N. (2011) Prolactin in breast and prostate cancer: molecular and genetic perspectives. Discovery Med. 11, 315-324
    • (2011) Discovery Med. , vol.11 , pp. 315-324
    • Jacobson, E.M.1    Hugo, E.R.2    Borcherding, D.C.3    Ben-Jonathan, N.4
  • 40
    • 0035798602 scopus 로고    scopus 로고
    • Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11
    • Hu, Z.Z., Meng, J. and Dufau, M.L. (2001) Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11. J. Biol. Chem. 276, 41086-41094
    • (2001) J. Biol. Chem. , vol.276 , pp. 41086-41094
    • Hu, Z.Z.1    Meng, J.2    Dufau, M.L.3
  • 41
    • 0037294370 scopus 로고    scopus 로고
    • Alternative splicing to exon 11 of human prolactin receptor gene results in multiple isoforms including a secreted prolactin-binding protein
    • DOI 10.1677/jme.0.0300031
    • Trott, J.F., Hovey, R.C., Koduri, S. and Vonderhaar, B.K. (2003) Alternative splicing to exon 11 of human prolactin receptor gene results in multiple isoforms including a secreted prolactin-binding protein. J. Mol. Endocrinol. 30, 31-47 (Pubitemid 36305254)
    • (2003) Journal of Molecular Endocrinology , vol.30 , Issue.1 , pp. 31-47
    • Trott, J.F.1    Hovey, R.C.2    Koduri, S.3    Vonderhaar, B.K.4
  • 42
    • 79955865397 scopus 로고    scopus 로고
    • Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity
    • Wang, H., Zhou, M., Shi, B., Zhang, Q., Jiang, H., Sun, Y., Liu, J., Zhou, K., Yao, M., Gu, J. et al. (2011) Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity. Neoplasia 13, 461-471
    • (2011) Neoplasia , vol.13 , pp. 461-471
    • Wang, H.1    Zhou, M.2    Shi, B.3    Zhang, Q.4    Jiang, H.5    Sun, Y.6    Liu, J.7    Zhou, K.8    Yao, M.9    Gu, J.10
  • 43
    • 23844481360 scopus 로고    scopus 로고
    • S179D prolactin increases vitamin D receptor and p21 through up-regulation of short 1b prolactin receptor in human prostate cancer cells
    • DOI 10.1158/0008-5472.CAN-04-3350
    • Wu, W., Ginsburg, E., Vonderhaar, B.K. and Walker, A.M. (2005) S179D prolactin increases vitamin D receptor and p21 through up-regulation of short 1b prolactin receptor in human prostate cancer cells. Cancer Res. 65, 7509-7515 (Pubitemid 41161287)
    • (2005) Cancer Research , vol.65 , Issue.16 , pp. 7509-7515
    • Wu, W.1    Ginsburg, E.2    Vonderhaar, B.K.3    Walker, A.M.4
  • 44
    • 72849112323 scopus 로고    scopus 로고
    • Long term increased expression of the short form 1b prolactin receptor in PC-3 human prostate cancer cells decreases cell growth and migration, and causes multiple changes in gene expression consistent with reduced invasive capacity
    • Huang, K.T. and Walker, A.M. (2010) Long term increased expression of the short form 1b prolactin receptor in PC-3 human prostate cancer cells decreases cell growth and migration, and causes multiple changes in gene expression consistent with reduced invasive capacity. Prostate 70, 37-47
    • (2010) Prostate , vol.70 , pp. 37-47
    • Huang, K.T.1    Walker, A.M.2
  • 46
    • 34247217230 scopus 로고    scopus 로고
    • Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
    • DOI 10.1038/sj.bjc.6603700, PII 6603700
    • Yates, C.C., Shepard, C.R., Stolz, D.B. and Wells, A. (2007) Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. Br. J. Cancer 96, 1246-1252 (Pubitemid 46625074)
    • (2007) British Journal of Cancer , vol.96 , Issue.8 , pp. 1246-1252
    • Yates, C.C.1    Shepard, C.R.2    Stolz, D.B.3    Wells, A.4
  • 47
  • 48
    • 84855408587 scopus 로고    scopus 로고
    • Growth and metastasis suppression of glioma xenografts expressing exon 4-deletion variant of epidermal growth factor receptor by monoclonal antibody CH12-mediated receptor degradation
    • Wang, H., Shi, B., Zhang, Q., Jiang, H., Hu, S., Kong, J., Yao, M., Yang, S. and Li, Z. (2012) Growth and metastasis suppression of glioma xenografts expressing exon 4-deletion variant of epidermal growth factor receptor by monoclonal antibody CH12-mediated receptor degradation. FASEB J. 26, 73-80
    • (2012) FASEB J. , vol.26 , pp. 73-80
    • Wang, H.1    Shi, B.2    Zhang, Q.3    Jiang, H.4    Hu, S.5    Kong, J.6    Yao, M.7    Yang, S.8    Li, Z.9
  • 49
    • 0141974926 scopus 로고    scopus 로고
    • Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences
    • DOI 10.1093/nar/gkg786
    • Xu, Q. and Lee, C. (2003) Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences. Nucleic Acids Res. 31, 5635-5643 (Pubitemid 37441935)
    • (2003) Nucleic Acids Research , vol.31 , Issue.19 , pp. 5635-5643
    • Xu, Q.1    Lee, C.2
  • 50
    • 74549154452 scopus 로고    scopus 로고
    • Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
    • Das, S., Becker, B.N., Hoffmann, F.M. and Mertz, J.E. (2009) Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway. BMC Cell Biol. 10, 94
    • (2009) BMC Cell Biol. , vol.10 , pp. 94
    • Das, S.1    Becker, B.N.2    Hoffmann, F.M.3    Mertz, J.E.4


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