Growth and metastasis suppression of glioma xenografts expressing exon 4-deletion variant of epidermal growth factor receptor by monoclonal antibody CH12-mediated receptor degradation

FASEB Journal

Volumn 26, Issue 1, 2012, Pages 73-80

  Wang, Hai ^a   Shi, Bizhi ^a   Zhang, Qingli ^b   Jiang, Hua ^a   Hu, Suwen ^a   Kong, Juan ^a   Yao, Ming ^a   Yang, Shengli ^a   Li, Zonghai ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

C225; LAMP 1; Target therapy

Indexed keywords

CETUXIMAB; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CH12; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P27; UNCLASSIFIED DRUG; UVOMORULIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; EXON; FEMALE; FOOD AND DRUG ADMINISTRATION; GENE DELETION; GENE EXPRESSION; GENETIC VARIABILITY; GLIOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR GROWTH; UPREGULATION; XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; EXONS; FEMALE; GENE DELETION; GLIOMA; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MICE; MICE, NUDE; RECEPTOR, EPIDERMAL GROWTH FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84855408587     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-191064     Document Type: Article

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