Southwest Oncology Group phase II study of irinotecan in patients with advanced transitional cell carcinoma of the urothelium that progressed after platinum-based chemotherapy

Clinical Genitourinary Cancer

Volumn 6, Issue 1, 2008, Pages 36-39

  Beer, Tomasz M ^a   Goldman, Bryan ^b   Nichols, Craig R ^c   Petrylak, Daniel P ^d   Agarwal, Manoj ^e   Ryan, Christopher W ^a   Crawford, E David ^f  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b SOUTHWEST ONCOLOGY GROUP STATISTICAL CENTER   (United States)

^c Providence Cancer Center   (United States)

^d NewYork Presbyterian Hospital   (United States)

^e UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^f UNIVERSITY OF COLORADO   (United States)

Author keywords

Carboplatin; Cisplatin; Metastasis

Indexed keywords

DEXAMETHASONE; IRINOTECAN; SEROTONIN 3 ANTAGONIST;

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; ALOPECIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER METASTASIS; BLOOD TOXICITY; CANCER GROWTH; CANCER PATIENT; CANCER RESISTANCE; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEHYDRATION; DIARRHEA; DISEASE COURSE; DISEASE FREE SURVIVAL; DRUG SAFETY; FATIGUE; FEMALE; HUMAN; HYPOALBUMINEMIA; LYMPHOCYTOPENIA; MALE; MULTIPLE CYCLE TREATMENT; NAUSEA; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; PROSPECTIVE STUDY; SURVIVAL RATE; SURVIVAL TIME; THERAPY EFFECT; TRANSITIONAL CELL CARCINOMA; TREATMENT OUTCOME; TREATMENT RESPONSE; UROGENITAL TRACT INFECTION; VOMITING;

EID: 43249131172     PISSN: 15587673     EISSN: None     Source Type: Journal    
DOI: 10.3816/CGC.2008.n.006     Document Type: Article

References (17)

1. PJ Loehrer Sr LH Einhorn PJ Elson A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study [published erratum appears in J Clin Oncol 1993; 11:384] J Clin Oncol 10 1992 1066 1073
2. CJ Logothetis FH Dexeus L Finn A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors J Clin Oncol 8 1990 1050 1055
3. H Von der Maase SW Hansen JT Roberts Gemcitabine and cisplatin (GC) versus methotrexate, vinblastine, adriamycin and cisplatin (MVAC) chemotherapy in advanced or metastatic transitional cell carcinoma (TCC) of the urothelium: a large randomized multicenter, multinational phase III study Proc Am Soc Clin Oncol 2000 329a (Abstract 1292).
4. NL Geller CN Sternberg D Penenberg Prognostic factors for survival of patients with advanced urothelial tumors treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy Cancer 67 1991 1525 1531
5. V Gebbia A Testa N Borsellino Single agent 2',2'-difluorodeoxycytidine in the treatment of metastatic urothelial carcinoma: a phase II study Clin Ter 150 1999 11 15
6. V Lorusso CF Pollera M Antimi A phase II study of gemcitabine in patients with transitional cell carcinoma of the urinary tract previously treated with platinum. Italian Co-operative Group on Bladder Cancer Eur J Cancer 34 1998 1208 1212
7. TE Keane RE El-Galley C Sun Camptothecin analogues/cisplatin: an effective treatment of advanced bladder cancer in a preclinical in vivo model system J Urol 160 1998 252 256
8. HR Bahadori CM Rocha Lima MR Green Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small cell lung cancer cell lines Anticancer Res 19 1999 5423 5428
9. P Therasse SG Arbuck EA Eisenhauer New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl Cancer Inst 92 2000 205 216
10. DJ Vaughn CM Broome M Hussain Phase II trial of weekly paclitaxel in patients with previously treated advanced urothelial cancer J Clin Oncol 20 2002 937 940
11. JA McCaffrey S Hilton M Mazumdar Phase II trial of docetaxel in patients with advanced or metastatic transitional-cell carcinoma J Clin Oncol 15 1997 1853 1857
12. RS Witte P Elson B Bono Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma J Clin Oncol 15 1997 589 593
13. CJ Sweeney BJ Roth FF Kabbinavar Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium J Clin Oncol 24 2006 3451 3457
14. MD Galsky S Mironov A Iasonos Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma Invest New Drugs 25 2007 265 270
15. S Culine C Theodore M De Santis A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen Br J Cancer 94 2006 1395 1401
16. RS Witte J Manola PA Burch Topotecan in previously treated advanced urothelial carcinoma: an ECOG phase II trial Invest New Drugs 16 1998 191 195
17. MJ de Jonge JP Droz L Paz-Ares Phase II study on 9-nitrocamptothecin (RFS 2000) in patients with advanced or metastatic urothelial tract tumors Invest New Drugs 22 2004 329 333