The skeletal muscle wnt pathway may modulate insulin resistance and muscle development in a diet-induced obese rat model

Obesity

Volumn 20, Issue 8, 2012, Pages 1577-1584

  Zhou, Dan ^a   Strakovsky, Rita S ^a   Zhang, Xiyuan ^a   Pan, Yuan Xiang ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR SUBSTRATE; MYOCYTE ENHANCER FACTOR 2; MYOGENIC FACTOR; MYOGENIC FACTOR 3; MYOGENIC FACTOR 5; PROTEIN KINASE B; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; WNT PROTEIN; WNT1 PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; ENZYME ACTIVITY; ENZYME REGULATION; GASTROCNEMIUS MUSCLE; GENE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID STORAGE; MALE; MUSCLE DEVELOPMENT; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; WNT SIGNALING PATHWAY; WNT1 GENE; WNT3A GENE; WNT5A GENE;

ADIPOSE TISSUE; ANIMALS; BETA CATENIN; BODY WEIGHT; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE TRANSPORTER TYPE 4; INSULIN RESISTANCE; MALE; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; MYOGENIC REGULATORY FACTORS; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; SPECIES SPECIFICITY; TRIGLYCERIDES; WNT SIGNALING PATHWAY;

ANIMALIA; RATTUS;

EID: 84864366527     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2012.42     Document Type: Article

References (40)

1. Speakman Jr. Obesity: the integrated roles of environment and genetics. J Nutr 2004;134:2090S-2105S.
2. Abou Mrad J, Yakubu F, Lin D et al. Skeletal muscle composition in dietary obesity-susceptible and dietary obesity-resistant rats. Am J Physiol 1992;262:R684-R688.
3. Levin BE, Dunn-Meynell AA, Balkan B, Keesey RE. Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats. Am J Physiol 1997;273:R725-R730.
4. Blaak EE. Metabolic fluxes in skeletal muscle in relation to obesity and insulin resistance. Best Pract Res Clin Endocrinol Metab 2005;19:391-403.
5. Laudes M. Role of WNT signalling in the determination of human mesenchymal stem cells into preadipocytes. J Mol Endocrinol 2011;46:R65-R72.
6. Kanazawa A, Tsukada S, Sekine A et al. Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes. Am J Hum Genet 2004;75:832-843.
7. Grant SF, Thorleifsson G, Reynisdottir I et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006;38:320-323.
8. Abiola M, Favier M, Christodoulou-Vafeiadou E et al. Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells. PLoS ONE 2009;4:e8509.
9. Shang YC, Zhang C, Wang SH et al. Activated beta-catenin induces myogenesis and inhibits adipogenesis in BM-derived mesenchymal stromal cells. Cytotherapy 2007;9:667-681.
10. Du M, Yin J, Zhu MJ. Cellular signaling pathways regulating the initial stage of adipogenesis and marbling of skeletal muscle. Meat Sci 2010;86:103-109.
11. Scarda A, Franzin C, Milan G et al. Increased adipogenic conversion of muscle satellite cells in obese Zucker rats. Int J Obes (Lond) 2010;34:1319-1327.
12. Chang S, Graham B, Yakubu F et al. Metabolic differences between obesityprone and obesity-resistant rats. Am J Physiol 1990;259:R1103-R1110.
13. Moraes RC, Blondet A, Birkenkamp-Demtroeder K et al. Study of the alteration of gene expression in adipose tissue of diet-induced obese mice by microarray and reverse transcription-polymerase chain reaction analyses. Endocrinology 2003;144:4773-4782.
14. Kim DH, Choi JW, Joo JI et al. Changes in expression of skeletal muscle proteins between obesity-prone and obesity-resistant rats induced by a high-fat diet. J Proteome Res 2011;10:1281-1292.
15. Eckardt K, Taube A, Eckel J. Obesity-associated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity. Rev Endocr Metab Disord 2011;12:163-172.
16. Ivy JL. Muscle insulin resistance amended with exercise training: role of GLUT4 expression. Med Sci Sports Exerc 2004;36:1207-1211.
17. Tsika RW, Schramm C, Simmer G et al. Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype. J Biol Chem 2008;283:36154-36167.
18. Steelman CA, Recknor JC, Nettleton D, Reecy JM. Transcriptional profiling of myostatin-knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy. FASEB J 2006;20:580-582.
19. Ben-Ze'ev A, Shtutman M, Zhurinsky J. The integration of cell adhesion with gene expression: the role of beta-catenin. Exp Cell Res 2000;261:75-82.
20. King PA, Horton ED, Hirshman MF, Horton ES. Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation. J Clin Invest 1992;90:1568-1575.
21. Anubhuti, Arora S. Leptin and its metabolic interactions: an update. Diabetes Obes Metab 2008;10:973-993.
22. Yamauchi T, Tobe K, Tamemoto H et al. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice. Mol Cell Biol 1996;16:3074-3084.
23. Bommer GT, Feng Y, Iura A et al. IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype. J Biol Chem 2010;285:1928-1938.
24. Choi K, Kim YB. Molecular mechanism of insulin resistance in obesity and type 2 diabetes. Korean J Intern Med 2010;25:119-129.
25. Houseknecht KL, Portocarrero CP. Leptin and its receptors: regulators of whole-body energy homeostasis. Domest Anim Endocrinol 1998;15:457-475.
26. Ohba S, Lanigan TM, Roessler BJ. Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes. Osteoarthr Cartil 2010;18:1620-1629.
27. Kahn BB. Lilly lecture 1995. Glucose transport: pivotal step in insulin action. Diabetes 1996;45:1644-1654.
28. van Dam EM, Govers R, James DE. Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane. Mol Endocrinol 2005;19:1067-1077.
29. Gaster M, Staehr P, Beck-Nielsen H, Schrøder HD, Handberg A. GLUT4 is reduced in slow muscle fibers of type 2 diabetic patients: is insulin resistance in type 2 diabetes a slow, type 1 fiber disease? Diabetes 2001;50:1324-1329.
30. Stannard SR, Johnson NA. Insulin resistance and elevated triglyceride in muscle: more important for survival than "thrifty" genes? J Physiol (Lond) 2004;554:595-607.
31. Armstrong DD, Esser KA. Wnt/beta-catenin signaling activates growthcontrol genes during overload-induced skeletal muscle hypertrophy. Am J Physiol, Cell Physiol 2005;289:C853-C859.
32. Tajbakhsh S, Borello U, Vivarelli E et al. Differential activation of Myf5 and MyoD by different Wnts in explants of mouse paraxial mesoderm and the later activation of myogenesis in the absence of Myf5. Development 1998;125:4155-4162.
33. Pan W, Jia Y, Wang J et al. Beta-catenin regulates myogenesis by relieving I-mfa-mediated suppression of myogenic regulatory factors in P19 cells. Proc Natl Acad Sci USA 2005;102:17378-17383.
34. Polesskaya A, Seale P, Rudnicki MA. Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell 2003;113:841-852.
35. Vettor R, Milan G, Franzin C et al. The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab 2009;297:E987-E998.
36. Berkes CA, Tapscott SJ. MyoD and the transcriptional control of myogenesis. Semin Cell Dev Biol 2005;16:585-595.
37. Wu H, Rothermel B, Kanatous S et al. Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway. EMBO J 2001;20:6414-6423.
38. Kikuchi A. Regulation of beta-catenin signaling in the Wnt pathway. Biochem Biophys Res Commun 2000;268:243-248.
39. Gartel AL, Shchors K. Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes. Exp Cell Res 2003;283:17-21.
40. Lin J, Della-Fera MA, Li C et al. P27 knockout mice: reduced myostatin in muscle and altered adipogenesis. Biochem Biophys Res Commun 2003;300:938-942.