메뉴 건너뛰기




Volumn 13, Issue 7, 2012, Pages 8364-8378

Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population

Author keywords

DNMTs; Gastric cancer (GC); Single nucleotide polymorphism (SNP); Susceptibility

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; TRDMT1 PROTEIN, HUMAN;

EID: 84864361959     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13078364     Document Type: Article
Times cited : (48)

References (53)
  • 1
    • 31144445320 scopus 로고    scopus 로고
    • Incidence and mortality of gastric cancer in China
    • Yang, L. Incidence and mortality of gastric cancer in China. World J. Gastroenterol. 2006, 12, 17-20.
    • (2006) World J. Gastroenterol , vol.12 , pp. 17-20
    • Yang, L.1
  • 4
    • 33749985758 scopus 로고    scopus 로고
    • Structure, function and mechanism of exocyclic DNA methyltransferases
    • Bheemanaik, S.; Reddy, Y.V.; Rao, D.N. Structure, function and mechanism of exocyclic DNA methyltransferases. Biochem. J. 2006, 399, 177-190.
    • (2006) Biochem. J , vol.399 , pp. 177-190
    • Bheemanaik, S.1    Reddy, Y.V.2    Rao, D.N.3
  • 5
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll, M.G.; Bestor, T.H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem. 2005, 74, 481-514.
    • (2005) Annu. Rev. Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 6
    • 0032519312 scopus 로고    scopus 로고
    • Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci
    • Liu, Y.; Oakeley, E.J.; Sun, L.; Jost, J.P. Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci. Nucleic Acids Res. 1998, 26, 1038-1045.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1038-1045
    • Liu, Y.1    Oakeley, E.J.2    Sun, L.3    Jost, J.P.4
  • 7
    • 74049130225 scopus 로고    scopus 로고
    • Solving the DNMT2 enigma
    • Schaefer, M.; Lyko, F. Solving the DNMT2 enigma. Chromosoma 2010, 119, 35-40.
    • (2010) Chromosoma , vol.119 , pp. 35-40
    • Schaefer, M.1    Lyko, F.2
  • 8
    • 0035283201 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia
    • Mizuno, S.; Chijiwa, T.; Okamura, T.; Akashi, K.; Fukumaki, Y.; Niho, Y.; Sasaki, H. Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood 2001, 97, 1172-1179.
    • (2001) Blood , vol.97 , pp. 1172-1179
    • Mizuno, S.1    Chijiwa, T.2    Okamura, T.3    Akashi, K.4    Fukumaki, Y.5    Niho, Y.6    Sasaki, H.7
  • 9
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li, E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet. 2002, 3, 662-673.
    • (2002) Nat. Rev. Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 10
    • 78049415018 scopus 로고    scopus 로고
    • DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo
    • Wienholz, B.L.; Kareta, M.S.; Moarefi, A.H.; Gordon, C.A.; Ginno, P.A.; Chedin, F. DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo. PLoS Genet. 2010, 6, e1001106.
    • (2010) PLoS Genet , vol.6
    • Wienholz, B.L.1    Kareta, M.S.2    Moarefi, A.H.3    Gordon, C.A.4    Ginno, P.A.5    Chedin, F.6
  • 11
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases DNMT3A and DNMT3B are essential for de novo methylation and mammalian development
    • Okano, M.; Bell, D.W.; Haber, D.A.; Li, E. DNA methyltransferases DNMT3A and DNMT3B are essential for de novo methylation and mammalian development. Cell 1999, 99, 247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 12
    • 4544223707 scopus 로고    scopus 로고
    • Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking DNMT3L
    • Bourc'his, D.; Bestor, T.H. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking DNMT3L. Nature 2004, 431, 96-99.
    • (2004) Nature , vol.431 , pp. 96-99
    • Bourc'his, D.1    Bestor, T.H.2
  • 13
    • 3042584653 scopus 로고    scopus 로고
    • Essential role for de novo DNA methyltransferase DNMT3A in paternal and maternal imprinting
    • Kaneda, M.; Okano, M.; Hata, K.; Sado, T.; Tsujimoto, N.; Li, E.; Sasaki, H. Essential role for de novo DNA methyltransferase DNMT3A in paternal and maternal imprinting. Nature 2004, 429, 900-903.
    • (2004) Nature , vol.429 , pp. 900-903
    • Kaneda, M.1    Okano, M.2    Hata, K.3    Sado, T.4    Tsujimoto, N.5    Li, E.6    Sasaki, H.7
  • 14
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson, K.D. DNA methylation and human disease. Nat. Rev. Genet. 2005, 6, 597-610.
    • (2005) Nat. Rev. Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 15
    • 33646346610 scopus 로고    scopus 로고
    • Epigenetic deregulation of imprinting in congenital diseases of aberrant growth
    • Delaval, K.; Wagschal, A.; Feil, R. Epigenetic deregulation of imprinting in congenital diseases of aberrant growth. Bioessays 2006, 28, 453-459.
    • (2006) Bioessays , vol.28 , pp. 453-459
    • Delaval, K.1    Wagschal, A.2    Feil, R.3
  • 16
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg, A.P.; Tycko, B. The history of cancer epigenetics. Nat. Rev. Cancer 2004, 4, 143-153.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 18
    • 65449186589 scopus 로고    scopus 로고
    • A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation
    • El-Maarri, O.; Kareta, M.S.; Mikeska, T.; Becker, T.; Diaz-Lacava, A.; Junen, J.; Nusgen, N.; Behne, F.; Wienker, T.; Waha, A.; et al. A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation. Hum. Mol. Genet. 2009, 18, 1755-1768.
    • (2009) Hum. Mol. Genet , vol.18 , pp. 1755-1768
    • El-Maarri, O.1    Kareta, M.S.2    Mikeska, T.3    Becker, T.4    Diaz-Lacava, A.5    Junen, J.6    Nusgen, N.7    Behne, F.8    Wienker, T.9    Waha, A.10
  • 19
    • 0037383398 scopus 로고    scopus 로고
    • Endogenous assays of DNA methyltransferases: Evidence for differential activities of DNMT1, DNMT2, and DNMT3 in mammalian cells in vivo
    • Liu, K.; Wang, Y.F.; Cantemir, C.; Muller, M.T. Endogenous assays of DNA methyltransferases: Evidence for differential activities of DNMT1, DNMT2, and DNMT3 in mammalian cells in vivo. Mol. Cell Biol. 2003, 23, 2709-2719.
    • (2003) Mol. Cell Biol , vol.23 , pp. 2709-2719
    • Liu, K.1    Wang, Y.F.2    Cantemir, C.3    Muller, M.T.4
  • 20
    • 0032498296 scopus 로고    scopus 로고
    • DNA hypermethylation at the D17S5 locus is associated with gastric carcinogenesis
    • Kanai, Y.; Ushijima, S.; Ochiai, A.; Eguchi, K.; Hui, A.; Hirohashi, S. DNA hypermethylation at the D17S5 locus is associated with gastric carcinogenesis. Cancer Lett. 1998, 122, 135-141.
    • (1998) Cancer Lett , vol.122 , pp. 135-141
    • Kanai, Y.1    Ushijima, S.2    Ochiai, A.3    Eguchi, K.4    Hui, A.5    Hirohashi, S.6
  • 21
    • 77956645715 scopus 로고    scopus 로고
    • Lack of effects of single nucleotide polymorphisms of the DNA methyltransferase 1 gene on gastric cancer in Iranian patients: A case control study
    • Khatami, F.; Noorinayer, B.; Ghiasi, S.; Mohebi, R.; Hashemi, M.; Zali, M.R. Lack of effects of single nucleotide polymorphisms of the DNA methyltransferase 1 gene on gastric cancer in Iranian patients: A case control study. Asian Pac. J. Cancer Prev. 2009, 10, 1177-1182.
    • (2009) Asian Pac. J. Cancer Prev , vol.10 , pp. 1177-1182
    • Khatami, F.1    Noorinayer, B.2    Ghiasi, S.3    Mohebi, R.4    Hashemi, M.5    Zali, M.R.6
  • 22
    • 77649110590 scopus 로고    scopus 로고
    • A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma
    • Fan, H.; Liu, D.; Qiu, X.; Qiao, F.; Wu, Q.; Su, X.; Zhang, F.; Song, Y.; Zhao, Z.; Xie, W. A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma. BMC Med. 2010, 8, 12.
    • (2010) BMC Med , vol.8 , pp. 12
    • Fan, H.1    Liu, D.2    Qiu, X.3    Qiao, F.4    Wu, Q.5    Su, X.6    Zhang, F.7    Song, Y.8    Zhao, Z.9    Xie, W.10
  • 23
    • 77950347697 scopus 로고    scopus 로고
    • DNMT3B promoter polymorphism and risk of gastric cancer
    • Hu, J.; Fan, H.; Liu, D.; Zhang, S.; Zhang, F.; Xu, H. DNMT3B promoter polymorphism and risk of gastric cancer. Dig. Dis. Sci. 2010, 55, 1011-1016.
    • (2010) Dig. Dis. Sci , vol.55 , pp. 1011-1016
    • Hu, J.1    Fan, H.2    Liu, D.3    Zhang, S.4    Zhang, F.5    Xu, H.6
  • 24
    • 27744499023 scopus 로고    scopus 로고
    • No evidence of correlation between the single nucleotide polymorphism of DNMT3B promoter and gastric cancer risk in a Japanese population
    • Aung, P.P.; Matsumura, S.; Kuraoka, K.; Kunimitsu, K.; Yoshida, K.; Matsusaki, K.; Nakayama, H.; Yasui, W. No evidence of correlation between the single nucleotide polymorphism of DNMT3B promoter and gastric cancer risk in a Japanese population. Oncol. Rep. 2005, 14, 1151-1154.
    • (2005) Oncol. Rep , vol.14 , pp. 1151-1154
    • Aung, P.P.1    Matsumura, S.2    Kuraoka, K.3    Kunimitsu, K.4    Yoshida, K.5    Matsusaki, K.6    Nakayama, H.7    Yasui, W.8
  • 25
    • 84875573759 scopus 로고    scopus 로고
    • NCBI SNP Database. Available online, accessed on 13 October
    • NCBI SNP Database. Available online: http://www.ncbi.nlm.nih.gov/projects/SNP/(accessed on 13 October 2011).
    • (2011)
  • 26
    • 77957808708 scopus 로고    scopus 로고
    • Association of DNMT1 gene polymorphisms in exons with sporadic infiltrating ductal breast carcinoma among Chinese Han women in the Heilongjiang Province
    • Xiang, G.; Zhenkun, F.; Shuang, C.; Jie, Z.; Hua, Z.; Wei, J.; Da, P.; Dianjun, L. Association of DNMT1 gene polymorphisms in exons with sporadic infiltrating ductal breast carcinoma among Chinese Han women in the Heilongjiang Province. Clin. Breast Cancer 2010, 10, 373-377.
    • (2010) Clin. Breast Cancer , vol.10 , pp. 373-377
    • Xiang, G.1    Zhenkun, F.2    Shuang, C.3    Jie, Z.4    Hua, Z.5    Wei, J.6    Da, P.7    Dianjun, L.8
  • 30
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger, G.; Liang, G.; Aparicio, A.; Jones, P.A. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004, 429, 457-463.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 31
    • 13244265571 scopus 로고    scopus 로고
    • Target SNP selection in complex disease association studies
    • Wjst, M. Target SNP selection in complex disease association studies. BMC Bioinform. 2004, 5, 92.
    • (2004) BMC Bioinform , vol.5 , pp. 92
    • Wjst, M.1
  • 32
    • 9144256125 scopus 로고    scopus 로고
    • The DNMT1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
    • Hermann, A.; Goyal, R.; Jeltsch, A. The DNMT1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites. J. Biol. Chem. 2004, 279, 48350-48359.
    • (2004) J. Biol. Chem , vol.279 , pp. 48350-48359
    • Hermann, A.1    Goyal, R.2    Jeltsch, A.3
  • 33
    • 33847293264 scopus 로고    scopus 로고
    • Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
    • Chen, T.; Hevi, S.; Gay, F.; Tsujimoto, N.; He, T.; Zhang, B.; Ueda, Y.; Li, E. Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nat. Genet. 2007, 39, 391-396.
    • (2007) Nat. Genet , vol.39 , pp. 391-396
    • Chen, T.1    Hevi, S.2    Gay, F.3    Tsujimoto, N.4    He, T.5    Zhang, B.6    Ueda, Y.7    Li, E.8
  • 34
    • 80051544985 scopus 로고    scopus 로고
    • DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer
    • Mutze, K.; Langer, R.; Schumacher, F.; Becker, K.; Ott, K.; Novotny, A.; Hapfelmeier, A.; Hofler, H.; Keller, G. DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. Eur. J. Cancer 2011, 47, 1817-1825.
    • (2011) Eur. J. Cancer , vol.47 , pp. 1817-1825
    • Mutze, K.1    Langer, R.2    Schumacher, F.3    Becker, K.4    Ott, K.5    Novotny, A.6    Hapfelmeier, A.7    Hofler, H.8    Keller, G.9
  • 35
    • 80053097241 scopus 로고    scopus 로고
    • Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer
    • Yang, J.; Wei, X.; Wu, Q.; Xu, Z.; Gu, D.; Jin, Y.; Shen, Y.; Huang, H.; Fan, H.; Chen, J. Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer. Mol. Med. Rep. 2011, 4, 1139-1143.
    • (2011) Mol. Med. Rep , vol.4 , pp. 1139-1143
    • Yang, J.1    Wei, X.2    Wu, Q.3    Xu, Z.4    Gu, D.5    Jin, Y.6    Shen, Y.7    Huang, H.8    Fan, H.9    Chen, J.10
  • 36
    • 46449115224 scopus 로고    scopus 로고
    • The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer
    • Ding, W.J.; Fang, J.Y.; Chen, X.Y.; Peng, Y.S. The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer. Dig. Dis. Sci. 2008, 53, 2083-2089.
    • (2008) Dig. Dis. Sci , vol.53 , pp. 2083-2089
    • Ding, W.J.1    Fang, J.Y.2    Chen, X.Y.3    Peng, Y.S.4
  • 37
    • 1542319832 scopus 로고    scopus 로고
    • Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers
    • Etoh, T.; Kanai, Y.; Ushijima, S.; Nakagawa, T.; Nakanishi, Y.; Sasako, M.; Kitano, S.; Hirohashi, S. Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am. J. Pathol. 2004, 164, 689-699.
    • (2004) Am. J. Pathol , vol.164 , pp. 689-699
    • Etoh, T.1    Kanai, Y.2    Ushijima, S.3    Nakagawa, T.4    Nakanishi, Y.5    Sasako, M.6    Kitano, S.7    Hirohashi, S.8
  • 39
    • 0041355334 scopus 로고    scopus 로고
    • The human DNMT2 has residual DNA-(cytosine-C5) methyltransferase activity
    • Hermann, A.; Schmitt, S.; Jeltsch, A. The human DNMT2 has residual DNA-(cytosine-C5) methyltransferase activity. J. Biol. Chem. 2003, 278, 31717-31721.
    • (2003) J. Biol. Chem , vol.278 , pp. 31717-31721
    • Hermann, A.1    Schmitt, S.2    Jeltsch, A.3
  • 40
    • 1442310498 scopus 로고    scopus 로고
    • Focus on gastric cancer
    • Ushijima, T.; Sasako, M. Focus on gastric cancer. Cancer Cell 2004, 5, 121-125.
    • (2004) Cancer Cell , vol.5 , pp. 121-125
    • Ushijima, T.1    Sasako, M.2
  • 43
    • 21344442404 scopus 로고    scopus 로고
    • Single nucleotide polymorphism in DNA methyltransferase 3B promoter and its association with gastric cardiac adenocarcinoma in North China
    • Wang, Y.M.; Wang, R.; Wen, D.G.; Li, Y.; Guo, W.; Wang, N.; Wei, L.Z.; He, Y.T.; Chen, Z.F.; Zhang, X.F. et al. Single nucleotide polymorphism in DNA methyltransferase 3B promoter and its association with gastric cardiac adenocarcinoma in North China. World J. Gastroenterol. 2005, 11, 3623-3627.
    • (2005) World J. Gastroenterol , vol.11 , pp. 3623-3627
    • Wang, Y.M.1    Wang, R.2    Wen, D.G.3    Li, Y.4    Guo, W.5    Wang, N.6    Wei, L.Z.7    He, Y.T.8    Chen, Z.F.9    Zhang, X.F.10
  • 44
    • 49249097250 scopus 로고    scopus 로고
    • DNMT3B 579 G>T promoter polymorphism and risk of esophagus carcinoma in Chinese
    • Fan, H.; Liu, D.S.; Zhang, S.H.; Hu, J.B.; Zhang, F.; Zhao, Z.J. DNMT3B 579 G>T promoter polymorphism and risk of esophagus carcinoma in Chinese. World J. Gastroenterol. 2008, 14, 2230-2234.
    • (2008) World J. Gastroenterol , vol.14 , pp. 2230-2234
    • Fan, H.1    Liu, D.S.2    Zhang, S.H.3    Hu, J.B.4    Zhang, F.5    Zhao, Z.J.6
  • 45
    • 7044254997 scopus 로고    scopus 로고
    • The DNMT3B C→T promoter polymorphism and risk of breast cancer in a British population: A case-control study
    • Montgomery, K.G.; Liu, M.C.; Eccles, D.M.; Campbell, I.G. The DNMT3B C→T promoter polymorphism and risk of breast cancer in a British population: A case-control study. Breast Cancer Res. 2004, 6, R390-R394.
    • (2004) Breast Cancer Res , vol.6
    • Montgomery, K.G.1    Liu, M.C.2    Eccles, D.M.3    Campbell, I.G.4
  • 47
    • 0037168587 scopus 로고    scopus 로고
    • The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by DNMT3A
    • Chedin, F.; Lieber, M.R.; Hsieh, C.L. The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by DNMT3A. Proc. Natl. Acad. Sci. USA 2002, 99, 16916-16921.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 16916-16921
    • Chedin, F.1    Lieber, M.R.2    Hsieh, C.L.3
  • 48
    • 33748740832 scopus 로고    scopus 로고
    • Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L
    • Kareta, M.S.; Botello, Z.M.; Ennis, J.J.; Chou, C.; Chedin, F. Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L. J. Biol. Chem. 2006, 281, 25893-25902.
    • (2006) J. Biol. Chem , vol.281 , pp. 25893-25902
    • Kareta, M.S.1    Botello, Z.M.2    Ennis, J.J.3    Chou, C.4    Chedin, F.5
  • 49
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones, P.A.; Baylin, S.B. The epigenomics of cancer. Cell 2007, 128, 683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 50
    • 69949107733 scopus 로고    scopus 로고
    • Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis
    • Gokul, G.; Ramakrishna, G.; Khosla, S. Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis. Epigenetics 2009, 4, 322-329.
    • (2009) Epigenetics , vol.4 , pp. 322-329
    • Gokul, G.1    Ramakrishna, G.2    Khosla, S.3
  • 51
    • 77956224313 scopus 로고    scopus 로고
    • Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking
    • Haggarty, P.; Hoad, G.; Harris, S.E.; Starr, J.M.; Fox, H.C.; Deary, I.J.; Whalley, L.J. Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking. PLoS One 2010, 5, e11329.
    • (2010) PLoS One , vol.5
    • Haggarty, P.1    Hoad, G.2    Harris, S.E.3    Starr, J.M.4    Fox, H.C.5    Deary, I.J.6    Whalley, L.J.7
  • 52
    • 84875556754 scopus 로고    scopus 로고
    • International HapMap Project Database. Available online, accessed on 13 June
    • International HapMap Project Database. Available online: http://hapmap.ncbi.nlm.nih.gov/ (accessed on 13 June 2011).
    • (2011)
  • 53
    • 33747827929 scopus 로고    scopus 로고
    • SNPStats: A web tool for the analysis of association studies
    • Solé, X.; Guinó, E.; Valls, J.; Iniesta, R.; Moreno, V. SNPStats: A web tool for the analysis of association studies. Bioinformatics 2006, 22, 1928-1929.
    • (2006) Bioinformatics , vol.22 , pp. 1928-1929
    • Solé, X.1    Guinó, E.2    Valls, J.3    Iniesta, R.4    Moreno, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.