Palmitate enhances the differentiation of mouse embryonic stem cells towards white adipocyte lineages

Molecular and Cellular Endocrinology

Volumn 361, Issue 1-2, 2012, Pages 40-50

  Petrighi Polidori, Gioia ^a   Lomax, Michael A ^a,b   Docherty, Kevin ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Adipocytes; Obesity; Palmitate; Sex steroid hormones; Subcutaneous fat

Indexed keywords

ADIPONECTIN; BONE MORPHOGENETIC PROTEIN 4; CATECHOLAMINE; CELL MARKER; ENZYME; IGFBP2 PROTEIN; IGFBP3 PROTEIN; PALMITIC ACID; RETINOIC ACID; SHOX2 PROTEIN; TWIST1 PROTEIN; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; INTRAABDOMINAL FAT; LIPID STORAGE; LIPOLYSIS; MOUSE; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; SUBCUTANEOUS FAT; WHITE ADIPOSE TISSUE;

ADIPOCYTES, WHITE; ANIMALS; BIOLOGICAL MARKERS; BONE MORPHOGENETIC PROTEIN 4; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; DEHYDROEPIANDROSTERONE; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; GONADAL STEROID HORMONES; METHYLAMINES; MICE; PALMITATES; PPAR GAMMA; PROPIONATES; TIME FACTORS; TRETINOIN;

EID: 84864347883     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.03.010     Document Type: Article

References (53)

1. Amri E.Z., Ailhaud G., Grimaldi P.A. Fatty acids as signal transducing molecules: involvement in the differentiation of preadipose to adipose cells. J. Lipid Res. 1994, 35:930-937.
2. Arenz S., Ruckerl R., Koletzko B., von Kries R. Breast-feeding and childhood obesity-a systematic review. Int. J. Obes. Relat. Metab. Disord. 2004, 28:1247-1256.
3. Bain G., Kitchens D., Yao M., Huettner J.E., Gottlieb D.I. Embryonic stem cells express neuronal properties in vitro. Dev. Biol. 1995, 168:342-357.
4. Bayol S.A., Simbi B.H., Bertrand J.A., Stickland N.C. Offspring from mothers fed a 'junk food' diet in pregnancy and lactation exhibit exacerbated adiposity that is more pronounced in females. J. Physiol. 2008, 586:3219-3230.
5. Belanger C., Hould F.S., Lebel S., Biron S., Brochu G., Tchernof A. Omental and subcutaneous adipose tissue steroid levels in obese men. Steroids 2006, 71:674-682.
6. Bernardo A.S., Cho C.H., Mason S., Docherty H.M., Pedersen R.A., Vallier L., Docherty K. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Stem cells 2009, 27:341-351.
7. Bernardo A.S., Faial T., Gardner L., Niakan K.K., Ortmann D., Senner C.E., Callery E.M., Trotter M.W., Hemberger M., Smith J.C., et al. BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell 2011, 9:144-155.
8. Bibel M., Richter J., Schrenk K., Tucker K.L., Staiger V., Korte M., Goetz M., Barde Y. Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nat. Neurosci. 2004, 7:1003-11009.
9. Billon N., Iannarelli P., Monteiro M.C., Glavieux-Pardanaud C., Richardson W.D., Kessaris N., Dani C., Dupin E. The generation of adipocytes by the neural crest. Development 2007, 134:2283-2292.
10. Blouin K., Nadeau M., Mailloux J., Daris M., Lebel S., Luu-The V., Tchernof A. Pathways of adipose tissue androgen metabolism in women: depot differences and modulation by adipogenesis. Am. J. Physiol. Endocrinol. Metab. 2009, 296:E244-55.
11. Blouin K., Veilleux A., Luu-The V., Tchernof A. Androgen metabolism in adipose tissue: recent advances. Mol. Cell. Endocrinol. 2009, 301:97-103.
12. Bost F., Caron L., Marchetti I., Dani C., Marchand-Brustel Y., Binetruy B. Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage. Biochem. J. 2002, 361:621-627.
13. Bowers R.R., Kim J.W., Otto T.C., Lane M.D. Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene. Proc. Natl. Acad. Sci. USA 2006, 103:13022-13027.
14. Cherubino M., Marra K.G. Adipose-derived stem cells for soft tissue reconstruction. Regen. Med. 2009, 4:109-117.
15. Cherubino M., Rubin J.P., Miljkovic N., Kelmendi-Doko A., Marra K.G. Adipose-derived stem cells for wound healing applications. Ann. Plast. Surg. 2011, 66:210-215.
16. Chiang P., Wong P.C. Differentiation of embryonic stem cells to hemogenic endothelium by defined factors: essential role of bone morphogenetic protein 4. Development 2011, 138:2833-2843.
17. Cianflone K., Maslowska M., Sniderman A.D. Acylation stimulating protein (ASP), an adipocyte autocrine: new directions. Semin. Cell Dev. Biol. 1999, 10:31-41.
18. Dani C., Smith A.G., Dessolin S., Leroy P., Staccini L., Villageois P., Darimont C., Ailhaud G. Differentiation of embryonic stem cells into adipocytes in vitro. J. Cell. Sci. 1997, 110:1279-1285.
19. Funder J.W., Pearce P.T., Smith R., Smith A.I. Minealrcorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 1998, 242:583-585.
20. Gentile C.L., Wang D., Pfaffenbach K.T., Cox R., Wei Y., Pagliassotti M.J. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. Mol. Cell. Biochem. 2010, 344:99-107.
21. Gesta S., Tseng Y.H., Kahn C.R. Developmental origin of fat: Tracking obesity to its source. Cell 2007, 131:242-256.
22. Gnanalingham M.G., Mostyn A., Symonds M.E., Stephenson T. Ontogeny and nutritional programming of adiposity in sheep: potential role of glucocorticoid action and uncoupling protein-2. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 289:R1407-15.
23. Gotoh C., Hong Y.H., Iga T., Hishikawa D., Suzuki Y., Song S.H., Choi K.C., Adachi T., Hirasawa A., Tsujimoto G., et al. The regulation of adipogenesis through GPR120. Biochem. Biophys. Res. Commun. 2007, 354:591-597.
24. Hamilton B.S., Paglia D., Kwan A.Y., Deitel M. Increased obese mRNA expression in omental fat cells from massively obese humans. Nat. Med. 1995, 1:953-956.
25. Hwang N.S., Varghese S., Lee H.J., Zhang Z., Ye Z., Bae J., Cheng L., Elisseeff J. In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. Proc. Natl. Acad. Sci. USA 2008, 103:13022-13027.
26. Johansson B.M., Wiles M.V. Evidence for involvement of activin A and Bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development. Mol. Cell. Endocrinol. 1995, 15:141-151.
27. Kotasová H., Veselá I., Kučera J., Houdek Z., Procházkovrá J., Králičkovrá M., Pacherník J. Phosphoinositide 3-kinase inhibition enables retinoicacid-induced neurogenesis in monolayer culture of embryonic stem cells. J. Cell. Biochem. 2012, 113:563-570.
28. Labrie F., Luu-The V., Labrie C., Belanger A., Simard J., Lin S.X., Pelletier G. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr. Rev. 2003, 24:152-182.
29. Lefebvre A.M., Laville M., Vega N., Riou J.P., van Gaal L., Auwerx J., Vidal H. Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes 1998, 47:98-103.
30. Lewis D.S., Bertrand H.A., McMahan C.A., McGill H.C., Carey K.D., Masoro E.J. Preweaning food intake influences the adiposity of young adult baboons. J. Clin. Invest. 1986, 78:899-905.
31. Linder K., Arner P., Flores-Morales A., Tollet-Egnell P., Norstedt G. Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women. J. Lipid Res. 2004, 45:148-154.
32. McCance R.A. Food, growth, and time. Lancet 1962, 2:671-676.
33. Montague C.T., Prins J.B., Sanders L., Zhang J., Sewter C.P., Digby J., Byrne C.D., O'Rahilly S. Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes 1998, 47:1384-1391.
34. Nichols J., Evans E.P., Smith A.G. Establishemnt of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity. Development 1990, 110:1341-1348.
35. Ong K.K., Loos R.J. Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions. Acta Paediatr. 2006, 95:904-908.
36. Qiao L., Zou C., Shao P., Schaack J., Johnson P.F., Shao J. Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha. J. Biol. Chem. 2008, 283:8788-8795.
37. Rodeheffer M.S., Birsoy K., Friedman J.M. Identification of white adipocyte progenitor cells in vivo. Cell 2008, 135:240-249.
38. Rosen E.D. The transcriptional basis of adipocyte development. Prostaglandins Leukot. Essent. Fatty Acids 2005, 73:31-34.
39. Spalding K.L., Arner E., Westermark P.O., Bernard S., Buchholz B.A., Bergmann O., Blomqvist L., Hoffstedt J., Naslund E., Britton T., et al. Dynamics of fat cell turnover in humans. Nature 2008, 453:783-787.
40. Takashima Y., Era T., Nakao K., Kondo S., Kasuga M., Smith A.G., Nishikawa S. Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell 2007, 129:1377-1388.
41. Tang W., Zeve D., Suh J.M., Bosnakovski D., Kyba M., Hammer R.E., Tallquist M.D., Graff J.M. White fat progenitor cells reside in the adipose vasculature. Science 2008, 322:583-586.
42. Tchkonia T., Lenburg M., Thomou T., Giorgadze N., Frampton G., Pirtskhalava T., Cartwright A., Cartwright M., Flanagan J., Karagiannides I., et al. Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns. Am. J. Physiol. Endocrinol. Metab. 2007, 292:E298-307.
43. Tchoukalova Y.D., Votruba S.B., Tchkonia T., Giorgadze N., Kirkland J.L., Jensen M.D. Regional differences in cellular mechanisms of adipose tissue gain with overfeeding. Proc. Natl. Acad. Sci. USA 2010, 107:18226-18231.
44. Thuillier P., Baillie R., Sha X., Clarke S.D. Cytosolic and nuclear distribution of PPARgamma2 in differentiating 3T3-L1 preadipocytes. J. Lipid Res. 1998, 39:2329-2338.
45. van Beek E.A., Bakker A.H., Kruyt P.M., Hofker M.H., Saris W.H., Keijer J. Intra- and interindividual variation in gene expression in human adipose tissue. Pflugers Arch. 2007, 453:851-861.
46. Vernochet C., Milstone D.S., Iehle C., Belmonte N., Phillips B., Wdziekonski B., Villageois P., Amri E.Z., O'Donnell P.E., Mortensen R.M., et al. PPARgamma-dependent and PPARgamma-independent effects on the development of adipose cells from embryonic stem cells. FEBS Lett. 2002, 510:94-98.
47. Vohl M.C., Sladek R., Robitaille J., Gurd S., Marceau P., Richard D., Hudson T.J., Tchernof A. A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men. Obes. Res. 2004, 12:1217-1222.
48. Wake D.J., Rask E., Livingstone D.E., Soderberg S., Olsson T., Walker B.R. Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity. J. Clin. Endocrinol. Metab. 2003, 88:3983-3988.
49. Weigert C., Brodbeck K., Staiger H., Kausch C., Machicao F., Haring H.U., Schleicher E.D. Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB. J. Biol. Chem. 2004, 279:23942-23952.
50. Winnier G., Blessing M., Labosky P.A., Hogan B.L. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 1995, 9:2105-2116.
51. 2+ channels. In Vitro Cell. Dev. Biol. Anim. 1994, 30A:425-434.
52. Xie W., Hamilton J.A., Kirkland J.L., Corkey B.E., Guo W. Oleate-induced formation of fat cells with impaired insulin sensitivity. Lipids 2006, 41:267-271.
53. Yang J.Y., Della-Fera M.A., Rayalam S., Park H.J., Ambati S., Hausman D.B., Hartzell D.L., Baile C.A. Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail. J. Nutr. Biochem. 2009, 20:537-543.