메뉴 건너뛰기




Volumn 138, Issue 7, 2012, Pages 1145-1154

Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells

Author keywords

A375 melanoma cell line; Amoeboid movement; Mesenchymal movement; Nanog; Oct4

Indexed keywords

EPHRIN RECEPTOR A2; FOCAL ADHESION KINASE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN CDC42; RAC PROTEIN; TALIN; TRANSCRIPTION FACTOR NANOG;

EID: 84864338902     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1186-2     Document Type: Article
Times cited : (49)

References (38)
  • 2
    • 67650491811 scopus 로고    scopus 로고
    • Treatment of metastatic melanoma: An overview
    • (Williston Park)
    • Bhatia S, Tykodi SS, Thompson JA (2009) Treatment of metastatic melanoma: an overview. Oncology (Williston Park) 23(6): 488-496
    • (2009) Oncology , vol.23 , Issue.6 , pp. 488-496
    • Bhatia, S.1    Tykodi, S.S.2    Thompson, J.A.3
  • 3
    • 50949166635 scopus 로고    scopus 로고
    • Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells
    • doi:10.1158/ 0008-5472.CAN-08-0094
    • Chang CC, Shieh GS, Wu P, Lin CC, Shiau AL, Wu CL (2008) Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells. Cancer Res 68(15):6281-6291. doi:10.1158/ 0008-5472.CAN-08-0094
    • (2008) Cancer Res , vol.68 , Issue.15 , pp. 6281-6291
    • Chang, C.C.1    Shieh, G.S.2    Wu, P.3    Lin, C.C.4    Shiau, A.L.5    Wu, C.L.6
  • 4
    • 79956131573 scopus 로고    scopus 로고
    • Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny
    • doi:10.1038/onc.2010.598
    • Cheli Y, Giuliano S, Botton T, Rocchi S, Hofman V, Hofman P, Bahadoran P, Bertolotto C, Ballotti R (2011) Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny. Oncogene 30(20):2307-2318. doi:10.1038/onc.2010.598
    • (2011) Oncogene , vol.30 , Issue.20 , pp. 2307-2318
    • Cheli, Y.1    Giuliano, S.2    Botton, T.3    Rocchi, S.4    Hofman, V.5    Hofman, P.6    Bahadoran, P.7    Bertolotto, C.8    Ballotti, R.9
  • 5
    • 78650389774 scopus 로고    scopus 로고
    • Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
    • doi:10.1158/0008-5472.CAN-10-2638
    • Chiou SH, Wang ML, Chou YT, Chen CJ, Hong CF, Hsieh WJ, Chang HT, Chen YS, Lin TW, Hsu HS, Wu CW (2010) Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res 70(24):10433-10444. doi:10.1158/0008-5472.CAN-10-2638
    • (2010) Cancer Res , vol.70 , Issue.24 , pp. 10433-10444
    • Chiou, S.H.1    Wang, M.L.2    Chou, Y.T.3    Chen, C.J.4    Hong, C.F.5    Hsieh, W.J.6    Chang, H.T.7    Chen, Y.S.8    Lin, T.W.9    Hsu, H.S.10    Wu, C.W.11
  • 7
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • DOI 10.1038/35020106
    • Clark EA, Golub TR, Lander ES, Hynes RO (2000) Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406(6795):532-535. doi:10.1038/35020106 (Pubitemid 30625739)
    • (2000) Nature , vol.406 , Issue.6795 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 8
    • 66249129372 scopus 로고    scopus 로고
    • Oct4 is expressed in human gliomas and promotes colony formation in glioma cells
    • doi:10.1002/ glia.20800
    • Du Z, Jia D, Liu S, Wang F, Li G, Zhang Y, Cao X, Ling EA, Hao A (2009) Oct4 is expressed in human gliomas and promotes colony formation in glioma cells. Glia 57(7):724-733. doi:10.1002/ glia.20800
    • (2009) Glia , vol.57 , Issue.7 , pp. 724-733
    • Du, Z.1    Jia, D.2    Liu, S.3    Wang, F.4    Li, G.5    Zhang, Y.6    Cao, X.7    Ling, E.A.8    Hao, A.9
  • 9
    • 33645474441 scopus 로고    scopus 로고
    • Gene expression in poorly differentiated papillary thyroid carcinomas
    • Fluge O, Bruland O, Akslen LA, Lillehaug JR, Varhaug JE (2006) Gene expression in poorly differentiated papillary thyroid carcinomas. Thyroid 16(2):161-175
    • (2006) Thyroid , vol.16 , Issue.2 , pp. 161-175
    • Fluge, O.1    Bruland, O.2    Akslen, L.A.3    Lillehaug, J.R.4    Varhaug, J.E.5
  • 10
    • 53249143863 scopus 로고    scopus 로고
    • DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells
    • doi: 10.1016/j.cub.2008.08.053
    • Gadea G, Sanz-Moreno V, Self A, Godi A, Marshall CJ (2008) DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells. Curr Biol 18(19):1456-1465. doi: 10.1016/j.cub.2008.08.053
    • (2008) Curr Biol , vol.18 , Issue.19 , pp. 1456-1465
    • Gadea, G.1    Sanz-Moreno, V.2    Self, A.3    Godi, A.4    Marshall, C.J.5
  • 11
    • 79956008208 scopus 로고    scopus 로고
    • Junctional adhesion molecules are required for melanoma cell lines transendothelial migration in vitro
    • doi:10.1111/j. 1755-148X.2011.00856.x
    • Ghislin S, Obino D, Middendorp S, Boggetto N, Alcaide-Loridan C, Deshayes F (2011) Junctional adhesion molecules are required for melanoma cell lines transendothelial migration in vitro. Pigment Cell Melanoma Res 24(3):504-511. doi:10.1111/j. 1755-148X.2011.00856.x
    • (2011) Pigment Cell Melanoma Res , vol.24 , Issue.3 , pp. 504-511
    • Ghislin, S.1    Obino, D.2    Middendorp, S.3    Boggetto, N.4    Alcaide-Loridan, C.5    Deshayes, F.6
  • 13
    • 21644487903 scopus 로고    scopus 로고
    • Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study
    • DOI 10.1002/jcp.20320
    • Ghosh S, Spagnoli GC, Martin I, Ploegert S, Demougin P, Heberer M, Reschner A (2005) Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study. J Cell Physiol 204(2):522-531. doi: 10.1002/jcp.20320 (Pubitemid 40934647)
    • (2005) Journal of Cellular Physiology , vol.204 , Issue.2 , pp. 522-531
    • Ghosh, S.1    Spagnoli, G.C.2    Martin, I.3    Ploegert, S.4    Demougin, P.5    Heberer, M.6    Reschner, A.7
  • 16
    • 38849203228 scopus 로고    scopus 로고
    • In vivo switching of human melanoma cells between proliferative and invasive states
    • DOI 10.1158/0008-5472.CAN-07-2491
    • Hoek KS, Eichhoff OM, Schlegel NC, Dobbeling U, Kobert N, Schaerer L, Hemmi S, Dummer R (2008) In vivo switching of human melanoma cells between proliferative and invasive states. Cancer Res 68(3):650-656. doi:10.1158/0008-5472.CAN-07-2491 (Pubitemid 351206739)
    • (2008) Cancer Research , vol.68 , Issue.3 , pp. 650-656
    • Hoek, K.S.1    Eichhoff, O.M.2    Schlegel, N.C.3    Dobbeling, U.4    Kobert, N.5    Schaerer, L.6    Hemmi, S.7    Dummer, R.8
  • 18
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • doi:10.3322/caac.20073
    • Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics, 2010. CA Cancer J Clin 60(5):277-300. doi:10.3322/caac.20073
    • (2010) CA Cancer J Clin , vol.60 , Issue.5 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3    Ward, E.4
  • 20
    • 67650810301 scopus 로고    scopus 로고
    • Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the Nanog, Oct4, and Sox2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs
    • doi:10.1089/scd.2009.0113
    • Kashyap V, Rezende NC, Scotland KB, Shaffer SM, Persson JL, Gudas LJ, Mongan NP (2009) Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the Nanog, Oct4, and Sox2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev 18(7):1093-1108. doi:10.1089/scd.2009.0113
    • (2009) Stem Cells Dev , vol.18 , Issue.7 , pp. 1093-1108
    • Kashyap, V.1    Rezende, N.C.2    Scotland, K.B.3    Shaffer, S.M.4    Persson, J.L.5    Gudas, L.J.6    Mongan, N.P.7
  • 21
    • 0037217912 scopus 로고    scopus 로고
    • Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer
    • DOI 10.1023/A:1022546620495
    • Kinch MS, Carles-Kinch K (2003) Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer. Clin Exp Metastasis 20(1):59-68 (Pubitemid 36308137)
    • (2003) Clinical and Experimental Metastasis , vol.20 , Issue.1 , pp. 59-68
    • Kinch, M.S.1    Carles-Kinch, K.2
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25(4):402-408. doi:10.1006/meth. 2001.1262 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 70349900618 scopus 로고    scopus 로고
    • Coexpression of major histocompatibility complex class II with chemokines and nuclear NFkappaB p50 in melanoma: A rational for their association with poor prognosis
    • doi:10.1097/CMR.0b013 e32832e0bc3
    • Martins I, Sylla K, Deshayes F, Lauriol J, Ghislin S, Dieu-Nosjean MC, Viguier M, Verola O, Charron D, Alcaide-Loridan C, Al- Daccak R (2009) Coexpression of major histocompatibility complex class II with chemokines and nuclear NFkappaB p50 in melanoma: a rational for their association with poor prognosis. Melanoma Res 19(4):226-237. doi:10.1097/CMR.0b013 e32832e0bc3
    • (2009) Melanoma Res , vol.19 , Issue.4 , pp. 226-237
    • Martins, I.1    Sylla, K.2    Deshayes, F.3    Lauriol, J.4    Ghislin, S.5    Dieu-Nosjean, M.C.6    Viguier, M.7    Verola, O.8    Charron, D.9    Alcaide-Loridan, C.10    Al- Daccak, R.11
  • 24
    • 73749086570 scopus 로고    scopus 로고
    • The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells
    • doi: 10.1007/s00018-009-0132-1
    • Pankova K, Rosel D, Novotny M, Brabek J (2010) The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells. Cell Mol Life Sci 67(1):63-71. doi: 10.1007/s00018-009-0132-1
    • (2010) Cell Mol Life Sci , vol.67 , Issue.1 , pp. 63-71
    • Pankova, K.1    Rosel, D.2    Novotny, M.3    Brabek, J.4
  • 25
    • 62449186707 scopus 로고    scopus 로고
    • EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style
    • doi:10.1158/0008-5472.CAN-08-1845
    • Parri M, Taddei ML, Bianchini F, Calorini L, Chiarugi P (2009) EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style. Cancer Res 69(5):2072-2081. doi:10.1158/0008-5472. CAN-08- 1845
    • (2009) Cancer Res , vol.69 , Issue.5 , pp. 2072-2081
    • Parri, M.1    Taddei, M.L.2    Bianchini, F.3    Calorini, L.4    Chiarugi, P.5
  • 27
    • 38849185196 scopus 로고    scopus 로고
    • PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
    • DOI 10.1038/ncb1675, PII NCB1675
    • Pinner S, Sahai E (2008) PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nat Cell Biol 10(2):127-137. doi:10.1038/ncb1675 (Pubitemid 351194042)
    • (2008) Nature Cell Biology , vol.10 , Issue.2 , pp. 127-137
    • Pinner, S.1    Sahai, E.2
  • 28
  • 29
    • 33846014269 scopus 로고    scopus 로고
    • Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility
    • DOI 10.1083/jcb.200605135
    • Sahai E, Garcia-Medina R, Pouyssegur J, Vial E (2007) Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility. J Cell Biol 176(1):35-42. doi:10.1083/jcb.200605135 (Pubitemid 46041678)
    • (2007) Journal of Cell Biology , vol.176 , Issue.1 , pp. 35-42
    • Sahai, E.1    Garcia-Medina, R.2    Pouyssegur, J.3    Vial, E.4
  • 30
    • 77950203804 scopus 로고    scopus 로고
    • Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance
    • doi:10.1158/0008-5472.CAN-09-2833
    • Sakamoto S, McCann RO, Dhir R, Kyprianou N (2010) Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance. Cancer Res 70(5):1885-1895. doi:10.1158/0008-5472.CAN-09-2833
    • (2010) Cancer Res , vol.70 , Issue.5 , pp. 1885-1895
    • Sakamoto, S.1    McCann, R.O.2    Dhir, R.3    Kyprianou, N.4
  • 31
    • 54549088877 scopus 로고    scopus 로고
    • Rac activation and inactivation control plasticity of tumor cell movement
    • doi:10.1016/j.cell.2008.09.043
    • Sanz-Moreno V, Gadea G, Ahn J, Paterson H, Marra P, Pinner S, Sahai E, Marshall CJ (2008) Rac activation and inactivation control plasticity of tumor cell movement. Cell 135(3):510-523. doi:10.1016/j.cell.2008.09.043
    • (2008) Cell , vol.135 , Issue.3 , pp. 510-523
    • Sanz-Moreno, V.1    Gadea, G.2    Ahn, J.3    Paterson, H.4    Marra, P.5    Pinner, S.6    Sahai, E.7    Marshall, C.J.8
  • 32
    • 53149084888 scopus 로고    scopus 로고
    • Overexpression of NANOG in gestational trophoblastic diseases: Effect on apoptosis, cell invasion, and clinical outcome
    • doi:10.2353/ajpath.2008.080288
    • Siu MK, Wong ES, Chan HY, Ngan HY, Chan KY, Cheung AN (2008) Overexpression of NANOG in gestational trophoblastic diseases: effect on apoptosis, cell invasion, and clinical outcome. Am J Pathol 173(4):1165-1172. doi:10.2353/ajpath.2008.080288
    • (2008) Am J Pathol , vol.173 , Issue.4 , pp. 1165-1172
    • Siu, M.K.1    Wong, E.S.2    Chan, H.Y.3    Ngan, H.Y.4    Chan, K.Y.5    Cheung, A.N.6
  • 33
    • 77749291745 scopus 로고    scopus 로고
    • Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells
    • doi:10.2353/ ajpath.2010.090188
    • Tan TK, Zheng G, Hsu TT, Wang Y, Lee VW, Tian X, Cao Q, Harris DC (2010) Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells. Am J Pathol 176(3):1256-1270. doi:10.2353/ ajpath.2010.090188
    • (2010) Am J Pathol , vol.176 , Issue.3 , pp. 1256-1270
    • Tan, T.K.1    Zheng, G.2    Hsu, T.T.3    Wang, Y.4    Lee, V.W.5    Tian, X.6    Cao, Q.7    Harris, D.C.8
  • 34
    • 27844496091 scopus 로고    scopus 로고
    • Regulation of paxillin family members during epithelial-mesenchymal transformation: A putative role for paxillin δ
    • DOI 10.1242/jcs.02615
    • Tumbarello DA, Brown MC, Hetey SE, Turner CE (2005) Regulation of paxillin family members during epithelial-mesenchymal transformation: a putative role for paxillin delta. J Cell Sci 118(Pt 20):4849-4863. doi:10.1242/jcs.02615 (Pubitemid 41646392)
    • (2005) Journal of Cell Science , vol.118 , Issue.20 , pp. 4849-4863
    • Tumbarello, D.A.1    Brown, M.C.2    Hetey, S.E.3    Turner, C.E.4
  • 35
    • 0344758986 scopus 로고    scopus 로고
    • Regulation of cell polarity and protrusion formation by targeting rhoa for degradation
    • DOI 10.1126/science.1090772
    • Wang HR, Zhang Y, Ozdamar B, Ogunjimi AA, Alexandrova E, Thomsen GH, Wrana JL (2003) Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302(5651):1775-1779. doi:10.1126/science.1090772 (Pubitemid 37505743)
    • (2003) Science , vol.302 , Issue.5651 , pp. 1775-1779
    • Wang, H.-R.1    Zhang, Y.2    Ozdamar, B.3    Ogunjimi, A.A.4    Alexandrova, E.5    Thomsen, G.H.6    Wrana, J.L.7
  • 36
    • 77954117118 scopus 로고    scopus 로고
    • Oct4 and Nanog expression is associated with early stages of pancreatic carcinogenesis
    • doi:10.1097/MPA.0b013e3181c75f5e
    • Wen J, Park JY, Park KH, Chung HW, Bang S, Park SW, Song SY (2010) Oct4 and Nanog expression is associated with early stages of pancreatic carcinogenesis. Pancreas 39(5):622-626. doi:10.1097/MPA.0b013e3181c75f5e
    • (2010) Pancreas , vol.39 , Issue.5 , pp. 622-626
    • Wen, J.1    Park, J.Y.2    Park, K.H.3    Chung, H.W.4    Bang, S.5    Park, S.W.6    Song, S.Y.7
  • 37
    • 0037455576 scopus 로고    scopus 로고
    • Compensation mechanism in tumor cell migration: Mesenchymal-amoeboid transition after blocking of pericellular proteolysis
    • DOI 10.1083/jcb.200209006
    • Wolf K, Mazo I, Leung H, Engelke K, von Andrian UH, Deryugina EI, Strongin AY, Brocker EB, Friedl P (2003) Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol 160(2):267-277. doi:10.1083/jcb.200209006 (Pubitemid 36254960)
    • (2003) Journal of Cell Biology , vol.160 , Issue.2 , pp. 267-277
    • Wolf, K.1    Mazo, I.2    Leung, H.3    Engelke, K.4    Von Andrian, U.H.5    Deryugina, E.I.6    Strongin, A.Y.7    Brocker, E.-B.8    Friedl, P.9
  • 38
    • 77952902430 scopus 로고    scopus 로고
    • Mechanisms of motility in metastasizing cells
    • doi:10.1158/1541-7786. MCR-10-0139
    • Yilmaz M, Christofori G (2010) Mechanisms of motility in metastasizing cells. Mol Cancer Res 8(5):629-642. doi:10.1158/1541-7786. MCR-10-0139
    • (2010) Mol Cancer Res , vol.8 , Issue.5 , pp. 629-642
    • Yilmaz, M.1    Christofori, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.