Phosphorylation of elongation factor-2 kinase differentially regulates the enzyme's stability under stress conditions

Biochemical and Biophysical Research Communications

Volumn 424, Issue 2, 2012, Pages 308-314

  Huber Keener, Kathryn J ^a   Evans, Brad R ^a   Ren, Xingcong ^a   Cheng, Yan ^a   Zhang, Yi ^a   Hait, William N ^a   Yang, Jin Ming ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

AMPK; EEF 2K; Enzyme stability; Glioblastoma; Phosphorylation; Protein synthesis

Indexed keywords

ELONGATION FACTOR 2 KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CELL HYPOXIA; CELL STRESS; CELL SURVIVAL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME STABILITY; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN STABILITY; PROTEIN SYNTHESIS; REGULATORY MECHANISM;

CELL LINE, TUMOR; ELONGATION FACTOR 2 KINASE; ENZYME STABILITY; HUMANS; MUTATION; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIROLIMUS; STRESS, PHYSIOLOGICAL; TOR SERINE-THREONINE KINASES;

EUKARYOTA;

EID: 84864323305     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.06.112     Document Type: Article

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