Advancing pig cloning technologies towards application in regenerative medicine

Reproduction in Domestic Animals

Volumn 47, Issue SUPPL.4, 2012, Pages 120-126

  Nagashima, H ^a   Matsunari, H ^a   Nakano, K ^a   Watanabe, M ^a   Umeyama, K ^a   Nagaya, M ^a  

^a MEIJI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; CLONING; GENETICS; KIDNEY; METHODOLOGY; PANCREAS; PHYSIOLOGY; REGENERATION; SWINE;

ANIMALS; CLONING, ORGANISM; KIDNEY; PANCREAS; REGENERATION; SWINE;

ANIMALIA; SUIDAE;

EID: 84864310591     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2012.02065.x     Document Type: Article

References (52)

1. Aigner B, Renner S, Kessler B, Klymiuk N, Kurome M, Wunsch A, Wolf E, 2010: Transgenic pigs as models for translational biomedical research. J Mol Med 88, 653-664.
2. Carver BS, Pandolfi PP, 2006: Mouse modeling in oncologic preclinical and translational research. Clin Cancer Res 12, 5305-5311.
3. Chen JZ, Lansford R, Stewart V, Young F, Alt FW, 1993: RAG-2-deficient blastosyst complementation: an assay of gene function in lymphocyte development. Proc Natl Acad Sci USA 90, 4528-4532.
4. Cooper DK, Dorling A, Pierson RNI, Rees M, Seebach J, Yazer M, Ohdan H, Awwad M, Ayares D, 2007: Alpha1, 3-galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here? Transplantation 84, 1-7.
5. Cozzi E, Langford GA, Richards A, Elsome K, Lancaster R, Chen P, Yannoutsos N, White DJ, 1994: Expression of human decay accelerating factor in transgenic pigs. Transplant Proc 26, 1402-1403.
6. Dai Y, Vaught TD, Boone J, Chen SH, Phelps CJ, Ball S, Monahan JA, Jobst PM, McCreath KJ, Lamborn AE, Cowell-Lucero JL, Wells KD, Colman A, Polejaeva IA, Ayares DL, 2002: Targeted disruption of the alpha1, 3-galactosyltransferase gene in cloned pigs. Nat Biotechnol 20, 251-255.
7. Dauer W, Przedborski S, 2003: Parkinson's disease: mechanisms and models. Neuron 39, 889-909.
8. Du Y, Li J, Kragh PM, Zhang Y, Schmidt M, Bøgh IB, Zhang X, Purup S, Kuwayama M, Jørgensen AL, Pedersen AM, Villemoes K, Yang H, Bolund L, Vajta G, 2007: Piglets born from vitrified cloned blastocysts produced with a simplified method of delipation and nuclear transfer. Cloning Stem Cells 9, 469-476.
9. Evans MJ, Kaufman MH, 1981: Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156.
10. Fodor WL, Williams BL, Matis LA, Madri JA, Rollins SA, Knight JW, Velander W, Squinto SP, 1994: Expression of a functional human-complement inhibitor in a transgenic pig as a model for the prevention of xenogenic hyperacute organ rejection. Proc Natl Acad Sci USA 91, 11153-11157.
11. Grubb BR, Boucher RC, 1999: Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiol Rev 79, S193-S214.
12. Guilbault C, Saeed Z, Downey GP, Radzioch D, 2007: Cystic fibrosis mouse models. Am J Respir Cell Mol Biol 36, 1-7.
13. Hauschild J, Petersen B, Santiago Y, Queisser AL, Carnwath JW, Lucas-Hahn A, Zhang L, Meng XD, Gregory PD, Schwinzer R, Cost GJ, Niemann H, 2011: Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proc Natl Acad Sci USA 108, 12013-12017.
14. Ibrahim Z, Busch J, Awwad M, Wagner R, Wells K, Cooper DK, 2006: Selected physiologic compatibilities and incompatibilities between human and porcine organ systems. Xenotransplantation 13, 488-499.
15. Kishigami S, Mizutani E, Ohta H, Hikichi T, Thuan NV, Wakayama S, Bui HT, Wakayama T, 2006: Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer. Biochem Biophys Res Com 340, 183-189.
16. Kobayashi T, Yamaguchi T, Hamanaka S, Kato-Itoh M, Yamazaki Y, Ibata M, Sato H, Lee YS, Usui J, Knisely AS, Hirabayashi M, Nakauchi H, 2010: Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells. Cell 142, 787-799.
17. Kubota C, Tian XC, Yang X, 2004: Serial bull cloning by somatic cell nuclear transfer. Nat Biotechnol 22, 693-694.
18. Kurome M, Hisatomi H, Matsumoto S, Tomii R, Ueno S, Hiruma K, Saito H, Nakamura K, Okumura K, Matsumoto M, Kaji Y, Endo F, Nagashima H, 2008: Production efficiency and telomere length of the cloned pigs following serial somatic cell nuclear transfer. J Reprod Dev 54, 254-258.
19. Lai L, Kolber-Simonds D, Park KW, Cheong HT, Greenstein JL, Im GS, Samuel M, Bonk A, Rieke A, Day BN, Murphy CN, Carter DB, Hawley RJ, Prather RS, 2002: Production of alpha-1, 3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 295, 1089-1092.
20. Li R, Lai L, Wax D, Hao Y, Murphy CN, Rieke A, Samuel M, Linville ML, Korte SW, Evans RW, Turk JR, Kang JX, Witt WT, Dai Y, Prather RS, 2006: Cloned transgenic swine via in vitro production and cryopreservation. Biol Reprod 75, 226-230.
21. Li RF, Murphy CN, Spate L, Wax D, Isom C, Rieke A, Walters EM, Samuel M, Prather RS, 2009: Production of piglets after cryopreservation of embryos using a centrifugation-based method for delipation without micromanipulation. Biol Reprod 80, 563-571.
22. Lunney JK, 2007: Advances in swine biomedical model genomics. Int J Biol Sci 3, 179-184.
23. Maehara M, Honda K, Nakano K, Matsunari H, Takeuchi Y, Kanai T, Matsuda T, Hagiwara Y, Sasayama N, Shirasu A, Takahashi M, Watanabe M, Umeyama K, Hanazono Y, Nagashima H, 2011: In Vitro Maturation/Fertilization Derived Porcine Morulae can Give Rise to Efficient Piglet Production Following Vitrification by the Hollow Fiber Vitrification (HFV)-Method. World Congress on Reproductive Biology, Cairns, Qld, Australia, pp. 144.
24. Matsunari H, Onodera M, Tada N, Mochizuki H, Karasawa S, Haruyama E, Nakayama N, Saito H, Ueno S, Kurome M, Miyawaki A, Nagashima H, 2008: Transgenic-cloned pigs systemically expressing red fluorescent protein, Kusabira-Orange. Cloning Stem Cells 10, 313-323.
25. Matsunari H, Nakano K, Fujiwara T, Ikezawa Y, Ogawa B, Takayanagi S, Watanabe M, Umeyama K, Nagashima H, 2010: Production of the sixth generation cloned pigs by serial somatic cell nuclear transfer. The 112th Annual Meeting of the Japanese Society of Animal Science. Tokyo, Japan, pp. 82.
26. Matsunari H, Nakano K, Maehara M, Ikezawa Y, Hagiwara Y, Sasayama N, Shirasu A, Takahashi M, Nagashima H, 2011a: Hollow Fiber Vitrification (HFV) Method: A Novel High Performance Embryo Cryopreservation Method. World Congress on Reproductive Biology, Cairns, Qld, Australia, pp. 145.
27. Matsunari H, Yokoo T, Matsumoto K, Yokote S, Iwai S, Medin JA, Watanabe M, Umeyama K, Sato Y, Nakano K, Maehara M, Nagashima H, Kobayashi E, 2011b: A challenge to developing humanized kidney using porcine renal anlagen scaffold. Swine in Biomedical Research Conference 2011. Chicago, IL.
28. Matsunari H, Watanabe M, Umeyama K, Nakano K, Ikezawa U, Kurome M, Kessler B, Wolf E, Miyagawa S, Nakauchi H, Nagashima H, 2012: Cloning of homozygous α1, 3-galactosyltransferase gene knock-out pigs by somatic cell nuclear transfer. In: Miyagawa S (ed.), Xenotransplantation. InTech, Rijeka, Croatia, pp. 37-54.
29. McCurry KR, Kooyman DL, Alvarado CG, Cotterell AH, Martin MJ, Logan JS, Platt JL, 1995: Human-complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury. Nat Med 1, 423-427.
30. Miyagawa S, Shirakura R, Iwata K, Nakata S, Matsumiya G, Izutani H, Matsuda H, Terado A, Matsumoto M, Nagasawa S, Seya T, 1994: Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAE hybrid, on complement-mediated swine endothelial cell lysis. Transplantation 58, 834-840.
31. Nagashima H, Kashiwazaki N, Ashman RJ, Grupen CG, Nettle MB, 1995: Cryopreservation of porcine embryos. Nature 374, 416.
32. Nakano K, Matsunari H, Maehara M, Takeuchi Y, Ogawa B, Matsuda T, Kanai T, Honda K, Hagiwara Y, Sasayama N, Shirasu A, Ohta H, Takahashi M, Nagashima H, 2011a: High Performance Cryopreservation of Porcine Embryos by the Hollow Fiber Vitrification (HFV)-Method. World Congress on Reproductive Biology, Cairns, Qld, Australia, pp. 145-146.
33. Nakano K, Matsunari H, Nakayama N, Ogawa B, Kurome M, Takahashi M, Matsumoto M, Murakami H, Kaji Y, Nagashima H, 2011b: Cloned porcine embryos can maintain developmental ability after cryopreservation at the morula stage. J Reprod Dev 57, 312-316.
34. Niemann H, Kues WA, 2003: Application of transgenesis in livestock for agriculture and biomedicine. Anim Reprod Sci 79, 291-317.
35. Park KW, Cheong HT, Lai L, Im GS, Kühholzer B, Bonk A, Samuel M, Rieke A, Day BN, Murphy CN, Carter DB, Prather RS, 2001: Production of nuclear transfer-derived swine that express the enhanced green fluorescent protein. Anim Biotechnol 12, 173-181.
36. Pearce AI, Richards RG, Milz S, Schneider E, Pearce SG, 2007: Animal models for implant biomaterial research in bone: a review. Eur Cell Mater 13, 1-10.
37. Ramsoondar JJ, Macháty Z, Costa C, Williams BL, Fodor WL, Bondioli KR, 2003: Production of alpha 1, 3-galactosyltransferase-knockout cloned pigs expressing human alpha 1, 2-fucosylosyltransferase. Biol Reprod 69, 437-445.
38. Recchia FA, Lionetti V, 2007: Animal models of dilated cardiomyopathy for translational research. Vet Res Commun 31, 35-41.
39. Rees DA, Alcolado JC, 2005: Animal models of diabetes mellitus. Diabetic Med 22, 359-370.
40. Takahagi Y, Fujimura T, Miyagawa S, Nagashima H, Shigehisa T, Shirakura R, Murakami H, 2005: Production of alpha 1, 3-galactosyltransferase gene knockout pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III. Mol Reprod Dev 71, 331-338.
41. Takahashi K, Yamanaka S, 2006: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
42. Umeyama K, Watanabe M, Saito H, Kurome M, Tohi S, Matsunari H, Miki K, Nagashima H, 2009: Dominant-negative mutant hepatocyte nuclear factor 1 alpha induces diabetes in transgenic-cloned pigs. Transgenic Res 18, 697-706.
43. Wakayama T, Shinkai Y, Tamashiro KL, Niida H, Blanchard DC, Blanchard RJ, Ogura A, Tanemura K, Tachibana M, Perry AC, Colgan DF, Mombaerts P, Yanagimachi R, 2000: Cloning of mice to six generations. Nature 407, 318-319.
44. Watanabe M, Umeyama K, Matsunari H, Takayanagi S, Haruyama E, Nakano K, Fujiwara T, Ikezawa Y, Nakauchi H, Nagashima H, 2010: Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases. Biochem Biophys Res Com 402, 14-18.
45. Whyte JJ, Prather RS, 2011: Genetic modifications of pigs for medicine and agriculture. Mol Reprod Dev 78, 879-891.
46. Yamada K, Yazawa K, Shimizu A, Iwanaga T, Hisashi Y, Nuhn M, O'Malley P, Nobori S, Vagefi PA, Patience C, Fishman J, Cooper DKC, Hawley RJ, Greenstein J, Schuurman HJ, Awwad M, Sykes M, Sachs DH, 2005: Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha 1, 3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med 11, 32-34.
47. Yang YG, Sykes M, 2007: Xenotransplantation: current status and a perspective on the future. Nat Rev Immunol 7, 519-531.
48. Yokoo T, Ohashi T, Shen JS, Sakurai K, Miyazaki Y, Utsunomiya Y, Takahashi M, Terada Y, Eto Y, Kawamura T, Osumi N, Hosoya T, 2005: Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues. Proc Natl Acad Sci USA 102, 3296-3300.
49. Yokoo T, Nagashima H, Matsunari H, Iwai S, Hosoya T, Kobayashi E, 2009: Xeno-metanephros as a biocompetent scaffold for kidney regeneration. Joint Meeting of the IPITA and IXA. Venice, Italy, pp. 359.
50. Zhao JG, Ross JW, Hao YH, Spate LD, Walters EM, Samuel MS, Rieke A, Murphy CN, Prather RS, 2009: Significant improvement in cloning efficiency of an inbred miniature pig by histone deacetylase inhibitor treatment after somatic cell nuclear transfer. Biol Reprod 81, 525-530.
51. Zhao J, Hao Y, Ross JW, Spate LD, Walters EM, Samuel MS, Rieke A, Murphy CN, Prather RS, 2010a: Histone deacetylase inhibitors improve in vitro and in vivo developmental competence of somatic cell nuclear transfer porcine embryos. Cell Reprogram 12, 75-83.
52. Zhao JG, Whyte J, Prather RS, 2010b: Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer. Cell Tissue Res 341, 13-21.