Evaluating chromosomal damage in workers exposed to hexavalent chromium and the modulating role of polymorphisms of DNA repair genes

International Archives of Occupational and Environmental Health

Volumn 85, Issue 5, 2012, Pages 473-481

  Halasova, Erika ^a   Matakova, Tatiana ^a   Musak, Ludovit ^a   Polakova, Veronika ^b   Letkova, Lucia ^a   Dobrota, Dusan ^a   Vodicka, Pavel ^b  

^a University Teaching Hospital in Martin   (Slovakia)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

HOGG1 Ser326Cys; XPC Lys939Gln; XPD Lys751Gln; XPG Asn114His; XRCC1 Arg399Gln

Indexed keywords

CARCINOGEN; CHROMIUM; CHROMIUM HEXAVALENT ION;

ADULT; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHROMOSOME ABERRATION; COMPARATIVE STUDY; DNA REPAIR; DRUG EFFECT; GENETIC POLYMORPHISM; GENETICS; HUMAN; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SLOVAKIA; WELDING;

ADULT; CARCINOGENS, ENVIRONMENTAL; CHROMIUM; CHROMOSOME ABERRATIONS; DNA REPAIR; HUMANS; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; POLYMORPHISM, GENETIC; SLOVAKIA; WELDING;

EID: 84864280844     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-011-0684-x     Document Type: Article

References (70)

1. Abrahim KS, Abdet-Gawad NB, Mahmoud AM, El-Gowaily MM, Emara AM, Hwaihy MM (2011) Genotoxic eVect of occupational exposure to cadmium. Toxicol Ind Health 27:173-179
2. Albertini R, Clewell H, Himmelstein MW, Morinello E, Olin S, Preston J, Scarano L, Smith MT, Swenberg J, Tice R, Travis C (2003) The use of non-tumor data cancer risk assessment reXections on butadiene, vinyl chloride, and benzene. Regul Toxicol Pharm 37:105-132 (Pubitemid 36349342)
3. Angelini S, Kumar R, Carbone F, MaVei F, Forti GC, Violante FS, Lodi V, Curti S, Hemminki K, Hrelia P (2005) Micronuclei in humans induced by exposure to low level of ionizing radiation: inXuence of polymorphisms in DNA repair genes. Mutat Res 570:105-117 (Pubitemid 40179273)
4. Angelini S, Kumar R, Bermejo JL, MaVei F, Barbieri A, Graziosi F, Carbone F, Cantelli-Forti G, Violante FS, Hemminki K, Hrelia P (2011) Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes. Mutat Res 719:7-13
5. Au WW, Salama SA (2006) Cytogenetic challenge assays for assessment of DNA repair capacities. Methods Mol Biol 314:25-42
6. Balachandar V, Arun M, Mohana Devi S, Velmurugan P, Manikantan P, Karthick Kumar A, Sasikala K, Venkatesan C (2010) Evaluation of the genetic alterations in direct and indirect exposures of hexavalent chromium [Cr(VI)] in leather tanning industry workers North Arcot District, South India. Int Arch Occup Environ Health 83:791-801
7. Berwick M, Vineis P (2000) Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review. J Natl Cancer Inst 92:874-897 (Pubitemid 30429188)
8. Beveridge R, Pintos J, Parent ME, Asselin J, Siemiatycki J (2010) Lung cancer risk associated with occupational exposure to nickel, chromium VI, and cadmium in two population-based case-control studies in Montreal. Am J Ind Med 53:476-485
9. Brand P, Gube M, Gerards K, Bertram J, Kaminski H, John AC, Kuhlbusch T, Wiemann M, Eisenbeis C, Winkler R, Kraus T (2010) Internal exposure, eVect monitoring, and lung function in welders after acute short-term exposure to welding fumes from diVerent welding processes. J Occup Environ Med 52:887-892
10. Bryant PE, Riches AC, Terry SY (2010) Mechanisms of the formation of radiation-induced chromosomal aberrations. Mutat Res 701:23-26
11. Chen J, Suter B (2003) XPD a structural bridge and a functional link. Cell Cycle 2:503-506
12. Christmann M, Tomicic MT, Roos WP, Kaina B (2003) Mechanisms of human DNA repair: an update. Toxicology 193:3-34 (Pubitemid 37340141)
13. Crespo-López ME, Macêdo GL, Arrifano GP, Pinheiro Mda C, do Nascimento JL, Herculano AM (2011) Genotoxicity of mercury: contributing for the analysis of Amazonian populations. Environ Int 37:136-141
14. Dai H, Liu J, Malkas LH, Catalano J, Alagharu S, Hickey RJ (2009) Chromium reduces the in vitro activity and Wdelity of DNA replication mediated by the human cell DNA synthesome. Toxicol Appl Pharmacol 236:154-165
15. Figgitt M, Newson R, Leslie IJ, Fisher J, Ingham E, Case CP (2010) The genotoxicity of physiological concentrations of chromium (Cr(III) and Cr(VI)) and cobalt (Co(II)): an in vitro study. Mutat Res 688:53-61
16. Franco SS, Nardocci AC, Günther WM (2008) PAH biomarkers for human health risk assessment: a review of the state-of-the-art. Cad Saude Publica Suppl 4:569-580
17. Friedberg EC (2001) How nucleotide excision repair protects against cancer. Nat Rev Cancer 1:22-33 (Pubitemid 33741878)
18. García-Lestón J, Méndez J, Pásaro E, LaVon B (2010) Genotoxic eVects of lead: an updated review. Environ Int 36:623-636
19. Ghosh M, Bandyopadhyay M, Mukherjee A (2010) Genotoxicity of titanium dioxide (TiO2) nanoparticles at two trophic levels: plant and human lymphocytes. Chemosphere 81:1253-1262
20. Grlickova-Duzevik E, Wise SS, Munroe RC, Thompson WD, Wise JP Sr (2006) XRCC1 protects against particulate chromate-induced chromosome damage and cytotoxicity in Chinese hamster ovary cells. Toxicol Sci 92:96-102 (Pubitemid 43985794)
21. Halasova E, Bukovska E, Kukura F, Cervenova T, Oravec P, Kereskeni J (2001) Do works concerning ferrochromium alloys mean risk for inhabitants living in their surrounding? A cytogenetic study. Biologia 56:679-683
22. Halasova E, Baska T, Kukura F, Mazurova D, Bukovska E, Dobrota D, Poliacek I, Halasa M (2005) Lung cancer in relation to occupational and environmental chromium exposure and smoking. Neoplasma 52:287-291 (Pubitemid 41076194)
23. Hanawalt PC (2002) Subpathways of nucleotide excision repair and their regulation. Oncogene 21:8949-8956 (Pubitemid 36110824)
24. Hashiguchi K, Stuart JA, de Souza-Pinto NC, Bohr VA (2004) The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity. Nucleic Acids Res 32:5596-5608 (Pubitemid 39545676)
25. Haveric A, Haveric S, Ibrulj S (2010) Micronuclei frequencies in peripheral blood and buccal exfoliated cells of young smokers and non-smokers. Toxicol Mech Methods 20:260-266
26. Hodges NJ, Chipman JK (2002) Down-regulation of the DNA-repair endonuclease 8-oxo-guanine DNA glycosylase 1 (hOGG1) by sodium dichromate in cultured human A549 lung carcinoma cells. Carcinogenesis 23:55-60 (Pubitemid 34213551)
27. Hopf NB, Kirkeleit J, Kramer SL, Moen B, Succop P, Genter MB, Carreon T, Mack J, Talaska G (2010) Urinary 1-hydroxypyrene levels in oVshore workers. Int Arch Occup Environ Health 83:55-59
28. Hu YC, Ahrendt SA (2005) hOGG1 Ser326Cys polymorphism and G:C-to-T:A mutations: no evidence for a role in tobacco-related non small cell lung cancer. Int J Cancer 114:387-393 (Pubitemid 40279958)
29. IARC (International Agency for Research on Cancer) (1990) IARC monographs on the evaluation of carcinogenic risks to humans, vol 49: chromium nickel and welding. Lyon, France, pp 249-256
30. Iarmarcovai G, Sari-Minodier I, Chaspoul F, Botta C, De Meo M, Orsiere T, Berge-Lefranc JL, Gallice P, Botta A (2005) Risk assessment of welders using analysis of eight metals by ICP-MS in blood and urine and DNA damage evaluation by the comet and micronucleus assays; inXuence of XRCC1and XRCC3 polymorphisms. Mutagenesis 20:425-432 (Pubitemid 41816529)
31. Jakusova V, Murajda L, Poliacek I, Jakus J (2010) Risk of ultraviolet radiation-health protection of university student. Acta Med Mart 7:26-30
32. Kiuru A, Lindholm C, Heilimo I, Ceppi M, Koivistoinen A, Ilus T, Hirvonen A, Norppa H, Salomaa S (2005) InXuence of DNA repair gene polymorphisms on the yield of chromosomal aberrations. Environ Mol Mutagen 46:198-205 (Pubitemid 41642312)
33. Kohno T, Kunitoh H, Toyama K, Yamamoto S, Kuchiba A, Saito D, Yanagitani N, Ishihara S, Saito R, Yokota J (2006) Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk. Cancer Sci 97:724-728 (Pubitemid 43983784)
34. Kubrak OI, Lushchak OV, Lushchak JV, Torous IM, Storey JM, Storey KB, Lushchak VI (2010) Chromium eVects on free radical processes in goldWsh tissues: Comparison of Cr(III) and Cr(VI) exposures on oxidative stress markers, glutathione status and antioxidant enzymes. Comp Biochem Physiol C Toxicol Pharmacol 152:360-370
35. Ladeira C, Viegas S, Carolino E, Prista J, Gomes MC, Brito M (2011) Genotoxicity biomarkers in occupational exposure to formaldehyde - The case of histopathology laboratories. Mutat Res 721:15-20
36. Lee AJ, Hodges NJ, Chipman JK (2005) Interindividual variability in response to sodium dichromate-induced oxidative DNA damage: role of the Ser326Cys polymorphism in the DNA-repair protein of 8-oxo-7,8-dihydro-2- deoxyguanosine DNA glycosylase 1. Cancer Epidemiol Biomarkers Prev 14:497-505 (Pubitemid 40270117)
37. Leonard SS, Roberts JR, Antonini JM, Castranova V, Shi X (2004) PBCrO4 mediates cellular responses via reactive oxygen species. Mol Cell Biochem 255:171-179 (Pubitemid 38159777)
38. Mambo E, Chatterjee A, de Souza-Pinto NC, Mayard S, Hogue BA, Hoque MO, Dizdaroglu M, Bohr VA, Sidransky D (2005) Oxidized guanine lesions and hOgg1 activity in lung cancer. Oncogene 24:4496-4508 (Pubitemid 41032613)
39. Meeker JD, Susi P, Flynn MR (2010) Hexavalent chromium exposure and control in welding tasks. J Occup Environ Hyg 11:607-615
40. Miller BG, Fransman W, Heederik D, Hurley JF, Kromhout H, Fitzsimons E (2010) A review of the data quality and comparability of case-control studies of low-level exposure to benzene in the petroleum industry. Int Arch Occup Environ Health 83:69-76
41. Møller P, Knudsen LE, Loft S, Wallin H (2000) The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and eVect of confounding factors. Cancer Epidemiol Biomarkers Prev 9:1005-1015
42. Musak L, Vodicka P, Klimentova G, Soucek P, Hanova M, Mikulkova R, Buchancova J, Vodickova L, Polakova V, Pec M (2006) Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to cytostatics. Neuro Endocrinol Lett 27(Suppl 2):57-60 (Pubitemid 46534338)
43. Musak L, Soucek P, Vodickova L, Naccarati A, Halasova E, Polakova V, Slyskova J, Susova S, Buchancova J, Smerhovsky Z, Sedikova J, Klimentova G, Osina O, Hemminki K, Vodicka P (2008) Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes. Mut Res 641:36-42
44. Natarajan AT, Obe G (1980) Screening of human populations for mutations induced by environmental pollutants: use of human lymphocyte system. Ecotoxicol Environ Saf 4:468-481 (Pubitemid 11185350)
45. Pantelias GE, Terzoudi GI (2010) Functional cell-cycle chromatin conformation changes in the presence of DNA damage result into chromatid breaks: a new insight in the formation of radiation-induced chromosomal aberrations based on the direct observation of interphase chromatin. Mutat Res 701:27-37
46. Pavanello S, Bollati V, Pesatori AC, Kapka L, Bolognesi C, Bertazzi PA, Baccarelli A (2009) Global and gene-speciWc promoter methylation changes are related to anti-B[a] PDE-DNA adduct levels and inXuence micronuclei levels in polycyclic aromatic hydrocarbon- exposed individuals. Int J Cancer 125:1692-1697
47. Pavanello S, Pesatori AC, Dioni L, Hoxha M, Bollati V, Siwinska E, Mielzyjska D, Bolognesi C, Bertazzi PA, Baccarelli A (2010) Shorter telomere length in peripheral blood lymphocytes of workers exposed to polycyclic aromatic hydrocarbons. Carcinogenesis 31:216-221
48. Polakova V, Pardini B, Naccarati A, Landi S, Slyskova J, Novotny J, Vodickova L, Bermejo JL, Hanova M, Smerhovsky Z, Tulupova E, Kumar R, Hemminki K, Vodicka P (2009) Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic. Hum Mutat 30:661-668
49. Qu T, Morii E, Oboki K, Lu Y, Morimoto K (2005) Micronuclei in EM9 cells expressing polymorphic forms of human XRCC1. Cancer Lett 221:91-95 (Pubitemid 40387912)
50. Quievryn G, Messer J, Zhitkovich A (2002) Carcinogenic chromium (VI) induces cross-linking of vitamin C to DNA in vitro and in human lungs A549 cells. Biochemistry 41:3156-3167 (Pubitemid 34184647)
51. Rodrigues CF, Urbano AM, Matoso E, Carreira I, Almeida A, Santos P, Botelho F, Carvalho L, Alves M, Monteiro C, Costa AN, Moreno V, Alpoim MC (2009) Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability. Mutat Res 670:42-52
52. Rondelli CM, El-Zein RA, WickliVe JK, Etzel CJ, Abdel-Rahman SZ (2010) A comprehensive haplotype analysis of the XPC genomic sequence reveals a cluster of genetic variants associated with sensitivity to tobacco-smoke mutagens. Toxicol Sci 115:41-50
53. Rossi AM, Hansteen IL, Skjelbred CF, Ballardin M, Maggini V, Murgia E, Tomei A, Viarengo P, Knudsen LE, Barale R, Norppa H, Bonnassi S (2009) Association between frequency of chromosomal aberrations and cancer risk is not inXuenced by genetic polymorphisms in GSTM1 and GSTT1. Environ Health Perspect 117:203-208
54. Rzeszowska-Wolny J, Polanska J, Pietrowska M, Palyvoda O, Jaworska J, Butkiewicz D, Hancock R (2005) InXuence of polymorphisms in DNA repair genes XPD, XRCC1 and MGMT on DNA damage induced by gamma radiation and its repair in lymphocytes in vitro. Radiat Res 164:132-140 (Pubitemid 41045593)
55. Singh S, Kumar V, Thakur S, Banerjee BD, Rautela RS, Grover SS, Rawat DS, Pasha ST, Jain SK, Ichhpujani RL, Rai A (2011) Paraoxonase-1 genetic polymorphisms and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides. Toxicol Appl Pharmacol 252:130-137
56. Skjelbred CF, Svendsen M, Haugan V, Eek AK, Clausen KO, Svendsen MV, Hansteen IL (2006) InXuence of DNA repair gene polymorphisms of hOGG1, XRCC1, XRCC3, ERCC2 and the folate metabolism gene MTHFR on chromosomal aberration frequencies. Mutat Res 602:151-162 (Pubitemid 44693567)
57. Skjelbred CF, Svendsen M, Haugan V, Eek AK, Clausen KO, Kure EH, Tuimala JT, Svendsen MV, Norpa H (2011) InXuence of GSTM1, GSTT1, GSTP1, NAT 1, NAT2, EXPHX1, and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes. Carcinogenesis 32:399-405
58. Srivastava RK, Lohani M, Pant AB, Rahman Q (2010) Cyto-genotoxicity of amphibole asbestos Wbers in cultured human lung epithelial cell line: role of surface iron. Toxicol Ind Health 26:575-582
59. Sun P, Qian J, Zhang ZB, Wan JX, Wu F, Jin XP, Fan WW, Lu DR, Zhao NQ, Christiani DC, Xia ZL (2008) Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population. Carcinogenesis 29:2325-2329
60. Tajima H, Yoshida T, Ohnuma A, Fukuyama T, Hayashi K, Yamaguchi S, Ohtsuka R, Sasaki J, Tomita M, Kojima S, Takahashi N, Kashimoto Y, Kuwahara M, Takeda M, Kosaka T, Nakashima N, Harada T (2010) Pulmonary injury and antioxidant response in mice exposed to arsenate and hexavalent chromium and their combination. Toxicology 267:118-124
61. Tsaousi A, Jones E, Case CP (2010) The in vitro genotoxicity of orthopaedic ceramic (Al2O3) and metal (CoCr alloy) particles. Mut Res 697:1-9
62. Velma V, Tchounwou PB (2010) Chromium-induced biochemical, genotoxic and histopathologic eVects in liver and kidney of gold- Wsh, carassius auratus. Mut Res 698:43-51
63. Vidal AE, Boiteux S, Hickson ID, Radicella P (2001) XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions. EMBO J 20:6530-6539 (Pubitemid 33078725)
64. Vodicka P, Stetina R, Polakova V, Tulupova E, Naccarati A, Vodickova L, Kumar R, Hanova M, Pardini B, Slyskova J, Musak L, De Palma G, Soucek P, Hemminki K (2007) Association of DNA repair polymorphisms with DNA repair functional outcomes in healthy human subjects. Carcinogenesis 28:657-664 (Pubitemid 46523361)
65. Vodicka P, Polivkova Z, Sytarova S, Demova H, Kucerova M, Vodickova L, Polakova V, Naccarati A, Smerhovsky Z, Ambrus M, Cerna M, Hemminki K (2010) Chromosomal damage in peripheral blood lymphocytes of newly diagnosed cancer patients and healthy controls. Carcinogenesis 1:1238-1241
66. Wood RD, Mitchell M, Sgouros J, Lindahl T (2001) Human DNA repair genes. Science 291:1284-1289 (Pubitemid 32173086)
67. Wu F, Zhang Z, Wan J, Gu S, Liu W, Jin X, Xia Z (2008) Genetic polymorphisms in hMTH1, hOGG1 and hMYH and risk of chronic benzene poisoning in a Chinese occupational population. Toxicol Appl Pharmacol 233:447-453
68. Yamane A, Kohno T, Ito K, Sunaga N, Aoki K, Yoshimura K, Murakami H, Nojima Y, Yokota J (2004) DiVerential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo. Carcinogenesis 25:1689-1694 (Pubitemid 39214311)
69. Zafereo ME, Sturgis EM, Liu Z, Wang LE, Wei Q, Li G (2009) Nucleotide excision repair core gene polymorphisms and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck. Carcinogenesis 30:997-1002
70. Zhang JY, Wang Y, Prakash C (2006) Xenobiotic-metabolizing enzymes in human lung. Curr Drug Metab 8:939-948 (Pubitemid 44873716)