Chromium reduces the in vitro activity and fidelity of DNA replication mediated by the human cell DNA synthesome

Toxicology and Applied Pharmacology

Volumn 236, Issue 2, 2009, Pages 154-165

  Dai, Heqiao ^a   Liu, Jianying ^a   Malkas, Linda H ^a   Catalano, Jennifer ^a   Alagharu, Srilakshmi ^a   Hickey, Robert J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chromium ion; DNA replication fidelity; Human cell DNA synthesome; Origin dependent in vitro DNA replication

Indexed keywords

CELL DNA; CHROMIUM; CHROMIUM CHLORIDE; DICHROMATE SODIUM; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; PROTEIN SYNTHESOME; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CONTROLLED STUDY; CYTOTOXICITY; DNA REPLICATION; DNA SYNTHESIS; GENE DELETION; GENE INSERTION; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TOXICITY TESTING;

CELL CYCLE; CHROMIUM; DNA; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; HELA CELLS; HUMANS; MULTIENZYME COMPLEXES; TIME FACTORS;

EID: 62549167048     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.12.028     Document Type: Article

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