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Volumn 40, Issue 4, 2012, Pages 721-733

Zhenqing recipe improves glucose metabolism and insulin sensitivity by repressing hepatic FOXO1 in type 2 diabetic rats

Author keywords

Forkhead Box O1; Glucokinase; Gluconeogenesis; Type 2 Diabetes; Zhenqing Recipe

Indexed keywords

BETA ACTIN; FORKHEAD BOX O1 PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HERBACEOUS AGENT; INSULIN; MESSENGER RNA; METFORMIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); STREPTOZOCIN; UNCLASSIFIED DRUG; ZHENQING;

EID: 84864256344     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X12500541     Document Type: Article
Times cited : (12)

References (33)
  • 1
    • 2342496712 scopus 로고    scopus 로고
    • FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
    • DOI 10.1016/S0092-8674(04)00452-0, PII S0092867404004520
    • Accili, D. and K.C. Arden. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117: 421-426, 2004. (Pubitemid 38610228)
    • (2004) Cell , vol.117 , Issue.4 , pp. 421-426
    • Accili, D.1    Arden, K.C.2
  • 3
    • 0141839103 scopus 로고    scopus 로고
    • Novel concepts in insulin regulation of hepatic gluconeogenesis
    • Barthel, A. and D. Schmoll. Novel concepts in insulin regulation of hepatic gluconeogenesis. Am. J. Physiol. Endocrinol. Metab. 285: 685-692, 2003.
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285 , pp. 685-692
    • Barthel, A.1    Schmoll, D.2
  • 4
    • 0035011295 scopus 로고    scopus 로고
    • Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus
    • Boden, G., X. Chen and T.P. Stein. Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus. Am. J. Physiol. Endocrinol. Metab. 280: 23-30, 2001.
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.280 , pp. 23-30
    • Boden, G.1    Chen, X.2    Stein, T.P.3
  • 6
    • 45549090182 scopus 로고    scopus 로고
    • Inactivation of hepatic foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
    • DOI 10.1016/j.cmet.2008.06.006, PII S1550413108001770
    • Dong, X.C., K.D. Copps, S. Guo, Y. Li, R. Kollipara, R.A. DePinho and M.F. White. Inactivation of hepatic foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metab. 8: 65-76, 2008. (Pubitemid 351863393)
    • (2008) Cell Metabolism , vol.8 , Issue.1 , pp. 65-76
    • Dong, X.C.1    Copps, K.D.2    Guo, S.3    Li, Y.4    Kollipara, R.5    Depinho, R.A.6    White, M.F.7
  • 7
    • 71449105535 scopus 로고    scopus 로고
    • FOXO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol
    • Ganjam, G.K., E.Y. Dimova, T.G. Unterman and T. Kietzmann. FOXO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol. J. Biol. Chem. 84: 30783-30797, 2009.
    • (2009) J. Biol. Chem. , vol.84 , pp. 30783-30797
    • Ganjam, G.K.1    Dimova, E.Y.2    Unterman, T.G.3    Kietzmann, T.4
  • 8
    • 80054935481 scopus 로고    scopus 로고
    • Evaluation of antidiabetic potential of selected traditional Chinese medicines in STZ-induced diabetic mice
    • He, K., X. Li, X. Chen, X. Ye, J. Huang, Y. Jin, P. Li, Y. Deng, Q. Jin, Q. Shi, and H. Shu. Evaluation of antidiabetic potential of selected traditional Chinese medicines in STZ-induced diabetic mice. J. Ethnopharmacol. 137: 1135-1142, 2011.
    • (2011) J. Ethnopharmacol. , vol.137 , pp. 1135-1142
    • He, K.1    Li, X.2    Chen, X.3    Ye, X.4    Huang, J.5    Jin, Y.6    Li, P.7    Deng, Y.8    Jin, Q.9    Shi, Q.10    Shu, H.11
  • 9
    • 0038645860 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor
    • DOI 10.1074/jbc.C200553200
    • Hirota, K., H. Daitoku, H. Matsuzaki, N. Araya, K. Yamagata, S. Asada, T. Sugaya and A. Fukamizu. Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor. J. Biol. Chem. 278: 13056-13060, 2003. (Pubitemid 36800073)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.15 , pp. 13056-13060
    • Hirota, K.1    Daitoku, H.2    Matsuzaki, H.3    Araya, N.4    Yamagata, K.5    Asada, S.6    Sugaya, T.7    Fukamizu, A.8
  • 10
    • 57749116021 scopus 로고    scopus 로고
    • A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding
    • Hirota, K., J. Sakamaki, J. Ishida, Y. Shimamoto, S. Nishihara, N. Kodama, K. Ohta, M. Yamamoto, K. Tanimoto and A. Fukamizu. A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding. J. Biol. Chem. 47: 32432-32441, 2008.
    • (2008) J. Biol. Chem. , vol.47 , pp. 32432-32441
    • Hirota, K.1    Sakamaki, J.2    Ishida, J.3    Shimamoto, Y.4    Nishihara, S.5    Kodama, N.6    Ohta, K.7    Yamamoto, M.8    Tanimoto, K.9    Fukamizu, A.10
  • 11
    • 77956188526 scopus 로고    scopus 로고
    • Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db mice
    • Hirotsugu, T., N. Takeyuki, S. Akiyoshi, U. Yasuharu, S. Teruhiko and S. Masayuki. Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db mice. Eur. J. Pharmacol. 645: 185-191, 2010.
    • (2010) Eur. J. Pharmacol. , vol.645 , pp. 185-191
    • Hirotsugu, T.1    Takeyuki, N.2    Akiyoshi, S.3    Yasuharu, U.4    Teruhiko, S.5    Masayuki, S.6
  • 13
    • 0342614209 scopus 로고    scopus 로고
    • Unified nomenclature for the winged helix/forkhead transcription factors
    • Kaestner, K.H., W. Knochel and D.E. Martinez. Unified nomenclature for the winged helix/forkhead transcription factors. Gene Dev. 14: 142-146, 2000. (Pubitemid 30070978)
    • (2000) Genes and Development , vol.14 , Issue.2 , pp. 142-146
    • Kaestner, K.H.1    Knochel, W.2    Martinez, D.E.3
  • 14
  • 16
    • 33646469095 scopus 로고    scopus 로고
    • Lipid lowering activity of Eclipta prostrata in experimental hyperlipidemia
    • Kumari, C.S., S. Govindasamy and E. Sukumar. Lipid lowering activity of Eclipta prostrata in experimental hyperlipidemia. J. Ethnopharmacol. 105: 332-335. 2006.
    • (2006) J. Ethnopharmacol. , vol.105 , pp. 332-335
    • Kumari, C.S.1    Govindasamy, S.2    Sukumar, E.3
  • 17
    • 0029037725 scopus 로고
    • A new insulin-sensitivity index for epidemiological study
    • Li, G.W. and X.R. Pan. A new insulin-sensitivity index for epidemiological study. Chin. Med. J. 108: 55-56, 1995.
    • (1995) Chin. Med. J. , vol.108 , pp. 55-56
    • Li, G.W.1    Pan, X.R.2
  • 18
    • 0026488079 scopus 로고
    • Increased rate of gluconeogenesis in type II diabetes mellitus: A 13C nuclear magnetic resonance study
    • Magnuson, M.A., D.L. Rothman, L.D. Katz, R.G. Shulman and G.I. Shulman. Increased rate of gluconeogenesis in type II diabetes mellitus: A 13C nuclear magnetic resonance study. J. Clin. Invest. 90: 1322-1327, 1992.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1322-1327
    • Magnuson, M.A.1    Rothman, D.L.2    Katz, L.D.3    Shulman, R.G.4    Shulman, G.I.5
  • 19
    • 34548349302 scopus 로고    scopus 로고
    • Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver
    • DOI 10.1016/j.cmet.2007.08.006, PII S1550413107002288
    • Matsumoto, M., A. Pocai, L. Rossetti, R.A. Depinho and D. Accili. Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver. Cell Metab. 6: 208-216, 2007. (Pubitemid 47336849)
    • (2007) Cell Metabolism , vol.6 , Issue.3 , pp. 208-216
    • Matsumoto, M.1    Pocai, A.2    Rossetti, L.3    Depinho, R.A.4    Accili, D.5
  • 20
    • 0036787607 scopus 로고    scopus 로고
    • Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
    • Nakae, J., W.H. Biggs, T. Kitamura, W. Cavenee, C.V. Wright, K.C. Arden and D. Accili. Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet. 32: 245-253, 2002.
    • (2002) Nat. Genet. , vol.32 , pp. 245-253
    • Nakae, J.1    Biggs, W.H.2    Kitamura, T.3    Cavenee, W.4    Wright, C.V.5    Arden, K.C.6    Accili, D.7
  • 21
    • 0036077035 scopus 로고    scopus 로고
    • Elevated basal PI-3 kinase activity and reduced insulin signaling in sucrose induced hepatic insulin resistance
    • Pagliassotti, M.J., J. Kang, J.S. Thresher, C.K. Sung and M.E. Bizeau. Elevated basal PI-3 kinase activity and reduced insulin signaling in sucrose induced hepatic insulin resistance. Am. J. Physiol. Endocrinol. Metab. 282: 170-176, 2002.
    • (2002) Am. J. Physiol. Endocrinol. Metab. , vol.282 , pp. 170-176
    • Pagliassotti, M.J.1    Kang, J.2    Thresher, J.S.3    Sung, C.K.4    Bizeau, M.E.5
  • 23
    • 78149445050 scopus 로고    scopus 로고
    • Radix astragali (huangqi) as a treatment for defective hypoglycemia counterregulation in diabetes
    • Sang, Z., L. Zhou, X. Fan and R.J. McCrimmon. Radix astragali (huangqi) as a treatment for defective hypoglycemia counterregulation in diabetes. Am. J. Chin. Med. 38: 1027-1038, 2010
    • (2010) Am. J. Chin. Med. , vol.38 , pp. 1027-1038
    • Sang, Z.1    Zhou, L.2    Fan, X.3    McCrimmon, R.J.4
  • 24
    • 77249107739 scopus 로고    scopus 로고
    • Metformin reduces lipid accumulation in macrophages by inhibiting FOXO1-mediated transcription of fatty acidbinding protein 4
    • Song, J., P. Ren, L. Zhang, X.L. Wang, L. Chen and Y.H. Shen. Metformin reduces lipid accumulation in macrophages by inhibiting FOXO1-mediated transcription of fatty acidbinding protein 4. Biochem. Biophys. Res. Commun. 393: 89-94, 2010.
    • (2010) Biochem. Biophys. Res. Commun. , vol.393 , pp. 89-94
    • Song, J.1    Ren, P.2    Zhang, L.3    Wang, X.L.4    Chen, L.5    Shen, Y.H.6
  • 25
    • 0030991979 scopus 로고    scopus 로고
    • A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin
    • DOI 10.1074/jbc.272.18.11698
    • Streeper, R.S., C.A. Svitek, S. Chapman, L.E. Greenbaum, R. Taub and R.M. O'Brien. A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6- phosphatase gene transcription by insulin. J. Biol. Chem. 272: 11698-11701, 1997. (Pubitemid 27202731)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.18 , pp. 11698-11701
    • Streeper, R.S.1    Svitek, C.A.2    Chapman, S.3    Greenbaum, L.E.4    Taub, R.5    O'Brien, R.M.6
  • 26
    • 73649098762 scopus 로고    scopus 로고
    • Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice
    • Wang, Z.H., C.C. Hsu, C.N. Huang and M.C. Yin. Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice. Eur. J. Pharmacol. 628: 255-260, 2010.
    • (2010) Eur. J. Pharmacol. , vol.628 , pp. 255-260
    • Wang, Z.H.1    Hsu, C.C.2    Huang, C.N.3    Yin, M.C.4
  • 27
    • 41149151132 scopus 로고    scopus 로고
    • Effect of Zhengqing Recipe in the treatment of 50 senile patients with diabetic nephropathy
    • Wen, X.Y., L. Xiong, H. Liu and Q.H. Wang. Effect of Zhengqing Recipe in the treatment of 50 senile patients with diabetic nephropathy. Herald of Medicine 25: 782-784, 2006.
    • (2006) Herald of Medicine , vol.25 , pp. 782-784
    • Wen, X.Y.1    Xiong, L.2    Liu, H.3    Wang, Q.H.4
  • 29
    • 84861967049 scopus 로고    scopus 로고
    • Zhenqing recipe alleviates diabetic nephropathy in experimental type 2 diabetic rats through suppression of SREBP-1c
    • Wen, X.Y., Y.L. Zeng, L.F. Liu, H. Zhang, W.G. Xu, N.X. Li and X.M. Jia. Zhenqing recipe alleviates diabetic nephropathy in experimental type 2 diabetic rats through suppression of SREBP-1c. J. Ethnopharmacol. 142: 144-150, 2012.
    • (2012) J. Ethnopharmacol. , vol.142 , pp. 144-150
    • Wen, X.Y.1    Zeng, Y.L.2    Liu, L.F.3    Zhang, H.4    Xu, W.G.5    Li, N.X.6    Jia, X.M.7
  • 31
    • 1642464560 scopus 로고    scopus 로고
    • Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: Characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms
    • DOI 10.1042/BJ20031450
    • Zhao, X., L. Gan, H. Pan, D. Kan, M. Majeski, S.A. Adam and T.G. Unterman. Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: Characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. Biochem. J. 378: 839-849, 2004. (Pubitemid 38406861)
    • (2004) Biochemical Journal , vol.378 , Issue.3 , pp. 839-849
    • Zhao, X.1    Gan, L.2    Pan, H.3    Kan, D.4    Majeski, M.5    Adam, S.A.6    Unterman, T.G.7
  • 33
    • 0029955947 scopus 로고    scopus 로고
    • Insulin resistance in the NIDDM model Psammomys obesus in the normoglycaemic, normoinsulinaemic state
    • DOI 10.1007/s001250050569
    • Ziv, E., R. Kalman, K. Hershkop, V. Barash, E. Shafrir and H. Bar-On. Insulin resistance in the NIDDM model Psammomys obesus in the normoglycaemic, normoinsulinemic state. Diabetologia 39: 1269-1275, 1996. (Pubitemid 26356053)
    • (1996) Diabetologia , vol.39 , Issue.11 , pp. 1269-1275
    • Ziv, E.1    Kalman, R.2    Hershkop, K.3    Barash, V.4    Shafrir, E.5    Bar-On, H.6


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