Osteomimicry of mammary adenocarcinoma cells in vitro; increased expression of bone matrix proteins and proliferation within a 3D collagen environment

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Cox, Rachel F ^a   Jenkinson, Allan ^a   Pohl, Kerstin ^a   O'Brien, Fergal J ^a,b   Morgan, Maria P ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; BONE MORPHOGENETIC PROTEIN 2; BONE SIALOPROTEIN; COLLAGEN TYPE 1; DEXAMETHASONE; GLYCOSAMINOGLYCAN; HYDROXYAPATITE; ORGANOPHOSPHATE; PHOSPHATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE METASTASIS; BONE MINERALIZATION; BREAST ADENOCARCINOMA; CANCER GROWTH; CARCINOMA CELL; CONTROLLED STUDY; DOSE RESPONSE; ENRICHMENT CULTURE; IN VITRO STUDY; MOLECULAR IMAGING; MOLECULAR MIMICRY; MOLECULAR MODEL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; THREE DIMENSIONAL IMAGING; TUMOR MICROENVIRONMENT;

ADENOCARCINOMA; ANIMALS; BONE MATRIX; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL LINE, TUMOR; CELL PROLIFERATION; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLYCEROPHOSPHATES; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; NEOPLASM PROTEINS; OSTEOGENESIS; PHOSPHATES; REAL-TIME POLYMERASE CHAIN REACTION; TISSUE SCAFFOLDS; TUMOR MARKERS, BIOLOGICAL;

MURINAE;

EID: 84864245984     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041679     Document Type: Article

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