메뉴 건너뛰기




Volumn 7, Issue 7, 2012, Pages

Vascular disrupting agent drug classes differ in effects on the cytoskeleton

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; COMBRETASTATIN A4; MITOFLAXONE; TUBULIN; VADIMEZAN; VASCULAR TARGETING AGENT;

EID: 84864182337     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040177     Document Type: Article
Times cited : (23)

References (31)
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • Folkman J, (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 4
    • 33845961014 scopus 로고    scopus 로고
    • Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies
    • Shih T, Lindley C, (2006) Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. Clin Ther 28: 1779-1802.
    • (2006) Clin Ther , vol.28 , pp. 1779-1802
    • Shih, T.1    Lindley, C.2
  • 5
    • 0030951899 scopus 로고    scopus 로고
    • Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
    • Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, et al. (1997) Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 57: 1829-1834.
    • (1997) Cancer Res , vol.57 , pp. 1829-1834
    • Dark, G.G.1    Hill, S.A.2    Prise, V.E.3    Tozer, G.M.4    Pettit, G.R.5
  • 6
    • 0028124643 scopus 로고
    • Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents
    • Zwi LJ, Baguley BC, Gavin JB, Wilson WR, (1994) Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents. Oncol Res 6: 79-85.
    • (1994) Oncol Res , vol.6 , pp. 79-85
    • Zwi, L.J.1    Baguley, B.C.2    Gavin, J.B.3    Wilson, W.R.4
  • 7
    • 0026047751 scopus 로고
    • Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization
    • Cushman M, Nagarathnam D, Gopal D, Chakraborti AK, Lin CM, et al. (1991) Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization. J Med Chem 34: 2579-2588.
    • (1991) J Med Chem , vol.34 , pp. 2579-2588
    • Cushman, M.1    Nagarathnam, D.2    Gopal, D.3    Chakraborti, A.K.4    Lin, C.M.5
  • 8
    • 0022589148 scopus 로고
    • Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice
    • Plowman J, Narayanan VL, Dykes D, Szarvasi E, Briet P, et al. (1986) Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice. Cancer Treat Rep 70: 631-635.
    • (1986) Cancer Treat Rep , vol.70 , pp. 631-635
    • Plowman, J.1    Narayanan, V.L.2    Dykes, D.3    Szarvasi, E.4    Briet, P.5
  • 9
    • 0037341637 scopus 로고    scopus 로고
    • Antivascular therapy of cancer: DMXAA
    • Baguley BC, (2003) Antivascular therapy of cancer: DMXAA. Lancet Oncol 4: 141-148.
    • (2003) Lancet Oncol , vol.4 , pp. 141-148
    • Baguley, B.C.1
  • 10
    • 79953648492 scopus 로고    scopus 로고
    • Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer
    • Zweifel M, Jayson GC, Reed NS, Osborne R, Hassan B, et al. (2011) Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer. Ann Oncol 22: 2036-2041.
    • (2011) Ann Oncol , vol.22 , pp. 2036-2041
    • Zweifel, M.1    Jayson, G.C.2    Reed, N.S.3    Osborne, R.4    Hassan, B.5
  • 11
    • 74549118938 scopus 로고    scopus 로고
    • The development of the tumor vascular-disrupting agent ASA404 (vadimezan, DMXAA): current status and future opportunities
    • Head M, Jameson MB, (2010) The development of the tumor vascular-disrupting agent ASA404 (vadimezan, DMXAA): current status and future opportunities. Expert Opin Investig Drugs 19: 295-304.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 295-304
    • Head, M.1    Jameson, M.B.2
  • 12
    • 80051638135 scopus 로고    scopus 로고
    • Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer
    • Lara PN Jr, Douillard JY, Nakagawa K, von Pawel J, McKeage MJ, et al. (2011) Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer. J Clin Oncol 29: 2965-2971.
    • (2011) J Clin Oncol , vol.29 , pp. 2965-2971
    • Lara Jr., P.N.1    Douillard, J.Y.2    Nakagawa, K.3    von Pawel, J.4    McKeage, M.J.5
  • 13
    • 0037085753 scopus 로고    scopus 로고
    • The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
    • Kanthou C, Tozer GM, (2002) The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood 99: 2060-2069.
    • (2002) Blood , vol.99 , pp. 2060-2069
    • Kanthou, C.1    Tozer, G.M.2
  • 14
    • 27644466314 scopus 로고    scopus 로고
    • Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling
    • Vincent L, Kermani P, Young LM, Cheng J, Zhang F, et al. (2005) Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. J Clin Invest 115: 2992-3006.
    • (2005) J Clin Invest , vol.115 , pp. 2992-3006
    • Vincent, L.1    Kermani, P.2    Young, L.M.3    Cheng, J.4    Zhang, F.5
  • 15
    • 0035064594 scopus 로고    scopus 로고
    • Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
    • Galbraith SM, Chaplin DJ, Lee F, Stratford MR, Locke RJ, et al. (2001) Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res 21: 93-102.
    • (2001) Anticancer Res , vol.21 , pp. 93-102
    • Galbraith, S.M.1    Chaplin, D.J.2    Lee, F.3    Stratford, M.R.4    Locke, R.J.5
  • 16
    • 34447330454 scopus 로고    scopus 로고
    • The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis
    • Roberts ZJ, Goutagny N, Perera PY, Kato H, Kumar H, et al. (2007) The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. J Exp Med 204: 1559-1569.
    • (2007) J Exp Med , vol.204 , pp. 1559-1569
    • Roberts, Z.J.1    Goutagny, N.2    Perera, P.Y.3    Kato, H.4    Kumar, H.5
  • 17
    • 0033565644 scopus 로고    scopus 로고
    • Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice
    • Ching LM, Goldsmith D, Joseph WR, Korner H, Sedgwick JD, et al. (1999) Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice. Cancer Res 59: 3304-3307.
    • (1999) Cancer Res , vol.59 , pp. 3304-3307
    • Ching, L.M.1    Goldsmith, D.2    Joseph, W.R.3    Korner, H.4    Sedgwick, J.D.5
  • 18
    • 0037068317 scopus 로고    scopus 로고
    • The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice
    • Zhao L, Ching LM, Kestell P, Baguley BC, (2002) The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. Br J Cancer 87: 465-470.
    • (2002) Br J Cancer , vol.87 , pp. 465-470
    • Zhao, L.1    Ching, L.M.2    Kestell, P.3    Baguley, B.C.4
  • 19
    • 0037125028 scopus 로고    scopus 로고
    • Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid
    • Ching LM, Cao Z, Kieda C, Zwain S, Jameson MB, et al. (2002) Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid. Br J Cancer 86: 1937-1942.
    • (2002) Br J Cancer , vol.86 , pp. 1937-1942
    • Ching, L.M.1    Cao, Z.2    Kieda, C.3    Zwain, S.4    Jameson, M.B.5
  • 20
    • 65249123159 scopus 로고    scopus 로고
    • Antivascular actions of microtubule-binding drugs
    • Schwartz EL, (2009) Antivascular actions of microtubule-binding drugs. Clin Cancer Res 15: 2594-2601.
    • (2009) Clin Cancer Res , vol.15 , pp. 2594-2601
    • Schwartz, E.L.1
  • 21
    • 0041421003 scopus 로고    scopus 로고
    • Combretastatin A-4 analogues as antimitotic antitumor agents
    • Nam NH, (2003) Combretastatin A-4 analogues as antimitotic antitumor agents. Curr Med Chem 10: 1697-1722.
    • (2003) Curr Med Chem , vol.10 , pp. 1697-1722
    • Nam, N.H.1
  • 22
    • 0142036683 scopus 로고    scopus 로고
    • Evaluation of antimitotic agents by quantitative comparisons of their effects on the polymerization of purified tubulin
    • Hamel E, (2003) Evaluation of antimitotic agents by quantitative comparisons of their effects on the polymerization of purified tubulin. Cell Biochem Biophys 38: 1-22.
    • (2003) Cell Biochem Biophys , vol.38 , pp. 1-22
    • Hamel, E.1
  • 23
    • 0032778424 scopus 로고    scopus 로고
    • Flavone acetic acid induces a G2/M cell cycle arrest in mammary carcinoma cells
    • Panaro NJ, Popescu NC, Harris SR, Thorgeirsson UP, (1999) Flavone acetic acid induces a G2/M cell cycle arrest in mammary carcinoma cells. Br J Cancer 80: 1905-1911.
    • (1999) Br J Cancer , vol.80 , pp. 1905-1911
    • Panaro, N.J.1    Popescu, N.C.2    Harris, S.R.3    Thorgeirsson, U.P.4
  • 24
    • 0026695774 scopus 로고
    • Actin based motility on retraction fibers in mitotic PtK2 cells
    • Mitchison TJ, (1992) Actin based motility on retraction fibers in mitotic PtK2 cells. Cell Motil Cytoskeleton 22: 135-151.
    • (1992) Cell Motil Cytoskeleton , vol.22 , pp. 135-151
    • Mitchison, T.J.1
  • 25
    • 0026643589 scopus 로고
    • Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis
    • Jordan MA, Thrower D, Wilson L, (1992) Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J Cell Sci 102 (Pt 3): 401-416.
    • (1992) J Cell Sci , vol.102 , Issue.Pt 3 , pp. 401-416
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 26
    • 56249107716 scopus 로고    scopus 로고
    • Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate
    • Orth JD, Tang Y, Shi J, Loy CT, Amendt C, et al. (2008) Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol Cancer Ther 7: 3480-3489.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3480-3489
    • Orth, J.D.1    Tang, Y.2    Shi, J.3    Loy, C.T.4    Amendt, C.5
  • 27
    • 44849127993 scopus 로고    scopus 로고
    • Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5
    • Shi J, Orth JD, Mitchison T, (2008) Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. Cancer Res 68: 3269-3276.
    • (2008) Cancer Res , vol.68 , pp. 3269-3276
    • Shi, J.1    Orth, J.D.2    Mitchison, T.3
  • 29
    • 84875370341 scopus 로고    scopus 로고
    • p38 MAPK is required for the antitumor activity of the vascular-disrupting agent DMXAA
    • Wu Q, Quan H, Xu Y, Li Y, Hu Y, et al. (2012) p38 MAPK is required for the antitumor activity of the vascular-disrupting agent DMXAA. J Pharmacol Exp Ther.
    • (2012) J Pharmacol Exp Ther
    • Wu, Q.1    Quan, H.2    Xu, Y.3    Li, Y.4    Hu, Y.5
  • 30
    • 1042263997 scopus 로고    scopus 로고
    • Induction of tumour necrosis factor and interferon-gamma in cultured murine splenocytes by the antivascular agent DMXAA and its metabolites
    • Wang LC, Reddy CB, Baguley BC, Kestell P, Sutherland R, et al. (2004) Induction of tumour necrosis factor and interferon-gamma in cultured murine splenocytes by the antivascular agent DMXAA and its metabolites. Biochem Pharmacol 67: 937-945.
    • (2004) Biochem Pharmacol , vol.67 , pp. 937-945
    • Wang, L.C.1    Reddy, C.B.2    Baguley, B.C.3    Kestell, P.4    Sutherland, R.5
  • 31
    • 0025109181 scopus 로고
    • Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts
    • Belmont LD, Hyman AA, Sawin KE, Mitchison TJ, (1990) Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell 62: 579-589.
    • (1990) Cell , vol.62 , pp. 579-589
    • Belmont, L.D.1    Hyman, A.A.2    Sawin, K.E.3    Mitchison, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.