Inhibition of the heat shock response by PI103 enhances the cytotoxicity of arsenic trioxide

Toxicological Sciences

Volumn 128, Issue 1, 2012, Pages 126-136

  Yih, Ling Huei ^a   Hsu, Nai Chi ^a   Kuo, Hsiao Hui ^a   Wu, Yi Chen ^a  

^a INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

Author keywords

Apoptosis; Arsenic trioxide; Cytotoxicity; Heat shock factor 1; Heat shock response

Indexed keywords

2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; ARSENIC TRIOXIDE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; SERINE;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; EMBRYO; HEAT SHOCK; HUMAN; HUMAN CELL; HYPERSENSITIVITY; IMMUNE DEFICIENCY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SENSITIZATION; TRANSACTIVATION; TRANSLOCATION LINE; WILD TYPE;

ARSENICALS; BASE SEQUENCE; BLOTTING, WESTERN; CELLS, CULTURED; DNA PRIMERS; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FURANS; HEAT-SHOCK PROTEINS; HEAT-SHOCK RESPONSE; HUMANS; OXIDES; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PYRIDINES; PYRIMIDINES; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84864151690     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs130     Document Type: Article

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